DIFFERIN Reviews (ADAPALENE)

Average Rating: 3.0 (197 Ratings)

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 DERMATOLOGICS

 Type: Rx Drug

  

DIFFERIN  (ADAPALENE):  This medication is used to treat acne. It may decrease the number and severity of acne pimples and promote quick healing of pimples that do develop. Adapalene belongs to a class of medications called retinoids. It works by affecting the growth of cells and decreasing swelling and inflammation.   FDA Approval Date: 1996-05-31 (Sources: U.S. Centers for Medicare Services, FDA)

  

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Key to Ratings: 1=LOW (I would not recommend taking this medicine.)
5=HIGH (this medicine cured me or helped me a great deal.)

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More on DIFFERIN: Reviews Summary  |  Drug Safety Information

RATING  REASONSIDE EFFECTS FOR DIFFERINCOMMENTSSEXAGEDURATION/
DOSAGE
DATE ADDED
 
 4  mild acne small bumps dryness, very itchy, skin peeling, painful around eyes b/c accidentally applied (be careful to avoid eyes!), symptoms are better with time, must apply lots of moisturizer One month into treatment, taking Differin at night and Duac in the morning, worse in first 2-3 weeks before it starts getting better, but sticking to the program. Wash w/ Cetaphil cleanser at night before Differin and apply Cetaphil moisturizer every morning after Duac. Just now I am starting to see my skin clear and small red bumps fade and disappear. Some days small pimples show up but overall medication is working. Would recommend but must show patience. F 23 1 days
4/3/2007
 5  Acne No side effects. Took several months to see skin improve. F 28 6 months
3/26/2007
 1  Bad acne Tons more acne than what i started with, first week i got alot alot more, 2nd and 3rd week it started to dissapear almost fully, on the 4th week i gained alot alot more acne, and it just keeps coming in. Very oily, red, very very very bad product, makes you want to hide more than you ever have. Horrible product, doesn't treat acne at all, just increases! DO NOT USE M 16 4 weeks
3/18/2007
 2  acne dryness, peeling, burning, wrinkles, very deep scars - and I don't use a lot. I take differin at night and duac in the morning. The doc said I can wear makeup - yeah right. makeup is a mess because it is a flaky, clumpy mess and it burns. I also have new wrinkles. I'm not sure which one is the culprit-the differin or the duac. Also, I've never scarred from acne until after using these creams. They are deep scars, too. The acne has improved, but not enough to account for all the scars and wrinkles. F 27 5 weeks
3/17/2007
 2  Acne worse acne I was using this at night, while using Duac in the morning. I'm not sure if it was both of these creams that damaged my face, or if it was just one of them. The derm said I would have an initial breakout but then it would get better. I didn't know it was gonna be THIS BAD. You literally could not see my face. I continued to break out severely for a few months after stopping these medicines, and after only 3 months, my entire face is A SCAR, looking like it took years for the scars to build up. F 17 3 weeks
2/6/2007
 1   SPOLTCHY ITCHY RASH!!! i dont reccomend to those with minor achne F 15 2 weeks
1/29/2007
 4  Pretty Bad Acne None really. My skin may have been slightly red at first and a bit dry. But now.. my skin has cleared up.. obviously not 100% yet but i dont get as many pimples.. all i have are scars from before (even those are starting to become less red) and maybe tiny tiny pimples that come up occasinoaly but disappear within like two days! Try it.. i started it once but stopped cuz i dint think it worked.. I TRIED IT AGAIN.. properly.. and it did! F 18 1.5 months
12/19/2006
 1  in preperation for my wedding I went on Erythramicin(to prevent cyst breakouts I get when stressed) and was perscribed Differin to prevent any topical break outs. I got the perscription and started using 2.5 months before my wedding. HORRIBLE results. My skin is a mess. Red marks, deep black heads, it is terrible. After 2 years of being off of Proacive, then using Cetaphil and Benzoil Peroxide...these both worked, but started to loose their effect. I thought this was the miracle I was waiting for. I just went back to Proactive, and am hoping my skin will clear up in the 12 days I have before I get married! At this point makeup makes it look worse! I had the cream. It made my skin like an oil slick. F 27 2 months
11/27/2006
 3  Acne and acne scar Firstly,my dematologist doing the chemical peeling for me... but..second procedure,she ask me to keep on using the differin up to six months... now stil using this product... I think is good for acne but about the scar I think it doesn't work well..... hope it can really clear my pesking ACNE...... and my scar,hopefully can heal faster... M 20 4 months
11/25/2006
 3  acne none I saw a bit of improvement, but not much F 39 1 years
11/16/2006
 3  mild acne none i am interested to see if this clears up my acne on my jawline and neck. my skin feels smoother but i still have red bumps and a few pimples on my chin. i think it may take a couple of weeks to get the redness out. i am also on minocycline 100mg F 29 5 days
10/20/2006
 1  Almost but Not Quite Severe Acne My pimples hurt, got even more enflamed, and scarred. I used to have bad acne, but it was getting better, and when I started taking Differin it brought back all my pimples, I got ever more than before, they all scarred, and I have holes in my face now. It's been about 8 weeks and this is one of the worst medications I've gotten ever in my whole life. F 8 weeks
10/8/2006
 5  Adult Cystic Acne NONE I looove this product! It's the only thing that's ever kept my skin clear!!! F 28 4 years
9/19/2006
 2  under the skin lumps and mild acne really didn't experience any side effects -- found it very easy on my skin when compared to other products used to date. I really hate differin. My skin was looking great except for some small under the skin white lumps (keratin?) which is when my derm perscibed it. Instead of taking care of the lumps, it took me back about 4 years and brought back all of the acne I had finally gotten rid of! I've given up using it because I'm not patient enough to wait 6-8 to see improvement plus I'm not convinced it will work for me. F 19 3.5 weeks
8/2/2006
 1  mild adult acne, blackheads burning,extra pimples took in combo with something called zoederm and broke out worse than ever. Doc told me it would get worse before better but at 2 mo. just still getting worse, embarassed 2 b seen at this point and makeup can't hide it. F 23 2 months
6/18/2006
 5  mild acne I've used this product probably for 4 or more years on my chin and nose. Initially I had dryness, redness as if sunburned. But nothing unmanagable. Recently I started using it on my chest as well, and it has caused extremely itchy, scaly, red skin. I'm hoping that will subside soon. On my face, it has worked like a charm. I almost never ever get the big, deep, painful pimples I used to get on my chin. I love it! And I've used it for years on my face. Still waiting for results on my chest. F 37 4 years
6/3/2006
 5  adult acne First week--very irritated, scaley, red, and sensitive to touch. I took a day off here and there. Now at the end of 3 weeks, side effects have nearly disappeared. Worth $104.00? I'm pretty sure I've spent at least that much in the past year on makeup and over-the-counter treatments that didn't work or made my acne worse. I took Accutane in my early 20s and it worked great, but the risks and side effects are too high now that I'm wiser. This is the next best thing. My doctor told me there was a generic available, but there isn't! When my pharmacist told me the total, I almost fainted, especially because I'd have to tell my husband how much it was. He, too, almost fainted, but he's seen the difference it has made to my face and my confidence. So it's worth it. F 30 21 days
5/29/2006
 4  acne none at all I found out that sequential approach works. I applied gel for 2 nights for two weeks and then i added one night extra for every two weeks,i.e. twice weekly for 2 weeks,3 times weekly/2 weeks, 5 times/2 weeks,6 times/2 weeks and every day. And it worked great. No peeling, no dryness, no stinging. There was no burst of acne all at once but it came gradually, lasted for few days and disappeared. Scars from previous acne had diminished.I also tried azelaic acid which worked fine as well. M 25 2 months
5/3/2006
 3  Acne Dryness EXPENSIVE! F 16 30 days
4/29/2006
 5  Moderate Acne First week or so I had slight dryness, a little redness. Acne got a little worse after a couple weeks, but it was tolerable I only use Differin now, was using Plexion topical and Tetracycline as well at first, stopped those after 3 months. My skin is 100% clear. Acne scars are gone at this point. Just deal with the dryness and extra breakouts at first as your skin reponds to the medicine, it doesn't last long. It does work if you use it PROPERLY and stick with the program. F 28 1 years
2/16/2006

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