SEROQUEL Reviews (QUETIAPINE FUMARATE)

Average Rating: 2.9 (1505 Ratings)

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 ANTIPSYCHOTICS ANTIMANICS

 Type: Rx Drug

  

SEROQUEL  (QUETIAPINE FUMARATE):  This medication is used to treat certain mental/mood conditions (such as schizophrenia, bipolar disorder, sudden episodes of mania or depression associated with bipolar disorder). Quetiapine is known as an anti-psychotic drug (atypical type). It works by helping to restore the balance of certain natural substances (neurotransmitters) in the brain. This medication can decrease hallucinations and improve your concentration. It helps you to think more clearly and positively about yourself, feel less nervous, and take a more active part in everyday life. It may also improve your mood, sleep, appetite, and energy level. Quetiapine can help prevent severe mood swings or decrease how often mood swings occur.   FDA Approval Date: 2005-10-04 (Sources: U.S. Centers for Medicare Services, FDA)

  

Results are sorted by Age from youngest to oldest (reviews with no age reported listed first).

Key to Ratings: 1=LOW (I would not recommend taking this medicine.)
5=HIGH (this medicine cured me or helped me a great deal.)

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More on SEROQUEL: Reviews Summary  |  Drug Safety Information

RATING  REASONSIDE EFFECTS FOR SEROQUELCOMMENTSSEXAGEDURATION/
DOSAGE
DATE ADDED
 
 4  Insomnia caused by Anxiety Disorder Only bad side effect has been weight gain. I suffer from generalized anxiety disorder which at times has majorly interfered with my life. I was put on seroquel following a severe adverse reaction to Paxil. I have gained weight on seroquel. I am not sure how much weight can be attributed to this drug as I am also taking a Beta Blocker. My initial dose of seroquel was 50mg nightly for insomnia. Now I take 100-150mg before bedtime. However, I feel this drug really helps me to feel calmer which is a major advantage of taking seroquel. I would rather be a few pounds heavier and feel mentally relaxed than feel anxious and unable to sleep. F 25 4 months
100 MG 1X day
10/15/2012
 4  BPD II, depression, insomnia, mood Some restlessness during the night. First night woke up several times and had some trouble getting back to sleep. Second night woke up less times during the night and fell back asleep easier. Did have some night sweats. Was very groggy in the morning after the first night and somewhat out of it. Second night I made sure to sleep longer (10 hrs) and felt much better, less groggy. After half a can of red bull felt great! Did have severe headache on first day. Feel less hungry in general. Some dry mouth, I just drink more water :) Recently diagnosed with Bipolar II w/manic episode and rapid cycling, depression, mood disorder, anxiety. Had insomnia, anxiety, and BPD for years undiagnosed and managed them with other substances. Been on lamictal 100mg for 2 mos, and just started titrating up to 200mg. Right now on 150mg lamictal, flexiril 5 mg and vicodin 5/500mg for back and hip injury in car accident. Since taking seroquel I take flexiril and vicodin only as needed. This drug was prescribed as a sleep aid after being on Ambien 10mg for about 1yr and was no longer effective. Even thought I have taken this drug for only 2 days I feel great! I feel so happy again and feel like my old self, the person my husband fell in love with. I am joking and happy-go-lucky again. I feel much less anxiety, agitation, and irritability throughout the day. I would get so angry and anxious and have serious mood swings that the lamictal alone couldn't control. If prescribed this drug, try it and perhaps keep a journal of your symptoms. It seems this medication is right for only a small population of people w/our problems. So far the benefits outweigh the side effects for me, but i will monitor my feelings and symptoms closely. All I know is I am excited and happy for what may come :) F 25 2 days
25mg 1X day
2/4/2010
 4  Bipolar II/Depression Weight gain, hungover feeling, dizziness, MEMORY LOSS, appetite only increases if I take it at night and do not immediately fall asleep. VERY TIRED THROUGH OUT THE DAY. Seroquel has greatly helped my bipolar disorder and I have had great results with it. However, after a year and a half of being on it I'm still very tired during the day and need to be in bed for a total of 9-10 hours. Still a struggle to get up after that, but if I don't I feel very hungover all day long. I do not experience in increase in hunger if I take the meds when I'm in bed and about to fall asleep. It takes a bit for the meds to kick in, but if I'm already trying to go to sleep, then I don't have the urge to eat something. I would like to find something that doesn't make me as sleepy and will help with my memory loss, not make it worse. But for now, this will have to do. F 25 1.5 years
400 mg 1X day
5/1/2010
 4  bi-polar,OCD,anxiety,depression When I haven't had enough sleep I feel grogy for the first part of the day. Dry mouth.Recently(in the last year) I have gained 18lbs. I find that I am hungry ALOT, and I never ate alot.I have a few muscles spasms,mainly in my hands.Constipation. The first 6 to 7 months I was unable to achieve an orgasm. OMG! But it corrected itself, or I wouldn't be on it. Though there are side effects, seroquel has helped me like no other pill has before. I went through so many pills trying to find one to "fix" me. Seroquel has done that. It controls my racing thoughts at night so I can sleep, and controls my mood swings. Though there are major withdraw symptoms if my perscription is late, it dosen't take but two days and things are normal. I keep a regular check on my sugar because diabetes are in my family. But have had no problems yet. The only problem Is the weight gain. If it levels out and dosen't get to drastic, then I don't care. I would recomend seroquel to anyone needing help with depression,bi-polar,anxiety,OCD. It effects everyone differently, and I think it's worth a try. I can honestly say, if I had not found my doctor and been perscribed Seroquel, Then I wouldn't be here today. Hope this helps. M 25 3 years
450mg 1X day
4/26/2010
 4  insonima and high anxiety it would turn me into a zombie state so i could only take it just before going to bed. its really helped with being able to sleep and my overall anxiety is a bit lower. I havent had any side affects from seroquel. F 25 3 years
600 mg 1X day
4/7/2011
 4  bipolar disorder Sedation and confusion 30 - 60 minutes after ingestion, difficulty waking up, extreme confusion after waking up, forgetfulness At first I thought this was a wonder drug - after suffering from a nervous breakdown it made life bearable, 'took the edge off', helped me sleep, helped me get through the day, gave me a lot of mental clarity that I had been missing. I started on 100mg, taking 25 throughout the day as needed, ended up at 600mg (slept faaar too much), came back down to 400mg about 8 weeks ago and have slowly had to come down to 75 - 150mg as needed since then as I was having major problems with sedation, completely oversleeping (missing work etc.), being unable to be woken by others, etc. I have difficulty sleeping without it, and if for some reason I don't take a dose I get hypomanic the next day. I find it helps me heaps, and I haven't had the issues with weight gain that others seem to have had (in fact my weight has dropped drastically), but it's become obvious to me that over time it has completely screwed my memory - I forget words, names of people I have known for years, my own phone number, w F 25 10 months
6/24/2007
 4  bipolar II Apetite increase after night dose (450mg)Cannot control food intake--so hungry, to the point I don't care about my fat bum; like wead withought the high. Gained about 10 pounds. When I start falling asleep my body feels figgity, can't explane it very well; like if you overdosed smth... One of the best mood-stibelisers I have tried. (Kill zyprexa, put on 30 pounds in half an year) F 25 1 days
1/17/2005
 4  Bipolar Sleepiness Great drug, I will start tapering off of it after being on it for a year. Take 200mg at bedtime, now taking 100mg for a month or two and going from there! M 25 1 years
7/7/2004
 4  mood swings - bipolar symptoms (Note : this is the rest of the rating posted below)...a bad shape either, so this shouldn't be happening). 4. I have noticed some weight gain, but I'm not sure how much is due to the drug 5. Some hair loss (hair on the floor, the sink, the tub!) 6. Reduced sex drive but the sex is still great ! 7. I cry VERY easily! I used to cry easily before the drug but now it's 10 times worse. 8. I get agitated and frustrated very easily too... That's it! I think... It has definitely improved my quality of life... F 25 1.5 years
4/18/2007
 4  mood swings - bipolar symptoms 1. The worst of ALL : STUFFY NOSE !!!!!!!!! I don't understand why only a few people mention it! I used to take 400mg at bedtime, now I take 300 and 20-25 min, after I take it (as soon as it starts working and you begin feeling sleepy) my nose stuffs up completely! Then, I feel like I'm gonna have a panic attack unless I use a decongestant... 2. If I wake up in the middle of the night , 9 out of 10 times I'll go straight to the fridge for cereal or chocolate !!!! I never did that before! Fortunately or unfortunately as soon as I try to do the simple task of opening the cereal box, or pouring the milk, I start to get extreme heart palpitations and feel like I'm going to have a panic attack or even a heart attack!I'm only 25 ! So what I do is go straigt to bed and fall asleep in seconds 3. No energy, no stamina. I try to walk up the subway stairs and can hardly make it anymore without my heart racing like crazy and me being totally out of breath ( I'm not a fat person at all, and not in It has definitely improved my quality of life... F 25 1.5 years
4/18/2007
 4  Anxiety; Depression; Mood Swings Drowsiness; dizziness Love the drug; it has made me feel like a normal person again. I take Prozac as well as Seroquel in order to subside some of the violent mood swings one may experience as a side-effect of fluoxetine. Great medication; recomend it highly. M 25 2 months
2/9/2008
 4  bipolar/insomnia WEIGHT GAIN!!!!! Bloated feeling, blurred vision. Started taking this since I have horrible insomnia. I sleep for at least 12 or more hours! Its hard to get up in the morning and when I do im groggy. Weight gain is minimal but I cant stand looking like im 5 months pregnant due to the bloat and weight. Im scared to come off it due to the insomnia, but Im going to try something else. Im on 100 mgs a night. F 25 2 days
3/21/2008
 4  BP, Anxiety, Sleep, Withdrawals Always tired, couldn't wake up in the morning, weight gain, restless leg syndrome 1 1/2 hours after taking if I didn't fall asleep. I just want people to understand YES seroquel is a strong sedative. HOWEVER it DOES have use and many people benefit from it. These are people in the psychward. No this is not a joke. When I was there this stuff was handed out like candy. I had never even heard of it but I'd estimate at least 50-60% of people in there were on a certain dose. I knew this from when it was med time at night. It helped for schizophrenia, schizotypal, hallucinations, wasn't that great for the biplor patients but helped for the manic states, insomniacs (who were often depressed and tended to amplify depression but they were often put on other meds to combat it), extremely high BP that beta blockers alone couldn't lower, stopping seizures from withdrawal and psychosis. Most people gained weight while on it. Most people were in a perpetual sedated state. But the bad ones were the ones above 600-1200mg ed. In the ward is great for many reasons. But on the streets theres other better meds to take that don't work M 25 4 months
3/24/2008
 4  PTSD Weight gain. Fatigue - particularly in the A.M. I have a severely diminished sense of time passing. It helps with the worry, anxiety and feeling of doom - but at a price. I am on a very low dose but it seems to make me a bit "zoned out" - particularly time just passes without my taking any notice - I just think think to myself: "where did the day/night go? - how did it get to be 11:00 PM?" I've been given a second shot at life - I hate to think of it just passing by without me having the ability to appreciate it. Docs say the Seroquel has less severe side effects than other meds they could give me - it's all a balancing act: the horrors of PTSD or the side effects of the meds. I'll definitely take the sides! M 25 3 months
11/8/2008
 4  bipolar disorder weight gain. 10 lbs in 2 months. always been skinny never gained weight. eat whatever i want until now M 25 2 months
2/23/2009
 4  BPD (bi polar) Crazy dreams, I wake up groggy, however the feeling passes with a few cups of coffee. Besides that all side effects are good ones so far. I feel happy able to play with my kids, laugh and work with a clear mind. Used to want to drink alchol every day most often apon first waking up in the morning, now I couldn't be bothered to. Will update as I continue taking this medication,so far it has been a wonder.. F 25 2 months
11/8/2009
 3  Bipolar Disorder Loss of appetite, loss of libido, nightmares, excessive weight loss. I took Seroquel for about 8 months along with Effexor for 6 months & added Wellbutrin the last 2 months. I quit my medication "cold-turkey" without talking with my doctor because I felt like a "Robot Zombie". I would recommend you really research any medications you may take. I had horrible, severe dreams & nightmares. The dreams felt very real & often put me in a state-of-mind when I awoke that nothing was real. I also during my 8 months, experienced "visual disturbances". I lost 30lbs at the most & had no appetite. Being petite, I looked sickly skinny. On the brighter side, I did feel that I was a "better" person on medication as my mood swings have ruined friendships & relationships. Currently, I am not on any medication but will be seeking the advise of a therapist soon. I just don't want to feel like a robot or zombie anymore. It wasn't very pleasant. Another side-effect that I did not see posted, for those of you who paint, write, draw or are otherwise considered creative, while on medication...I could NOT for the life of me write, draw or paint. It "went away"....I have not taken any type of anti-depressant or anti-psychotic since...it's been 3 years since I stopped taking anything & I am JUST getting back was I lost. ;( Hope this helps. Thank you. F 25 8 months
7/28/2009
 3  Bipolar Disorder, Insomnia weight gain (25 lbs over 12 months), drowsiness, lackadaisical, very grumpy in the mornings, significant increased appetite and always for sweets or salts! My Doctor restricted me from using another sleeping aid until recently, as he liked that seroquel first an anti-psychotic and second a sleep aid. I will admit that I DEFINITELY slept while taking Seroquel. I originally started this drug at 25 mg, and have taken as much as 300 mg. For the last six months I have taken 100 mg (less than this is not effective for me for sleep) combined with a cocktail of other drugs for bipolar disorder. Taking this drug, but after a year the hangover and oversleeping had to stop. I gained a significant amount of weight (I exercise about 4 to 5 times a week in hopes to off-set the weight gain from increase from the icreased appetitie- not successful). I just recently switched to Lunesta (and take 600 mg lithium for bipolar). So far so good! And it's so nice not to crave sweets right before bed. M 25 13 months
12/14/2009
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 3  insomnia, GAD coma-like sleep, weight gain, ravenous appetite Reading all these comments has me sitting at my computer in tears... I thought no one understood what I was going through and I had never attributed my weight gain or eating habits to this drug. Like some others have said, this is a miracle drug for me- after two years of intolerable insomnia, this is the only thing that's worked. Once asleep nothing can wake me up- I once woke up to find my water glass shattered on the hardwood floor around my bed and had no recollection of it breaking. The cravings start about 1 hour after taking it (100mg) and I will eat ANYTHING and not even remember it the next day (I have to look for clues: crumbs in the sheets, empty ice cream cartons in the trash, candy wrappers strewn about my bed-side table). I've gained about 40 pounds in the past two years, and am now on a strict diet. I do not buy anything but fruits and vegetables and I have honestly gorged upon two pounds of grapes in the absence of chocolate in the house... At least I'm maintaining my c F 25 2 years
4/15/2008
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 3  Insomnia Very tired all day. Sometimes i couldn't fall asleep and experienced strange side effects like rapid heart rate, tremors all over my body - felt like anxiety attack. Sore bones and muscles. Ringing in the ears so loud I couldn't fall asleep. Jerking of the body. High cholesterol levels, however I don't know if this is caused by the drug. I only took 25 mg to knock me out. Decided to quit taking the drug because the effects I was having in the middle of the night when I didn't fall asleep were scaring me. F 25 1 years
6/26/2005

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