PROMETRIUM Reviews (PROGESTERONE)

Average Rating: 3.1 (568 Ratings)

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 ESTROGENS PROGESTINS

 Type: Rx Drug

  

PROMETRIUM  (PROGESTERONE):  Progesterone is a type of female hormone (progestin). This medication is similar to the progesterone that your body naturally makes and is given to replace the hormone when your body is not making enough of it. In women who are not pregnant and not going through menopause, this medication is used to restore normal menstrual periods that have stopped for several months (amenorrhea). Progesterone is also used as part of combination hormone replacement therapy with estrogens to reduce menopause symptoms (e.g., hot flashes). Progesterone is added to estrogen replacement therapy to reduce the risk of cancer of the uterus. This medication is not for use in children. Progesterone must not be used to test for pregnancy.   FDA Approval Date: 1999-10-15 (Sources: U.S. Centers for Medicare Services, FDA)

  

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Key to Ratings: 1=LOW (I would not recommend taking this medicine.)
5=HIGH (this medicine cured me or helped me a great deal.)

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More on PROMETRIUM: Reviews Summary  |  Drug Safety Information

RATING  REASONSIDE EFFECTS FOR PROMETRIUMCOMMENTSSEXAGEDURATION/
DOSAGE
DATE ADDED
 
 4  Reduce thickness of uterine lining Extremely tired in the afternoons, dizzy when first taking the pill at night. When I first started taking Prometrium I didn't like it, as I experienced extreme fatigue around 2-3pm everyday and I found it very difficult to focus on work. I know everyone is different but I want to reassure other women taking the drug that the side effects should go away after a few weeks. I felt like I was on my threshold for putting up with them around day 10-12 and since I have to take them for 3 months I asked my doctor about the unpleasant side effects. He told me to give it another week. Well I did, and the side effects finally ceased. Now I just pop a pill right before bed, it puts me to sleep and that's it. I go back for a checkup in another month and a half so so far so good. F 30 45 days
11/13/2007
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 1  Start a period I was prescribed 200mg once a day for 12 days. I took it at night for only two nights. It made me feel horrible. Dizzy, tired, anxious, depressed and also I flushed. My skin and the whites of my eyes were visibly red. Weird! I would rather just let nature takes it course, than have to experience this. I am 48 years old....I am asking myself why would my doctor want me to have a period so bad? Maybe I am entering menopause. I will never take this drug or any other hormone again. I might have to find another GYN if she isn't on the same page as me. After all everyone...it is YOUR body. I have found that I listen to doctor's, but then research it myself. Everyone knows their body best. F 48 2 days
11/11/2007
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 4  No period after D&E for missed m/c None! My doctor prescribed me prometrium after I still had not gotten a period 9 weeks after my miscarriage. He prescribed me 200mg, once a day for 10 days but I ended up getting my period on day 5 of the pills. The nurse instructed me to only take two more days after that so I didn't take my last three pills since I already got my period. The only thing different about my period is that it is lighter and lasting about a week (before it only lasted 2-3 days). Now I will be starting Clomid. F 27 7 days
10/15/2007
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 1  hrt nausea, feeling full, pelvic pain, swollen abdomen, crying due to feeling awful, shaking hands, vivid dreams, throbbing in back when lying down, depressed feeling, after 3 weeks and 2 shots of this medication. I tried this because I had pelvic pain. Really created new places of pain and after 3-4 weeks and the shots, nausea, shaking hands, couldn't do anything felt so bad, felt irritable toward people who talked too long. I am disappointed that it didn't help, wonder how long will take to wear off. I also was prescribed Estratest, so could be some of that, too. But when I took hormones at age 50, estrogen didn't bother, only progesterone. This did not give me headaches which I had with the progesterone I took alone when I was 50 and the doses were divided to mimic your period. I don't know why they now combine the two hormones. This med did not work to my satisfaction and I became worse and worse. Thanks for this website and the info, it was very helpful to me. I don't know what will help my pelvic pain and other problems but hysterectomy, which I don't want. F 64 28 days
10/13/2007
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 2  menopausal symptoms Increased anxiety, very dizzy a couple of nights after taking it, weight gain, extreme increase in appetite, migraine headaches, fluid retention, restless sleep, moodiness/depression like symptoms I actually was on this for approximately two months, ...then went off because of a constant headache over and behind right eye. Menopausal symptoms returned...decided to give it another try with the addition of migraine medication to alleviate the head pain. Worse side effects this time round. VERY dizzy after taking it, approximately 1 week into program. Can't seem to fall asleep very easily...cramps in the middle of both calves, wieght gain, which I am definitely not happy about, in that I am very much into fitness, and at barely 5 feet tall, I do not like the extra weight...very uncomfortable as there is also fluid retention in my legs. Would advise not to take this medication..will find another more natural way to alleviate my symptoms with menopause! F 46 1 days
10/9/2007
 1  Low Progestrone Panic attacks, depression, anxiety, very tired all the time. I have been taking this for 12 days and hoping that the side effects I am having would go away, but are not. I have a history of (chemical imbalance) depression, and this is making me feel worse not better. F 49 12 days
10/8/2007
 4  Perimenopausal dysfunctional bleed I take 12 pills per month otherwise I would have erratic bleeding as I'm not ovulationg due to being close to menopause. This regimen regulates my periods. The pills make me drowsy so I take one right before bed and it helps me sleep better. Also it seems to relieve hot flashes. On the negative side, I feel real bloated after a few days on these pills. : ( 200 mg. 12 days a month F 55 3 years
9/14/2007
 2  To start my period & timing for IUI EXTREME exhaustion, moodiness, depression, anxiety Going on it was a mistake in the first place (I have no fertility problems or reproductive issues), I never needed it and now I have a cyst and my cycle is screwed up. I was on 100 mg x2 a day for two weeks after trying to get pregnant. Now Dr. #2 is using it to fix things by starting my period with it. I take 200 mg before bed. Needless to say I've left the previous Dr. for a competent one. I'm so tired that I'm useless. F 33 14 days
9/7/2007
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 4  post IVF/ICSI transfer very tired, some breast tenderness (nipple area especially), cramping, leg cramps, unmotivated, painful swollen lymph nodes in underarm area, some headaches, alot of dizziness, not so much "moody", but a more "just don't care" attitude. Taking 200mg, 2 times/day, vaginally, morning and evening for first trimester of pregnancy. It is a very potent hormone, with alot of side effects, but if it will help in allowing to carry my babies full-term, then I'm all for it. I thank God for my great female friends right now though because, sorry guys, but most of my male co-workers seem to be driving me around the bend!!! I would be interested to know if anyone else found swollen lymph nodes, that is the only symptom I have not yet come across with someone else. They are like pea sized cysts in my armpits that are extremely uncomfortable. These only just started though in the last day, after about 3 weeks on prometrium. F 36 21 days
9/6/2007
 3  Luteal Phase Progesterone Increase Bloating, twinges in uterus, slight dizziness, pain down backs of legs as if they were bruised (especially my calf area), yellowish discharge, constipation. This is my first month trying Prometrium with IUI and 100mg Clomid. My progesterone level was 4 on CD 13. I haven't been tested to see if it is at a good level to sustain a pregnancy (although I am not sure if I am pregnant yet or not), but we'll see!! Although it is inconvenient (3x per day vaginally) I would continue taking this medication. F 27
9/6/2007
 2  Induce Period after D&C Mild cramping and restless sleep. Low energy level during throughout the day. Had a D&C - 9 weeks pregnant but fetus stopped developing past week five. Seven weeks after D&C no period but crippling cramps - diffcult to even roll over or get out of bed. Doctor put me on 200mg 2X/day for 10 days. Still no period. Had an ultrasound and everything was normal. No blockage, no cysts. Just a very thick uterine lining so can't figure why no period. Not sure if being put on a higher dose will induce a period or simply let nature take it's own course. Don't want to go on birth control because I do not want to mess with my hormones more than is necessary. F 35 10 days
9/4/2007
 3  make my luteal phase longer About 45 mins. after taking I felt a little dizzy. I realized later it was a drunk feeling. I have felt tired and unmotivated all day. I am going to take in the evening now rather than the morning. I was afraid of driving this morning. I have been to many doctors about thyroid problems in 2years. The doctor now is a Creighton Model fertility doctor. She says I have graves disease. My luteal phase was only 8 days last month, hopefully this will make it longer so I can support a pregnancy. F 36 2 days
8/29/2007
 5  Risk of miscarriage spotting, nausea, vomiting (but could have been from the pregnancy) I've had 2 miscarriages so my doctor put me on Prometrium 100mg x2 day from the moment i found out i was pregnant until i reached 12 wks. I now have a healthy boy so i'm guessing Prometrium worked! F 28 6 days
8/27/2007
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 1  Menopause HRT Diarrhea, cramps I posted below about getting cramps and diarrhea from Prometrium. One of my physicians acted like this was either in my head, or I needed a bunch of expensive GI function tests. He suggested I try a compounded progesterone capsule from a compounding pharmacy. I said I would try it. When I asked how they compounded it, I found out that they use lactose. Ding-dong. I am lactose intolerant. The symptoms I got from taking Prometrium were the exact same symptoms I get from drinking milk. I don't know for sure that Prometrium is manufactured with lactose, but it is quite possible given that the compounding pharmacy was going to make a progesterone capsule with lactose. I wanted to post this for anyone who may be lactose intolerant. F 52 8 days
8/25/2007
 3  to build up lining to help conceive Increased intensity of migraines, cramping, Nausea, sleepiness, breast tenderness I take 2 capsules * 3 times a day vaginally. I will continue to take it in the hopes of being pregnant. F 35 4 days
8/21/2007
 1  Trying to get pregnant I have PCOS and my doctor has me on Metformin as well as Armour Thyroid. He prescribed Prometrium as my Progesterone levels were extremely low and I have had miscarriages in the past; I am trying desperately to get pregnant. I started on 100mg of Prometrium and was on it for only 1 and a half months. Side Effects: Yellow/Brown Discharge, rapid weight gain, bloating, severe mood swings, anxiety attacks, crying at absolutely everything, the inability to leave my bed, fear of going outside. All friends and family came to me and let me know I was becoming an "emotional liability" It was terrible and I don't recommend it! My husband and I even discussed divorce. Do not take this if you have anxiety/depression in your family! It enhances all symptoms and fears! F 27 1.5 months
8/18/2007
 4  assist in continuing pregnancy Exhaustion, nausea, irritability I have had two miscarriages over the past year. I had some tests done a couple of months ago and my husband and I are trying again. I was told to take this medication from the time I ovulated until the doctor is able to identify a heart beat in our baby. I have only been on the medication for a week but am hopeful that this time the baby will be healthy and make it to term. The medication has not kept me from doing any of my normal activities, I just tend to take it easy a little more due to the exhaustion and nausea. F 31 6 days
8/13/2007
 4  To lessen uterine bldg (on coumadin BLOATING,WEIGHT GAIN,drunken feeling 45" after dose,sleepiness, fatigue,increased appetite. I was placed on this med. following a uterine ablation procedure. I am on coumadin because I have a mechanical aortic valve, and I was hemorrhaging with each period and needing blood transfusions frequently. The prometrium was said to decrease the thickness of the uterine lining to decrease bleeding. My periods are very light spotting 2 days only now. F 49 4 years
8/3/2007
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 3  IUI/ prevent possible miscarriage BAD hot flashes, sleeplessness at night, but fatigue all day, Very moody- crying at EVERYTHING, frequent urination. I've been on it for 3 cycles of chlomid and one regular cycle before that because of a prior early miscarriage. It seems standard for the fertility center to require it. I take one pill once at night, intervaginally. I find myself being exhausted and wanting to go to sleep until I place it inside, then I am up and having hotflashes, rolling away from my husband and throwing the covers off. I do not even know if I have low progesterone levels but if this helps me to conceive, I'm sure its worth it, though right now it feels awful. F 33 43 days
7/31/2007
 4  heavy bleeding and clotting slight dizzyness and sleepiness after taking - mine is prescribed to take at nighttime - I see why although it is not enough to make me uncomfortable, just slightly fuzzy. I took the first month dose for 12 days starting on day ten of my cycle, and my period was a bit shorter and bleeding slightly less, on second month took medication daily as I had physically felt better for the twelve days on than I had in the past year of suffering with this problem. Going on six weeks without a period and loving it! Feel physically better and nighttime symptoms are getting less noticeable. If at all possible talk to your doctor, stick this one out - it really helped me with my problems. F 44 3 months
7/30/2007

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