Average Rating: 3.5 (21 Ratings)

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 Type: Rx Drug

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Key to Ratings: 1=LOW (I would not recommend taking this medicine.)
5=HIGH (this medicine cured me or helped me a great deal.)

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More on CONTRAVE: Reviews Summary  |  Drug Safety Information

 1  Weight loss Horrible vomiting, nausea and weird thoughts about 3 hours after my very first dose. Had to go to ER to get fluids and phenergan administered intravenously. I will not continue this medication. F 47 1 days
150 1X D
 5  Weight Loss I have not experienced any side effects, it has helped my moods a great deal. I have been taking Contrave for 2.5 weeks and I have lost 7lbs! It has increased my energy levels and I feel better emotionally. I noticed a slight headache when I didn't drink enough water one day. I recommend drinking 1/2 of your body weight in water. I also noticed that there were times when I felt hunger, but I was just thirsty, so when I feel that way now, I just grab a sugar-free popsicle. I don't do a lot of exercise because I am walking all day at work in the hospital. I have occasionally walked/jog 1.5 miles on my running pad. Overall I am extremely happy with Contrave and I am excited about the weeks to come. M 48 2 weeks
8/90 2X D
 1  Wanted to loose 30 lbs All I wanted to do was sleep and eat. I get up at 7 am each morning. By 830 am I am falling asleep watching the news. I forced myself to stay awake. I actually lost 3 lbs the first two weeks. Then at a stand still. I tried so hard not to eat but I would give in. I need something to help me not to eat. F 74 30 days
8 mg 4X D
 4  Weight loss. Depression. High chole Slight nausea and headaches for first 2 days. This medication has helped me to change my way of thinking (it's a tool) I now eat to live and enjoy creating/eating healthy foods. 2Kg down in 5 days. F 40 5 days
1 tab 1X D
 5  Weight loss Constipation, nausea, feeling really tired by evening I lost 6 pounds in the first 2 weeks. I haven't been to the dr, so I don't know how much weight I've lost. My clothes are fitting a lot looser. Controls my hunger and cravings. F 43 30 days
2X D
 5  Weight loss Only side effect I had was slight brain fog and trouble breathing when I reached 4 pills a day. When I cut back to 3, both side effects went away. I lost 35 lbs in 6 months. I have since continued to take 1 pill a day for maintenance, and only eat when I'm genuinely hungry. Very few days of cravings. I've occasionally had a glass of wine or a drink. For my body, alcohol negates the effects of contrave, and makes me want to eat. So I stopped the occasional glass of wine. Not worth it. Pill has been a godsend for me. F 42 1 years
1X D
 1  Weight loss Constipation Did not curb my appetite whatsoever. Stopped taking after 3 1/2 weeks. M 70 24 days
8-90MG 4X D
 1  Weightloss 90 Super nauseous with headache similar to car sickness or morning sickness that lasted alll long. Extreme tiredness and grogginess to the point of not being able to function and had to try and sleep it off. No matter how much I slept it was never enough and the sick feeling only got worse after increasing the dosage. This drug absolutely got rid of my appetite, but the side effects were not worth it. F 36 14 days
2X D
 5  Weight loss Low level nausea for first two weeks. I was still able to function with day to day activities. I was prescribed this medicine for weight loss, as I have a binge eating disorder. Started 12 weeks ago, and have lost 28 lb. Contrave curbed my appetite from the first time I took it. I did have low level nausea for two weeks, but I stuck with it, and it resolved. No other side effects. Oh, except one. Iíve drank coffee for 25+ years, and a month into this regimen, I noticed all the sudden I didnít want coffee (or caffeine in any form). So while this pill treats me for my addiction to food, it also helped me to get off of caffeine. Very happy with the results. F 43 12 weeks
2X D
 4  To lose weight and stop cravings Having severe constipation. I have a gastric Bypass, it is helping with my appetite and cravings though and this is why I take it! I have lost 8 lbs. in 1 1/2 months. F 64 2 months
2/AM-2/PM 2X D
 2  Weight loss I am taking 2 tabs in AM and 2 tabs in PM. I am eating MUCH less but I do NOT seem to be losing ANY weight. I do not weigh myself, but judge my weight loss on how my clothes fit. My appetite is substantially reduced. I do drink a couple of glasses of wine in the evening but how in the world can I NOT be losing any weight? I exercise everyday. I have noticed more fatigue than usual. EEEK! Somebody please give me some guidance or feedback. Thank you. Very expensive even with discounts. I have yet to experience desired results. Very frustrating. F 64 30 days
8-90 mgx2 2X D
 5  Weight loss Dizziness, extreme tiredness, slight GI upset. Only slight dizziness by 3rd day. Im feeling good. Little side effects and planning to start 3 pills a day tomorrow. I havent thought about food and have hardly ate the last 3 days. Ive lost 6 pounds already! F 44 3 days
1 pill 2X D
 3  Lose weight Dizziness, nausea, constipation, and neck pain. Serious neck pain Will likely discontinue due to neck pain. Lost 14 lbs so far. F 39 4 weeks
Full dose 2X D
 3  lose weight nausea, constipation, neck pain, back pain and stomach issues I quit taking it - the side effects outweigh the benefits. i have been off of it a week and still feel crappy from it. Would not recommend F 68 30 days
as directe 2X D
 5  Weight loss I tried Contrave 18 months ago and continued to drink alcohol. I suffered a very depressive effect and quit after 30 days. After reading on here about other's success, I tried again, significantly reducing my wine consumption to 2 glasses per day only about 3 days a week, I've had no ill side effects. It really works! This time I've lost 30 pounds! I'm 6 foot and was 216, so not morbidly obese. I've coupled it with intermittent fasting and that has changed my life. I give Contrave lots of the credit but what it really takes is will power to Stop Eating. M 66 75 days
8mg/90mg 4X D
 5  Weight loss The only side effects I have noticed is I shake and am tired in the afternoon. I was considered obese before starting this, but since taking it my depression has lessened to the point I'm not considered a "Debbie Downer" anymore and I have lost 32 pounds so far. I work out regularly and get full much faster, so I'm not eating until I am sick anymore. I still crave sweets, but don't eat near as much and I drink a lot more water. F 38 22 months
 5  Over weight Love contrave because I don't want to graze all day or Bing eat. The side effects are anxiety. Clenching my jaw. And chest pains after a work out. Won't stay on it because of chest pains. Stops your food addiction. F 54 15 days
 5  Weight loss and anxiety This is my first week of taking Contrave but I could tell a huge difference the first day without any side effects. After doing very well on WW and losing a considerable amount of weight, all of a sudden I started gaining and gaining fast. My doctor adjusted my Synthroid and that seemed to make it worse. I gained almost 30 lbs in five months which is why I believe I was having the anxiety. Right now I really don't have any appetite at all so it is easy to control what I eat. Interested in knowing how I will be doing in four weeks once I am up to the full dosage. I'll report back with my status. F 62 5 days
8 mg/90 mg 1X D
 5  weight loss Prior to Contrave I was a sugar-a-holic. I woke up wanting ice cream, spent the day wanting ice cream or other high sugar content foods, and I went to bed wanting more of the same. About a week after starting Contrave I noticed I was not thinking about sugar foods anymore. Instead I would wonder why I was not thinking about ice cream any longer. That lasted for a few days,since then no sugar adiction. I dont think about food until I get hungry and have the ability to choose healthier foods. I am down a bit over 20 pounds without actually trying. I worry a bit about what will happen when I go off Contrave but I guess I will cross that bridge when I come to it. F 52 10 weeks
2X D
 3  weightloss Brainfog from RA subsided. Chronic fatigue from RA subsided. Allowed me to stop using steroid treatment first time in three years (since onset of disease). I feel as though I have awoken from a comatose state. Amazing drug in that regard. As far as weightloss goes, this drug does not work by itself, one must be fully committed. In that regard I have managed to lose 8 pounds in less than two months. Losing this weight has required me to stay focused on other things rather than what to eat next. I think Contrave has helped. Whenever I feel hungry, I prepare hot green tea or water with lemon instead of getting a snack. This medicine allows my mind to accept these refreshing drinks as a replacement for food whereas before I could not stop fixating on eating. F 51 57 days
8/80 4X D

CONTRAVE  (BUPROPION HYDROCHLORIDE; NALTREXONE HYDROCHLORIDE):  This medication is used with a doctor-approved exercise, behavior change, and reduced-calorie diet program to help you lose weight. It is used by certain overweight people, such as those who are obese or have weight-related medical problems. Losing weight and keeping it off can lessen the many health risks that come with obesity, including heart disease, diabetes, high blood pressure, and a shorter life. Naltrexone belongs to a class of drugs known as opiate antagonists, and bupropion is an antidepressant that may help restore the balance of certain natural chemicals (neurotransmitters) in your brain. These two medications work together on separate parts of the brain to reduce appetite and how much you eat. Most opiates should not be used for 7 to 10 days before starting naltrexone, but some opiate drugs (such as methadone) should not be used for 10 to 14 days before starting naltrexone. Ask your doctor or pharmacist for more details. Other forms of naltrexone or bupropion are used to treat a variety of conditions including depression, other mental/mood disorders, smoking cessation, addiction to narcotic medication, and alcohol abuse. This combination product is not approved for these other uses. Discuss the risks and benefits of this medication, as well as other ways to lose weight, with your doctor.   (Sources: U.S. Centers for Medicare Services, FDA)