LUPRON DEPOT Reviews (LEUPROLIDE ACETATE)

Average Rating: 3.0 (783 Ratings)

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 ANTERIOR PITUITARY HYPOTHALMIC FUNCTION ANTINEOPLASTICS

 Type: Rx Drug

  

LUPRON DEPOT  (LEUPROLIDE ACETATE):  Leuprolide is used to treat advanced prostate cancer in men. It is not a cure. Most types of prostate cancer need the male hormone testosterone to grow and spread. Leuprolide works by reducing the amount of testosterone that the body makes. This helps slow or stop the growth of cancer cells and helps relieve symptoms such as painful/difficult urination. Talk to your doctor about the risks and benefits of treatment.   FDA Approval Date: 1989-01-26 (Sources: U.S. Centers for Medicare Services, FDA)

  

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Key to Ratings: 1=LOW (I would not recommend taking this medicine.)
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More on LUPRON DEPOT: Reviews Summary  |  Drug Safety Information

RATING  REASONSIDE EFFECTS FOR LUPRON DEPOTCOMMENTSSEXAGEDURATION/
DOSAGE
DATE ADDED
 
 1  Adenomyosis Ataxia and falling, loss of consciousness, depression, insomnia, extreme hypertension, brain seizure, fibromyalgia symptoms, rheumatoid arthritis symptoms, 30 lbs weight gain, complete inability to function. Even after stopping Lupron I am now dealing with the same side effects. This drug needs to be taken off the market. Much important information regarding the drug is not made known the patient in particular that it is a chemo drug with steroids. F 44 4 months
Injection 1X M
4/26/2015
Email
 5  Endometriosis Minor hot flashes (actually welcome during cold winter!), BAD headaches 2-3x/month, achy joints- esp feet & legs, minor mood swings, weight gain (holidays didn't help!), brain-fog/forgetfulness, but most natably, NO PAIN FROM ENDOMETRIOSIS! Though a different dosage, I took Lupron many times from 1998-2007 for IVF. I have 4 children of my own & also 2 surro-babies :-) I don't recall any major side effects then. This time around is different! I am experiencing increased joint/muscle pain-esp in my legs-and found this site looking for answers. There are some pretty scary posts here! Though I have some serious side effects, I am assuming they will resolve once my 6-month treatment ends. They are all worth not having the pain of endometriosis every month! I have been thinking that gluten is making these symptoms worse, so am not entirely convinced that Lupron is the cause. F 42 4 months
11.25
4/5/2015
Email
 5  fibroids hot flashes. Fibroids and bloating greatly (although temporarily, I understand) reduced. Period stopped; no spotting. AWESOME stuff! F 47 6 months
3.75 1X M
3/11/2015
 4  Fibroids n endrometris Hot flashes mood swings stiffness in fingers I took shot every 3 months totally 3 shots towards the end my pressure went up every moring my fingers be stiff F 46 3 months
2/2/2015
 5  Endometriosis Hot Flashes, Night Sweats, Mood Swings, Fog As bad as the menopausal symptoms are it greatly helped the pain F 24 1 years
3.75 mg
1/31/2015
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 5  hospital none of them it helped me alot no pains nothing cz every month i was in pain thank god and the doctor F 30 1 months
30by2
1/27/2015
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 4  uterine fibroids I've been on lupron for two and a half months now. It seems to have helped to put an end to my constant bleeding and allowed my body to "catch up" on blood so I'm no longer anemic. Yay! I have noticed some pretty crazy mood swings, night sweats, hot flashes and worst of all joint aches. I over all feel better and am anxious to see if the fibroids have shrunk enough for my Dr. To remove them without another envasive surgery. I would hope anyone who may be put on lupron can have an honest and open discussion with their Dr about the drug and it's side effects. I have read that being on lupron for long amounts of time can cause bone loss and other side effects down the line. If you have worries talk to your Dr openly and if you still have reserves get a second opinion. I'm happy it has seemingly helped me with my fibroids and hope others can benefit from it also. F 31 3 months
11/11/2014
 1  ENDOMETRIOSIS Depression,Joint Pain, Memory Loss,BiPolar Disorder and Osteoarthritis. F 50 6 months
10/27/2014
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 5  fibroids Night sweats. I had a fibroids measuring 5cm. After 2 days of my first shot. Too mach bleeding then my hgb drop to 7.no problem at all before that I'm taking ferrous n continue it. Then I go for ultra sound it measures 4.4cm. On my second shot the fibroids becomes 2.2cm. Done my 3 shots n the fibroids still degenarating. No heavy menstral period at all. During the medication I indulge my self in gym. Do my work out 3 times a week.watch my diet high in fruits n vegetables my soul source of protein was dairy products.no red meat at all.1 liter of water/day. Lupron depot affects our hormones..so a great suggestion is have a physical work out n healthy diet will help the patient to prevent the drastic side effect of the medication. Healthy lifestyle together with medication n prayer..positive results. F 38 3 months
10/16/2014
 3  Prostate Cancer Many side effects: mild headache, breathing difficulty, testicle/prostate swelling, urinating problems, hot flashes,lousy day to day feeling, loss of body strength and libido,blurry vision at times, not as steady in balance, throat-thyroid feels different when swallowing or moving head forward. Slows and affects memory. Drug is working to bring PSA and testosterone down but at a great physical cost. If there was another way out of this, I would take it for the Lupron drug seems to severely affect many body functions taking them from a normal to abnormal state. Many side effects: mild headache, breathing difficulty, testicle/prostate swelling, urinating problems, hot flashes,lousy day to day feeling, loss of strength,blurry vision at times, not as steady in balance, throat-thyroid feels different when swallowing or moving head forward. Slows and affects memory. Drug is working to bring PSA and testosterone down but at a great physical cost. If there was another way out of this, I would take it for the Lupron drug seems to severely affect many body functions taking them from a normal to abnormal state. M 67 2 months
1X M
9/7/2014
 1  endometriosis Lupron ruined my life!! At first I was all for feeling better but I'm regretting ever letting that needle touch my skin. I started lupron after the birth of my second child. I had tried 17 different birth controls that could possibly help or hinder the pain from the endometriosis the one that did help got recalled. I figured wth might as well give it a try. Worst mistake ever! The doctor did not give me a pamphlet just told me of the hot flashes. The first week the hot flashes came and went all day every day. I then started feeling dizzy and faint. My energy was gone. By week 6 I started having signs of a uti so got azo and prescribed meds little did I know it wasn't a uti it was a side effect. My kidneys began to hurt. It hurt to breath it felt as though I had an elephant sitting on my lungs.Then my whole body started to weaken to the point I couldn't open a jar that had previously been opened. My muscles and bones ached it hurt with every little movement. My body then began to swell(this side effect is still with me it's been several months since I've had my last dse) my ankles swell the second I put them on the floor each mornings the rest of the body parts soon follow. I had lost all interest in sexual activity.I soon got depressed I felt worthless couldn't even play with my kids. My marriage got rocky bc of how I felt. I started getting bumps under my skin on my neck, shoulder and back and it was very painful. My primary care physician said shingles but i don't think F 26 3 months
1 shot
7/14/2014
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 3  ovary pain I'm finishing up my first month of this shot. I had gotten this shot due to A LOT of pain. I have had a tubal plus an ablation. I haven't had a period in 3yrs. My dr recommend it to me. Since my shot my pain has STOPPED but I've cried more than ever, hot flashes and the one I hate the most is I've been having dizzy spells BAD F 28 3 months
1shot 1X M
7/7/2014
 5  Uterine fibroids None. F 37 2 months
3.75
3/17/2014
 1  Endometriosis I ended up with a severe depression and got suicidal two weeks after starting treatment because my gynecologist forgot to mention that depression is a known side effect especially in patients with a history of depression. In my case it meant that the nightmares I endured during my PTSD came back. After about four weeks the pain in my entire body got so severe that I had difficulties urinating. At that time I also felt exhausted and gained so much weight that my clothes did not fit anymore. Because I was mentally unstable it took me six months before I was able to drag myself to my GP ( I didn't want to go to my gynecologist anymore because of the mistake she made) who immediately checked my blood and it was then that I was diagnosed with hypothyroid. At that time my GP thought that the pain in my body was a side effect of untreated hypothyroid. Therefore it was necessary to first start medication before further tests could be done. After four months on thyroid medication my GP referred F 38 1 months
3,75 mg 1X M
3/6/2014
Email
 1  Prostate My dads urologist administered Lupron Depot . My dad had prostate cancer 20 years ago and his PSA level was slightly elevated in October. His urologist never warned us of the side effects an elderly person might encounter on Lupron Depot so we were in complete shock when dad suffered a major stroke. We are very upset ... Dad was very healthy for an 83 year old, going to aerobics class 3 times a week..now he can't walk or use his left side at all and he is confined to bed. If we would of known that this drug caused strokes, we would of never agreed to use it! M 83
1X day
3/2/2014
Email
 1  endometriosis Never ever will I agree to this again its been living hell on my 5 treatment and bout lost everything the pain is god awful so weak its a nightmare F 26 6 months
37.5
2/11/2014
Email
 4  shrink large fybroids I was prescribed 6 injections/1 per month. I am on number 3. My irregular bleeding did not stop right away after the first 2. It wasnt really period blood it was old blood. That has finally stopped..THANK GOODNESS! I was due for a period on the 18 and it has not came yet so i feel this is really working. Im on a lower dose than most but its working.I have always had a temper but contribute it to the stress of having re-occuring fybroids and bleeding throughout my adult life. Bledding so much has caused me to be moody and mean...I feel better knowing that Im finally on the road to being done with these issues so besides the night sweats, and my vision is kind of bad now I feel wonderful and im glad im taking the shots. I can actually lay on my stomach now! Im also fitting into shirts that iused to look pregnant in. The shots are definately shrinking the fybroids and that is such a blessing. My whole goal is to shrink the fybroids so when i have surgery i dont have to have a hysterectomy and i can have a child. My fybroids made me look 8 months pregnant. I have noticed that i have lost weight and im getting some acne patches on my buttock where the injection is put but if i have to go through this to not bleed for 2 months straight and eventualy save my uterus and have a child..ill take it! Im o.k...i do have a quicker temper now but i just keep telling myself "the medicine is working so stop cussing people out and smile"...lol Im on shot number 3...i have 3 more to go F 37 6 months
3.75 1X M
1/25/2014
Email
 3  Endo Lost of weight of 8lbs, hot flashes every half n hour, night sweats, lost of memory, ensonmia, lost of vision, mild case of joint pain. Depression, crying all the time. Mood swings. I have been done with the Lupron shot for two months. Still no period. I feel sick to my stomach all the time, and I can't get enough sleep ever. I am wondering when it will go away and I can be normal. During the Lupron shot, the cycle stopped right after one week of being on it. The sym slowly starting taking over my body each month. The Doc did not tell me about loosing weight or lost of vision or memory loss. Was very scared that happened to me. I lost my job because of sym was taking over my body that I couldn't control. Luckily I found another job. I don't think I would do this again. F 30 3 months
3.75 1X M
11/7/2013
Email
 1  endo neck swelling burning,feels like my throat is hot and water does not quench, headaches, hotflashes,cyst blewup, moody, blurred vision, chest pains, fatigue...all from 1 shot..I think I had a reaction to the shot F 46 1 times
1X day
8/11/2013
 1  Endometriosis, Fibroid tumors Suicidal thoughts Heart Murmur Hot flashes Urinary Incontinence Insomnia Headaches I was never told that this is chemotherapy, nor was I advised of any side effects except for hot flashes. I would not recommend to anyone! F 42 3 months
3.75 1X M
7/31/2013
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