Reviews for LUPRON DEPOT

67 ratings: (side effects include muscle)

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 ANTERIOR PITUITARY HYPOTHALMIC FUNCTION ANTINEOPLASTICS

 Type: Rx Drug

  

LUPRON DEPOT  (LEUPROLIDE ACETATE):  Leuprolide is used to treat advanced prostate cancer in men. It is not a cure. Most types of prostate cancer need the male hormone testosterone to grow and spread. Leuprolide works by reducing the amount of testosterone that the body makes. This helps slow or stop the growth of cancer cells and helps relieve symptoms such as painful/difficult urination. Talk to your doctor about the risks and benefits of treatment.   FDA Approval Date: 1989-01-26 (Sources: U.S. Centers for Medicare Services, FDA)

  

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Key to Ratings: 1=LOW (I would not recommend taking this medicine.)
5=HIGH (this medicine cured me or helped me a great deal.)

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More on LUPRON DEPOT: Reviews Summary  |  Drug Safety Information

RATING  REASONSIDE EFFECTS FOR LUPRON DEPOTCOMMENTSSEXAGEDURATION/
DOSAGE
DATE ADDED
 
 1  Breast cancer Briefly? Lol. Athlete to being on disability. Debilitating bone and muscle pain, hair loss, tooth and bone loss. Chronic UTI; severe accelerated DDD and DJD; central obesity, 100# weight gain; severe short term memory loss; inability to retain or memorize the simplest things; tachycardia; Lupron accelerates the aging process overnight by approximately 25 yrs. Don't believe me? I dare u to take one shot. My problems only got worse, nothing improved. F 50 5 days
Varied 5X M
6/19/2021
 4  Endometriosis Hot flashes, muscle spasms and stiffness, mood swings and loss of libido. It has helped 95% of my endo pain. F 34 2 months
2x 3.75 1X M
5/2/2021
Email
 1  recurring prostate cancer insomnia leg pain 20 lb weight gain in mid section grew breast testicals shrank memory and cognitive decline head aches unbeliveable fatigue muscle loss hot flashes ears ringing no sex drive very emotional crying suicidal thoughts loose stool six times a day I was not told about the side effects or given anything to read blood pressure went up 20 points also It was like being on a plane about to crash and pilot didnt say brace for impact there was no monitoring during the six months I was on it I would never take again rather die M 61 6 months
? 1X O
3/16/2021
Email
 1  Endometriosis Never ending side effects. I had this drug injected in me with hopes it would stop Endometriosis spreading. It caused me to eventually have to give up my career as a child psychologist to being totally disabled with Endometriosis growths and fibromyalgia, RA, muscle spasms and ptsd. It never leaves your system and attaches to your dna and changes it. I miscarried at 16 weeks after my last injection 4 months before I was pregnant. I’ve never been pregnant since then in 1995. I am now on stron pain meds just to function and spend many days in bed. Do not take this drug poison under any circumstances. It will ruin your health for life and not cure what the docs say. They get paid off to prescribe it by big pharma. Do not take this medicine!! It’s pure poison. F 49 6 months
150mg shot
2/20/2018
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 4  Endometriosis/adenomyosis Joint/muscle pain and weakness. Awful hot flashes, multiple times per hour. Sleepless nights from insomnia and constant hot flashes/night sweats. About to go on climara patch to hopefully counteract. Love not having pain, but would love to go 15 minutes without getting soaked in sweat! :(. Bled for two weeks, approximately 2 weeks after the injection. Taking for pain, also to increase success of IVF. F 37 3 months
12/22/2016
 4  Endometriosis/adenomyosis Joint/muscle pain and weakness. Awful hot flashes, multiple times per hour. Sleepless nights from insomnia and constant hot flashes/night sweats. About to go on climara patch to hopefully counteract. Love not having pain, but would love to go 15 minutes without getting soaked in sweat! :(. Bled for two weeks, approximately 2 weeks after the injection. Taking for pain, also to increase success of IVF. F 37 3 months
12/22/2016
 3  Uterine fibroids The day I received shot I had hot flashes and chills and my arse was sore and burning for a week,4 weeks later I still have hot flashes and chills. I've also been spotting since getting shot. One week later I felt like I had the flu, my whole body hurt and had burning sensation in muscles and in kidney area also very tired.I also experienced burning sensation in both nipples, it felt like someone took sandpaper over my nipples.4 weeks later my bones still kinda ache, I'm still spotting and I also have vaginal dryness, lack of sex drive. I also see things in peripheral vision. Didn't have that before. Also some forgetfulness.I also get weird shooting pain sensation in head. My mood after shot, little things would set me off. Kinda feel emotional at times. I don't like the side effects but it did shrink my fibroid and will soon have surgery to remove it and then hopefully this nightmare will be over and my periods will be normal and not Niagara falls. I had one injection and I'm not sure I would get the second one if it was prescribed but I'm sensitive when it comes to medication. The side effects are manageable and they come and go. There are a lot of horror stories on internet and I was scared to death to take this drug but I would take the shot again because it did shrink my 2.5 cm submucous fibroid to 1.8 I'm hoping my body will be back to normal soon but after surgery I'm gonna be on estrogen and progesterone for a month. I hate medicine. F 40 1 months
3.75
9/25/2016
 2  To prevent Breast cancer recurrence Crying spells, fatigue, muscle and joint pain, vaginal itching, decreased interest in sex, mood swings (depression, irritability, anxiety), hot flashes. The side effects of this medication can be extremely difficult, and the mood swings and crying spells can be a complete nightmare. The excellent news is that I have not had a recurrence. I have needed to strengthen my support system, so that I am attending various support groups so that I can weather the mood swings (depression, irritability, anxiety, crying spells). F 51 1 years
22.5
10/30/2015
 1  fibroids heavy bleeding Took one dose on 1/21/15 and have had progresive joint muscle and bone pain to the point can hardly walk anymore ..my feet burn joints constantly ache even when lying down my scrum painful when i get up from a sitting position horrible drug..night sweats...i cant hardly walk this is upsetting the stay away from lupron F 41 1 times
5/27/2015
Email
 5  fibroids None so far. I did have minor muscle ache in my upper left arm but it was nothing serious. No hot flashes, mood swings and etc. I am taking the add back though. Took it the first day I got the shot. So I hope that's what's controlling menopausal symptoms because I feel great. Due to my large fibroids I am taking lupron + add back to hopefully help shrink my fibroids. I couldn't wait to get my first shot due to my heavy bleeding. I take the 1x a month. Dr wants me on for 6 mos max. May be less if fibroids shrink enough for myomectomy. Period did come first month, and 2nd shot did come next day but was only spotting. Just got the 2nd shot around 2wks ago. Dr said its normal due to body has to get used to it. I am very happy so far. Don't feed into all the negative feedback. We are all different and I wish you the best. F 40 2 months
3.75
5/3/2015
 1  endometriosis Lupron ruined my life!! At first I was all for feeling better but I'm regretting ever letting that needle touch my skin. I started lupron after the birth of my second child. I had tried 17 different birth controls that could possibly help or hinder the pain from the endometriosis the one that did help got recalled. I figured wth might as well give it a try. Worst mistake ever! The doctor did not give me a pamphlet just told me of the hot flashes. The first week the hot flashes came and went all day every day. I then started feeling dizzy and faint. My energy was gone. By week 6 I started having signs of a uti so got azo and prescribed meds little did I know it wasn't a uti it was a side effect. My kidneys began to hurt. It hurt to breath it felt as though I had an elephant sitting on my lungs.Then my whole body started to weaken to the point I couldn't open a jar that had previously been opened. My muscles and bones ached it hurt with every little movement. My body then began to swell(this side effect is still with me it's been several months since I've had my last dse) my ankles swell the second I put them on the floor each mornings the rest of the body parts soon follow. I had lost all interest in sexual activity.I soon got depressed I felt worthless couldn't even play with my kids. My marriage got rocky bc of how I felt. I started getting bumps under my skin on my neck, shoulder and back and it was very painful. My primary care physician said shingles but i don't think F 26 3 months
1 shot
7/14/2014
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 3  Shrink fibroids before surgery Severe muscle and joint ache. Loss of concentration, moodiness,jittery,and mild depression, headache. Feels like a severe case of the flu. Period never stopped but did slow down. Was scheduled for 3 shots but I can only take 2. Too painful. It hurts to open my car door. I hope this wears off soon.Although it feels like the fibroids are smaller. F 45 2 months
1X M
2/11/2013
 1  Fibroids Muscles and joints ache nonstop all the time.. hot flashes. Hurts to get out of bed, from seated position.. not as flexible as I used to be.. hurts to walk.. I'm in constant pain F 37 3 times
8/1/2012
 1  deep tissue endometriosis Tremendous weight gain, hot flashes, bone burning, joint and muscle pain, loss of eye lashes, some hair fell out, couldn't stay asleep, memory loss, thyroid issues, throat issues. I did 9 shots of lupron every four weeks. I am now about 2 years from my last shot and still have horrible side effects. Bone and joint pain is still horrible, I still can't sleep, and my eye lashes still won't grow back. Despite several RX weight loss pills, I have not lost any weight. Once active, I now just lay around all day because my entire body just hurts too much. F 23 9 months
1X M
7/5/2012
Email
 1  Pre-surgery for Lap and hyst High blood pressure, increased heart rate, deppression, anxiety, major leg pain, insomnia, muscle spasms, shivers and sweats, forgetfulness, irritabilty, cry for no reason, back pain, skin on face is dry and scaling, extreme fatigue and feeling of hopelessness, lack of appetite , nausea, vomitting, diarhea I started a week ago with add back estrogen, now just crying a few times a day. I wish I would have never taken this drug and really hope these side affects wear off. Went into the hospital for a racing heart in the middle of the night, they are referring me to a cardiologist. I did stop bleeding and have less cramps. Feel free to eamil me if you are going through something similar. F 43 3 weeks
3.75 1X M
12/15/2011
Email
 1  Endo This drug is Poison period. 15 years after stopping the medication, my bones are breaking, I have fibromyliaga and had to have a hysterectomy anyway. I have severe bone and muscle pain, horrible IBS endo pain along with many other issues that come from using lupron. Research this drug before you think about taking it. F 36 12 months
11.25 1X M
8/31/2011
Email
 3  fibroids, anemia bone and muscle pain, hot flashes, tiredness, vaginal bleeding, abdominal pain my doctor put me on this to stop my periods so i could build up my blood count so that i could have surgery. i am and always has been anemic. since i do not accept blood he did not want to do surgery to remove my 4 large fibroids while i had a low blood count. i have super heavy periods and i hope that removing my fibroids will help me to have "normal" periods. anyway, this medication is making me bleed! i started bleeding 6 days ago and i continue to bleed. nevertheless i had a doctor appointment yesterday and he said my blood count is better and i can have the surgery next week. i don't know how my blood count can be better since i have been losing blood. but great let's do this and be done with it. when will the bleeding stop? i was most worried about weight gain but so far i actually think i am losing weight. i am doing zumba and being very strict on my diet so that i won't gain and besides that my abdomen hurts so i don't feel much like eating some days. first week my back and hips hurt off and on but that has gone away mostly. my hip hurts sometimes but that may be from zumba classes. little bit of hot flashes, but not too bothersome. mostly i am irritated about the bleeding. it is steady and has not stopped for 6 days now. F 38 3 weeks
3.75 1X M
3/12/2011
Email
 1  Severe endo. Severe and continual headaches/migraines, never ending muscle pain, hot flashes, chills, nausea, flu like symptoms, severe joint pain (finger, hands, wrists, knees, ankles, toes, jaw, neck, back, hips, etc), significantly increased jaw pain (had previously had several failed TMJ surgeries in 2008 and 2009, and had been feeling relief with physical therapy and pain management...until starting this injection. MUCH WORSE NOW!!!), drastic weight gain (40-50 pounds), mood swings, very emotional, trouble sleeping, tired all the time, severe cramping (like endo returning), although no bleeding since starting shot 4 months ago. My GYN insisted that take Lupron after my recent surgery. I want to have another baby, so to "buy me time" before he does a hysterectomy (this is my 5th endo surgery) I said OK. The side effects have been terrible. The doc denies any side effects could be caused by Lupron, and claims to have never heard of such symptoms. My other specialists say the damage is irreversible, and that I may not recover from the damage to my joints/bones. I have degenerative disc disease, severe arthritis, TMJ disorder (worse from multiple failed surgeries), etc. I was planning to get pregnant asap, but there is NO WAY that I would even want to try for baby when I feel so terrible now. Prior to starting Lupron, my TMJ and arthritis were manageable, and I was feeling great. I haven't been able to work since starting Lupron. I feel as though I have never healed and still have terrible endo pain/cramping. No bleeding though. That is the ONLY positive thing about this. I will update when/IF my symptoms improve. Wish these docs would stop pushing this drug and actually listen when you complain of side effects. The doc says “I’ve never heard of that. That is not related to Lupron” and rush me out the door. You can find ample info online about the negative side effects of Lupron from thousands of people that have been on it, yet they continue to claim there are no side effects. WHATEVER! F 27 4 months
x1 1X M
12/29/2010
Email
 1  menorrhaghia x11 months I have been having SEVERE pain in my lower leg, behind the knee, behind the thigh, and in the hip. I've done nothing to irritate any muscles, tendons, ligaments. This pain is almost unbearable. No relief no matter what I do. Doctors just blow it off like it's muscle pain, but I had absolutely NO PROBLEMS except excessive bleeding prior to this shot. I have been to the doctors office three times in 22 days, and still have not gotten any resolution. They know that this is part of the side effects of this medicine. I got the Lupron shot along with a Depot Provera shot, which I was told would offset any side effects from the Lupron; IT DIDN'T. I'm still bleeding like a pig!! Only now, I am in agony because my left leg and hip cannot be relieved even with strong pain meds, muscle relaxants, heat compresses, cold packs, and pillows. I have been having this pain for 18 days with no let up. DO NOT GET THESE SHOTS!!! DO NOT GET THESE SHOTS!! DON'T DO IT!!! F 52
1 shot 1X O
11/23/2010
 1  endometriosis headaches, moodiness, agitation, hot flashes,chills, nausea, bloating, muscle aches, severe fatigue, forgetfulness, suppressed appetite, decreased sex drive, back pain, dizziness, severe pain (the same pain for the last 9 yrs), hair loss, high cholestrol I started having the pain in Dec 2001. I got diagnosed with endo in Aug 2005 got put on lupron depot the first time had really bad mood swings, depression and hot flashes the got pregnant with my son. In 2008 after I had my daughter I had a hysterectomy (they removed my uterus and cervix). I continued to have the same pain so when I moved I had my new doctor check. They did laproscopic in Jun 2010 and they confirmed that I still had endo. Went on the Lupron depot in Jul 2010 (3 mth shot). I can't take the progestrine (my body went numb when I was on it and i passed out-the doctor said that i was allergic to it b/c of the estrogen-my body produces to much as it is) Went to the doc yesterday and he thought it was weird that I was still in all this pain. So I get to do an ultrasound, cat scan and possibly another laproscopic surgery. The pain hasn't stopped it has gotten worse and with all the side effects I will not take it again. F 28 4 months
11.25 1X O
10/6/2010
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LUPRON DEPOT  (LEUPROLIDE ACETATE):  Leuprolide is used to treat advanced prostate cancer in men. It is not a cure. Most types of prostate cancer need the male hormone testosterone to grow and spread. Leuprolide works by reducing the amount of testosterone that the body makes. This helps slow or stop the growth of cancer cells and helps relieve symptoms such as painful/difficult urination. Talk to your doctor about the risks and benefits of treatment.   FDA Approval Date: 1989-01-26 (Sources: U.S. Centers for Medicare Services, FDA)

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