ZOLADEX Reviews (GOSERELIN ACETATE)

Average Rating: 2.9 (291 Ratings)

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 ANTERIOR PITUITARY HYPOTHALMIC FUNCTION

 Type: Rx Drug

  

ZOLADEX  (GOSERELIN ACETATE):  Goserelin is used in men to treat prostate cancer. It is used in women to treat certain breast cancers or a certain uterus disorder (endometriosis). It is also used in women to thin the lining of the uterus (endometrium) in preparation for a procedure to treat abnormal uterine bleeding. Talk to your doctor about the risks and benefits of treatment. Goserelin is similar to a natural hormone made by the body (luteinizing hormone releasing hormone-LHRH). It works by decreasing testosterone hormones in men and estrogen hormones in women. This effect helps to slow or stop the growth of certain cancer cells and uterine tissue that need these hormones to grow and spread.   FDA Approval Date: 1989-12-29 (Sources: U.S. Centers for Medicare Services, FDA)

  

Results are sorted by Date added.

Key to Ratings: 1=LOW (I would not recommend taking this medicine.)
5=HIGH (this medicine cured me or helped me a great deal.)

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RATING  REASONSIDE EFFECTS FOR ZOLADEXCOMMENTSSEXAGEDURATION/
DOSAGE
DATE ADDED
 
 4  Endometriosis hair loss, a heavy hair loss!!! acne, mood swings, hot flushes, bone pain, osteoporosis. F 25 6 months
10/31/2012
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 1  Breast cancer when young.. Hot flushes pain in stomach from implant..constant sick feeling itching..pins n needles..being sick..and it didnt stop periods like it was meant.. F 43 2 years
25
10/19/2012
 3  Uterine Fibroids Hot flushes but diminishing, restless legs, dizzy spells, pins and needles and numbness in hands (not known if this is result of injections), generally tired Have now had five injections - one more to go. Have large fibroids (eight month pregnant uterus). Even though side effects have been difficult it has been better than constant flooding (ended up in hospital twice) and pain as I had not reached menopause (at 57). Hoping menopause will kick in after finishing treatment otherwise it will mean a sub-total hysterectomy. Fibroids appear to be shrinking a little but not a great deal and bleeding stopped. F 57 5 months
3.6 mg 1X day
10/16/2012
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Patient History
 5  Prostate cancer No libido,hazy thinking,lack of concentration,hot flushes,mood swings. The last two injections have been really painful.I seem to have become sensitive to the rather large needle.Bruising at the site (tummy) and quite sore for a few days.No problems previously.Same doctor same everything else.Will have a local in future. M 64 2 years
3.6 1X M
10/9/2012
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 3  awaiting hysterectomy Just had my 2nd injection yesterday, feel awful, disturbed sleep, night sweats, cannot concentrates, very emotional. Roll on the next one !!!!! F 38 1 days
9/24/2012
 3  Endometriosis Hot flushes, night sweats, increased pulse rate, lower back pain, lethargy, insomnia. Although I've been bleeding for 2 weeks (not heavily), I haven't had the usual agony associated with Endo, so am willing to cope with the side effects if it works!! F 34 5 weeks
1X O
9/4/2012
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 2  Endometriosis post-op cystectomy Migraines daily, insomnia, loss of apitite, vomiting, crying,angry,depression, sweating, bad hot flushes all in month 1 i'm dreading the next 5 :( I'm receiving this zoladex treatment after I had a 9cm chocolate cyst removed from my left ovary through laparotomy I'm hoping this suppresses the disease I never want to experience that pain again! F 21 6 months
3.6mg 1X M
7/24/2012
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 3  Prostate Cancer stage 3 Was diagnosed with Prostate Cancer stage 3, and prescribed with hormone treatment to be followed by Radiation therapy, either Brachy or beam therapy. Reading other peoples side effects just wanted to say I am feeling lucky So far side effects are general tiredness, and not sure if my aching joints are Zoladex related as I also have polymyalgi Rheumatica and RA being treated with methotrexate. Before starting Zoladex treatment my wife checked potential side effects and changed my diet as follows; Now eat only Soya bread (in UK we get Burgen's Soya & Linseed Loaf), to date no hot flushes, and minimal mood swings, my wife swears by Soya for all menapausal symptoms, she used Alpro Soya milk in cereal occasionally. worth trying if it eases discomfort of hot flushes. M 72 3 weeks
10.8 1X O
7/23/2012
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 2  Endometriosis Hot flushes, insomnia, mood swings, highly emotional, loss of libido, nausea, headaches, flu like symptoms. F 20 4 months
7/22/2012
 1  Prostate cancer Jaw twitch, headache, waves of nausea whole day, irregular heartbeat, difficulty breathing, can't sleep, general weakness, loss of memory, muddled thinking anxious, super sensitive skin, hurts to touch things, quality-of-life here is near zero, taking this will make you wish that you were better off dead, advice, don't take this stuff Take this drug off the market M 71 3 days
Injection 1X AN
7/16/2012
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 4  Endo/Adenomyosis Extreme endo pain, bleeding and moods in first month. Then felt really well, no pain, no bleeding. Now at 5th injection have hot flushes, night sweats, painful bones in feet, extreme tiredness and nausea/flu like symptoms. Am starting counselling too as had to come off HRT due to it feeding endo, and feel very down, crying, etc. I will be on this until a hopeful total hysterectomy with oavary removal. F 37 5 months
3.6mg 1X M
6/24/2012
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 3  endometriosis Hot flushes, migraines, nausea, mood swings, sore joints. F 28 6 months
3?
5/12/2012
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 3  endometriosis Nausea,moody,dizziness,terrible headache,flushes,sweating a lot F 28 9 months
80mg
5/10/2012
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 3  Endometriosis Migrains , sick feeling in my stomach causing loss of appetite, disgusting skin very dry and acne, joint pain, spotting, cramps ! Very moody, cry over the stupidest things that usually I wouldn't even blink at, depressed feeling started kicking in after the 3rd dose. I've already had operations to remove it but that was less then a year ago and it's already worse then the start. I guess it's helping with no periods but definently thrown in the deep end hoping for the best results possible so this was worth it F 21 4 months
5/7/2012
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 3  severe endometriosis, pre surgery On the 4th day after implant each month suddenly felt dreadful with chills, severe nausea and loss of appetite lasting 48hrs with some abdominal and back pain. First week severe headaches, following weeks mild occasional headaches. Hot flushes. Waking up throughout night feeling hot. Dry lips, skin and hair. UTI. Joint aches, mostly in shoulders. Apathy and depression. Zero libido. Painless but heavy bleeding for 1 week after zoladex was implanted. On positive note no period, no endo pain. Will find out how successful zoladex treatment was when I have laparoscopy after three months of supression. Doubt I would agree to use this medication again due to side effects. F 31 2 months
1X M
5/2/2012
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 4  PROSTATE CANCER The Zoladex as a medication works fine; I've had it over 17 years whenever my PSA exceeds 4 along with Casodex (Prevents flare) 6 times; 5 times I sat in a chair and the RN grabed abdominal flesh and shot the slow 12 week release Zoladex under my skin. THIS LAST TIME THE RN ORDERED ME TO LIE FLAT ON MY BACK IN A BED TELLING ME IT WOULD BE EASIER FOR HER TO ADMINISTER AND SHE SHOT IT INTO MY ABDOMINAL CAVITY AND LACERATED A MAJOR ARTERY CAUSING MASSIVE HEMORRHAGING WHICH I ESTIMATE ABOUT 4 PINTS OF BLOOD INTO MY ABDOMINAL CAVITY; THEY DIDN'T SIPHON AND TOLD ME IT WAS BEST TO BE NATURALLY ABSORBED AND THIS IS CAUSING ME LONG LASTING PROBLEMS. HOSPITAL IS IN DENIAL FIRST TELLING ME IS WAS A MEDICATION REACTION AND THEN TELLING ME IT WAS THE FAULT OF THE SYRINGE. ASTRA ZENECA SAID THEY WOULD INVESTIGATE AND NOTIFY THE FDA AND DIDN'T SO I FILED REPORT WITH FDA AND WILL HAVE LEGAL ACTION AGAINST ALL PARTIES. I noted in FDA files someone in 1999 had colon and intestines lacerated when Zoladex was injected. Has anyone else had laceration when Zoladex administered, if so do contact me! M 79
1X day
4/20/2012
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 4  Endometriosis & Adenomyosis F 30
3.6mg 1X M
4/6/2012
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Patient History
 4  Endometriosis Terrible headache after first injection, lasted 2 weeks. Then slight headache in the 24hrs after each injection. Dry mouth, dry skin, complete lack of libido, painful intercourse, lost weight (am slight anyway so this wasn't good), hot flushes after month 2, terrible mood swings after 3rd month - completely emotional and unreasonable. Month 5 now developing bone pain and exhaustion. No periods, no bleeding, no bloating, no endo pain. Felt generally very well until month 3 when side effects kicked in.However my endo pain is non-existent and I am grateful for that. One more injection to go... F 40 5 months
3.6mg impl 1X M
3/2/2012
 1  Gyne proba Hot flushes, extreme confusion, tearfully, depressed, mood swings, abdo pains, foggy head and could barely string a sentence together. F 35 2 months
3.6 mg
2/29/2012
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 4  Breast cancer, oestrogen positive Hot flushes , low sex libido , joint pain , mood swings ! I get this injection every 28 days and take femara (used to be tamoxifen first 4 years) every day . It is hard sometimes but the alternative is harder . I want to live ! F 44 10 years
3.6mg 1X M
2/17/2012
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