OTEZLA Reviews (APREMILAST)

Average Rating: 3.2 (50 Ratings)

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 Type: Rx Drug

  

OTEZLA  (APREMILAST):  This medication is used to treat a certain type of arthritis (psoriatic arthritis). Apremilast is also used to treat a certain type of skin condition (moderate to severe plaque psoriasis). Apremilast belongs to a class of drugs known as phosphodiesterase 4 (PDE4) inhibitors. For the treatment of psoriatic arthritis, it decreases pain and swelling, and may help improve flexibility in the affected joints. For the treatment of plaque psoriasis, it may help to reduce the redness, thickening, and scaling of the skin that occurs with this condition.   FDA Approval Date: 2014-03-21 (Sources: U.S. Centers for Medicare Services, FDA)

  

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Key to Ratings: 1=LOW (I would not recommend taking this medicine.)
5=HIGH (this medicine cured me or helped me a great deal.)

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  Charts & graphs: Drug Safety Information

RATING  REASONSIDE EFFECTS FOR OTEZLACOMMENTSSEXAGEDURATION/
DOSAGE
DATE ADDED
 
 5  Psoriatic Arthritis Increased bowel actions and occasional feelings of nausea but worth putting up with. for results experienced. Otezla is a wonder drug for me. I cannot put into words how good I feel while taking it. My joint pain in my shoulders and arms have significantly decreased, and my quality of life has improved so much. I sleep much better as not awakening so much due to dull ache. I take with Mobic 7.5mg and I take them separately as felt more nauseous when taken together. Taking Otezla with dry crackers helps keep the seedy feeling away. So far I've lost 3kgs/7Ilbs which has been an added bonus, and noticed a definite change in my appetite which has reduced significantly. I no longer binge on sweet things. Not experienced any deppressed feelings or sadness as side effect profile of Otezla mentions. As a Nurse I am now a highly functional individual and long may this last. These drugs are not a, "One size fits all" and feel very blessed to be part of this clinical trial. F 53 17 days
30mg 2X day
5/13/2016
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 5  Psoriasis; Psa;Iritis Stomach upset when I first started taking; Since then, symptom free. This medication is a life saver for me! My psoriasis would never heal...just get worse. I had patches on knees, elbows, back of scalp, toes, fingers, hands. I couldn't function normally and was embarassed continually by others' questions and my constant inability to control itching. Within a very short amount of time, it disappeared completely. Now I notice flareups every now and then if I get a cold or flu. Then I just use clobetasol propionate ointment (also a prescription) along with the otezla and it clears up immediately. Couldn't be happier. ALthough now my doctors are trying to get me to take Humira for the PsA. I'm wondering if they are getting kickbacks or something because the Otezla is working so great! Of course I guess my joints could be suffering...I do still have the joint pain. I have read of so many different side effects of Humira, yet with the Otezla I have had none and do not have to take any of the lab tests to check for liver damage/etc. like you do for so many of the other drugs. Also, according to my rheumatologist, iritis is associated with psoriatic arthritis. Previously, I have had SEVERAL painful outbreaks of Iritis and the only thing that would get rid of it is to have medication injected directly into my eye. Since taking Otezla, I have not had and outbreak of iritis!!!!!!! I couldn't be happier. :) F 45 1 years
30 mg 2X day
3/12/2016
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 4  Psoriatic Arthritis Stomach ache, loose stools I feel it has helped some. I am waiting to be on longer to see if I can get more relief. I am hopeful. F 60 1 months
30 mg 2X day
11/20/2015
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 3  psoriatic arthritis nausea, headaches at first, but diminished after 6 weeks cleared up my psoriasis wonderfully, but have had to add methotrexate back (I was taking Enbrel and methotrexate for 11 years...). Otezla alone did not help swelling and joint pain...I felt as if I was back at "square one"...hope adding the methotrexate helps soon. F 66 4 months
30mg 2X day
11/12/2015
 5  Psoriatic Arthritis Mild headaches, some insomnia, and some stomach upset. Yes a few side effects, BUT it works FANTASTIC. My fingers were swollen like sausages and that is gone. I thought I had joint damage, but they have returned to normal. I did not want to try conventional DMARD's due to the nasty side effects. The biologics all seem to eventually stop working so I wanted to resort to them last. Otezla has been working and I am very pleased. Not everyone is the same, but nothing ventured nothing gained. M 53 3 months
30mg 2X day
8/10/2015
 4  Psoriatic arthritis & psoriasis My skin is AWESOME since taking, but the arthritis doesn't feel different. I'm hoping it will stop or slow the progression. Still get stomach aches and have to go to the restroom within 2 hours. For the improvement of my psoriasis alone it is worth it!! F 50 6 months
60
5/13/2015
 1  Plaque Psorisi Diarrhea , nausea My condition remains the same. I also receive laser treatments 2x per week. M 68 40 days
30mg 2X day
5/5/2015
 2  Psoriatic Arthritis GI SYMPTOMS: Strong abdominal pain starting 2 hours after administration and lasting until 6-7 hours after administration. These symptoms I partially relieved by taking rantidine, either with the drug, or just as soon as the abdominal the pain began. The adbominal pain was made *way* worse by taking it with an NSAID, so I had to stop NSAIDs just to continue to test Otezla. Persistent softer stool, usually bowel movement about 1 -2 hours after administration. The GI side effects did not get better with time in my case; I took the drug for 2 months. CNS SYMPTOMS: Headaches, but those improved after only a few days. While I took the drug, I had persistent dulled thinking, worsened memory, and worsened ability to remember what I did (retrograde amnesia), worsened ability to remember words including common words like "railing" (aphasia), and a degree of forgetfulness and confusion. If I stopped the drug for 24 hours, these Cognitive symptoms would wane away. I will po The drug helped for the psoriatic arthritis pain only, but I have a prior existing heretofore unnamed connective tissue autoimmune disease that it did not help, but Enbrel did. It worked better for psoriatic arthritis than Enbrel. Incidentally, I also have taken Xeljanz for 3 months and that was similar to this drug in that it worked for the psoriatic arthritis better than Enbrel, but didn't help my other autoimmune disease. M 37 60 days
30 mg 2X day
9/6/2014
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 5  Inflammatory Spondylarthopathy Started off with pretty bad stomach aches but that went away after about 2 weeks. Now....I really don't have any side effects. My SED rate is down from 67 to 16 woo hoo!! F 3 months
30 mg 2X day
9/4/2014
 3  psoriatic arthritis feeling of anxiety, being speeded up not feel lucid. F 60 3 weeks
2x a day 2X day
9/3/2014
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