DIFFERIN Reviews (ADAPALENE)

Average Rating: 3.0 (197 Ratings)

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 DERMATOLOGICS

 Type: Rx Drug

  

DIFFERIN  (ADAPALENE):  This medication is used to treat acne. It may decrease the number and severity of acne pimples and promote quick healing of pimples that do develop. Adapalene belongs to a class of medications called retinoids. It works by affecting the growth of cells and decreasing swelling and inflammation.   FDA Approval Date: 1996-05-31 (Sources: U.S. Centers for Medicare Services, FDA)

  

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Key to Ratings: 1=LOW (I would not recommend taking this medicine.)
5=HIGH (this medicine cured me or helped me a great deal.)

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More on DIFFERIN: Reviews Summary  |  Drug Safety Information

RATING  REASONSIDE EFFECTS FOR DIFFERINCOMMENTSSEXAGEDURATION/
DOSAGE
DATE ADDED
 
 5  moderate adult acne very mild dryness I had perfect babybutt smooth skin until about 23 yrs old, I began seeing a dermatologist after about a year of suffering and my acne was scarring my face. I can't remember over the course of ten years all the RX and OTC's I tried and went to aprox. five different dr's. I even did a round of accutane which made my moderate acne so much worse , I began getting cystic acne sometimes with cysts the size of a plum. At 33 I went to a new dermatologist this was my first visit in five years after the accutane nightmare, I was skeptical but wanted to try one more time, She prescribed Differin gel.I applied a pea sized amount every nite and a moisterizer, I didn't notice any changes for weeks, after about a month or so I was still breaking out but also noticed some small hard whiteheads . Around the four month mark BAM! perfect skin ,no zits, blackheads or whiteheads after six months my acne scars were nearly gone. From that time on it just got better my face looked perfect . unfortunately I can't afford it anymore,after stopping use for a year and ahalf my skin stayed clear for about two years and then the acne returned , I still don't have insurance (it's been about four years) and when I do have the ability the first thing i'm doing is getting an RX for differin again . F 40 18 months
3% 1X day
1/1/2012
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 4  Acne, scarring from folliculitis Burning, scaly, itching, dryness, sensitivity to light. I've been using retinoids since I was 13. The retinoids today have less side effects if used correctly. There is less scaling and burning if you wait 20 minutes to apply after washing your face. Mix only a pea sized amount to a moisturizer and apply. There will be side effects for the first few weeks and results may not appear for 1-3 months. Be patient and DO NOT use too much. Differin helps clear acne, fade acne scars and even improve the appearance of scars over time. F 35 30 days
1X day
1/1/2012
 3  Mild acne and small cyst Mild, passing burning, particularly around the eyes. Mostly went away when I increased avoidance of the eye area. Some mornings after applying it I will wake up with very oily skin, but it wipes off easily. Caused some mild flaking when I used it in combination with my make-up which contains salicylic acid. I have seen a marked improvement in my mild acne, but so far have seen little to no change in the small cyst on my face which is what it was primarily prescribed for. However, I haven't been using it for long. F 29 10 days
1X day
11/21/2011
 1   Extreme burning! Where ever I used the differing gel my face completely peeled; it felt like a constant sun burn. It was sore to touch and it hurt even if I didn't touch my face. this product is so something I will never use again. F 19
1X day
10/23/2011
 4  Hormonal Cystic Acne, Blackheads I have very sensitive, oily skin. At first, my skin looked horrible, but once the top layer started flaking off, things got better. Now I can put it on my forehead, nose and chin without irritation. I have dermatitis on my cheeks and above my eyes, and I have constant flare ups, so unfortunately I have to avoid those areas of my face. However, I am able to use it where the acne is (my T-zone & chin) so I'm happy with it. So far I can tell it's working on clearing up those stubborn blackheads that I haven't been able to get rid of since I hit puberty! I'm 30 now, and I wish I had used something like this early on because my pores are severely damaged now. DO apply it every other night, or even every 2 nights at first. If your skin is irritated, wait until the irritation goes away before reapplying. Your skin will get used to it eventually. For me, it has only taken 2 weeks. F 30 30 days
1X day
9/27/2011
 1  Acne Dryness, peeling skin, redness, itchiness, soreness and slightly swollen skin. Used this product 3 times, a thin layer just before going to bed each time. The third morning when I woke up, my skin was extremely sore, peeling, and irritated. When I washed my face, it felt like extreme burning for most of the day. Applying makeup wasn't a good idea as it irritated my skin even more and removing the makeup caused for pain. I won't be trying this cream again. F 16 3 days
30mg 1X day
9/25/2011
 2  Acne Extreme burning sensation, dryness of the skin. Although Differin did aid my fight against acne, it didn't go without consequences. My face is so sore, I can't apply makeup or aloe or even touch my face without it burning. When I sleep, I have half my face against my pillow, but it even hurts to do that. F 16 2 months
1X day
8/3/2011
 2  cystic acne After the first week my spots seemed smaller, but now they seem to have evolved a little bigger in diameter, but not as puffy, however redder. I have been applying Differin Creme (must act differently from Differin Gel, donīt know) but apply aloe vera gel over it once it has dried. My skin isnīt too oily, so after having read the reviews am worried about the extra dryness. I canīt say Iīm satisfied with the results just yet, however will try to see if it works. Differin is said to promote the formation of collagen which helps not to scar. Thatīs why I have read itīs good for wrinkles in some cases. Then I guess itīs worth the long process, just hope it works for me. Good luck to all! F 38 2 weeks
0.1% 1X day
7/14/2011
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 5  Mild, Moderate, and Hormonal Acne Burning and dry skin PLEASE PLEASE READ! When I first started using Differin, I was using it incorrectly. This may be the issue with some of the dissatisfied reviews. Yes, this is an annoyingly lengthy routine, but it works. In most cases your acne will get worse before it gets better. This wasn't a selling point to me, as I'm *very* self conscious about my acne, but I tried it. I have sensitive skin, so I know how the burning side effect can be an annoyance, but please read. AT NIGHT, THIS IS MY ROUTINE 1. I wash my face with Fragrance-Free Neutrogena Original Formula. This is the bar soap for sensitive skin. 2. I PAT my face dry, wait a few minutes (I usually brush my teeth during this time). 3. I apply Tea Tree Skin Clearing Toner (from the Body Shop). Here, you'll notice all of the excess dirt/oil that is hindering Differin's effectiveness. 4. I wait 20 minutes and apply a pea sized amount of Differin all over my face. 5. I wait another 20 minutes and apply Neutrogena's Oil-Free Moisturizer for Combination Skin. It is absolutely imperative that you use a moisturizer. Small whiteheads will start to appear after using this product for a short time. This is the medicine working. Your pores are finally expelling all of that embedded oil. If you have moderate acne, I strongly recommend this product. It is worth it. F 25 2 months
.3% 1X day
7/11/2011
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 3  mild acne i have some white heads here and there and redness. My skin also got very sensitive. I barely started. but so far so good. I was worse before i started and thats because i don't even have a week using Differin. :) F 17 6 days
pea sized 1X day
7/6/2011
 5  mild acne redness, burning, really dry skin i love this product. i've used this product for over 4 years and i dont know what i would do with out it. Yes the side effects are horrible BUT they only last a few weeks. remember it has to get worse before it gets better. its all worth it in the end!!! F 19 4 years
1X day
6/8/2011
 4  moderate acne, mild wrinkles Itching, burning, red and swollen eyes with increased sensitivity to any other products. Miserable. Have experienced these awful side effects off and on during my usage; could not understand why as I never apply the differin to the eye area. Still, excellent results-acne is gone, so was hesitant to give it up completely...have pinpointed the problem. NEVER apply differin to any area of the face before engaging in any activity that induces sweating. It will run into and around the eyes causing these horrible side effects. Apply only at night and wash off before engaging in strenuous activity. No more burning!!!!:) F 23 4 months
1X day
6/1/2011
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 3  Acne Itchy and red, puffy eyelids. Itchy, bumpy, rash on neck. Face seemed a bit puffy as well. Differin did appear to help with my acne. However, due to the side effects described, I decided to discontinue use of it. I tried stopping it for several days and restarted it using it less frequently several times. Each time I tried this, my rashes would clear up and then got even worse each time I restarted it. F 56 21 days
.3% 1X day
5/15/2011
 1  Daughters teen acne Redness all over face. Severe burning feeling. Extremely dry skin. All this after only 3 days of use. I felt so bad for my 13 yr old daughter. She was crying because her face was burning so bad. We stopped using Differin 2 days ago, and her face is still red and sore. NEVER AGAIN! F 13 3 days
1X day
5/10/2011
 5  Moderate Acne some dryness I LOVE this product!!!!! It's is the only one that's ever worked for me.. I've had acne for years now and unfortunately I also have eczema which gave me a lot of trouble as a teen. Fortunately, I was able to find a balance... I use Differin every night and use a Gold Bond skin therapy cream during the day to help with the dryness. I would recommend this product to anyone! I haven't gone a day without it since i started using it back in 2008 F 20 3 years
45 MG 1X day
4/6/2011
 1  Mild acne and fine wrinkles BURNING....REDNESS AND MORE BURNING!!! My skin peeled a little where it's bright RED and too sore to even touch!! I wish I knew what I could use to sooth this burning...nothing has worked- NOT EVEN ALOE SOOTHES THE BURNING. I will never use this product again! OMG my skin in so RED and so SORE I can't even touch it without wanting to cry it BURNS so badly!! F 35 9 days
.003% 3X W
4/5/2011
Email
 4  Hormonal Acne redness, drying, flaking I've only been using Differin for two weeks. So far the only difference I see is in the texture of my skin. I had to add my comment to stress how important it is to keep the ointment AWAY from your eyes, corner of mouth, and nose. I look like I have the strangest sunburn and the peeling is a bit embarrasing. Make sure to pick up a moisturizer to stick in your purse while you're out. Neutrogena sells a travel size oil-free mousturizer with SPF that work great for my dry skin. F 23 2 weeks
1X day
4/4/2011
 5  severe acne little Only prodruct that helped my 14 year old son. For the first time in a year he has clear skin! Be pacient, it really works after 6 to 8 weeks. M 14 3 months
pea size 1X day
1/27/2011
 5  severe acne My acne worsened during the first three months, but it was already so horrible before I started, that I decided to stick with it, and I am SO glad! During the fourth month my acne started improving. The biggest change occurred around month six. My cheeks, chin, and forehead used to be completely covered in small white bumps, and I also had large painful pimples on my face and back. Now my skin is completely smooth and the scars have mostly faded. I feel grateful every single day that I found Differin and that I didn't give up on it during those first 3 months. Make sure to follow the instructions and keep using the product for at least 6 months before giving up. Differin saved my skin and my life! F 23 9 months
pea sized 1X day
1/9/2011
 2  acne everyone here is being effected by dryness of the skin but to me I am only getting oily skin a couple minutes after I put it on in the late evening and all night long so of course I am waking up again with more pimples. Is this just my pores being flushed out by the product? I know four days is not a lot of time for the product to take full effect but I am wondering why I am getting oily skin from it. I am also using Benzoyl Peroxide creamy face wash 4% and doxycycline hyclate pills for acne. M 20 4 days
45g tube 1X day
12/29/2010

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