OSPHENA Reviews (OSPEMIFENE)

Average Rating: 2.9 (48 Ratings)

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 Type: Rx Drug

  

OSPHENA  (OSPEMIFENE):  This medication is used to treat painful sexual intercourse in women after menopause. Painful intercourse is a symptom of changes in and around your vagina, due to menopause. This drug is different from hormones (including estrogens and progestins). It works by acting like estrogen in some parts of the body. Ospemifene belongs to a class of drugs known as selective estrogen receptor modulators (SERM).   FDA Approval Date: 2013-02-26 (Sources: U.S. Centers for Medicare Services, FDA)

  

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Key to Ratings: 1=LOW (I would not recommend taking this medicine.)
5=HIGH (this medicine cured me or helped me a great deal.)

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  Charts & graphs: Drug Safety Information

RATING  REASONSIDE EFFECTS FOR OSPHENACOMMENTSSEXAGEDURATION/
DOSAGE
DATE ADDED
 
 4  vaginal dryness and pain I couldn't figure out where all this weight was coming from or fatigue. I started reading the reviews and this is the only addition to my daily routine. Its terrible. already 15 extra pounds in less than 3 months. I'm only 4'11" this is bad. The medication works great, but the weight is packing on. I'm not getting any younger, I'm single. I would like to meet someone. With that said, I need an alternative. My nipples were inverted . After taking Osphena, they stopped ! They don't do that anymore! The drug works for me. I also have had increase in headaches. Not sure if its Osphena. F 58 90 days
60 MG 1X day
7/28/2020
 4  Painful intercourse Works well for no pain. But I have gained 25 pounds. Not sure if its worth the weight gain. Very upset about weight gain F 59 6 months
60 mg
6/12/2020
 2  Dryness Weight gain- 5lbs in 10 days!! Dizziness Not worth the weight gaun 56 21 days
1xday
12/28/2019
 1  Vaginal dryness Horrible sweating day and night, trouble breathing, abdominal pain, leg cramps, fatigue. F 54 45 days
60 MG
12/18/2019
 1  Vag atrophy painful intercourse Irritating Vaginal discharge This product did not help at all. F 62 3 months
60 1x/day
12/12/2019
 2  Dryness Abdominal pain, hives F 57 2 days
30
11/21/2019
Email
 2  Dryness After 3 days of taking the medicine I had leg cramps and also started having lower abdominal pain. The pain would wake me during the night, like I was having contractions. I stopped taking the meds at 10 days. F 57 10 days
30 mg
11/18/2019
 3  Vaginal dryness and painful interco Weight gain and fatigue F 61 18 months
1x daily
11/15/2019
 3  Painful intercourse It helped at first but then stopped working , then came Dry throat, hoarseness and leg cramps at night that are so severe they wake me up yelling. No weight gain, lost 3 lbs. Abdominal bloating . I was never told by my GYN to only take this for a short time- I’m finished ! F 56 3 months
60 1X day
10/26/2019
 5  dysparenia 47 5 months
60
12/18/2018
 2  Vaginal dryness/painful intercourse I have always been thin, if anything underweight. I have been to several doctors to no avail. The only thing I haven’t changed is taking Osphena. Over the course of 3 years gained over 40 pounds! Why bother??? If I can’t even look at myself in the mirror who would want to have sex? Will go back to using lubricants as needed. Despite how hard I tried weight loss has been impossible! Will see what happens when I stop this drug. F 51 3 years
60
12/7/2017
 3  Painful Intercourse Weight Gain. I have been at a constant +/- 5 lbs for 25 years. I have now hit the + 5 and added 5 more. No eating or exercise changes. The benefits are not worth the side affects. The weight gain has made me lethargic and feeling down. F 55 14 days
1X day
10/9/2017
 3  Painful intercourse Increased appetite and weight gain Never had trouble with my weight. I exercise regularly but have not been able to bust through the muffin top gotten since I started taking osphena F 57 4 months
1 a day
9/18/2017
 4  Painful intercourse, vaginal drynes Weight gain; dizziness; hot flashes I was on Estrace before, which in addition to being messy didn't seem to work that well. While Osphena really worked for me, the side effects - especially the weight gain - will send me back to my doctor for an alternative. I haven't changed my diet and am in the gym 3 or 4 times a week. At this age I refuse to have to work even harder than I already am to keep my weight down. F 67 8 months
1X day
6/28/2017
 1  Dryness, painful intercourse, etc Weight gain with no change in diet, swelling of legs, feet,extremities, no increase in sexual interest,no help with painful intercourse, headaches, fatigue (extreme), still dryness issues, no resolution to anything and no help but additional issues instead Don't know why this is even marketed had tried the estrace and had allergic reaction as well as to its sister product with same natural ingredients. Itching and hives within days on them. 23 lb weight gain on this in 5 months and sweats are worse as is swelling, headaches, mood swings, fatigue, no marked aide in desire and no help with symptoms just additionnof others and hate the weight gain, sweats, (previously only night sweats, now sweats and chills frequently, swelling awful, seems I have memory issues as well, tired all the time. Very debilitating abdcas I saw reported by others... some abdominal pain as with female issues, etc. F 53 5 months
Daily
6/18/2017
 3  Painful Intercourse. Lower pelvic pain, extreme weight gain. I don't eat sweets, watch what I eat & excercise. I've never experience this much weight gain in such a short time. No more for me! F 55 1 days
10/10/2016
 1  Painful intercourse. Atrophy of vag 6 lb. weight gain which is virtually impossible to lose. Cramping of pelvic area and legs. Mood swings. Dark heavy discharge which caused severe irritation I have researched the side effects of this drug only after taking it. I wish that I had done so beforehand. I know now how it passed the approval of the FDA. Greed! F 64 1 months
30 mg
5/22/2016
 4  Dryness and UTIs I suspected weight gain may be a side effect. I've never had a weight issue before. I have developed a muffin top around my middle and I am exercising. Sure, I could be exercising more than I do and eating fewer sweets. It may not be the Osphena, but I'm not sure. I am happy with the results of the Osphena other than my recent weight gain. I will have to look closer at what I'm eating and step up my exercise a bit and see if that helps. F 53 90 days
60mg 1X day
5/16/2016
 5  UTIs and some dryness No side effects I had 3 UTIs in 5 months and some dryness even with lubricants. Since my doctor suggested trying osphena, I haven't had anymore UTIs, but I still use the lubricant. F 62 6 months
60mg 1X day
3/28/2016
 2   After a week taking Osphena, I started to experience abdominal pain and insomnia. However it did help somewhat my discomphort. After 10 days I noted also weight gain. I decided then to take it every other day. The abdominal pain went away but the pill not longer worked as previously. Now after a month, I am looking for other options with less side effects. F 61 1 months
1x D
3/16/2016

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