ANAFRANIL Reviews (CLOMIPRAMINE HYDROCHLORIDE)

Average Rating: 3.7 (133 Ratings)

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 ANTIDEPRESSANTS CNS, MISCELLANEOUS

 Type: Rx Drug

  

ANAFRANIL  (CLOMIPRAMINE HYDROCHLORIDE):  Clomipramine is used to treat obsessive compulsive disorder (OCD). It helps decrease persistent/unwanted thoughts (obsessions), and it helps reduce the urge to perform repeated tasks (compulsions such as hand-washing, counting, checking) that interfere with daily living. This medication belongs to a class of medications called tricyclic antidepressants. It works by restoring the balance of certain natural substances (serotonin, among others) in the brain.   FDA Approval Date: 1989-12-29 (Sources: U.S. Centers for Medicare Services, FDA)

  

Results are sorted by Age from youngest to oldest (reviews with no age reported listed first).

Key to Ratings: 1=LOW (I would not recommend taking this medicine.)
5=HIGH (this medicine cured me or helped me a great deal.)

Page: 1 2 3 4 5 6 7


More on ANAFRANIL: Reviews Summary  |  Drug Safety Information

RATING  REASONSIDE EFFECTS FOR ANAFRANILCOMMENTSSEXAGEDURATION/
DOSAGE
DATE ADDED
 
 5  Panic disorder (Severe) Dry mouth, blurred vision, constipation and of course very reduced sex drive This stuff works so much better than anything I have ever been on and I have tried most. Removes completely panic symptoms and greatly reduces anticipatory anxiety - fantastic med if only it didn't kill your libido. I am currently trying different meds, SSRI's - no good for me now on Moclobemide and sex drive back but so is panic! Will be going back on Anafranil ASAP. M 4 years
7/30/2006
 5  OCD Difficulty getting to an orgasm. It has helped the OCD to a great deal. I've tried replacing it with Prozac, it didn't work at all. I switched back to Chlomipramine (Anafranil) again. 12 years
6/26/2007
 5  depression, anxiety, obsessions Dry mouth, slight fatigue, some sexual problems I have only been on this medicine for a week and it has been a GODSEND!! After only four days I started feeling better and each day is an improvement on the last. I recomend taking this with huperzine A to counter the anticholinergic effects. This medicine puts zoloft/Prozac/lexapro to shame. The SSRIs have more side effects (don't believe the anti tricyclic marketing) and can barely come close to the fast depression relief anafranil has offered-much less the anxiety and obsession relief. This drug has cured my mind of all doubts, worries, obsessions and paranoia and has left me with clarity to concentrate and happiness to show compassion once again! If your afraid of the side effects, done be, just give it a try and your life as well as those of your loved ones will benefit ! M 7 days
1/28/2008
Email
 5  Depression/Anxiety/Depersonalizatio None as yet I have tried Aropax/Zoloft/Luvox/Clonoazepam/Xanax and more recently Cymbalta - most of these with valium, as needed to varying degrees. The side effects of these drugs as well as there inefficacy has led me to try Anafranil - Having only been on this drug for about a week i have felt much better! Less distracted and able to concentrate on uni, and the people i care about. M 6 days
5/13/2009
 5  ocd, anxiety, depression I first took this medicine in 1992 when I was diagnosed with ocd, anxiety and depression. I felt well and lived a wonderful and productive life but when I became pregnant my psychiatrist told me I had to stop taking it as it was not a "safe enough" drug during pregnancy. After, I tried other anti-depressants but they always stopped working after a number of years. Finally, after having reached rock bottom a month ago, I asked my doctor about anafranil and believe it or not, from the first day I took the small dose of 25 mg, I felt a change in my head. I now am happy, healthy and the intrusive thoughts are almost gone and when they do appear, they disappear so fast and the anxiety associated with them is not there. Yes, there are some side-effects but there are with every medication. I would highly recommend this medication to anyone suffering from these illnesses. M 5 weeks
100 mg
3/27/2014
Email
 3  
12/26/2001
 3  
1/21/2005
 3  
3/1/2006
 1  
12/4/2008
 4  OCD and anxiety and social phobia dry mouth and a bit dizzy when i get up to quick anafranil has helped me a great deal F 13 6 months
10/5/2005
 4  OCD Lethargic, Nauseous I'm already feeling a great effect, even though it hasn't even reached full strength in my body yet. The only bad thing is that I'm very drowsy, and I can't aim a ball as well as I could before. M 14 17 days
25mg 1X day
7/5/2011
 2  Trichotillomania/OCD dry mouth, spasmodic motions of neck head and hands, orgasmic yawning, extreme weight loss (16 pounds) Anafranil has not worked for me at all. I still pull everyday. As far as side effects, I'm also taking several other medications for ADD/ADHD, so they might not all be valid. However, the spasmodic movements were definitely a result of anafranil; and the movements are SO annoying. I highly recommend not taking it, however everybodys body chemistry is different F 15 6 weeks
50 mg 1X day
5/16/2012
 5  OCD anxiety My 16 year old son uses this and he has shown literally no side affects at a 50-75Mg. dose. At first his heart raced some but that quickly disappeared. My son has used it now for 1 year. This medicine is an older tricyclic that has a good track record for OCD. We are satisfied but if you use a little anxiety med with it like Ativan it seems to make it really work well.Helps greatly ,his obsessive thoughts M 16 1 years
11/25/2004
 5  Obsessive-Compulsive Disorder Depression, fatigue, tiredness I've tried just about every SSRI available and nothing has ever subsided by OCD the way Anafranil does. I would go as far to call this medication a life-saver. If you're willing to brace some bad depression for the first two months or so of taking it, the effects are very much worth it. F 16 1.5 years
125 MG 1X day
5/26/2020
 3  Anxiety ocd Headache Muscle soreness Stomachache Bitter taste in mouth Been on 6 antidepressants Non worked Last resort was clomiipramine and it is somewhat better then the others I haven't been on it long enough I guess I start my 10th week today Still getting side effects remaining hopeful I hear it takes time to work for some Best luck to us in need of peace F 16 3 months
50 mg 1X day
5/24/2021
 5  Severe OCD; Depression; Anxiety Side Effects: Fatigue; Constipation; Good sleep; Good sex M 17 10 months
150 mg
11/3/2013
 4  OCD depression/anxiety no effect on current anxiety problems, weakness, decreased sex drive, loss of orgasm, mania like symptoms in high dose Other then the side effects it completely stopped my OCD, if you have OCD and you don't mind the side effects then this med is great. But the sexual problems completely sucked, so I wont be taking this anymore. M 17 4 weeks
1/3/2008
 5  OCD. mood disorder. depression. M 18 1 days
6/22/2014
 5  Depression, Anxiety, OCD, Paranoia Dry mouth, Lowered libido, Increased sweating during excersize Before Anafranil, my life seemed so chaotic. I was constantly fighting with my parents, struggling to meet demands at school, having friendship troubles due to reluctance to participate in large social groups and crowded events. Also, I would constantly obsess over the way I looked and had an overly cynical outlook/sense of humor, all while feeling guilty for no good reason, and believing that strangers were either critisizing my appearance or annoyed by my prescence. My old life seemed meaningless and it got to the point where all I cared about were a couple friends, any kind of illegal 'upper', and obsessing over my looks and my health. An insane asylum seemed appropriate, as I convinced myself that I was schizophrenic. I would skip class if I was late due to my phobia of being stared at when entering the classroom. I would tense up and begin a negatibe loop of thoughts concerning and obsess for days over what other students were saying about me behind my back (how arrogant of me); M 19 8 days
1/29/2008
Email
 5  panic disorder, anxiety, dread Dizziness, lower sex drive, inability to orgasm, dullness. M 19 6 weeks
100mg
1/19/2013
  

ANAFRANIL  (CLOMIPRAMINE HYDROCHLORIDE):  Clomipramine is used to treat obsessive compulsive disorder (OCD). It helps decrease persistent/unwanted thoughts (obsessions), and it helps reduce the urge to perform repeated tasks (compulsions such as hand-washing, counting, checking) that interfere with daily living. This medication belongs to a class of medications called tricyclic antidepressants. It works by restoring the balance of certain natural substances (serotonin, among others) in the brain.   FDA Approval Date: 1989-12-29 (Sources: U.S. Centers for Medicare Services, FDA)

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