DIFFERIN Reviews (ADAPALENE)

Average Rating: 3.0 (197 Ratings)

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 DERMATOLOGICS

 Type: Rx Drug

  

DIFFERIN  (ADAPALENE):  This medication is used to treat acne. It may decrease the number and severity of acne pimples and promote quick healing of pimples that do develop. Adapalene belongs to a class of medications called retinoids. It works by affecting the growth of cells and decreasing swelling and inflammation.   FDA Approval Date: 1996-05-31 (Sources: U.S. Centers for Medicare Services, FDA)

  

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Key to Ratings: 1=LOW (I would not recommend taking this medicine.)
5=HIGH (this medicine cured me or helped me a great deal.)

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More on DIFFERIN: Reviews Summary  |  Drug Safety Information

RATING  REASONSIDE EFFECTS FOR DIFFERINCOMMENTSSEXAGEDURATION/
DOSAGE
DATE ADDED
 
 2  moderate acne dry skin, eyes swollen shut, inflamed stinging skin, redness, acne don't do it F 18 50 days
4/23/2019
 1  Doctor prescribed it for me It does work at first, however over time your skin goes terrible! It goes all flaky and it makes my whole face after I wash it with a flanal really tight like I can't feel it! I would not recommend this gel, I hope my skin isn't always like this! I put it on my forehead first but then my inner cheek by my nose and my chin, and now my whole face feels dry! Don't use this I've been putting Aveeno cream on for months now and still no result! My skin is still dry and always peels! Also do not get your eyebrows waxed after using differin, you will have raw flesh showing around your eyebrows, your skin will get greasy and it gets really tight and it peels, I had this for 2 weeks so avoid having brows done if you do use differin but I recommend you don't! F 15 4 months
8/26/2017
 5  Acne (post Accutane upkeep Sensitivity to sun and wind. Dryness that fades with regular use. This medication, when used religiously, has done a pretty good job of keeping my post-accutane skin clear. I certainly have more acne than during my Accutane treatment, but i can tell Differin is working wonders! Because when I start getting cocky about my clear skin (Accutane worked wonders for cystic and nodular acne) and skip applications, I tend to get breakouts of more "simple acne" again. When I use differin regularly, evenings and every other morning, i am very happy with my skin. To be fair, Differin can only do so much. It cannot completely stop the hormonal acne I get each month, but my skin does recover quicker from those breakouts than if I didn't use differin. Overall I am super satisfied because it keeps my pores tight, skin clear, and surface of my skin quite beautiful, on average. F 29 12 months
0.01%
8/11/2017
 1  My 12 year old daughter My daughter's skin is SIGNIFICANTLYING worse now than before differen gel. Inflamed burning severely chapped skin painful. My poor girl. Horrible stuff never again! F 12 3 days
.1%
6/13/2017
 5  Mild adult acne, anti-ageing First 2-3 weeks: Increased dryness and sensitivity Weeks 3-5: Purging breakouts including whiteheads on chin and deeper acne on jaw (my problem area). An overwhelming majority of negative reviews for this treatment come from incorrect use and insufficient treatment time. A tiny amount is required per treatment. When dermatologists say pea sized amount they are in fact often referring to a dosage no bigger than two grains of rice. Differin is to be applied to gently cleansed skin (no beada or grains or exfoliants, no foamimg as this will further strip the skin - gel, lotion or cream textured gentle/sensitive skin cleansers are very important) after the skin has completely dried (5-20mins). This is not a spot treatment and should be used all over the face. Moisturising sufficiently after use is absolutely imperative. Layering serum and moisturiser and topping off with a min spf 30+ works well. Again, only moisturise after treatment has completely absorbed (5-20mins). Finally,be patient. I repeat, be patient. This product works at a minimum in 3 months, however, best results are seen from months 6-8 in some cases. Acne is no joke and requires serious,committed treatment to successfully treat. You'll be pleased to know that patients have also reported antiageing benefits and an improvement in overall skin texture. F 30 9 months
4/26/2017
 4  acne When I first used the product I noticed a little redness for a short time, other than that none. I have hormonal acne mostly on the jawline and sometimes around my nose. I also have some closed pores on my forehead. I have been using generic differin for a few years now, but I really didn't notice any significant improvement until after a few months of use. I also use another topical called clindamycin gel on occasion. Overall I think this is a good product that has helped me. The over the counter junk does not help my acne at all. Differin is a pretty good overall maintenance product. F 51 2 years
1X day
12/19/2016
 2  Breakouts Dry skin, itchiness, lots of peeling and redness around corners of mouth and eyes, burning face I loved this so much the first week. My face didn't look different with or without foundation and I have no pimples. However after the first week my face become incredibly dry and my skin had started peeling around my mouth. Just before this I had to stop using any makeup at all due to the fact it burned to put on and take off, so unfortunately I couldn't even try to hide it. I assumed it was my dose so I used it every other night and my condition still worsened to the point it was peeling all over my face and it would burn to even put my face on my pillow at night. No acne but not worth the burning and peeling I have everyday. F 17 1 weeks
3/9/2016
 4  acne vulgaris concerned because i plan to get pregnant soon and afraid my acne will return once i come off. any suggestions of safe weaning off this medication without breakouts? F 39 3 years
1X day
1/2/2016
Email
 1  Under the skin acne Burning sensation on face and very red and sore. If your skin is in any way sensitive do not use this product. I was on roacutane for a year and did not experience side effects as awful as this. After using a thin layer over my spots on one night less than 24 hours later my face started to develop red blotches which soon turned to burning red areas encompassing my forehead and right cheek. I was so worried I even called the NHS helpline number and went to my GP. I repeat do not use if you have in any way sensitive skin. The cons far outweigh the pros. F 19 1 days
1 / night
11/27/2015
 3  Acne Burning skin - peeling skin around eyes and mouth. Red and itchy blotchy skin Worked and treated spots at first and was really pleased. About a week after using the product my skin was sore and really dry - got to the point where the pain wasn't worth putting up with. Had to stop using it as the pain got too much F 20 10 days
11/7/2015
 1  Acne Dryness of the skin, I had a few minor spots and after applying once it has made my acne a lot worse Made my acne a lot worse F 21 1 days
Once
3/29/2015
 5  Face Acne/ Hidradenitis Suppurativa If I used the cream for more than 7 days continuously my face would get VERY sensitive and even water would cause it to burn. Not good when at the gym eather as the sweat would also cause my face to burn. Even rubbing with a towel hurt. It basically felt like SUNBURN. But this was using it constantly. I'm now taking breaks. Also it does ger worse before it gets better but after the 'worst' part you'll never have acne again like that after using it. Take breaks between using it. Cover your face with a towel if you want to use sun beds. Apply moisturiser in the morning after using it during the night. F 21 3 months
2/26/2015
 3  for acne and spots Burning redness wonderful cream really works F 33 10 days
2/24/2015
Email
 4  breakout micro peeling, gets worse before gets better I used to have clear skin until November last year. I tried using apple cider vinegar diluted with water but it was to drying for my skin and caused morw breakout. I went to the dermatologist and she prescribed me with adapalene, though it can be bought otc here in the Philippines. On my first week it really gotten worse I got pimples even on areas I didnt have before but it seems to dry easily. Tomorrow it is already my 3rd week of using it I am really satisfied with it since my derma said that normally it would take 3 months before one can see a result. F 27 3 weeks
2/10/2015
Email
 5  Acne Burning sensation the first week or so This really worked for me when nothing else did. It gets worse before it gets better but my skin never looked better once it started working and eventually after about a year or so I didn't even need to use it. My breakouts stopped until I got pregnant. It was a miracle drug for me and the burning will stop once you use it for awhile you have to use it every day though and just try to deal with the burning while it last it's worth it in the end or at least it was for me. F 20 3 years
thin film 1X day
1/2/2015
 1  Mild spots under surface of skin So dissapointed with this, I had mild spots and it peeled away my skin leaving scars and indents. I did not have any scars at all befor using this. F 21 1 months
10/11/2014
 2  to fade acne scars burning skin near eyes. dryness around sides of mouth more acne where there was none before didnt fade acne scars F 28 3 months
pea size
9/18/2014
 5  Acne None really Been applying a thin layer every night and waking up with less and less spots. Been using it alongside Yasmin contraceptive, not sure which one is doing the clearing up but together they are clearing my face up good! No dryness from Differin really. F 24 2 months
1X day
9/17/2014
Email
 2  Dermatologist recommended If you use too much, like me you will have a reaction with red splotches on your skin that kinda feel like burns. If you are using differin I would suggest the .01% and deluding that with lotion. I made a pea size and I had this bad reaction and I know I'm about to have it again. F 14 4 months
6/17/2014
Email
 1  Acne Dry dry dry dry skin F 14 3 days
5/20/2014

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