LUPRON DEPOT Reviews (LEUPROLIDE ACETATE)Average Rating: 3.0 (783 Ratings)Filter ResultsCompare LUPRON DEPOT with similar:
Type: Rx Drug
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More on LUPRON DEPOT: Reviews Summary | Drug Safety Information
| RATING | REASON | SIDE EFFECTS FOR LUPRON DEPOT | COMMENTS | SEX | AGE | DURATION/ DOSAGE | DATE ADDED |
| 4 | Endometriosis | Mild headaches off and on. | I figured I would add my own experiences since everything I read is so negative. I almost didn't go on Lupron because I had read horrible reactions people were having but decided to try it anyway. I'm on my 2nd Lupron injection and have to say (other than a few mild headaches)it has been a good experience overall. I had been put on birth control for several months before this and felt horrible. I think there are some people that just can't handle the pill and I'm one of them. So after going through all of that I was worried about Lupron but I actually feel better than I have felt in a long time. I'm no longer on the pill which made a HUGE difference. I'm back to exercising and really have had no complaints about this. I won't know about how well it worked on my Endo until my treatments are over but I'm very optimistic. Just remember to take calcium supplements while on Lupron. | F | 31 | 2 months 1X M | 5/22/2010 | 5 | Severe Endo | Hot Flashes, Vaginal Dryness, Weight Loss, | I have to believe that comment site such as this one are mostly populated by those who have had negative reactions to this injection. I would like to share my experience with those who feel as if they are at the end of their rope. My OBGYN - a very very well educated doctor suggested after my diagnosis with endo that I try this injection on a 3 month bases with add-back medication and a VERY high dosage of calcium from the start. He was very up front with me that there WOULD BE SIDE EFFECTS. Indeed there were side effects, hot flashes, vaginal dryness, weight loss, and a few night sweats that decreased greatly after we increased my add-back dosage. I took my second 3-month shot and was very content with the side effects. I will take a few hot flashes over the pain of a period any day of the week. I have been off of Lupron for over a year now and have just started having painful periods again, but only on my first day. My doctor and I are discussing my options at this point as Lupron is not *approved* for longer than 6 months of treatment. For those looking to bide some time before having children, or making that decision I would say go for it - talk with you doctor honestly and be honest. | F | 27 | 6 months 1X O | 5/21/2010 | 2 | Endometriosis | Few hot flashes, Easily irritable/extreme moodiness, forgetfulness, nausea/diarrhea, difficulty sleeping, aches/pains to joints. | After attempting to have a child after 5 years and seeing multiple gynos, I went to a new one almost 2 years ago for pelvic pain and infertility. I had a diagnostic lap with a D&C done last summer, confirming moderately severe endo. In November, I started on the Lupron to "control the pain and buy me some time to have children", so the dr. said. He also put me on Norethindrone to help control hot flashes. The first 2 months weren't the best:feeling run down, depressed, irritable, with only a few hot flashes, unable to fully enjoy the holidays. Then he put me on Prozac for difficulty sleeping and depression. For the 1st month immediately following, I was fine. Smiling, wearing colors again, socializing. Still easily fatigued, but workable. Around the End of month 5, the moodiness picked up again and has been steadily increasing (or so I'm told by my husband and boss). This is month 7of9, and am not going to go through with the last 2 shots! My coworkers have complained about this change to my boss, I can't go out and socialize, get over-stressed about the silliest things much more easily. At this moment, I find myself thinking that I'd rather lose my ovaries and my chance for children than to continue through this suffering. | F | 27 | 7 months 3.75 1X M | 5/16/2010 | 4 | fibroids | Vaginal dryness and hot flashes, otherwise I feel fine. My energy level in increasing. I feel extra hungry however. No weight gain yet. | M | 45 | 2 months 1X M | 5/14/2010 | 4 | sever endometriosis | vaginal dryness, decreased sex drive, craziness | I took this med for 7 months and didn't experience anything until my last injection. I became very hormonal and bitchy. I got night sweats and hot flashes, but those went away as soon as they came. I felt very paranoid and was very bitchy towards my boyfriend especially. I spotted a couple times, but only for a day. It helped out alot with the pain, so I feel like it was worth it! | F | 23 | 7 months 1X O | 5/10/2010 | 1 | fibroids | Extreme mental depressions, up and down emotions. Knee, lower leg and hip pain to the extremes. Headaches and general ill feeling. Nausea, vomiting, constipation and diarreah. Not daily but enough that it was uncomfortable. Weight loss, lack of appetite. | I was told that I should take this shot and it would shrink my fibroids and help in excessive bleeding and then I would be able to get robotic surgery. They said after surgery that they couldn't do the surgery with robotics, since the fibroids were too large and there was too many, originally had two, they said ended up with 8. A normal uterus weight about 90 gm, mine was 854 gm, after 3 months of Lupron. With the extreme cost of this shot, I feel it was not worth the pain, suffering and mental anguish! I could have had my hysterectomy three months earlier! And saved alot of money! The lack of bleeding was the only advantage of this shot. Don't do it, if you have excessive fibroids, or you have had them for a extended period of time | F | 56 | 3 months 30 mg 1X M | 4/24/2010 | 1 | Endometriosis and ovarian cysts | Severe hot flashes, Night sweats, dizzy spells, faintness, grogginess, insomnia, nausea, vomiting, constipation, migraines, itchy dry skin, initially a yeast infection which passed after about 3 days, vaginal dryness, dehydration, feverishness & chills, achey arms and legs, initial weight gain/bloating, irritability and crankiness, shakiness/trembling on occasion...SEVERE RASH when my skin is exposed to the sun. | My doctor convinced me to try these injections for 3 months, as an alternative to surgery. It did NOT HELP, in fact it made me feel worse. I've only had the first injection and refused to go back for the second & third doses. It's been 2 1/2 months and I am still suffering from the majority of the side effects every day. Furthermore it did NOTHING to help control my endometriosis symptoms, in fact they are much worse now. I was better off before I got the shot. I really regret letting my doctor talk me into this and wish I had just opted for another lapro or even hysterectomy. DO NOT take this medication it is awful, and not worth the expense! | F | 41 | 1 months unknown 1X M | 4/18/2010 | 1 | Fibroids and endometriosis | Extremely tired all day everyday and only really able to go to work and back home, get gasoline and barely able to even grocery shop I am so tired; not able to exercise, of course; muscle fatigue; feeling I will faint several times per day; severe migraines; insomnia; not feeling present; mood swings; bleeding | I took this drug once on 2/15/10 due to my ob/gyn and her nurse strongly recommending this drug to shrink my fibroids and endometriosis prior to surgery in July, and I had doubts but I trusted them, and taking this drug was one of the greatest mistakes of my life. Now, my ob/gyn is not being honest and denying that the lupron is causing all the severe side effects that I have never experienced prior to this injection. My ob/gyn also had the nerve to tell me that my medical record shows that I received 3 lupron injections in 2006 prior to having surgery to remove fibroids only (no endometriosis at that time), and I was absolutely shocked and told her that my medical record has been falsified because I HAVE NEVER RECEIVED THIS DRUG PRIOR TO 2/15/10. Her response was shock, silence and stating she does not know what to say. I believe she is just trying to protect herself from a potential lawsuit from me. She and her nurse both adamantly told me the worst side effect would be hot flashes and the progesterone pill I would take each day would stop that, but they both lied. The worst side effects are what I previously mentioned and those symptoms have not diminished-- AT ALL. Of course, I absolutely refused to take another injection, and I ceased the progesterone pills because ironically and horribly those pills only exacerbated the symptoms I was already experiencing. I saw my ob/gyn on 4/2/10 and she said I should not have any side effects now since I only received one inject | F | 39 | 1X day | 4/5/2010 | 2 | Endometriosis and cysts | EXTREME fatigue, hot flashes, night sweats, appetite increased | My doctor told me of no side effects, and I started bleeding again, i already had my period and am not supposed too..but now i am bleeding AGAIN. My docotr did a laporoscopy and had no info except that i had endo....i mean i can't do anything because my doc is a moron. | F | 21 | 9 days 1X M | 3/31/2010 | 1 | to shrink fibroids prior to removal | Awfull !!!! sleepless nights extreme hot flashes frequent trips to the loo , tiredness . | had 3 horrid months on this injection, severe hot flashes at times 3 an hour !! lots of peeing 3-4 times a night sleepless nights,only bonus was no period after the second month, went for surgery and the fibriod hadnt shrunk any, so was a waste of time !!!!!!!!!! would definatly not have any more, if had read more about it may not have bothered at all . | F | 42 | 3 days 1X M | 3/28/2010 | 3 | endometriosis & fibroids | 1st-anxiety at GETTING the shot. :) soreness at injection site for a day or two. within days i felt the hormonal changes. have been extremely tired and lethargic.migraines have increased in frequency and duration.still have my cramping & sharp pain from the fibroids.bled for 17 days.on the 18th i stopped bleeding and proceeded to have a 'psychotic episode' at work-assuming this was a hormone fluctuation as i typically never get moody from hormones. massive hot flashes and night sweats, which contribute to my insomnia. have a general 'foggy' feeling. good news, my skin hasnt looked this good in years so im having the adverse acne effect. :) i've gained at least 5lbs in the last few weeks and if i bloat anymore, i will explode. | i have hopes that these side effects will diminish...the dr said he will not do a hysterectomy on my because of my age even tho i have a 16 year old and will NEVER pro-create again. birth control has never helped, and has only made me insane w/ mood swings. if i experience the same on the 2nd shot (male dr. recommended 3 shots and then surgery if it helps) im done with this. i hope to all that is holy i dont have long term side effects. | F | 38 | 18 days 1X M | 3/25/2010 | 2 | adenomyosis and fibroids | just very tender at injection site for several days | I took the shot on March 1. I was diagnosed with adenomyosis and fibroids. I was hoping to have tumor ablation but the only treatment for adenomyosis is to remove the uterus. I am going in for a supracervical hysterectomy in June. We can't do it any sooner since I am anemic and the fibroids are large. The lupron shot was to shut down my ovaries so that I would stop bleeding and build my blood up and hopefully shrink the fibroids. I have always had heavy periods and they have gotten worse over the last few years. On the 22 day into my cycle I started bleeding, by day 2 I was flooding every hour changing a super plus tampon and over night pad. I am on my third day and it is finally letting up some. Hopefully I will stop soon and not bleed the next two months. I need to be stronger for surgery. I know spotting was a possibility but this was awful. I started taking vitamin k and vitamin d drops. Will let you know how it progresses. It was an awful expensive mistake if it doesn't work. Thank God my insurance paid for it. Other than that I can't say that I notice any side effects. Hope it works better for others. I was so looking forward to giving the rest of my tampons to my daughter. I ended up having to go buy more. | F | 48 | 11.25 1X day | 3/18/2010 | 5 | Fibroids | side effects were light acne on my chest, fatigue, tender skin in genital area. lower back pain in place of menstrual cycle. | side effects were only experienced when i did not take the norethin ace 5mg daily. this is a recommended therapy that your doctor should prescribe along with lupron for fibroid treatment. lower back pain did not go away with regular use of norethin, but was resolved with extra strength tylenol. i have regular migraines, and was not out of regular frequency during lupron treatment. finished my 90-day cycle and planning ab-myo at the end of the month. this drug effects EVERYONE differently. i read the horror stories on this site before taking lupron and almost changed my mind. please do not be scared off by someone who had a bad experience. if a few months of inconvenience is worth the chance to have a better surgery and be pain free, healthy, and increase your chances at reproduction, it's a small sacrifice. discuss all of your concerns with your doctor and family to make the best decision for yourself. | F | 37 | 90 days 11.25 1X O | 3/8/2010 | 1 | Fibroids, before hysteroscopic myo | Abdominal swelling or bloating. Not weight gain - I am only 92 pounds! - but rather seems to be PERMANENT water retention. The bloat occurred immediately after ONE Lupron shot during the estrogen flare phase, then diminished during the brief menopausal phase, then returned suddenly five weeks after I took the shot, as my estrogen levels returned to "normal". Seven months later I fear that my pituitary gland is permanently damaged. I am seeing an endocrinologist who is mystified by such localized bloat. My lower abdomen has an uncomfortable swelling about the size of a baseball and this has led to depression, anxiety, and high blood pressure. Also insomnia and kidney stones which I attribute to the calcium I took while on Lupron. This nightmare was totally unnecessary and I was the picture of health and fitness before I took this shot. If anyone has seen their abdominal bloating eventually subside, PLEASE PLEASE email me here and tell me how long it took and what, if a | DO NOT TRY THIS DRUG EVEN ONCE !!!!! YOU WILL NEVER FORGIVE YOURSELF. It is NOT a cure for fibroids or endo. If your doctor suggests this drug, run like hell and find a better doctor!!! The whole medical community will deny Lupron caused your problems but we know the truth. We MUST all work to get this drug off the market. | F | 45 | 3.75mg 1X day | 2/27/2010 Patient History | 3 | Fibroids, heavy bleeding, anemia | Extremely emotional, lots of crying, mood swings, hot flashes, weight gain, cravings for sweets, 2 weeks of heavy anxiety, irritability, daily mild to moderate depression, confusion, have become very forgetful, haven't lost my job yet but every day seems to be a struggle. | I'm also taking uņa de gato and guanabana leaves teas from Peru to shrink the fibroids. I experienced an abnormal period on Jan 11th. I lost 1/2 of my blood in 2 days which was caused by the fibroid(s) I didn't know I had. I have at least 2 submucosal fibroids: the largest one is 6.5cm long in the front of the uterus and the second one is 3cm big on the back of the uterus. There are other smaller fibroids in the uterus but not significant in size at the moment. My doctor believes that the 3cm fibroid is the one that caused the unstoppable bleeding which made me anemic. In two days of heavy bleeding Jan 11th-12th, my hemoglobin count dropped to 6.4 and I received 2 points of blood transfussion to bring it up to 8. I also had surgery on Jan 13th to remove the blood clots which were preventing the uterus from shrinking. After that surgery, I was given shots of methyrgene/pills to shrink my uterus prior to the 11.25mg 3 month supply lupron depot shot. One month since Jan 11th, my hemoglobin reading has gone up to 12.2 which categorizes me non-anemic. I have an ultrasound visit at the end of March to determine if all fibroids are less than 3cm to do the next internal surgery to remove them. Otherwise, open surgery will be required. Due to the severe side effects I experienced for about 2 weeks between Jan 30th and Feb 11th, my GYN recommended me not to go for the 2nd shot, but I might object to her decision as long as lupron depot shows being effective in the Mar | F | 32 | 3 months 11.25mg 1X O | 2/22/2010 | 1 | Fibroids, Heavy Period | hot flashes, hot flashes and night sweats during sleep, muscle & joint weakness & pain, extreme fatigue, sadness, itchy skin, craving for chocolates so for the past week i've been eating a lot, lot of chocolates | Two days after I took the depot lupron shot, I had an allergic reaction..had difficult of breathing and swallowing, feels like my throat is closing...i can't even swallow my saliva, I panic and my husband took me to the emergency room. I don't recommend this to anyone, this is the worst thing i have done.... | F | 43 | 3 weeks 1X day | 2/21/2010 | 5 | migraines/2cifhystterectomywillhelp | hot flashes, hot flashes and night sweats during sleep, one period and 14 days of spotting with first injection, irritabilaty- no pain at all | I have had cyclic migraines for over 15 years - after visiting a very renowned headache clinic, top notch nuerologist, pain management dr's etc.. no one would listen to me. I knew my periods where the source of my migraines and have been asking for a hysterectomy for years. The dr's. would just blow me off citing "there is not enough evidenc to prove that a hysterectomy will cure your migranes. After being chronically anemic for years, my hemotalogist and ob cunsulted and FINALLY my ob decided to put me on Lupron. He indicated that if the Lupron worked and eliminated the migraines, he would then preform a hysterctomy. After my first shot, I had a period a bled for approx two additional weeks. It wasn't until I had my second shot that I've had substantial success. For the first time in years I did not have to visit the er to get a shot af narcotics for out of control migraines! They have greatly reduced to just a few, very low on the pain scale and the fact that I have a sinus infection makes me wonder if that may be the culprit. BONUS: I have lost over fifteen pounds without trying or changing a thing and the weight is still coming off - I know each body reacts differently, but for someone who has suffered almost half her life with debilitating migraines-I think it is an answer to a prayer, L.B. | F | 43 | 2 months 7.5 2X M | 2/12/2010 | 3 | Anemia due to long term bleeding | Night sweats, mood swings, loss of sex drive, hot flashes | I am now 21 years old, when I was 17 I had been telling my OB GYN that I could not stop bleeding and he kept telling me it was normal considering my recent change in birth control. I woke up one morning and my left arm was numb so I called the doctor. After seeing him I had to go to the hospital for further testing..turns out I had a blood clot and an aneurysm so I had to be medflew to a bigger hospital for emergency surgeries. After surgery I found out that I was suffering from anemia. A specialist OB came in and told my parents that they had to stop my menstrual bleeding and that these injections were my only option. I felt horrible not only were the surgeries bad enough but then I had these side effects on top of being in ICU for weeks. That wasn't even the begginning. I ended up taking these for almost a year and about 5 months after I finished I noticed I have vaginal dryness and no desire to have intercourse. I called the doctor and asked the nurse she just acted like I was dumb and said yeah that's a side effect and you'll just have to go buy some lubricant. I mean I am young and I should not be having to worry about this. After reading this post I actually feel like I'm not alone. Its just so frustrating and I'm so moody. What can I do to keep my relationship strong? How can we make someone understand? | F | 21 | 1 years 1X M | 2/7/2010 | 2 | Endometriosis | Muscle & joint weakness & pain, night sweats with insomnia, decreased libido, extreme fatigue, sadness. | First few months were ok, but then my body aged over night. I have 2 moths to go to complete a 6 month treatment & am considering not finishing it. I have stage 3 endometriosis which was diagnosed after 2 years of infertility treatments, including 2 failed IVF cycles. The side effects I have experienced from this drug are constant vs the temporary pain of the endo around my period times. I would rather suffer that pain than deal with these side effects any longer. | F | 38 | 6 months | 1/24/2010 | 4 | ProstateCancer | Hot Flashes. Total loss of libido. Unable to get eractions | Been on Lupron for 5 months. Second shot hurt so bad could hardly walk for 3 days. PSA went from 38 down to 2.4 so it is working. Going to go intermittent to give body a chance to recover. Trying to keep from surgery/radiation if possible. | M | 79 | 5 months | 12/23/2009 |