Average Rating: 3.4 (1891 Ratings)

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 Type: Rx Drug

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Key to Ratings: 1=LOW (I would not recommend taking this medicine.)
5=HIGH (this medicine cured me or helped me a great deal.)

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More on LAMICTAL: Reviews Summary  |  Drug Safety Information

 1  Seizure disorder Difficulty walking properly, feeling foggy and like I might fall, dizziness ( vertigo) memory issues. Physician pressures me to take thinks I may have seizure M 80 1 years
175 mg day 2X D
 1   I have been feeling so terrible these last few months, initially I had indicated to the prescriber that I was feeling terrible and she disregarded my opinion. These last two months I've been drained of energy, especially in the morning. I wake up at random times during the night (even with a sleeping medication of 150mg), nonetheless, the red color on my knees comes and goes, followed by joint pain. My arms, knees, hips, ankles are always in pain, and cracking. I have limited cognitive functionality. I do not retain as much information as I used to, my head always feels like its on fire. I get rashes from time to time on my legs, and arms, my neck is stiff. I dislike this medication. It's been ruining my life, I do not recommend. F 22 4 months
100 1X D
 5  Bipolar 2, irritability, anxiety None. Eliminated my extreme irritability almost completely. It has brought me such relief. Life altering. F 51 2 years
200 1X D
 2  anxiety/ mood disorder NOS Extreme brain fog, fatigue, depersonalization/derealization. Irritability, worsened anxiety, intrusive obsessive thoughts, behavioral concerns, low mood. Cognitive impairment, including problems with attention, memory, processing speed, etc that significantly affect ability to function and carry out ordinary life tasks. I feel after coming off the cognitive impairment may be longterm. Seemed the main effect was to feel separated from one's emotions while still simultaneously experiencing them. Note: In comparison to other anticonvulsant and "mood stabilizer" options, lamictal is usually tolerated better and viewed as less extreme. For example, fatigue from lamictal was less extreme that fatigue from gabapentin. F 20 6 years
150 mg 1X D
 1  depression The pills were so tiny that I wondered if they would do anything at all. But after taking 1 pill, then another the next day ( in the morning ), I experienced horrible restless insomnia when I tried to sleep that night. I didn't take any more, but I could hardly get through the next day because I felt so bad. I think that there are too many drugs on the market that have an insomnia side effect. How can a prescription drug help depression if it causes insomnia ?? I can't think of too many more counter-productive side effects than insomnia, especially for depression. F 74 2 days
50 mg. 1X D
 5  Bipolar None Lamictal eradicated my bipolar depression. Changed my life. M 53 11 years
100 MG 3X D
 5  Bipolar 2, anxiety, panic attacks A little dizzy at times I just started taking lamictal along with my prozac 20mg. I have been on and off SSRI's for years for depression and anxiety and recently Dx bipolar 2. I am already feeling my depression lifting and my old self returning. I am hopeful that I continue to feel good on lamictal. So far I am extremely satisfied! I am very fearful of trying new medication but I am so glad I did!!! F 54 0 days
25 mg 1X D
 1  Depression, Bipolar It was ok at beginning low dosage then everything was increasing then it just kept getting worse, severe hot flashes, night sweats, dry mouth, insomnia I could take it, know I'm SLOWLY going odd it and realizing what this did to me and my body, very hard getting off with withdrawals but DEFINITELY doing it!!!! F 56 3 years
250 mg 1X D
 3  Seizures, depression, PTSD, anxiety I have been experiencing a considerable amount of loss in coordination, I cant even walk in a straight line without teetering to one side and almost falling. My brain feels tingly and I get severely light headed when I move it up and down (and sometimes side to side).I have had terrible insomnia to the point of staying up for three days in a row. I sometimes get these moments of intense nausea where I feel like I'm going to throw up. I find myself increasingly zoning out of conversations and have a hard time retaining memories. I have noticed that my speech and conversational skills are lacking and I have begun to competely forget about how to pronounce certain words as well as remembering them. I have been having severe muscles pain in my shoulders and neck to the of point no being able to move them past a certain point. I have had minor weightloss and little to no appetite, sometimes I only eat one or no meals in a day. Currently I am at 250mg per day, but in two days I will increase to 300mg(150 in themorning and night). This making me worried because I fear my side effects will worsen to the point of injuring myself by simply walking/knocking into things and gaining an alarming severe vertigo when I move my head. Also I have developed a small bug bite like mark on my stomach and it kinda freaks me out because it might turn into a rash. I have not had seizures, depressive episodes, or forceful intruding thoughts; but this might be short lived since I am only at 13 weeks. F 20 3 months
I50mg 2X D
 4  Seizure I had my first and only seizure a few months after brain surgery. I was put on Keppra and felt irritable and easily agitated. They switched me to Lamotrigine 200mg twice a day. It's worked in preventing any more seizures but I also feel it's dulled my emotions- but more my happiness. I still cry and feel sad emotions but when I get happy, it's like there is this ceiling to my feelings that suppresses how excited I feel. I don't know if it's timing- 9 months after surgery, Covid became a thing, so I wonder if it's a mix of post-surgery emotional recovery, pandemic life, or medication. F 32 1 years
200 2X D
 3  Epilepsy Very restless sleep, struggle getting to sleep, lack of motivation, depression, anxiety. Dosage has just been increased so all of the above has just gotten worse!! Particularly my dreams. Wake up feeling like I have studied all night. Like others- after waking at times not sure if it was just a dream or it actually happened F 45 5 years
40mg 2X D
 5  Depression, anxiety, rapid cycling This drug has been life changing for me. You need to sloooowly titrate up. I've gone from 25mg to my now ideal dosage of 200mg split 100/AM and 100PM. I am not so super sensitive and can now step back and see the whole picture and stop feeling like the world is going to fall out from under me. After 15 years of medication, I've found the one. No weight gain, or side effects at all besides oilier skin and a little more sweating than normal. Also increased my sex drive and actually helped my focus at work. F 38 3 months
100mg 2X D
 4  Unipolar depression A bit of insomnia. A bit of fatigue at the beginning of my treatment. It worked better than any SSRIs for me. I felt the effect right in the moment of my first dose. M 54 1.5 years
50 mg 1X D
 5  Depression/Anxiety Helped reduce mood swings, helps with anxiety. Iím very pleased with how Lamictal works for me. No negative side effects. F 58 2 years
125 MG 1X D
 5  bipolar diarrhea this med has been great for curbing my highs and keeping me out of my lows M 26 2 months
200 mg 1X D
 1  Bipolar II I took this drug about 7 years ago and now I have random muscle spasms all over my body throughout the day. Consumer Beware! M 3 months
1X D
 5  Unipolar depression Mild somnolence and insomnia. Anxiety at the beginning of the treatment The only med that helped with depression for me, after taking several antidepressants. Side effects are very tolerable and transient. M 54 2 years
50 mg 1X D
 3  panic attacks really no side effects in the 1 st week, im un the middle of my 2nd week, some itching although its winter and i get dry anyway. A little gassy, and bloated to the point i feel like i gained 10 pounds Buspar for me was the best without any side affects, but Lamictal is better than Prozac, but i am loosing my hope with anxiety medications. I am still nervous, very nervous, and hope i get better soon. F 43 12 days
2X D
 5  Anxiety Works great with no side effects which I canít say about any SSRI Iíve tried. For me much better then several SSRIs, Buspar, aglomelstine, and gabapentin. M 66 1 months
 4  bipolar bloating/stomach cramps, intense pins-and-needles sensation all over body at random intervals, sleep disturbances I've taken this drug on and off for a few years now. Just started increasing my dose and finally made the connection between my at times debilitating pins-and-needles, with this drug. It's tricky to do simple things like unbutton my pants or make the bed, let alone drive or perform work. It never goes away for more than 24 hours unless I am totally off the med for a few weeks. It seems to happen most often at night, which is around the time I take the medicine- maybe I should ask my doctor about going to two smaller doses twice a day? Could this be a withdrawal symptom as it happens near the time i should be taking my next dose, or is it from the med? F 24 3 years
100 1X D

LAMICTAL  (LAMOTRIGINE):  Lamotrigine is used alone or with other medications to prevent and control seizures. It may also be used to help prevent the extreme mood swings of bipolar disorder in adults. Lamotrigine is known as an anticonvulsant or antiepileptic drug. It is thought to work by restoring the balance of certain natural substances in the brain. This drug is not approved for use in children younger than 2 years due to an increased risk of side effects (such as infections).   (Sources: U.S. Centers for Medicare Services, FDA)