ARIMIDEX Reviews (ANASTROZOLE)

Average Rating: 2.5 (1431 Ratings)

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 ANTINEOPLASTICS AROMATASE INHIBITORS

 Type: Rx Drug

  

ARIMIDEX  (ANASTROZOLE):  Anastrozole is used to treat breast cancer in women after menopause. Some breast cancers are made to grow faster by a natural hormone called estrogen. Anastrozole decreases the amount of estrogen the body makes and helps to slow or reverse the growth of these breast cancers.   FDA Approval Date: 1995-12-27 (Sources: U.S. Centers for Medicare Services, FDA)

  

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Key to Ratings: 1=LOW (I would not recommend taking this medicine.)
5=HIGH (this medicine cured me or helped me a great deal.)

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More on ARIMIDEX: Reviews Summary  |  Drug Safety Information

RATING  REASONSIDE EFFECTS FOR ARIMIDEXCOMMENTSSEXAGEDURATION/
DOSAGE
DATE ADDED
 
 4  Breast cancer / recurrence Aching joints,inability to sleep,numbness in arms & hands during night,dry skin & eyes.Loss of sex drive :( Weight gain which is still climbing :0 After first diagnosis I refused meds just had lumpectomy but I had a recurrence in same breast 3 years almost to the day .This time I had lumpectomy + radiation .For the first year on Arimidex I felt very few side effects ,mainly loss of sex drive and loss of quality sleep.Now my arms & hands go numb every night.It takes a while in the morning before I able able to clench my fists.I have had a few days when I am disabled by nausea and head aches.not sure if this is due to Arimidex. I would love to talk with others about their experiences so feel free to email me .I live in Australia. I take Arimidex at night.Its been 2 years now and I just got the all clear after mammo :) I thank God and the hard work of all the researchers that I have a reasonable quality of life F 52 2 years
1mg 1X day
9/1/2010
Email
 5  Early stage IDCC no nodes joint pain, bone pain I started taking Arimidex in 2003 and took it for the whole 5 yrs until 2008. I am amazed that some of the comments about this drug are so negative, especially from the people who have only been taking it for a few weeks, or even days. Of course I had days when I felt that I had every side effect listed for the drug, but I knew most of what I felt was anger or depression because of the cancer. I know drugs affect people in many different ways, but alot of the side effects people feel the first few weeks, months and even years are because of the disease, not the treatment. After going off the drug in 2008, I feel every bit as good as I did before getting breast cancer, and I am still cancer free. If your Dr recommends this drug for you, give it a chance, it may save your life. It did mine :) F 58 5 years
1X day
8/26/2010
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 4  Stage 2b breast cancer fatigue and depression, some joint pain, had total knee replacement and shoulder surgery during past five yrs, hair loss, weight gain, various illnesses and general feeling of being old. Several family members have had breast cancer and not lived five years to tell about it. I have made it the five years, so I would take it again and deal with the side effects. F 63 5 years
1mg 1X day
8/24/2010
 2  breast cancer joint & hip pain, tiredness most if not all the time now, weight gain not able to loose or stop even when dieting, short term memory loss, no libedo, feel old. had full hysteretomy & overies removed, was on tamoxifan no bad side affects can remember,will ask to go back on, feel better now read comments though now know what is a matter with me! made appointment to see doctor thought under active thyroid or worse! thank you all and god bless i am not alone. F 44 1 years
1mg 1X day
8/16/2010
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 5  stage 2 breast cancer I am about six weeks off of Arimidex after taking for 5years. I am still not feeling any better. Lots of nights sweats and joint pain. Cannot seem to lose weight. Hopefully will feel better soon. F 63
1 mg 1X day
8/15/2010
 1  breast cancer lumpectomy wake up too early. fixed it by taking pill in am. dry eye. cry more/ use to almost never cry. i wonder if i don't really need it. i read a woman say arimidex made her labia shrink a lot, and got exceedingly dry to the point she could not sit for long without discomfort, and had to apply lube just to sleep. F 58 3 months
1 mg 1X day
8/15/2010
 2  BC Stage 1, ER +, HR- no nodes I experience restless nights and forgetfulness(major) as I did going through menopause, my cholesterol is up, but my main problem is that my immune system has been severely compromised. I am always sick with whatever is going around. One complaint finishes and next starts. This started within weeks of finishing radiation and starting arimidex. I don't know which of the t/ments would be causing this.I don't take to the bed, but I might have the occasional rest. I was an extremely healthy, fit woman before BC, I had no risk factors other than being 59. I still try to keep my fitness up, but it is impossible to get any routine daily exercise going. Anyone else in the same situation? I have decided to take arimidex for 3 years because of the memory problem. My father had Alzthmer's and I have decided not to run headlong into the desease. F 61 18 months
1mg 1X day
8/13/2010
 2  breast cancer Heart shakes/flutters/vibrates. Cough. Occasional hoarseness. Cough. Arms went limp on 2nd day. Very weak legs and arms. Dry, thirsty, sore throat. Insomnia. Fatigue. Depression. Headache (dull). Less nausea than Tamoxifen. Joints hurt a LOT. Shaky body. Chemical taste in mouth. Dizziness occasionally. General chest pain. I don't like it. F 52 5 days
1 mg 1X day
8/12/2010
 3  Stage IIIc BC, ER +, HER - Started as hot flashes, insomnia, & mild knee pain. Now have debilitating pain in my knees and ankles which causes mobility and balance issues. Had to have trigger releases done on both thumbs in the last six months. Also having elbow and neck stiffness coupled with neuropathy which is still present in my toes from chemotherapy. Hot flashes & inablity to sleep more than 5-6 hours a night remain a problem. Use vaginal moisturizer for dryness but have also experienced tears. Memory and forgetfulness issues are embarassing at work. There have been days when I wake up with severe headache and call out that day. I noticed in the past month that I have gained weight and my ankles and feet swell every day to the point of being painful. Oncologist asks me what would be the better choice: Arimidex side effects or recurrance of breast cancer. I am just having a difficult time with having my first grandchild to enjoy and feeling like I am 90 years old. It seems like once I get up and move around my joints feel better but I also tire easily and have to sit down & rest. Then when I get up again, it starts all over again. NSAIDs help if I take dose first in morning but I am concerned that this joint pain will remain after finished treatment. Counting down the days to last dose of Arimidex! F 53 21 months
1mg 1X day
8/11/2010
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 1  stage 1, er, pr, her neu +3 Severe depression, hot flashes, fuzzy thinking, forgetfulness, joint pain, sensitivity to heat and light, gradual hair loss, weight gain controlled with exercise and diet, extremely dry eyes resulting in blepharitis with vision distortion. At first I could deal with the side effects but they seem to be increasing after 2 and a half years on this drug. My oncologist has told me that effects are not cumulative. I don't believe it because they have increased. This drug is too debilitating and aging. It is becoming more debilitating than either double lumpectomy, chemo or radiation. I am seriously considering alternative therapies. I am fearful that these symptoms will persist even when I stop taking this very scary drug. My oncologist also said that it has only be shown to prevent recurrence by 2 or 3 %. Has it really been tested to determine its true effectiveness? F 66
1 mg 1X day
8/10/2010
Email
 5  Stage IV breast cancer So far I have not experienced many side effects from this medication. I do have some fatigue and depression but minimal joint or muscle pain . I attribute the fatigue and depression to the fact that I am only one year post surgery / chemo / radiation. I expect my energy and mood to improve. Take it in the morning first thing . Any info on if it is better to take at night or morning? F 56 9 months
1mg 1X day
8/7/2010
Email
 5  following breast cancer surgery I don't think I experienced any side effects, though my memory is challenged -- don't know whether that's due to the drug or to stress or age or.... I do have osteopenia, which may be a result. I'll find out soon whether taking Fosamax kicked that problem. I don't discount others' reports of side effects, but I've been essentially unaffected. I'm actually nervous about going off it after 5 years. F 56 5 years
1 mg 1X day
8/4/2010
 3  Early stage DCIS Hyper-emotional, shoulder-elbow-finger pain, fatigue, malaise, sleeplessness, warm waves (hot flashes), low appetite, weight gain/no weight loss, altered life outlook, did I mention FATIGUE!!!!!!! Been on this WRETCHED medicine 7 mos. since Dec. 09. After first month I put myself on 1/2 tablet before onset of side effects. I cannot even fathom how much more miserable I would be if I were taking the full dose of 1 mg/day. Everyday I have to CHOOSE to take this poison! Make your own life choices ladies and don't regret or look back! One day soon I will decide to NOT TAKE IT and never regret it. My score was very favorable for doing nothing so taking this CRAP is a concession to my very empathetic surgeon and onc. If I come off of this crap I'm NOT going to take anything else! F 58 7 months
.5 mg 1X day
8/2/2010
 2  breast cancer terrible joint pain. esp. knees, feet and my hands. fatigue! I am 59 yr old and feel like I'm 90. I walk up and down stairs like I'm 90! Tired all the time. Memory is also bad! My mother had altzeimer's, so that really scares me. I sound like everyone else here. Joint pain, fatigue, memory loss,sleepless nights! F 59 1 days
1 mg 1X day
8/1/2010
 1  Metaplastic BC 1 cell slightly HER+ I'm considering my options. I'm fairly sure that the cancer will Mets to my lungs, or liver or bone & not much is known about it. I am only 58, my husband is 60 and disabled and I must continue to work. I find it very odd that every comment I see talks about the overwhelming fatigue, but in the official Arimidex website, fatigue is NOT mention... F 58 14 days
1mg 1X day
7/26/2010
 4  stage 1 bc no nodes stiff joints when I get up in the morning and when I get up from sitting. I also feel VERY tired most of the time. Once I get up a moving I feel OK. I ride my bike a lot and I run. While I am doing these I feel great. But I pay later with fatigue. If this is all from Arimidex and it is a sign the medicine is working, I will continue. I was worried the fatigue was from something else like new cancer. F 49 7 months
1 mg 1X day
7/25/2010
 4  Stage 2 HER neg breast cancer 2006 2007 first year joint pain and stiffness insonmia vivid dreams fatigue memory was cloudy couldn't remember names of some common items (ex. I wanted a screw driver and knew what I wanted but just couldn't tell my daughter what it was.Needed a stamp but couldn't remember what to call it. I knew what the item was but couldn't give anyone the name of it) 2008 After I "got use to it" stiffness in feet and ankles (I no longer drive because I'm afarid I'll have an accident) Painful knees and generalized aches.Have difficulty with stairs. Hair loss and thinning.Weight gain! sleep only 3 to 5 hours with vivid dreaming.High blood pressure,bone loss and occational depression. I refuse to take any anti depressants. I'm tired of xrays and the like. I'm surprised I'm not glowing in the dark! I feel like my life got sucked up!*I use to be very active. walked 5 miles a day and managed an apartment building. I can't do that anymore. I want to be me again! After 4 years I want to discontinue the Arimidex. I need to feel normal again but I am afraid of the cancer! I just want to be normal again! F 52 4 years
1mg 1X day
7/25/2010
 2  IIB Rare Metaplastic This is horrible.Couldn't sleep first few days but that passed.Now all week have had chronic, constant, incapacitating FATIGUE, mental confusion, eyesight problems, headaches.Worked all through chemo & rad. Have lupus & this fatigue far surpasses that or the chemo. Metaplastic breast cancer is RARE and made up of 3 different types of cells, and 1 cell tested "slightly" HER+. Plus oncologists know so little about it they don't really know how to treat it. Since it has only been 7 days since I started taking it, I am very hopeful (but doubtful as well), that at least the fatigue will pass. Have important job helping others file for Social Security Disability and have to remember rules & regs & be able to communicate clearly. MUST continue working as my husband is disabled at age 60 F 58 7 days
1mg 1X day
7/23/2010
 2  bc stage 1 joint pain. Especially knee & foot pain. tops of my feet feel like I have iv's in them. walk alot @ work, and at night the pain in my feel & legs keep me awake. Wearing pj's help my leg pain. Also have weight gain around the middle. I hate this drug, but my mom died of neck & spine cancer. My friend had bc and never took the drugs...now it is in her liver and panceas. So what do you do? So far, it is working. No re-occurance. I hope the side effects don't get any worse. I still have 2+ yrs to go. God bless you all. F 60 26 months
1 mg 1X day
7/21/2010
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 3  19mm Grade II DCIS, 1 lymph node Depression. Tearfulness. Finger joints swollen, hip Bursitis, stiff knees & feet. Memory worse. After 1st 3 months (stiffness, tiredness & memory loss) I tried Femara/Letrozole which made me feel badly depressed. Misery all the time. Back on Arimidex for 4 years but tiredness and tearfulness getting WORSE. Embarrassing. How about I go on to half a pill?? Don't want it back - I got HER2 pos on other side in 09, & only just finished Herceptin. F 73 4.5 years
1mg 1X day
7/20/2010
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