OSPHENA Reviews

Average Rating: 2.7 (41 Ratings)

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 Type: Rx Drug
  

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Key to Ratings: 1=LOW (I would not recommend taking this medicine.)
5=HIGH (this medicine cured me or helped me a great deal.)

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  Charts & graphs: Drug Safety Information

RATING  REASONSIDE EFFECTS FOR OSPHENACOMMENTSSEXAGEDURATION/
DOSAGE
DATE ADDED
 
 1  Vaginal dryness No weight gain , but leg and hand cramps, also my heart ejection fraction is 35!% (normal is 60-65) Took it 3 times per week F 60 12 months
60 mg 1X D
10/3/2021
 4  Vaginal dryness and burning Sweating. Terrible weight gain. Stomach bloating. Hot flashes. Cramped legs. Weakness in body. Foggy thinking. These side effects have emerged over time. It has just been recent that I have figured out it is the Osphena causing it. F 54 1 years
1X D
8/30/2021
 2  Dry vagina I eat prior to each tablet but it is wreaking havoc with my stomach. Heartburn, stomach pain, huge bloating of stomach. The stomach burn even after taking prescription antacids is the worse. This medication is useless to me if it, and it does, interferes with my daily life. It clearly states with sticker on box to take with food, so why is there not more info re upset stomach and diarrhea? F 69 10 days
60 1X D
8/16/2021
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 3  Vaginal dryness/painful intercourse Definitely got rid of vaginal dryness/atrophy and sex no longer painful, but excessive weight gain and no other benefits and really question long term safety. Now I'm on testosterone and what a total game changer. With Testosterone no vagina dryness, way increased libido, getting firmer fast with exercise, mental state so much better, and it's way safer. It has been used in other countries for a good while for women. Testosterone is the sex hormone in men and women. Women have the highest levels of testosterone when they are ovulating lol. When will American doctors get with the program. Thank goodness I have an enlightened gyn doctor! Would not recommend. I would recommend finding a doctor that understands how great testosterone is. F 61 20 months
60 mg 1X D
7/15/2021
 1  Vagina dryness and pain. Extreme weight gain, to my belly area. No changes to diet prior or after taking this. Also extreme sweating and headaches. F 67 0 days
60 1X D
6/14/2021
 4  Pain & constant UTIs I loved it but Ive gained 50 pounds in a year and Im fatigued all the time. I didnt think my weight gain was associated to osphena until I read this, as Ive been baffled. Im not sure of the trade off- constant pain or being fat and tired! It did stop my utis and sex was not painful. I also have vulvadynia and it has helped the constant pain from that. I see my dr on Friday and we will go over my first year on osphena. Maybe a lower dosage will help my weight gain. F 55 1 years
50 1X D
4/22/2021
 3  Pain & constant UTIs I loved it but Ive gained 50 pounds in a year and Im fatigued all the time. I didn’t think my weight gain was associated to osphena until I read this, as Ive been baffled. Im not sure of the trade off- constant pain or being fat and tired! It did stop my utis and sex was not painful. I also have vulvadynia and it has helped the constant pain from that. I see my dr on Friday and we will go over my first year on osphena. Maybe a lower dosage will help my weight gain. F 55 1 years
50 1X D
4/22/2021
 1  Vaginal dryness/ atrophy Rapid palpitations Some weight gain and fatigue F 65 4 years
1 1X D
12/29/2020
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 4  Vaginal dryness I wish I had not taken this medication. It worked fine, however; the weight gain is DEFINITELY NOT WORTH IT!! The weight came on so fast & I didn't know why. The only thing I was doing differently was taking this med. So I Googled the side effects & immediately stopped taking it when I read about the weight gain from others. I am still gaining with no major change to my diet and plenty of excercise. I now weigh 40 lbs more than I did when I started taking it. F 61 5 months
60 mg 1X D
12/7/2020
 5  Dryness Only feel flushed about an hour after taking Osphena This medication has helped me a lot the vaginal dryness was extremely bad and not just during intercourse it was all the time I could barely walk it was so bad, I tried Estrace and over the counter medication it never helped at all! I'm so thankful for my doctor recommended Osphena ! It gave me back my day to day life !!! F 57 4 years
60 1X D
11/28/2020
 5  Frequent UTI's 2 years, then stopped. Started again 3 mos. ago Was getting UTI's every 2 months and nothing helped until Osphena. It's a wonder drug for me F 73
60 mg 1X D
11/2/2020
 5  Vaginal dryness, painful intercours No side effects, but actually feel it has helped maintain weight. I lost 5 lbs from the flu right before beginning this medication and never regained it! I have loved keeping my ideal weight without having to struggle Osphena has been fantastic for me. It increased my estrogen from 40 to 112 in one year! F 58 1 years
60 mg 1X D
10/31/2020
 1  Painful intercourse Extreme weight gain, leg cramps that wake me up screaming and mood swings. Helped a little with the painful intercourse but not worth the trade off of bad side effects. F 53 6 months
60mg. 1X d 1X D
10/28/2020
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 4  vaginal dryness and pain I couldn't figure out where all this weight was coming from or fatigue. I started reading the reviews and this is the only addition to my daily routine. Its terrible. already 15 extra pounds in less than 3 months. I'm only 4'11" this is bad. The medication works great, but the weight is packing on. I'm not getting any younger, I'm single. I would like to meet someone. With that said, I need an alternative. My nipples were inverted . After taking Osphena, they stopped ! They don't do that anymore! The drug works for me. I also have had increase in headaches. Not sure if its Osphena. F 58 90 days
60 MG 1X D
7/28/2020
 4  Painful intercourse Works well for no pain. But I have gained 25 pounds. Not sure if its worth the weight gain. Very upset about weight gain F 59 6 months
60 mg
6/12/2020
 2  Dryness Weight gain- 5lbs in 10 days!! Dizziness Not worth the weight gaun 56 21 days
1xday
12/28/2019
 1  Vaginal dryness Horrible sweating day and night, trouble breathing, abdominal pain, leg cramps, fatigue. F 54 45 days
60 MG
12/18/2019
 1  Vag atrophy painful intercourse Irritating Vaginal discharge This product did not help at all. F 62 3 months
60 1x/day
12/12/2019
 2  Dryness Abdominal pain, hives F 57 2 days
30
11/21/2019
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 2  Dryness After 3 days of taking the medicine I had leg cramps and also started having lower abdominal pain. The pain would wake me during the night, like I was having contractions. I stopped taking the meds at 10 days. F 57 10 days
30 mg
11/18/2019
  

OSPHENA  (OSPEMIFENE):  This medication is used to treat painful sexual intercourse in women after menopause. Painful intercourse is a symptom of changes in and around your vagina, due to menopause. This drug is different from hormones (including estrogens and progestins). It works by acting like estrogen in some parts of the body. Ospemifene belongs to a class of drugs known as selective estrogen receptor modulators (SERM).   (Sources: U.S. Centers for Medicare Services, FDA)

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