OTEZLA Reviews (APREMILAST)Average Rating: 3.2 (50 Ratings)Filter ResultsCompare OTEZLA with similar:
Type: Rx Drug
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Results are sorted by Date added. Key to Ratings: 1=LOW (I would not recommend taking this medicine.) |
Charts & graphs: Drug Safety Information
| RATING | REASON | SIDE EFFECTS FOR OTEZLA | COMMENTS | SEX | AGE | DURATION/ DOSAGE | DATE ADDED |
| 1 | Psoriasis | No side affects that were listed as possibilities, but I had psoriasis outbreaks in areas where I had never had outbreaks. In other words my psoriasis was worse after 10 weeks. | The monthly cost of $3,630.00 is not warranted based on my experience. U. S. Taxpayers probably paid for its research. | F | 78 | 70 days 30 mg | 6/22/2020 | 5 | Psoriatic Arthritis | Slight symptoms of diarrhea, chills, dry eyes. Fatigue. Major symptoms of insomnia and fight or flight- burning skin during physical exercise and anxious moments. | Reduced dosage to one a day in the morning stopped the insomnia at night. | M | 65 | 2 years 15 | 6/13/2020 | 2 | PsA | Nausea, stomach pain, acid reflux, diarrhea, joint pain and muscle pain. | I have been taking Otezla for almost 4 weeks. So far, no relief for arthritis. I have lost 4 pounds. I was walking daily prior to starting Otezla, but now I have so much muscle pain and increased joint pain, I cannot do it. My rheumatologist knows I am having side effects and I have an appointment next week to discusss. I was on methotrexate previously, but had to stop due to a new autoimmune disorder. My body aches and I feel like I have the flu. Good luck if you're taking this medication. Hope it works out for you. | F | 53 | 4 weeks | 6/1/2020 | 4 | Psoriasis | Diarrhoea, joint/muscle pain | 3 months in and I can see improvement in my skin, less flaking and much paler, hoping it continues to improve. I am experiencing joint and muscle pain and also hope it improves soon | F | 49 | 3 months 60mg | 12/11/2019 | 1 | Psoriasis | Leg pain, foot pain, tendon rupture | F | 49 | 2 weeks 30mg | 10/23/2019 | 5 | Psoriasis | Absolutely no side effects! | M | 72 | 4 years 30mg | 9/24/2019 | 1 | Psoriatic arthritis | Sick everyday. Moody, loss of interest in things I loved to do. Horrible adverse reaction mixing otzela with alcohol. Not a bigger drinker. Had some drinks (4) for a special occasion. Blacked out do not remember anything for a period of 6 to 8 hours | No warnings about this occurring. Do not mix otzela and alcohol. | F | 52 | 3 months 60mg | 7/31/2019 | 1 | Psoriatic arthritis | Been on this drug on and off. Was fine on the 30mg but my arthritis was still apparent so I upped it it as recommended by rheumatologist to 60mg. This made me have jaw pain, my arms, wrists were inflamed I’d wake up in the middle of the night in pain with them. I had sickness however it wasn’t as bad as they said it would be. I don’t know whether I should keep taking it in the hope it eventually works or to go off it completely. | Any advice would be amazing. I have also tried Humira before this however I was getting sick on it a lot so couldn’t take it anymore | F | 21 | 6 months 60mg | 4/26/2019 | 3 | Psoriatic arthritis | The usual stomach issues and diabetes for 4 weeks helped pustulars on hands and feet a lot but the last six months or so causes extreme muscle pain within an hour of taking I am going threw menapause as well maybe a connection muscles are weak and diminishing I see doc this month have to skip night dose at times to get relief but start to break out after a few days stiffness and pain is gone when I awake after skipping the second dose reported to otezla they said they haven’t had any of these reports I know my body and have read other testimony from otezla users with the same pain | F | 54 | 3 years 30 mg x da | 1/5/2019 | 4 | Psoriasis | Loose stools, Gas, Runny Nose, Nausea and some anxiety, moody | Has helped my scalp and face Psoriasis a lot. Started with 2 tablets per day but had bad mood swings and got completely off for about a year but tried it again but only one tablet a day. Seem to have less of the side effects so far after 4 months. | M | 62 | 4 months 1 tablet | 11/25/2018 | 5 | PSA and skin Psoriasis | None | I have minor PSA and psoriasis. It has helped with both conditions. | M | 60 | 4 months | 6/3/2018 | 2 | Psoriasis, atopic dermatitis | I started 6 months ago and had the usual GI side effects. I developed a hacking cough that I assumed were allergy related. Took all antihistamines and sprays. Nothing. Coughed to the point of throwing up. Once I linked the timeframe to starting otezla, I stopped for a week. Cough gone by day 2. Restarted after 1 week and cough back. Cannot sleep due to coughing. Stopping today after spending another night sleeping sitting up and praying facial lesions do not return | Cough is not listed USPI but found SPC (summary of product characteristics) and cough is listed as common. Would have been nice to know | F | 66 | 6 months 30 mg 2X day | 3/30/2018 | 4 | PsA | Unrelenting diarrhea; Bad stomach ache; Critically high BP | If it weren't for the side effects I'd give this drug a 10! I have terrible PsA. The arthritis is the worst - not bedridden, but very close. After just 3-4 days on this med the pain was 60% gone and after 6 days it was 90% gone. I would have stuck out the diarrhea and stomach aches but my blood pressure went to 190/90 in those short 6 days. I was able to bring it down somewhat with added BP drugs but never below 155/80. I normally am at 126/72 so I had to quit or risk blowing out a kidney, or worse. It works, however. Don't be afraid to give it a try. You may not have the issues that I did and you'll be playing ball again (!) | M | 71 | 6 days 20 mg 2X day | 1/11/2018 | 1 | psoriasis | After taking the 28 day starter dose, I’ve noticed several new problems. My diabetes has been under control for many years. Starting 10 days ago, no matter how much insulin I take it is barely lowering my blood sugar. Having psoriasis makes me unhappy, but out-of-control diabetes will wreak havoc. | I have also had a lot of trouble digesting my food, and I have suddenly acquired huge, swollen cold sores all around my mouth. My lips are 3 times their normal size. I’ve never seen anything like this. I am going to take a week or two off to see if these conditions clear up. | F | 74 | 28 days 30 mg | 12/30/2017 | 5 | Psoriatic Arthritis | Headaches, Nausea, Loose, more frequent bowel motions | I love Otezla. It works like a charm for psoriasis and arthritis. My skin is almost perfectly clear after 15 years and I have almost no joint pain. The side effects were a bit frustrating for the first few months, but now almost unnoticeable. No headaches any more, no nausea. I still have loose bowel motions but that's a good thing and it keeps my weight down. It's a way expensive drug, but I get it through insurance which keeps it manageable. I also take a low dosage of methotrexate but I am trying to convince my doctor that I don't need it. I'd like to do a three month trial to stop the metho and see how it goes. | M | 57 | 11 months 30mg 2X day | 11/16/2017 | 1 | PPPP & PSORIATIC ARTHRITIS | Ok i am extremely upset! I have been on/off this drug over a year, last yr around this time i got a horrible rash on my hands on tops down to wrists, pain my my breasts that is unbearable with 4 swollen lumps, i was set to go for a mamo and ultrasound but my breasts hurt so much I couldn’t imagine them squashing my dense breasts no way! Then the depression the past year of wanting to hide away in my room away from my family and wishing I don’t wake up and no explanation as to why! I have Palmer pustular plaque psoriasis and psoriatic and rheumatoid arthritis as well as fibro, well my last visit i told my dr and he for the first time in 6-7 yrs was very flippant saying see my general practitioner which he knows full well he treats me for everything because of all the autoimmune diseases so knows I don’t have another dr. I also am on oxycodone 20mg 4 x day, 10mg prednisone and .25 aderall, and hydroxine for itching. I decided to do my own experiment and stop the drug, well first off i knew my psoriasis would come back on my palms and soles, i figured ok some arthritis pain but hey i have pain meds, OMG i was in for a shock! Ok the plus side of 7 days off was my breasts quickly withjn 2 days stopped hurting and i can only find the original 2 lumps i have been monitored for yrs, my depression also gone! Now the bad parts, as expected my palms flared up my soles also but not as bad, but i got new pain i never in my life had all through my lower back, i also have | My understanding is many drs are playing ignorant in regards to the back pain and new rashes and breast pain! The rash & breast pain go away when i stop using it, but the constant pain i have and the back pain and gasping for breath is new, its like it escalated the costo | F | 47 | 2 years 30mg | 6/4/2017 | 4 | guttate psoriasis | i have a lot of stomach upsets and loose bowel movements I feel very achy like I have the flu. | My skin has improved immensely. The side effects are worth it for me as my skin was completely covered with psoriasis from head to toe and very painful. I am hoping the side effects will diminish | F | 49 | 8 weeks 30 2X day | 4/2/2017 | 4 | Psoriatic arthritis and psoriasis | Minor nausea 30 minutes after dose during 1st week lasting only 5 to 10 minutes. | Scalp psoriasis completely gone and only occasional itching although no lesions exist. Still hoping for more relief for inflammation in hands. Some improvement, maybe 20 % but definitely wanting more relief. | F | 51 | 2 months 30 mg | 10/15/2016 | 4 | PSa | Loose stool about 1 or 2 hr after morning dose...tolerable headache..slight nausea improved with time..insomnia | Arm pain gone...feet & hand pain improving...want to see what 3 month of dosing brings..hopefully even more relief..skin plaques behind ears & in scalp improved almost gone | F | 54 | 1 months 30 mg 2x d | 8/3/2016 | 1 | PsA | None | Unfortunately I was not one of the lucky ones. This didn't do anything for me. Doctor told me it's the safest drug for my disease. Started Humira which is working but worried about side effects. | F | 57 | 3 months 2X day | 7/26/2016 |