IMBRUVICA Reviews (ibrutinib)Average Rating: 3.4 (9 Ratings)Filter ResultsCompare IMBRUVICA with similar:
Type: Rx Drug
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Results are sorted by Date added. Key to Ratings: 1=LOW (I would not recommend taking this medicine.) Page: 1 |
| RATING | REASON | SIDE EFFECTS FOR IMBRUVICA | COMMENTS | SEX | AGE | DURATION/ DOSAGE | DATE ADDED |
| 3 | For CLL | Since I started taking Imbruvica the diarrhea started. I stoped the treatment after 45 days. I lost 32 pounds. From December 2019 I still having the diarrhea, really don't know what to do. | M | 69 | 47 days 420 mg 1X day | 9/27/2020 | 5 | Small B cell lymphoma in nervous sy | Very few. Achy joints rarely. A little bit of bruising. Small price to pay for feeling well | Miracle drug for me. I had relapsed 3 yrs ago and was weak and sleeping most of the afternoon and was down from 125 lbs to 98 ! Yikes!! One week after starting imbruvica I felt like a new person. More energy, started to slowly gain Weight and feel normal. I'm back to 127 lbs. | F | 73 | 3 years 420 1X day | 8/21/2020 | 5 | Cll | Little rash on hand to start but going away. Other than that no side effects. How great is that lymph nodes are disappearing !! | M | 64 | 11 days 280 | 2/17/2020 | 3 | CLL | At the full 420 day mg dose, I was tired all the time, so I reduced after 4 months to 280 mg a day, still not great, I have been on 140 mg a day for last 2 months, its better. They can reduce dose on this, I don't know why they start so high, I read on a med site that the original dosing is for a 350 lb person, I weigh half that, maybe they need to dose by body weight. Already had high blood pressure, raised it more, so added another BP pill, but down on one now so blood pressure back to usual, so quit the extra BP pill too. | I think this is a good and effective drug so far. I just feel they run people off of it by not dose reducing when people have problems with it. My neighbor and I both started it about the same time, and he was fed up with sleeping so much, said not much point being alive if you sleep all the time, I told him to ask his Dr. about reducing dose, he didn't know you could. He reduced also and is better. | F | 62 | 10 months 140 1X day | 11/10/2019 | 1 | Cll | Bruising, feeling heart beating, bad fatigue, weird marks on skin that would come and go, cough, WBC count low but other numbers good | Previously treated with chemo, well tolerated, went into remission. Approximately 2 years later cll returned. Was hesitant to start drug but doc insisted it is better than chemo. Side effects started almost immediately. Lymph nodes did reduce in size. Was monitored by pulmonologist and cardiologist. Generally in good health prior to taking drug. Had high blood pressure for years but well managed with meds. Due to side effects continously raised concerns with oncologist. She said the longer you are on the drug the less side effects you will have. Two weeks ago my dad went upstairs and collapsed, could not be resuscitated. Medical examiner noted cardiac event as reason for death. Cardiologist called us perplexed because he saw my dad two weeks ago. No blockages, tests were normal. After his death I found a journal article written in Sept 2019 mentioning more cardiac deaths have been found in the cll population taking this drug and more studies should be done. I wish I saw or the oncologist saw this article sooner. | M | 65 | 6 months | 11/2/2019 | 1 | C.l.l. | Afib, thyroid, diabetic, low platelets, kidney, and in hospital now for one week , off of imbruvica and waiting for things to clear up. | Will not be going back on it ever. | M | 76 | 12 months 420 | 10/12/2019 | 5 | CLL | Back ache within 5 days of starting. Became disabling back muscle spasm that immobilized me for 3 months. Never had that before in my life. Also, slight suppression of neutrophils on Imbruvica. | As a result of my back issues (which may or may not have been related to starting Imbruvica, but I think they were), I dose-reduced myself after one month from the original full dose of 420 mg down to 140 mg. And I have remained at 140 mg ever since, for nearly 2 years. This drug has been phenomenal at suppressing my CLL! A real miracle drug. Blood work back to normal, lymph nodes and spleen back to normal, lymphoma B symptoms gone. If I have a short stoppage of the drug for surgery, all my symptoms return very quickly, and disappear just as quickly when I resume the Ibrutinib. | F | 64 | 20 months 140 mg 1X day | 6/17/2019 | 4 | CLL | High blood pressure, sinus infections, staph infections, swelling in ankles and feet, general tiredness and muscle pain,'headaches, Severe case of C Dif colitis due to overuse of antibiotics, low counts of RB, platelets and immunoglobulins. | I was in good physical shape but seem to be slipping due to the side effects. WBC almost back to normal. Wish I could reduce my dosage!! | M | 63 | 15 months 420 MG | 6/1/2017 | 4 | I have MCL | I bruise easily and bleed more if I get a cut | it has helped resolve my mcl issues thus far | F | 48 | 3 months 140mg | 9/7/2015 |
IMBRUVICA (ibrutinib): This medication is used to treat certain cancers (such as mantle cell lymphoma, chronic lymphocytic leukemia/small lymphocytic lymphoma, Waldenstrom's macroglobulinemia). Ibrutinib belongs to a class of drugs known as kinase inhibitors. It works by slowing or stopping the growth of cancer cells. Ibrutinib is also used to treat a certain problem that may occur after a stem cell transplant (chronic graft versus host disease). It works by weakening your body's defense system (immune system). FDA Approval Date: 2013-11-13 (Sources: U.S. Centers for Medicare Services, FDA)