DIFFERIN Reviews (ADAPALENE)

Average Rating: 3.0 (197 Ratings)

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 DERMATOLOGICS

 Type: Rx Drug

  

DIFFERIN  (ADAPALENE):  This medication is used to treat acne. It may decrease the number and severity of acne pimples and promote quick healing of pimples that do develop. Adapalene belongs to a class of medications called retinoids. It works by affecting the growth of cells and decreasing swelling and inflammation.   FDA Approval Date: 1996-05-31 (Sources: U.S. Centers for Medicare Services, FDA)

  

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Key to Ratings: 1=LOW (I would not recommend taking this medicine.)
5=HIGH (this medicine cured me or helped me a great deal.)

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More on DIFFERIN: Reviews Summary  |  Drug Safety Information

RATING  REASONSIDE EFFECTS FOR DIFFERINCOMMENTSSEXAGEDURATION/
DOSAGE
DATE ADDED
 
 3  moderate acne redness, burning, scaling, extremely dry skin, and a few new deep breakouts There was very painful dryness and my entire face looked sunburned. I have had scaling around the scrap/hair line. After a week the redness has began to subside, but still very dry skin. Moisturizer has seemed to help, but only minimally. I have seen a few new break outs in areas I don't normally get them, but my problem area (chin and neck) seem to be progressively getting better. I started out with twice a day, but needed to reduce it to 1x per a day because the burning was severe. M 26 2 weeks
1X day
12/8/2010
 4  Severe Acne For the first 2 weeks I had really painful, dry, and itchy skin. Afterwards it went away but redness didn't go away for about 2 months or so. It has REALLY helped, I recommend this because it's a topical that actually gets rid of the acne instead of temporarily making it disappear. I do admit, though, that it does take a while- I'm halfway into my fourth month and I have very little acne but it's close to going away. I visited my dermatologist last week and she said I was doing really well; I still have about another 6 months until I can go off of Differin but other than that I'm really happy that it's actually doing something. Looking at my pictures from several months ago I see that it really has made a difference, although I couldn't tell before (since it took so long). M 17 4 months
45g 1X day
11/23/2010
 2  Acne problems First I begin with 10 MG, my skin was not affected by Defferin. After 6 days I tried with 20 MG, and the last 5 days with 40 MG - the result was awful dry skin. After the 14th day I was with no pimple but with "sored" face. My choice now is Fitoderm. It's good because treats the acne inside to outside - the right way. http://helpingwithacne.blogspot.com/2010/09/fitoderm-review.html M 28 14 days
10-20 MG 2X day
11/4/2010
 2  acne Puffy eyes and the skin around my eyes is itchy and dry. The skin has so many wrinles around my eyes now. I feel like an old lady. I stopped using it and it's been over a month and my eyes continue to flair up. At this point I have to stop using eye creams as well or anything else on my face to see if I can get rid of this condition. F 39 21 days
daily 1X day
10/25/2010
 4  mild acne and brown spots drying and flaking of skin I was not happy at first, due to the drying and sudden appearance of lines around my eyes. After reading the comments by other readers I realized this is the product working well. I have begun to use a stronger moisturizer for dry skin and that helps. I have noticed that several of the brown spots have already begun to fade! I hope the pronounced wrinkles are just the "snake skin" getting ready to peel and reveal younger looking skin! F 42 16 days
.3% 1X day
10/22/2010
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 1  Severe Teenage Acne Extreme dryness, extreme itching, Sun sensitivity, red patches all over my arms, redness of the neck, burning, prickling. This medicine is horrible, never take it. When I was about 11, I started developing severe acne on my forehead, cheeks,chin, forehead and back. They where large, painful cysts. I went to the derm after about a year and she has done nothing but torture me, the whole visit she tried to sell me acne pills that you have to take a pregnancy test to be on (nothing doing!!) and told me that my acne was horrible!! She perscribed Differin and the first couple of months it worked pretty well, it got rid of the painful cysts and a lot of the redness, but then the side affects hit. They are even worse than the acne was, I have to put on lotion and sunscreen 2 or 3 times a day to avoid killing my self for the itching on my upper arms and neck,if I get the lest little bit upset, that makes it itch too, and if I sweat, it burns like crap plus all the other effects I listed above. I am currently not taking it and praying that my acne won't come back.I'm going to make and appointment with ANOTHER derm and get perscribed something different. Please, for your own sake, if your doctor ever wants to put you on this medicine,say no and get something else, you'd probably rather have the acne.I hope I helped someone. F 13 5 months
Peasized 1X day
10/20/2010
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 5  acne some dry skin for the first 2 months of using this my skin was a little improved but i kept having at least 2 cystic pimples at all times, and then after almost exactly 8 weeks my skin completely cleared up and i have not had a single pimple. i don't have to wear any makeup and have never had such clear skin. so even though it took a while for me to have such amazing results, it was well worth the wait! i love my skin! F 19 2.5 months
1X day
8/19/2010
 2  Acne Mild flaking Hasn't worked for me after 30 days and as most people will attest to has actually made the situation worse. Will continue patiently for another 30 days and repost results. M 34 30 days
1X day
6/18/2010
 4  moderate to severe acne I am on Differin for the second time in my life. Had to stop taking it before because I did not have insurance. This product initially causes flakiness and sensitivity but it gets better the more you use it. You can start by using it every other day or so and use it nightly after your skin gets used to it. My doctor specifically said only a pea sized amount and only at night. The sun makes the medicine ineffective so if you are putting it on in the morning, you are wasting your time! Also you MUST wear sunscreen with this product - it makes you very sensitive to the sun. My doctor also told me that when you apply it, the differin spreads itself once your skin absorbs it. so AVOID ANY AREA BY YOUR EYES! you have to account for the medicine spreading to this area on its own so be careful! Differin changes the direction in which your skin grows, so it is less likely to be clogged by dirt and oil. It is a prevention medicine that only works while you continue to use it! F 27 6 days
.03% 1X day
6/1/2010
 1  adult acne severe cysts, red marks Had very mild acne after stopping Yasmin. Derm gave me Differin - worst thing I could have done. Used it for a week; my face hasn't broken out like this since I was 14. I've been off it for a week and am hoping these cysts clear up soon. F 29 7 days
.1% lotion 1X day
5/15/2010
 3  Teen Acne Redness, Dryness, Mild Irritation At first it made my face so dry that my skin cracked and peeled when I smiled. Eventually I couldn't even find a pimple on my face. Just recently I broke out again, but this time the Differin hasn't helped. I'm not sure why it just stopped working. I have been changing up how much I use and how often, and I find that I get the best results putting only a thin layer on and taking a break from the medicine every 6 or 7 days. Hope this helps someone. M 17 1 years
1X day
4/26/2010
 5  mild acne I have recently started using Differin and have had amazing results. My skin has completely cleared up, and I don't need to wear makeup. The only bad experience I had was after using it a few days I had a facial and the products used did not react well with the Differin, causing very red sore skin which took about 4-5 days to heal. You need to be very careful about what other products you use at the same time. F 29 1 months
1X day
4/22/2010
 5  Severe Teen Acne Breakouts first few weeks I used Differin last year and it completely changed me!the first few weeks i had a few white heads popping out here and there but after that it was just getting clearer and clearer week by week. I stopped using it in August(may right now) and my acne slowly came back because I irritated my skin while shaving to much and started takin protein which made my hormones crazy and caused me to break out. Now my acne is SEVERE. I used retin-a for a week n almost cried when i put my face on a pillow because it hurt so bad!The first 3 days of using Differin once again my face felt like a face again and not an open wound. The flaking came n went and now my face is slowly seeing better results. M 17 1 years
1X day
4/20/2010
 3  adult acne redness, tenderness, photsensitivity My dermatologist said it could be used for wrinkles, so I applied very small amount around eyes, ouch I will never do this again, It caused red small cuts on wrinkles, and hurt like crazy. Ill live with the wrinkles F 38 7 days
150 1X day
4/7/2010
 4  mild breakouts/ mild teen acne redness for about 1st week it is the best thing i have ever tried in my life and the only acne medication i can trust with my skin F 16 2 years
1X day
4/2/2010
 4  adult acne The 1st couple of days my face was really dry and I had some peeling. I also had a burning sensation around my chin and upper lip area, but that subsided after a couple of days. It has been a couple of weeks now since I began using Differin and I love it ! It has really cleared up my skin. Co-workers and family noticed the difference in my skin in the 1st week. I would like to note that I did not have severe acne but would break out constantly, especially around my cheeks & chin. I am going to continue using it and would definately recommend it to others to try ! F 36 2 weeks
1X day
4/1/2010
Email
 4  Clogged pores and Forehead Acne Dryness around mouth and cheeks. Slight redness. It has cleaned up my clogged pores nicely and keeps them clean which is equaling less breakouts. Cleared up forehead acne within first week. I'm impressed to say the least! I will continue to use this in conjunction with Cetaphil Cleanser and a Micro fiber wash cloth. F 30 15 days
.01% 1X day
3/30/2010
Email
 4  adult acne; hormonal acne Dryness and burning, appeared to age overnight especially around the eyes The first week I had severe burning then dryness and peeling. My eyes appeared to age overnight. However, the peeling is revealing newer skin with smaller pores and a glow I have not had in years. The product dries out the skin's upper layers as it is supposed to. The aging appearance is your skin drying out like a layer shedding snake skin (a little embellishing) that needs to shed to reveal the new skin. If you can endure the burn torture it is well worth the youthful look you get in a week or two, if you are over 35. If you are younger you might want to try something else. As for the acne, mine did get worse over the first 1-2 weeks but dried out and is now healing. I am on week 2 still. I think it shows promise but Differin def has a price to get you where you want to go. Oh, just a good laugh for you: I was chopping chiles the other day and rubbed my cheeks on accident. Now that together with the 3rd day on Differin and my face was red like a sunburn and wow did it hurt. I guess the days following that were nothing compared. I did use this product years ago in my early 30s for spot treatment during PMS. It worked really good. When I was pregnant at 34 I stopped, as you have to. It really did not get bad enough to retry meds until now. F 38 14 days
.3% 1X day
3/5/2010
 5  teen acne if used to much it would leave a residue-not all bout be asorbed. mild dry skin Personally i had really bad acne but after useing Differin along with Yaz my skin compltely cleared up. i never thought i would have smooth skin but now thanks to Differin i do F 15 1 years
45 g 1X day
2/8/2010
 3  mild acne, skin discoloration extremely swollen eyes!!! Red burning circle around my eyes I use a pea sized amount,twice a week, only on effected areas, nowhere near my eyes and when I woke up on morning my eyes were like two massive puffs.Red, itchy, painful. Swelling lasted 1 week,I am unrecognizable. F 29 14 days
2/3/2010
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