TOPAMAX Reviews (TOPIRAMATE)

Average Rating: 3.0 (1824 Ratings)

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 ANTICONVULSANTS

 Type: Rx Drug

  

TOPAMAX  (TOPIRAMATE):  Topiramate is used alone or with other medications to prevent and control seizures (epilepsy). This medication is also used to prevent migraine headaches and decrease how often you get them. Topiramate will not treat a migraine headache once it occurs. If you get a migraine headache, treat it as directed by your doctor (such as by taking pain medication, lying down in a dark room). Topiramate is known as an anticonvulsant or antiepileptic drug.   FDA Approval Date: 1996-12-24 (Sources: U.S. Centers for Medicare Services, FDA)

  

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Key to Ratings: 1=LOW (I would not recommend taking this medicine.)
5=HIGH (this medicine cured me or helped me a great deal.)

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RATING  REASONSIDE EFFECTS FOR TOPAMAXCOMMENTSSEXAGEDURATION/
DOSAGE
DATE ADDED
 
 2  migraine constant tingling in hands & feet, constipation & diarrhea, weight loss, jittery F 28 3 months
8/22/2005
 2  Migraine severe depression At first, it worked great! After a couple of weeks the effectiveness wore off, & my Dr. increased the dosage. It worked great again for a couple of weeks. It was no longer effective & I started getting severely depressed. So, I had to quit taking it. F 28 3 months
8/22/2005
 5  
8/12/2005
 3  migraine prevention At 100 mg. I am experiencing diarrhea, concentration problems, word-finding problems, fatigue, lethargy, weight loss, taste alterations, numbness and tingling in fingers and toes, dry mouth, some sexual dysfunction, stomach aches, wanting to sleep long periods of time with difficulty waking. At doses lower than 100 mg. I had a frequent sense of euphoria, an overall sense of well-being, a little bit of trouble sleeping and ease of waking. Have been taking Topamax for 5 weeks now and am now at the so-called maintenance dose of 100 mg. per day, 50 mg. in the a.m. 50 mg. in the pm. Have had 5 migraines since I started titrating dose 5 weeks ago. I generally get about 6 migraines per month. Would like to lower dose to 75 mg. per day if it will work, felt much better overall at that dose with hardly any annoying side effects. Love the weight loss. I feel like I've lost a bit of my personality at 100 mg. I feel sort of flat. Hate the fuzziness and lethargy. I do think it is working to reduce the number of migraines but am not sure yet. The jury is out. For sure I'll give it at least another month or two. The best drug for my migraines is an Imitrex injection. It works nearly every time. I also use Maxalt but it doesn't seem to be very effective any more. F 52 5 weeks
8/11/2005
 5  Migraines Tingling fingers- went away Lack of appetite - Improved when only took medication at night instead of splitting up in two doses Irritability - Not going away Fatigue- Still an issue I saw a comment that said Migraine miracle drug. From 9 Imitrex a month to no more than 2 a month now. I am still concerned about mood swings and appetite. M 40 6 months
8/8/2005
 5  depression, fibromyalgia tingling in hands and feet, weight loss , loss of appetite, which was great because the ssri drugs packed on 40 40lbs, insomnia too, but thats also my other med issues cant blame it on the topamx the fibromyalgia is a slep disorder, if anything it calms me. i am taking 100 mg twice daily...i am thrilled so far if it changes Ill re visit this site F 31 30 days
8/7/2005
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 2  Epilepsy tiredness, lack of concentration, moodiness, cardboard taste in mouth, tingling feeling in limbs. M 20 2 months
7/30/2005
 4  Complex Partial Seizures Heat intolerance, slight fatigue, tingling in my fingers, cannot drink any carbonated drinks, no appetite (not aware of weight loss yet), short term memory loss (not extreme), sometimes have trouble finding words, dry mouth and extreme thirst Currently at 50mg, and do not consider my side effects bad at all. They may seem like many, but are actually very insignificant as they aren't too severe (except the thirst). Have not had a seizure in 2 weeks, but am still having auras. Doctor may increase dosage in 4 weeks if my auras do not stop. Overall, I am pretty happy with this medicine :) F 21 17 days
7/28/2005
 3  Migraines Weight-loss (first 3 weeks only), stomach cramps, diarreah, sleeplessness, numb fingers, arm and leg cramps I have been working may way up the dosage scale, and I think it is starting to work...but there are a lot of side effects...I guess it is worth it to not have pain every single day, but now I have all these other problems. There is no end to things. M 26 6 weeks
7/25/2005
 1  bipolar Crying, irritablity, memory loss, vision blurry, suicidal thoughts, weightloss, irratic driving, and food tasted bad I tried this med twice in two years. It was horrible! There is a good reason that doctors nicknamed it F 34 2 months
7/22/2005
 1  preventative for migraines dizziness, nausea, extreme fatigue, hungry for high fat foods (burgers, cheese, ice cream), nerves F 28 11 days
7/19/2005
 1  Bipolar I was on the topamax (100mg/ day) because I gained 20 pounds in the first six months of taking Zyprexa. The side effects of topamax are HORRIBLE! I had intense rage and memory problems, hair loss, anorexia, and it also aggrivated a stomach ulcer and caused problems with my kidneys as well. Needless to say, the rage alone outweighed any benefits it was having on mood stablization. The appetite supression worked but was unnecessary due to the fact that I was also on Geodon, (40 mg 2x/ day) which did not cause the appetite increase like the Zyprexa so I didn't need anything else. I went off of the topamax, and all of the symptoms went away, except for the ulcer which I'm still dealing with. EVIL EVIL Topamax! I would not recommend Topamax to anyone, the side-effects (even the most common) FAR outweigh any benefits of this drug in my opinion. F 27 1 years
7/18/2005
 5  Bipolar 1 eye pressure, weight loss I was switched to topamax because my first cocktail of meds made me gain weight. I loved Topamax !! It helped my mood better than any other stabilizer Ive ever been on!! Plus I lost all the weight..But im off it now because im pregnant...I would recommend Topamax for anyone whose gained weight from mood stabilizers! F 25 1 years
7/16/2005
 3  migraines difficulty concentrating, insomnia, funny taste Migraines seem well controlled. However I am having trouble concentrating at work. There seems to be a slight appetite suppressant effect also- which is great. F 38 4 weeks
7/16/2005
 4  migraines dry mouth, not feeling like myself, weight loss At the present juncture I take 300 mg. in the am and in the pm. so that's 600mg. per day. I also take six other migraine related medications, such as Amerge twice a day. Reglan helps my nausea. I have been in 2 other drug trials.Topamax is still a relatively new drug and we need to learn more about it. Good luck everyone. F 37 3 days
7/14/2005
 1  Migraines severe memory loss and confusion, depression My senior year of highschool I began getting migraines. After trying multiple medications with no success, my neurologist prescribed Topamax. I was on it for approximately two years. (75mg/day)
At first, it seemed to be a Godsend, relieving my constant migraines to the point that I only had one or two every month. Then the side effects started. The biggest problem was I didn't realize they were side effects of the Topamax I was taking.
First, some key background information on myself: I was a member of the Gifted and Talented program, an athlete holding school records, and drum major of the band, amongst other achievements. I rarely missed class, and was for the most part an 'A' student.
Then I started failing. I barely passed my second semester classes. My parents just thought I was slacking off, as plenty of students due in their senior year. This wasn't the case. I didn't know what was going on, but I couldn't remember anything. I felt like I couldn't think.
It got worse.
I entered a university that fall. I failed all of my classes but one. I couldn't remember what days I had class or what those classes were, let alone what assignments were due. This continued for the rest of that school year and the next.
Fall of my sophomore year I began going to counseling. My emotions were completely out of control and I was still in very poor standing grade-wise. I had to carry my schedule and a map of the campus with me wherever I went, because I couldn't remember what buildings they were in or where those buildings were. I couldn't remember what day it was. I had hardly any friends, and spent the majority of my time alone in my room, either sleeping or staring off into space.
The side-effects came to their climax that winter, when I began having bouts of amnesia. I would leave the dorm to go to class, and a few minutes later I would find myself on the sidewalk, not knowing where I was going, where I was, or how I even got there. Eventually, after sitting down for a few minutes, I would be able to remember where my dorm was and find my way back.
Everything ended when on the morning of a final I woke up, had a seizure, woke from that about a half hour later, and ended up in the emergency room. I don't remember most of that day. After ruling out all causes, it was decided that it must be the Topamax. When I went to see my neurologist, she said it couldn't be the Topamax, and actually tried to up my dosage. I refused, and weaned myself off of it.
Now, about six months later, I am returning to my normal self. I can remember my class schedule and where everything is. My grades have improved a bit, and my social life as well. It's going to take awhile for my life to get back to normal. Thankfully my parents, family, and friends have been understanding.
Two years of my life are a confused blur filled with blank sections of memory. My college career is permanately scarred, and my mind might be as well. I don't care how well this medication works, I wouldn't wish what I have suffered through upon my worst enemy. This has been cross-posted. People need to know.
F 20 2 years
7/14/2005
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 1  Migraines Aches & pains throughout body, vivid dreams, continual fatigue(nodding off driving!), body spasms-SEVERE pain in my buttocks and lower back(felt like back labor 24 hours a day), loss of concentration, depressed, low feeling, agitation,irritatation, skin sensitivity, sore breasts, flu like symptoms, decreased memory. The pain I have experienced dealing with this drug is not worth it for me. There are other alternatives out there. I was on a low dosage (50mg) and was told to go up to 200mg. I can't even begin to imagine. F 47 23 days
7/13/2005
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 1  Depression / Weight control Aphasia, Memory Loss, Sleep irregularity, Irritability Leg cramps, stomach pain, Lethargy, Acne, Hair loss, Weight gain This has been a year of living hell. I have actually been binge eating on Topamax even though I had lost over 120 pounds on Atkins prior to starting Topamax. I have tried to atribute by side effects to other blood pressure meds I am on, but have finally come to the realization that the little pills I have been religiously taking to make myself better have turned me into a drooling idiot. The one positive is that my migrains have gone away, but there may not be much mind left to feel pain. F 43 1 years
7/12/2005
 3  migraine headaches dizziness, passing out (only lately), fogginess, mental confusion, extreme tiredness (only lately), good weight loss (lost 50 pounds on a 5'3 When I first started Topamax it seemed like a dream come true. It helped the migraines, nearly eliminating them, but now it doesn't seem to be very effective anymore. Due to the side-effects, I not only don't want to increase it, but I'm needing to decrease or get off it. It's causing me to pass out lately, and is causing dizziness like it did when I first started it. Other possible causes of this have been ruled out. It's also causing extreme fatigue lately and increasing confusion, memory loss, and forgetfulness. I have to write EVERYTHING down or I forget it the next damn minute. My friends and doctor have been so concerned about my passing out, they've even had me go through MRI's/MRA's, echocardiograms, tilt table tests, 30-day EKGs and even an EPS to make sure my heart is okay and everything is fine there...I've had to endure all of these tests because of the side-effects of this damn drug. I'm sure there's more that I've forgotten, but I'm too tired to continue ;) F 38 1 years
7/11/2005
 2  weight loss Hair loss none F 28 43 days
7/6/2005

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