ZANAFLEX Reviews (TIZANIDINE HYDROCHLORIDE)

Average Rating: 3.0 (125 Ratings)

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 ANTISPASMODICS ANTICHOLINERGICS

 Type: Rx Drug

  

ZANAFLEX  (TIZANIDINE HYDROCHLORIDE):  This medication is used to treat muscle spasms caused by certain conditions (such as multiple sclerosis, spinal cord injury). It works by helping to relax the muscles.   FDA Approval Date: 1996-11-27 (Sources: U.S. Centers for Medicare Services, FDA)

  

Results are sorted by Gender with females listed first (reviews with no gender reported listed before females).

Key to Ratings: 1=LOW (I would not recommend taking this medicine.)
5=HIGH (this medicine cured me or helped me a great deal.)

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More on ZANAFLEX: Reviews Summary  |  Drug Safety Information

RATING  REASONSIDE EFFECTS FOR ZANAFLEXCOMMENTSSEXAGEDURATION/
DOSAGE
DATE ADDED
 
 1  Back pain nausea,dizziness,sore throat,muscle spasms, indigestion, severe anxiety,tinnitus,headache,chills.flu-like symptoms. Started out okay-slept a better but was constipated then the nausea,shaking and dizziness started around day 9-it got so bad I had to go to the emergency!I stopped the medication immediately but nearly a week later, I'm still getting all the side effects.It's worse after sleeping.These must be explained before taking the drug.I'm not taking it again F 60 10 days
2 mg 1X day
4/24/2023
 1  Muscle spasm Made me horribly sick and weak. Thought I had Covid or food poisoning so did not associate it with the medicine. Took it a few more times and had visual disturbances. Doctors had no idea what was happening and neither did I as my anxiety and crying was through the roof. My blood pressure was extremely low at night while I was sleeping. Checked myself into an inpatient because I thought I was going crazy. Developed a blood clot due to the medicine interactions and suffered a stroke. Ruined my life completely. This medication needs to be illegal. F 30 10 times
2 1X AN
6/21/2023
 1  Muscle Cramps severe Headaches I started taking this for leg pain/cramps related to Neuropathy. I started getting severe headaches a few hours after my first dose. It was so severe that it felt like a migraine along with nausea. As soon as I quit talking these and switched to Soma, the headaches subsided. F 34 3 weeks
4mg
8/28/2015
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 1  fibromyalgia/chronic pain I HATE this stuff! My Dr prescribed 4 mg but I can't stand the stuff, it knocks me out for an entire day if I take that dose. And either way, it does NOTHING for the pain or the spasms. I only take it so I can sleep, because I'm in terrible pain and my Dr refuses to believe me and give me actual pain meds! Run away from this awful drug! It makes me feel like I want to die. :( F 36 2 weeks
1-2 mg
1/1/2015
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 1  DDD/sciatica/backpain I felt all of my pain slowly melt away and fell asleep for 3 hours (as i expected) When i woke up later in the evening i felt like i did when i was younger and thought it would be fun to "day drink" so a little hungover/groggy. BUT i will NEVER take it again due to the extreme anxiety that began to hit me a few hours after waking, i feel so nervous and dizzy and im trying to talk myself out of it, it's just that the feeling of anxiousness is so strong. I threw the bottle away, I would rather be in pain than feel impending doom F 29 1 days
2 mg 1X day
1/27/2015
 1  Chronic migraine Insomnia, hypnic jerks I've always been a good sleeper but the second night on this pill I woke up 3 times with hypnic jerks - that falling feeling. Thought maybe it was just a "bad night" so I took a whole pill the third night. Nope....this med gives me insomnia. Will stop taking it. F 44 3 days
2 mg
5/1/2017
 1  Prescribed for sleep Blood pressure dropped VERY low, 71/49 F 60 3 months
4 mg
3/20/2018
 1  Muscle spasms due to Fibromyalgia. Worked briefly a couple times. Last 2 times caused agitation...buzzing and tingling in legs and arms. Funny sensation in neck and head...almost psychosis. F 52 5 days
2mg every
12/27/2016
 1  Hip pain I won't take this drug again. First, it only works for about 4-5 hours. I took it before bed. At first it makes you very tired, but about 5 hrs after falling asleep I woke up and felt very anxious. I could not get back to sleep. Both nights I took this I had the exact same experience of insomnia and anxiety. I also experienced extreme dry mouth and the day after taking this I felt nauseous and depressed. This drug was NOT worth the side effects and I only took TWO doses! Watch out for insomnia, anxiety, dry mouth and nausea. And be aware that this med is very short acting - it lasts only about 4 hrs. F 42 2 days
2 mg 1X day
5/26/2020
 1  At bedtime Awful! I took at night and the next am I couldn't walk, barely see, my Vision was so blurry. It took over 24 hrs to get back to normal. Seriously worst thing I ever took and when I tried to get up and walk the neck pain was so excruciating I thought I was going to die. Dumped it all in the toilet F 56 0 days
4-8mg 1X day
8/3/2020
 1  Muscle spasms in leg It worked for my muscle spasms but for several nights and days I started getting nausea. It started mild and now it is very bad, but no vomiting. I had cut back to 1 mg the last 2 nights. Before 9 pm the nausea was getting better. Two hours after taking 9 pm dose the nausea is worse. Worse than last night. I won't take it tomorrow night. F 69 2 weeks
1 to 2 mg 1X day
8/14/2020
 1  Shoulder injury I suffered a shoulder injury from dog yanking my arm to hard. Mri inflammation of tendons that attach to scapula. The pain was a 7 then with moving so much it became constant. Ice was the only thing that worked. Dr. Sends Zanaflex for spasms and tylenol #3 for pain. I started with 4 1/2 mg. In about 30 minutes I felt I needed to lie down. I felt like a mummy because I couldn't move. Fell asleep about 2 hours. The Zanaflex gave me confusion,also.I tried to talk to my room mate and wasn't making sense. It was like I was a zombie. I laid down most if the day to be safe. I didn't take another dose. It's been 24 hours and I still feel out if sorts. Do not take tiazidine/Zanaflex. Zanaflex should be prescribed with caution. This drug is mainly used for M.S. muscle spams by blocking signals in the brain. A shoulder injury flexiril would have been better. F 65 1 days
6mg 1X day
1/21/2021
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 1  Fibromyalgia Muscle Knots, cramps, Caused muscle cramps, knots and pain. Feel spaced out, disconnected. Severe headache, dizziness, dry sinus and mouth to the point of trouble breathing, ringing on ears,. Medication should not be prescribed or sold. Physicians need to stop giving this when all Fibromyalgia patients need is a very low dose of klonopin each day to stop the painfully tight muscles, twitches, muscle cramps, tinnitus, clenching teeth due to being in pain and to help a Fibro patient sleep better. (1/2 mg clonazapem 1-2x per day depending on weight). F 55 4 days
4 MG 1X day
4/18/2021
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 1  Muscle Spasms I tolerate medication very well and do not usually have a lot of side effects. This medication gave me the worst reaction I’ve ever had to anything. I started feeling quite dizzy and then completely lost my vision as I was walking. The next thing I knew I woke up on the hardwood floor with a knot on my head and my dogs next to me. I was alone at the time. What if I had been driving? I hadn’t reacted to it like that before, so I had no idea! I hadn’t taken it with any other new meds , I had eaten. There’s no explanation. I’ve never fainted before in my life. I have also taken several other muscle relaxers and not had any problems. I’m going to be very angry if this fall has damaged my recent cervical fusions. I recommend caution with this medication! It sounds like I’m not the only person that’s had serious side effects. Everyone has different experiences, but until you know how it affects you don’t drive and be careful. F 54 10 days
10 mg
11/8/2018
 1  Muscle spasms in neck and shoulders Severe worsening of neck pain and stiffness, I fell because of drop in blood pressure. Also have pressure headaches now, as if I wasn't miserable enough. How is this better than Soma? The only side effects from Soma are relaxed muscles and mild sedation. But the doctor disagrees.... F 36 3 days
4mg
2/11/2019
 1  Muscle spasms Severe, unbearable itching over entire body. Started first with tingling all over. When I stood the room was spinning because I was so dizzy. Doctor took me off flexeril, don't know why, that made me sleepy... would rather sleep than be so itchy! Would not recommend and will never use them again. My spasms can be severe and zanaflex did not help only caused the constant, unmanageable itching and dizziness. Did not sleep at all because of this. F 64 2 days
2mg 1X day
3/6/2020
 5  Back spasms Makes me dream more often. I think Zanaflex is the best muscle relaxer. Baclofen would be a close second. M 48 1 years
4MG 3X day
4/22/2016
 4  For chronic pain and spasms Only side effects that I have had are vivid dreams and drowsiness. This medicine works very well, but there is always room for improvement. Baclofen and Zanaflex are very comparable as in it's effectiveness. M 47 1 years
4MG 3X day
3/17/2016
 4  tight back muscles/disc herniation Tiredness, dry mouth, increased nighttime urination Would take again M 33 7 days
4mg 2X day
6/18/2019
 4  fibromyalgia; herniated discs; musc slurred speech but helped the most. my whole support group drove me off of it and now i have to take flexeril which i hate... THE BEST!!!! M 21 3 months
4 1X day
2/25/2010
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