DIFFERIN Reviews (ADAPALENE)

Average Rating: 3.0 (197 Ratings)

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 DERMATOLOGICS

 Type: Rx Drug

  

DIFFERIN  (ADAPALENE):  This medication is used to treat acne. It may decrease the number and severity of acne pimples and promote quick healing of pimples that do develop. Adapalene belongs to a class of medications called retinoids. It works by affecting the growth of cells and decreasing swelling and inflammation.   FDA Approval Date: 1996-05-31 (Sources: U.S. Centers for Medicare Services, FDA)

  

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Key to Ratings: 1=LOW (I would not recommend taking this medicine.)
5=HIGH (this medicine cured me or helped me a great deal.)

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More on DIFFERIN: Reviews Summary  |  Drug Safety Information

RATING  REASONSIDE EFFECTS FOR DIFFERINCOMMENTSSEXAGEDURATION/
DOSAGE
DATE ADDED
 
 3  clear acne The first days i started it cleared some of my acne great, but then by week 2 my skin became red, flaky and dry in some places( I have combination skin) Im gonna keep doing this because i really hope it works. F 14 2 weeks
2/2/2010
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 3  acne its ok i can't say i've used alot of acne treatments i've prolly used 5 & differin is the best soo far but not by much i've been using for a while now like over a year and it did clear my skin a lot n it looks better than it did but it has never been fully gone and it leaves my skin with a lot of dryness F 15 1 years
1/3/2010
 3  teen acne burning, itchiness, redness Hoping that the pain is worth it. F 16 6 days
1/3/2010
 3  adult acne I just started using this medication. Day 2 i have very dry skin, face hurts,peeling skin, skin is tight when smiling, and i have some swelling and redness around my eyes. So far im not sold because it feels like torture....but i will continue to apply in hopes that it works. M 24 3 days
1/2/2010
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 2  acne drying skin. NEVER cleared my acne. I think it actually got worse. F 30 3 months
1/1/2010
 3  adult acne burning, redness in the cheeks, flaky skin only on my 5th day....im hoping after reading others comments, this will all be worth it... F 30 5 days
12/16/2009
 4  Teenage Acne Inflammation, Flaking, Dryness Over the last 4 years or so dealing with acne I've tried many prescriptions. Many of which either relieved my acne on a short-term basis or simply none at all. My dermatologist prescribed me differin. As a tip, follow the instructions except for one thing: it is not necessary for you to apply 3-4 pea size drops as it mentions. You only need enough to cover "affected" areas. For me it's one and a half pea size. Combined with a moisturizer such as cetaphil is highly recommended otherwise you can expect excessive dryness and a lot of flaking during the next few days. Dryness and flakes gradually reduce over the course of usage. I apply differin every three days or so ever since I had experiences similar to another user in regards to swollen eyes. Keep it as much as away from the eyes, that includes washing your eyes after applying as you might scratch your eyes or something while sleeping. When my skin started burning I stopped and waited until most of it subsidized and I reapply. Also apply a layer of 30fps sunscreen as any long periods of sun/light source exposure can further make your skin burn. Overall, your skin will get better. I've seen major improvement and there are areas of my skin where it has become smooth. Patience is the key to differin. M 18 2 months
12/1/2009
 2  adult acne-chin and cheeks. The first two weeks were hell. Couldn't even touch my face or apply make up.My skin was tight and sore and my eyes looked weird! I reduced to putting it on once every three days and then built up to daily use relatively quickly. Apply a very thin layer. Less is more with this cream. It hasn't made any difference to my skin so far...I still find the creases at the side of my eyes are really sore even though i dont put the cream there at all. Seem to have extra wrinkles around the eyes. Due for a review in january. Dont expect the dermatologist to continue with it. It's not working for me at all. F 27 4 months
11/22/2009
 1  Bad teenage acne burning, flaking of the skin, tightness, itching I've only been using it for a couple of days, i'd rather have acne! F 13 2 days
11/2/2009
 3  severe acne burning, irritation, peeling i've only been on differin @ nite and duac in the am; also solodyn antibiotic. the combo has worked well so far. i've been told you have to be patient with differin. i had to change my moisturizer from purpose to cetaphil. for some reason the purpose doesnt work well with the gels, it leaves residue. i hope it gets better with time. acne is by far the most embarrasing thing to have ever! F 25 2 weeks
10/27/2009
 3  Adult Acne Terrible first two weeks. Peeling and redness and breakouts I have been on this for a month. The redness and peeling has gone away and my skin does have somewhat of a smoother texture. But I have like 3 large cysts that appeared recently, which I have never gotten before! I really hope these go away or else I will have to stop this! Did anyone else have this problem? F 25 1 months
10/22/2009
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 5  adult acne dry skin, sensitivity to lotions and sunscreens Initially there was a lot of drying, redness and a few breakouts, but my doctor told me to be patient and keep using it, even though it might look worse before it got better. I'm glad I did, because my skin is 100% clear and I can go out without makeup and still receive compliments, which makes me feel very confident. During the first 3 months I would get one or two very deep, very tenacious pimples that have left red marks, but the red marks are slowly fading. I was prescribed a combo of Differin and Metrogel, which seems to be helping to fade redness and old acne marks. I noticed that I get a build-up of dry, rough skin depending on how much I apply - too much and my skin gets flaky - so really use Differin sparingly and it will help with the dryness. F 29 5 months
10/13/2009
 5  Hormonal Acne/blackheads Minimal peeling around nasal area the first week. Face stings slightly when heavy sweating. Derm prescribed Differin 0.3 gel with Aldactone and Benzoil peroxide for horomal acne and blackheads. Wow! was I impressed with Differin. I saw immediate results in removing blackhead on my nose. My skin is more evened out and I am more comfortable going in public without foundation. Also is removing fine lines and brown spots. Will be part of my routine from here on out. Since being on all 3 of these meds, my face is sensitive to sunlight and sweating. But, no big deal, doesn't stop me from being in the sun (use more sunscreen) or from working out. F 41 30 days
9/20/2009
 1  hormonal cystic acne The day after applying Differin for the first time, I experienced flushing and burning, similar to a mild sunburn all over my face. By that night, my face was completely covered with miniscule water blisters that began spreading down my neck and chest, even though I only applied a pea-sized amount of Differin to my face. My face then began to swell, with fine wrinkles appearing around my eyes and mouth, and my face is now burning fiercely. I am also experiencing the formation of some pimples, but the pimples are nothing compared to the water blisters. Due to the water blisters that were not listed as a side effect on the medicine label, I have not applied any more Differin to my face, although I was supposed to use it twice weekly. It has been almost a week since I first applied Differin, and my symptoms are getting worse, rather than improving. I am, of course, still waiting for the phone nurse from my dermatologist to return my calls regarding what I should do. Regardless of whether or not your dermatologist believes you can use this product, if you have sensitive skin, a fair complexion, and/or mild acne, I would strongly recommend that you do thorough research about Differin and only do a small spot test to begin treatment. I am sure this product works well for some people, but like any medication, there are always exceptions. I would much rather suffer from acne than use this product again, which is a strong statement, as cystic acne is excruciatingly painful. Please exercise caution when considering the use of this product. F 25 5 days
7/22/2009
 1  acne / perioral dermititis SEVERE BURN , scaly tight skin, can not hardly bare to open my mouth wide because it pulls my skin tight around my lips, i am miserable M 26 4 days
7/14/2009
 2  Mild/Moderate Acne I have been taking it for several weeks. I noticed a clearing of pimples after a day of use. It did get rid of whiteheads, but I still have all of my blackheads and I have noticed an increase of many small red bumps that don't come to a head. After a few days, I put on Jergen's gradual tanner on my face (after Differin) and I felt the worst pain I have ever felt on my face. I stopped using the product, and several days later my face peeled like crazy and was red and painful. My nose was extremely oily while my cheeks burned and peeled. It still hasn't gone away. I am stopping my treatment with Differin now. F 16 3 weeks
7/3/2009
 5  hormonal acne In the beginning dryness aroung chin area and increased breakouts. After 9 months my skin looks great! It also helps fade minor acne scars. Don't pay any attention to people's comments about drying skin and breakouts. That is what is supposed to do! After awhile this goes away your skin will adjust and you'll be left with flawless skin. BE PATIENT!!! Most of those comments are from people using it less than a month. It does work! Trust me. Just use a light moisturizer before applying any makeup or toss the makeup and use a light powder (not mineral powder.. it clogs pores) and don't go in the sun with out SPF 30 on your face or you'll be sorry. F 39 9 months
4/26/2009
 3  Mild acne, hormonal breakouts Peeling, dry skin, flaking, eye swelling KEEP THIS AWAY FROM YOUR EYES. I can't stress this enough. It says so on the package and in the drug information. I had been using it for about a year and one morning woke up with my eyes completely swollen shut. After visiting with 5 different doctors and and allergist we figured out it was the differin, I can't put it anywhere even close to my eyes without developing serious swelling. However for acne, it works well, especially as a spot treatment with mild breakouts. F 24 1 years
4/24/2009
 5  adult acne redness, peeling and itchy I have only been using drug for one week but have seen some visible results already. My dermo reccomended mixing pea size amount with a little facial moisturizer (I use purpose) This prevents it from drying so much. I have been impressed by this product. I would reccomend not using Foundation while using the product. Your skin will heal more quickly. I go back for a followup in 11 weeks and hopefully if the results keep going the way they have in such I short time I will be thrilled. F 31 7 days
4/7/2009
 1  Teenage Genetic Acne Burning, Itching, Red Splotches all over my face, Tightness, Extremely flaky skin, Ultra-Sensitivity I'm about into my second week with Differin, and all 14 days have been hell. I had tried just about everything over and under the counter for acne, and I had hoped that Differin would be my miracle drug. Now I just wish I had never used it! Trying to put on makeup's a joke, because it just all clumps and flakes all of the dead skin into massive bits that are impossible to peel off. Using any soap or water or moisturizer after you've used this feels like your face is on fire, and the itching is unbearable. I'm a 13 year old girl with enough image problems as it is. I didn't need this too! Just please don't even try this product. It destroys your skin, and makes you look ridiculous. F 13 14 days
2/18/2009

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