ZANAFLEX Reviews (TIZANIDINE HYDROCHLORIDE)

Average Rating: 3.0 (125 Ratings)

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 ANTISPASMODICS ANTICHOLINERGICS

 Type: Rx Drug

  

ZANAFLEX  (TIZANIDINE HYDROCHLORIDE):  This medication is used to treat muscle spasms caused by certain conditions (such as multiple sclerosis, spinal cord injury). It works by helping to relax the muscles.   FDA Approval Date: 1996-11-27 (Sources: U.S. Centers for Medicare Services, FDA)

  

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Key to Ratings: 1=LOW (I would not recommend taking this medicine.)
5=HIGH (this medicine cured me or helped me a great deal.)

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More on ZANAFLEX: Reviews Summary  |  Drug Safety Information

RATING  REASONSIDE EFFECTS FOR ZANAFLEXCOMMENTSSEXAGEDURATION/
DOSAGE
DATE ADDED
 
 1  Muscle spasm Made me horribly sick and weak. Thought I had Covid or food poisoning so did not associate it with the medicine. Took it a few more times and had visual disturbances. Doctors had no idea what was happening and neither did I as my anxiety and crying was through the roof. My blood pressure was extremely low at night while I was sleeping. Checked myself into an inpatient because I thought I was going crazy. Developed a blood clot due to the medicine interactions and suffered a stroke. Ruined my life completely. This medication needs to be illegal. F 30 10 times
2 1X AN
6/21/2023
 1  Back pain nausea,dizziness,sore throat,muscle spasms, indigestion, severe anxiety,tinnitus,headache,chills.flu-like symptoms. Started out okay-slept a better but was constipated then the nausea,shaking and dizziness started around day 9-it got so bad I had to go to the emergency!I stopped the medication immediately but nearly a week later, I'm still getting all the side effects.It's worse after sleeping.These must be explained before taking the drug.I'm not taking it again F 60 10 days
2 mg 1X day
4/24/2023
 2  Migraine prevention Insomnia, anxiety, prickly skin sensations It didn't relax anything. I had insomnia and anxiety -me a headache . F 53 2 days
2mg 1X day
9/14/2022
 4  Low back pain Fall asleep within 30 to 45 minutes, and always take before bed. Find that I sweat really bad, but do not fully wake from that. Will wake about 4 to 5 hours after taking. Does help with pain. F 46 6 months
8 1X day
6/21/2022
 3  Thoracic injury Dry mouth. Dizzy. Severe itching. Seems to work well M 55 10 days
15 mg 2X day
5/12/2022
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 2  Muscle spasms Seemed to help with muscle spasms at night caused by spinal nerve injury in neck. After taking for nearly a year I had to stop because it caused tachycardia. F 50 1 years
1X day
3/2/2022
 2  Back surgery and cervical herniation Sweating at night and my blood pressure is been going up nightmares, muscle pain!! F 68 6 months
2 MG 2X day
1/11/2022
Email
 5  Migraine If I take with food it makes you fall asleep with in 30 min. So you better be in bed. Take on an empty stomach and you have about one hour before you fall asleep This med changed my life. Cured me of daily migraine. I read some of the reviews and I think doctors did not explain the drug well. If you wake up at 3 am. You’re on too high a dose. I take a benedryl with mine so I don’t wake up too early F 48 4 years
8mg 1X day
7/31/2021
Email
 1  Lower lumbar sprain Made me really tired. I would get up in the middle of the night to use bathroom. Then return to bed and sit down only to wake up and have no memory of making it to the bathroom or of what I just did. Scary to be walking around at night and have no memory of what you just did or how long you did it. M 64 4 days
4mg 3x a d 3X day
7/13/2021
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 3  Back pain I liked it at first, and only take 2 2mg tablets if my pain is severe in my lower back, and always before bedtime. It works great to get you to sleep, but by 3am, I spring awake, like, I am ready to go. In fact, I'm writing this at 330am, after taking this drug and I am so frustrated with the insomnia! If I take more, now, I won't be able to go to work in less than 3 hours, but I also can't sleep and my neck is hurting very badly. I didn't have neck pain when I went to sleep, but now it's severe. After months of taking this drug, this is how it always goes....take med, 1-2 before bedtime, then, wake up in 4-5 hours (extremely awake, can't go back to sleep), and cramped neck and shoulders with pain. My back spasms are minimized, as it says it will, but the side effects are becoming unbearable. F 42 13 months
2 mg 1X day
5/4/2021
Email
 1  Fibromyalgia Muscle Knots, cramps, Caused muscle cramps, knots and pain. Feel spaced out, disconnected. Severe headache, dizziness, dry sinus and mouth to the point of trouble breathing, ringing on ears,. Medication should not be prescribed or sold. Physicians need to stop giving this when all Fibromyalgia patients need is a very low dose of klonopin each day to stop the painfully tight muscles, twitches, muscle cramps, tinnitus, clenching teeth due to being in pain and to help a Fibro patient sleep better. (1/2 mg clonazapem 1-2x per day depending on weight). F 55 4 days
4 MG 1X day
4/18/2021
Email
 1  Muscle spasms, help with sleep Insomnia, anxiety, worsening pain in neck and shoulders Doctor prescribed Zanaflex to help with neck spasms and to help me sleep. Took 2 4mg tabs at bedtime. Made me drowsy at first but put my anxiety through the roof and had extreme insomnia. Took for second night and had the same reaction as well as my pain level also increased. Never taking this medication again! M 59 5 days
4mgx2 1X day
4/9/2021
Email
 5  muscle/joints/nerve pain Taking 2-4 mg every 2nd night for a debilitating muscle, joint and nerve pain from osteoarthritis, herniated discs, and general inflammation from multiple autoimmune conditions. Feeling slightly mentally slower the following day, however, I am getting my life back. It allows me to get restful sleep without waking up from pain and having to reposition multiple times. And in the morning my body feels good, I am able to get up and move like a normal person. Getting sleep and relief from pain allowed me to get back into low impact exercise and more active lifestyle which is medicine in itself. Besides tizanidine (Zanaflex) and ibuprofen, I am not taking anything else at this point. Was offered a spinal epidural, Lyrica, hydroxychloroquine, and also Botox for headaches and cervical dystonia. Tried CBD several times, and it was very helpful, however, each time it made me feel disabled and depressed the following day. F 50 30 days
2-4 mg 1X day
2/9/2021
 1  Shoulder injury I suffered a shoulder injury from dog yanking my arm to hard. Mri inflammation of tendons that attach to scapula. The pain was a 7 then with moving so much it became constant. Ice was the only thing that worked. Dr. Sends Zanaflex for spasms and tylenol #3 for pain. I started with 4 1/2 mg. In about 30 minutes I felt I needed to lie down. I felt like a mummy because I couldn't move. Fell asleep about 2 hours. The Zanaflex gave me confusion,also.I tried to talk to my room mate and wasn't making sense. It was like I was a zombie. I laid down most if the day to be safe. I didn't take another dose. It's been 24 hours and I still feel out if sorts. Do not take tiazidine/Zanaflex. Zanaflex should be prescribed with caution. This drug is mainly used for M.S. muscle spams by blocking signals in the brain. A shoulder injury flexiril would have been better. F 65 1 days
6mg 1X day
1/21/2021
Email
 1  After spinal fusion surgery Full body jerking. Could not sleep because I kept "jerking" violently about every 10 minutes. I had to put myself in a recliner to avoid hurting myself or possibly damaging the hardware in my back. M 44 3 days
3X day
12/5/2020
 3  Back pain Works wonders on back. Pain so much better. Knocks me out. Only bad thing is extremely vivid dreams every night.(sometimes bad). Wake up exhausted. Might try to stop taking. Just due to the dreams. F 61 4 days
1.5 1X day
9/30/2020
 1  Muscle spasms in leg It worked for my muscle spasms but for several nights and days I started getting nausea. It started mild and now it is very bad, but no vomiting. I had cut back to 1 mg the last 2 nights. Before 9 pm the nausea was getting better. Two hours after taking 9 pm dose the nausea is worse. Worse than last night. I won't take it tomorrow night. F 69 2 weeks
1 to 2 mg 1X day
8/14/2020
 1  At bedtime Awful! I took at night and the next am I couldn't walk, barely see, my Vision was so blurry. It took over 24 hrs to get back to normal. Seriously worst thing I ever took and when I tried to get up and walk the neck pain was so excruciating I thought I was going to die. Dumped it all in the toilet F 56 0 days
4-8mg 1X day
8/3/2020
 1  Hip pain I won't take this drug again. First, it only works for about 4-5 hours. I took it before bed. At first it makes you very tired, but about 5 hrs after falling asleep I woke up and felt very anxious. I could not get back to sleep. Both nights I took this I had the exact same experience of insomnia and anxiety. I also experienced extreme dry mouth and the day after taking this I felt nauseous and depressed. This drug was NOT worth the side effects and I only took TWO doses! Watch out for insomnia, anxiety, dry mouth and nausea. And be aware that this med is very short acting - it lasts only about 4 hrs. F 42 2 days
2 mg 1X day
5/26/2020
 2  Spasticity Extreme tiredness yet unable to sleep well. Vivid nightmare I have ms with disabling spasticity in my legs. I have to use forearm crutches to get around and lately I haven't been getting around much at all. The first 2 days I took the Tizanidine I thought it seems like it's helping a bit. The third day though It didn't seem to help much at all but made me feel so so tired and unmotivated. I don't normally feel unmotivated kind of feel like it put me in a bad mood. It could be in part from the lack of sleep. I did have a nightmare that I was dying and then when I awoke there was a baby crawling on my ceiling. That part wasn't really scary just weird. M 54 3 days
5/2/2020
  

ZANAFLEX  (TIZANIDINE HYDROCHLORIDE):  This medication is used to treat muscle spasms caused by certain conditions (such as multiple sclerosis, spinal cord injury). It works by helping to relax the muscles.   FDA Approval Date: 1996-11-27 (Sources: U.S. Centers for Medicare Services, FDA)

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