ZANAFLEX Reviews (TIZANIDINE HYDROCHLORIDE)

Average Rating: 3.0 (125 Ratings)

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 ANTISPASMODICS ANTICHOLINERGICS

 Type: Rx Drug

  

ZANAFLEX  (TIZANIDINE HYDROCHLORIDE):  This medication is used to treat muscle spasms caused by certain conditions (such as multiple sclerosis, spinal cord injury). It works by helping to relax the muscles.   FDA Approval Date: 1996-11-27 (Sources: U.S. Centers for Medicare Services, FDA)

  

Results are sorted by Gender with females listed first (reviews with no gender reported listed before females).

Key to Ratings: 1=LOW (I would not recommend taking this medicine.)
5=HIGH (this medicine cured me or helped me a great deal.)

Page: 1 2 3 4 5 6 7


More on ZANAFLEX: Reviews Summary  |  Drug Safety Information

RATING  REASONSIDE EFFECTS FOR ZANAFLEXCOMMENTSSEXAGEDURATION/
DOSAGE
DATE ADDED
 
 4  Multiple Sclerosis None, other than slight drowsiness. I take it a bedtime to help with severe foot cramping. Works fairly well for relaxing muscles at bedtime. Other than short-term drowsiness, I've had no adverse side effects from Zanaflex or Tizanidine generics. M 50 5 years
3/27/2006
 4  Muscle contracture Excessive sleepiness, so I just use this as my "fall asleep" pill. This drug kicks in after 30 minutes and wears off after 4-5 hours. It puts me to sleep, so I use it to fall asleep. It does not help my muscles at all. As for helping my muscles, two other drugs I tried work better: Cyclobenzaprine (which is slow to kick in and too slow to wear off leaving me unable to wake up) and Skelaxin (which I can stay awake while taking). M 37 2 years
2 mg 1X day
9/30/2014
Email
 4  MS Sleepiness about 40minutes after taking a dose. I'll nap for 45minutes if there's nothing to occupy me. I won't notice drowsiness if I am occupied. Does a great job of moderating MS related spasticity without sapping muscle strength like baclofen does. M 55 5 years
12/26/2008
 3  Migraines caused by neck tension Dry mouth It has mitigated the intensity of my night headaches. Since taking this medication prior to going to sleep, I only get a smaller and shorter version of the migraines. I still sometimes need to sleep sitting up to keep the headaches from growing to full blown. Still if I weren't on Xanaflex I would be passing out and throwing up and all that has stopped thanks to this medication. M 61 6 years
7/16/2008
 3  severe shoulder/neck pain Brief drowsiness when I began taking them, but only lasted a week or so now I take max dosage staggered through out the day with very little if any effects. When I began taking I noticed they would extend the length of time I would benefit from trigger-point injections. Now I am not sure if the length of time has built a tollerence but I feel as though there is less benefit. M 36 9 months
11/26/2007
 3  muscle injury Disappointed with antispasmodic effect M 52 75 days
9/25/2003
 3  Fibromyalgia I had to stop taking this medicine because of an allergic reaction to it. For about 2 weeks, I was taking it and I gave it a rating a "3" in terms of helping to reduce my fibro symptoms. However, I broke out with a horrid rash and hives on the 3rd week. We had to rule out a Stevens-Johnson situation at first. That was the intial concern of my physician. However, after stopping the medicine, the rashes completely resolved themselves about one month after discontinuation. This was a RARE situation for me. I have no known allergies to everyday things (pollen, plants, foods, etc.) and I have no other medicine allergies. So this was just an unusual case. It was unfortunate also, because the med seemed to be helping me quite a bit and if I were not allergic to it, I would probably still be taking it. M 42 2 weeks
10/10/2006
 3  Fibromyalgia, multiple spinal discs Nightmares! I hate the nightmares! It works OK, but I have to fight sleep for hours, or I'll be staring in my own Sci-Fi/horror movie. Dry mouth - big time, but I can deal with that. I take it in emergencies, for really bad back pain, in addition to my regular pain meds. It helps, but I can't take it too close to bedtime, due to the side effect. M 40 10 months
4mg 2X day
6/6/2010
 3  Muscle spasms Dizziness slowed speech hard to walk but no pain at all take about 4 and you will be really high lmao that's what I use for M 44 2 months
4MG
5/8/2012
 3  Back and neck spasms Paraesthesia. Way too short 1/2 life. M 39 7 days
8mg. t.i.d
12/12/2016
 3  Thoracic injury Dry mouth. Dizzy. Severe itching. Seems to work well M 55 10 days
15 mg 2X day
5/12/2022
Email
 2  Spasticity Extreme tiredness yet unable to sleep well. Vivid nightmare I have ms with disabling spasticity in my legs. I have to use forearm crutches to get around and lately I haven't been getting around much at all. The first 2 days I took the Tizanidine I thought it seems like it's helping a bit. The third day though It didn't seem to help much at all but made me feel so so tired and unmotivated. I don't normally feel unmotivated kind of feel like it put me in a bad mood. It could be in part from the lack of sleep. I did have a nightmare that I was dying and then when I awoke there was a baby crawling on my ceiling. That part wasn't really scary just weird. M 54 3 days
5/2/2020
 2  Severe Back trap neck pain Felt like crap and didn’t help at all with pain. Felt like taking a Benadryl for no reason while in pain...also had nausea and did not help sleep. Garbage. M 29 5 days
4mg
10/26/2019
 2  Tension headaches Sluggishness and tired Doc called this in today, 4mg, told me to take one in the evening. Took the first one and noticed a little grogginess, but felt headache actually coming back and getting worse. About an hour and a half later, took a second one. So far useless, might call my doctor tomorrow. And worse off, I can't take the Fioricet he gave me b/c I really don't wanna mix the two and risk oversleeping tomorrow and missing work. M 29 1 days
4mg 1X day
6/29/2012
 2  Multiple Sclerosis Very detailed dreams which I enjoy, I take two 4MG pills before bed. Twice perhaps taking them to close to the middle pill, I became groggy and my wife checked my blood pressure and it was 60 over 40 I don’t think it helps the spasticity as I have been on baclofen for 2 years and nothing changed, but maybe it would be worse now, who knows M 74 6 months
4 MG 4X day
8/31/2010
Email
 2  Back pain None really It just didnt do much, it made me a little tired but no relief M 35 1 months
30 3X day
5/18/2010
 2  Neck Pain, CFS, Muscle Pain Involuntary bladder leakage, yeah wetting the bed, nightmeres, major sedation. Not a great medicine. I use it for sleep when I can't fall asleep. Otherwise, if you have neck pain that is not muscle related, this isn't your drug. I definately can see it being used as a sleep inducer, not sustainer. Trazodone'll do that. M 22 3 months
5/27/2007
 2  Fibromyalgia, Lumbar Disc Disease The medicine works great for spasms and spasticity. The problem was I could not achieve the theraputic dosage without feeling like I was going to faint every time I tried to stand. I still use it on very bad days when I know I'm not going to have to get out of bed. I break the pills in half and take 2mg every 4 hours. However, I have better luck with Valium and pain medication. I encourage anyone with Fibromyalgia to ask their doctor about Lyrica. M 34 3 months
10/31/2007
 2  Tension headaches Tired Does not seem to relax muscles in neck that are extremely tense. Just makes you tired. You sleep thru the pain i guess that could be a plus. M 31 1 years
5/6/2004
 1  Cervical Dystonia Zanaflex (Tizanidine) - I had 1 mg. (1/4th of a 4 mg. tablet). It caused a worsening of Cervical Dystonia and caused blurred vision. It also caused drowsiness and an inability to think clearly. This is an anticholinergenic. Zanaflex is not supposed to have any antihistamine in it, whereas Cogentin does. [Note: The half-life of Zanaflex is 2.54 hours]. The anticholinergenics that I have tried have either worsened the Cervical Dystonia or have not done anything to help it. M 52 1 days
1 MG. 1X day
5/8/2014

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