PROMETRIUM Reviews (PROGESTERONE)

Average Rating: 3.1 (568 Ratings)

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 ESTROGENS PROGESTINS

 Type: Rx Drug

  

PROMETRIUM  (PROGESTERONE):  Progesterone is a type of female hormone (progestin). This medication is similar to the progesterone that your body naturally makes and is given to replace the hormone when your body is not making enough of it. In women who are not pregnant and not going through menopause, this medication is used to restore normal menstrual periods that have stopped for several months (amenorrhea). Progesterone is also used as part of combination hormone replacement therapy with estrogens to reduce menopause symptoms (e.g., hot flashes). Progesterone is added to estrogen replacement therapy to reduce the risk of cancer of the uterus. This medication is not for use in children. Progesterone must not be used to test for pregnancy.   FDA Approval Date: 1999-10-15 (Sources: U.S. Centers for Medicare Services, FDA)

  

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Key to Ratings: 1=LOW (I would not recommend taking this medicine.)
5=HIGH (this medicine cured me or helped me a great deal.)

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More on PROMETRIUM: Reviews Summary  |  Drug Safety Information

RATING  REASONSIDE EFFECTS FOR PROMETRIUMCOMMENTSSEXAGEDURATION/
DOSAGE
DATE ADDED
 
 2  Induce a period diarrhea, stomach pain, difficulty sleeping through the night, moodiness, dizzyness/off balance I was prescribed Prometrium (200mg at night) when my gyn wanted me to try it for 12 days to induce a period since I hadn't had one in 4 months and only have had 3 in the past year. It all started when I stopped using the Nuvaring. I had very regular periods before I used birth control and while on it. We have been trying to conceive. I finished my last dose 2 weeks ago, and still no period, so I called my doctor and am waiting to see what she recommends to do. The only thing I noticed was a tiny bit of brown discharge and a few cramps 1 - 2 days after my last dose, but thats it. No bleeding. F 24 12 days
11/18/2009
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 1  no periods Dizzness, extreme fatigue, horrible upper back pain, confusion, memory loss, chill I was told to take Prometrium since i was late on my periods. on day 5 i experienced a horrible back pain in the midle of the night. it was so bad I almost went to the ER. Same on day 6. I stopped the prometrium and prefer not having periods and be blaoted than putting my body through so much pain. I still feel a litle dizzy and confused...but i feel better. cant wait for that stuff to completly leave my system. F 36 6 days
11/16/2009
 5  sustain a pregnancy bloating, sleepy, increased thirst, cramping Have had 7 miscarriages in the past Dr put me on Prometrium vaginally on last preg b/c level was 10 and I always miscarried during wk 5-10. Took nightly does ruin your underwear so use panty liners also affect your sex life for a short time till your done using it but I delivered a healthy boy finally! He's 11 mos now and I am 4 wks preg now and on Prometrium again. The listed side effects could be preg related I just pray they hear a heartbeat at my next appt as the drug could delay a miscarriage if one in fact already occured. I have full faith in this drug and hope I NEVER have to go down that dark road again of miscarriage.The only poss side effects in my son are he has red hair and noone in the family does and a bit of a drama queen!!!But is walking and using words already! M 30 12 weeks
11/9/2009
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 5  Menopause No side effects I was suffering severe night sweats, anxiety, restless leg, extremely poor sleep, headaches, depression, hair loss, carb cravings, poor diet cravings...comfort food. I have hypothyroid as well. Have been miserable for 7 years...period stopped and obgyn suggested prometrium and menest. AMAZING! That is all I can say. I have not felt this good in at least 7 years. I sleep like a rock and am functioning better in every way. F 49 60 days
11/7/2009
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 3  PMDD/PMS HEADACHES HOPING THIS WILL WORK HAVE TIRED EVERTHING FOR PMS, I AM HUNGRY/GRAVING FOR FOODS BUT HAVE ALOT OF FRUIT IN THE HOUSE REFUSE TO GAIN WEIGHT, I THINK ONCE YOU KEEP IN MIND ITS THE PIL THAT IS MAKING YOU HUNGRY DO NOT GIVE IN TO IT AND WORKOUT I HOPW WITH ALL THIS THE PIL WORKS FOR ME ALOT OF FINGERS CROSSED F 43 8 days
11/1/2009
 2  Period Regulation First day I was extremely tired all day. Moderate irritability throughout and since I finished taking it (aware of it and it has been pretty bad, but I don't snap at every little thing). I didn't notice an increase in appetite while I was on it, but I have definitely experienced an increase since I finished taking it (over 2 weeks ago). I took Prometrium because I have never been regular and after I tried Depo and stopped using it, I was even more irregular with different colors and consistencies to boot! The Prometrium was supposed to make me have a period 2 weeks after I finished it so that I would start being regular, but it failed at that and things have stayed pretty much the same. One positive mark though: side-effects much milder than with Loestrin24. F 20 12 days
10/29/2009
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 4  symptoms of perimenopause I have terrible night sweats & occas. hot flashes but my biggest complaints were mental fogginess and irritability. After reading other comments on the site about Prometriun and dosages, I decided to start at 100mg. It reduced the frequency of my night sweats 60-70%, hot flashes 50%. Mental clarity improved 50%, but the biggest improvement was my mood. Irritability gone!! So I upped the dose to 200mg to see if I could get more relief from the other symptoms. After 1 month at 200mg there was no further improvement and my mood went to hell!! I dropped back to 100mg and mood greatly improved again. Best way I can describe it is, Prometrium gives me a much longer fuse and my husband is thankful. 100mg is the right dose for me. F 40 3 months
10/23/2009
 1  Eliminate Period (cramps, PMS) Extremely painful nipples, neck/shoulder pain, increased anxiety and irritability to the point of rage, gut pain and bloating, severe fatigue, inability to focus, but the worst: food cravings! Doctors don't have a clear picture of all the effects Prometrium causes. This should never be prescribed to middle aged women who have struggled with weight gain! I've been on this for 1 month and have gained 4 lbs; I was weight stable and losing before this prescription. The side effects are far worse than what the drug was prescribed for. I'm going to start taking Omega 3 Fatty Acids (12,000 mg/day) since I understand it gets rid of severe cramps w/in 3 months. F 47 1 months
10/18/2009
 5  PMS, Postpartum Depression Tiredness, some bloating Be careful about what you read on the Internet. This medication has also saved me numerous times. I have low progesterone in my cycles from PCOS. Had severe postpartum depression with 2nd child, a bout of it over 2 years ago and now with 3rd. Couldn't sleep hardly at all, not even with sleep medications. The prometrium each month, while makes me tired, helps me to feel very calm and sleepy. I love it. I've tried compounded shots and oral prog. but none work as good as Prometrium for me - it is the only FDA approved natural progesterone. Everyone is different so I guess you just have to see for yourself. F 31 2 years
10/13/2009
 2  postmenopause Was taking 200mg prometrium in combination with 2mg of estradiol daily. The good news: after 7 days, the intensity of hot flashes was greatly reduced. Bad news: after 14 days, started developing severe muscle pain on one side of my body and especially bad in the calf of my leg. Decided to quit. F 52 16 days
10/3/2009
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 1  maintain pregnancy (1st trimester) VERY dizzy, headaches, coughing, blurred vision, weakness I began taking this drug at 6 weeks during my last pregnancy which ended in miscarriage. I began taking it this time at 1 day past ovulation. F 33 5 days
9/24/2009
 3  sustain pregnancy dizziness, lightheadedness, extreme fatigue, no energy, moodiness I didn't know what was wrong with me until I read this website and saw all of the same symptoms I had with the others that have taken Prometrium. I have been unable to do anything and barely function for the last week. My doctor confirmed that my symptoms are probably from being 8 wks pregnant and being on 200 mg/day. I have had low progesterone with a couple other pregnancies that resulted in miscarriages, so I'm going to keep on it for another 2-3 weeks, perhaps cut the dosage - hoping to feel better soon, but mainly want the pregnancy to continue. F 41 12 days
9/21/2009
 5  irregular periods I had some insomnia the first cycle. I'm on my 2nd cycle and haven't had the insomnia but last night I had the strangest feeling. I was off balance and the out-of-body experience others mentioned is probably the best description. It was the first time I had taken it and not gone straight to bed. It was probably an hour or so after taking the 200mg nightly dose that this occurred. I also had diarrhea just before these other symptoms and I had eaten something after taking the dose. I'm on my 2nd cycle of 3 cycles. 12 pills every 30 days for 3 months. I've taken 2 pills in this 2nd cycle. F 42 1 months
9/20/2009
 4  prevent miscarriage Sore nipples. Cramps. Bit tired. Bloated. Whitish discharge. Taking Prometrium X2 a day 200mg vaginally. I'm 42years old and wasn't very optimistic because of my age and statistics. I had 1 previous miscarriage a few years ago at 38. My uterine lining was just ok then. I wasn't taking Prometrium at the time. I had an IUI 17days ago and just confirmed that I'm indeed pregnant. I am choosing to stay on it until my 1st trimester is over. It's not a very comfortable to take but i really feel like it's helping. My nipples were sore but that is a side effect of Prometrium. I just found out I'm pregnant. A small clue of pregnancy was that my breast were showing signs of being fuller. No bleeding at implantation but a bit stronger cramps at the time. (used Chlomid n Gonal pre-IUI) I pray this is for real. There's hope, Hang in there! F 42 17 days
9/16/2009
 5  progesterone hormone replacement None- I feel great on it. I take 100 bid. This is reportedly bioidentical progesterone. I take 100 mg bid, a continuous therapy regimen. My estrogen replacement is vivelle dot .050. Both are great and I feel terrific on them. I personally wanted to stay clear of the synthetic progestins and their side effects. F 50 3 years
9/13/2009
 4  Sustain pregnancy Drowsy after taking the dosage at night. Helps me fall asleep quickly but then after 3-4 hours I am spending sleepless nights. I feel depressed and dizzy most of the time. I don't like the drug but it has saved my two pregnancy and I am hopeful it will work this time too. I had 2 miscarriages due to lack of progesterone in my first trimester. My new high risk pregnancy doctor prescribed me prometrium 200 mgs for the entire first trimester. I had two viable pregnancies since. I am pregnant again and taking the prometrium again. However, I spotted recently due to a tear in my placenta so doctor has increased the dosage to 200mgs of prometrium twice a day. F 35 3 months
9/1/2009
 5  irregular periods tender breasts, abdominal cramping and bloating Well my side effects have been minimal in comparison to the benefits it has delivered. I have irregular periods (possibly 3 - 4 annually)and we are trying to conceive. I have a very stressful career and home can be hectic most of the time due to various schedules, children activites and volunteer activities to boot! My stress level has decreased tremendously! I wake up with more energy and ready to take on the day. I was prescribed 200mg once a day taken at bedtime for 10 days. My outlook on life is optimistic and my co-workers have commented on my energy and smile :). Not necessarily a draw back but it knocks me out cold within 20 minutes and I sleep soundly. Sore breasts and the first five days, cramps felt like contractions (days 7 - 10). Finished 10 days as prescribed yet 14 days later still no period. I was told my period should start within 14 days of the last dosage. So, I am back to the lab for more blood work. If it was not for the fact we are trying to have a baby, I could take this medication every day! F 39 10 days
8/25/2009
 5  Pmdd, heavy and painful periods Breast swelling, headaches I love this drug. It saved my life. They put me on head meds for two years trying to"fix " me. I kept telling them it was hormones, not head problems, that were causing the paranoia, stress, anxiety and phobias that were developing so that I could not leave my house for two weeks out of the month. I was such a mess and out of hope before I flew to maine (from the west coast) to see a doctor that specialized in female probs). I was suicidal from trying so many meds that just made everything worse. The prometrium changed my life. I can function normally and realize when the mood shift happens (ovulation) it's time to start taking two pills in the morning and two at night. Amazing. I can live with the sore breast (I had to invest in some serious bras though) and the head aches (suboxicipital tension). A little physical discomfort is well worth the internal relief. I've been taking it over a year and love it. F 39 1.5 years
8/21/2009
 3  irregular, heavy bleeding Severe weepiness/moodiness, constant pain in back and sharp pain under ribs on right side (more severe at night after taking my pill). My inability to fall asleep increased and tossing/turning increased. It did straighten out my irregular bleeding and lessened the heaviness of the bleeding, but not sure if the trade off of wanting to do bodily harm to others is worth it. Will be looking for other treatment options. F 38 28 days
8/11/2009
 2  Difficult, Irregular Periods Extraordinary leg pain, monster cramps, weepy, clingy, zero energy, increased appetite. I was told to take it at night because it was supposed to make me sleepy, but I didn't notice that it did. It seemed to me that my insomnia was worse. I had increased appetite, but nothing I would eat seemed to satisfy my - it was never the "right" thing. I would cry at the drop of a hat and the next moment be so angry I wanted to throw something. I was under the impression that hormone therapy was supposed to make these issues BETTER not worse. Not impressed. I am taking it for 10 days beginning 10 days after the first day of my period. I have only been through one cycle of it, but if this time around is no better, I'll be asking for something different. F 39 10 days
8/10/2009

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