ZOLADEX Reviews (GOSERELIN ACETATE)

Average Rating: 2.9 (291 Ratings)

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 ANTERIOR PITUITARY HYPOTHALMIC FUNCTION

 Type: Rx Drug

  

ZOLADEX  (GOSERELIN ACETATE):  Goserelin is used in men to treat prostate cancer. It is used in women to treat certain breast cancers or a certain uterus disorder (endometriosis). It is also used in women to thin the lining of the uterus (endometrium) in preparation for a procedure to treat abnormal uterine bleeding. Talk to your doctor about the risks and benefits of treatment. Goserelin is similar to a natural hormone made by the body (luteinizing hormone releasing hormone-LHRH). It works by decreasing testosterone hormones in men and estrogen hormones in women. This effect helps to slow or stop the growth of certain cancer cells and uterine tissue that need these hormones to grow and spread.   FDA Approval Date: 1989-12-29 (Sources: U.S. Centers for Medicare Services, FDA)

  

Results are sorted by Date added.

Key to Ratings: 1=LOW (I would not recommend taking this medicine.)
5=HIGH (this medicine cured me or helped me a great deal.)

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RATING  REASONSIDE EFFECTS FOR ZOLADEXCOMMENTSSEXAGEDURATION/
DOSAGE
DATE ADDED
 
 4  Fibroid removal hot flushes, mood swings, insomnia,dizziness, no sex drive, tired, bloated, emotional - crying at the drop of a hat. had a 9 x 9 cm fibroids outside of uterus. First attempt to remove it was unsuccessful due to too much bleeding during operation, however they removed my appendix as it was infected and stapled up the fibroid as they cut into it. They said I would have lost my right side of reproductive organs and needed a full blood transfusion if they were to remove it on that attempt. Recovery time was 6 weeks before I could do anything again, during that time I had 3x zoladex injections each month to shrink the fibroid. the dr then successfully removed the fibroid and the injections had worked to shrink it down. I just wish I had the injections before my first operation so I didn't have to go through 2 operations. Recovery time was better, still sore can't lift anything heavy for 4-6 weeks, waiting for period to return after injections still, headaches and tired all the time. F 26 3 months
30mg 1X M
6/16/2013
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 5  To shrink Fibroid for operation Hot flushes, headaches, loss of balance, irritable, weight gain, acne I had a fibroid the size of a 7 month term pregnancy (rare for my age) in order to shrink it down for surgery i had to use the zoladex implant.my specialist prescribed the higher dose and just to have it once. it shrunk my fibroid and after just a month it was small enough that i could have the surgery!! after the surgaty i still had the zoladex in my system for about 8 months. my symptoms were pretty minor i had menopause symptoms (hot flushes, mood swings, i was irritable) but nothing too bad or that wasn't worth dealing with. i just wanted to put a more positive story on here as this drug helped me immensely and was worth every hot flush as now i will be able to conceive naturally. F 23 9 months
10.8mg 1X O
6/11/2013
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 5  Endometriosis Occasional hot flushes and insomnia and more recently slight joint pain F 39 9 months
1.6 implan
6/10/2013
 2  Severe endometriosis Had 3rd laparoscopy in Dec 2012 after collapsing with endo pain (I sneezed and ripped a lump of it embedded in a muscle near my left hip). I had 5 sections of endo removed including on bladder which caused bladder damaged which has thankfully repaired. I started on the zoladex implant 8 weeks after surgery which I believe was far too long after and should have been given earlier. For the 1st 2 months the pain was reduced dramatically and I felt little need for any painkillers (co-codamol) but in this last 4-5 was the pain in my left is unbearable, causing tears & major discomfort. I'm thinking of stopping the zoladex as the endo causing the pain is outside of my uterus/womb and I'm thinking is not fed by hormones therefore no making any difference. On top of the pain, the hot flushes & night sweats are awful and I'm constantly tired. I'm just hoping that the medical profession can find some better way of controlling this disease without the need for more surgery which I'm sure I'm going to have to have F 36 4 months
30mg
5/26/2013
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 5  endometriosis To begin with (first 30-40 days) absolute awful headaches and nausea to the point I couldn't do daily task and had to spend 1-2 days in bed around 1wk after the first two implants. 50+ hot flushes per day some days althoiugh annoying were bearable. But huge reduction in pain, I'm so thankful for that, my need for pain killers reduced by around 80%. Just about to have the 4th of 6 agreed implants and I'm finding affect on pain is reducing abit and need more pain killers again but nowhere near as many as before zoladex. Was on tramadol/morphine before zoladex now just the odd cocodomol for the pain. Find I'm in pain towards afternoon/evening -especially after a long day at work/looking after my daughter. However side effects have eased quite a bit less than 20 hot flushes per day but I am getting hot all the time and cold sweats in the night. Main issue is inability to sleep,waking throughout the night and being unable to get back to sleep despite being very tired. Also finding I'm getting a bit muddled when talking trying to recall the right words or names I'm looking to say. I have actually lost weight on zoladex, only 4-5lbs i find not got much of an appetite and have not yet returned to regular exercise. Also found after I drank alcohol for the first time on this it seemed to completely 'switch off' the effect of the zoladex and the horrendous endo pain was back for around 3days and the side effects disappeared completely so I won't be having alcohol til its well clear of m F 30 6 months
3.6mg
5/21/2013
 1  IVF I have had severe headache on both sides of my head.I regret taking this injection! F 40 1 months
3.6mg
4/29/2013
 4  Treatment of Fibroids pre Surgery I have been on Zoladex injections for 3 months for the treatment of Fibroids pre surgery. I was supposed to have one more but i have been told by the Doctor that it isnt required as the Operation date is now set! After reading some peoples experiences i just wanted to add my own as i found other peoples reviews helpful. My side-effects arent that bad so far, most of them are a mild inconvenience. I found that the weight gain can be controlled if you exercise regulary and dont over induge, especially if you are feeling low or emotional. Exercise aslo made me feel alot better and helped me when i couldnt sleep. Im a person that loves my glass of wine and my daily coffee, so i didnt cut out alcohol nor coffee, but my side effects arent that bad still indulging on these guilty pleasures. Im not sure if the medicine has worked yet as im due for surgery in 3 weeks time. I do feel that the pressure on my bladder from the fibroid has reduced as i dont feel the need to go to the loo that often now. And no more heavy, painfull cramping periods, so in that respect it is working!. Hope this helps anyone who has fibroids or is taking the Zoladex 28 day injections!, will update the post once ive had surgery! F 32 90 days
3.6mg 1X M
4/16/2013
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Patient History
 3  Endometriosis Headache, nausea, vomiting, feeling unwell, dizziness, upset stomach Had Laparoscopy in Nov 2012 and some endo removed, mirena fitted, but had bad side effects from mirena. Gyno suggested zoladex as still in pain. 1st injection increased pain for about 2 weeks, some side effects but not to bad, week 3-4 pain most days but nothing i couldn't cope with. had 2nd injection 1 week ago OMG. side effects within 2 hours of injection, severe pain, the next day more pain, vomiting, bad head to the point where i had to go to bed, spent the next two days mostly in bed ( not great when you have kids) still got bad head, dizziness, cheeks tingling and warm, nausea and my stomach is also upset.NO WEIGHT GAIN, as i eat very healthy and exercise loads when I'm up to it. When I train I am pain free, due to your body releasing endorphins, that combined with meditation keep my mind and body strong. F 35 6 months
3.6mg 1X M
3/19/2013
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 1  Menorrhagia/pre-uterine ablation Emotional liability, severe bleeding, memory issues, fatigue, hot flushes This drug did not work, in fact, it had the opposite of the intended effect. My blood loss has gotten so bad that I've gotten badly anemic and my period just no longer stops. I have to be in progesterone 3 times a day just to slow it down. F 43 1 times
10 1X O
3/17/2013
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 3  currently taking for endemetriosis I have had it fitted 4 1 week currently experiencing suicidal thoughts depression hot flushes nausea tiredness and dizzyness doc says it shouldn't work just yet but it obviously is and I am worried that it says only 2 take for 6months max yet I'm on it for 9months!? F 20 9 months
30mg
2/14/2013
 5  Endo Initial mood swings, emotional , hot flushes, night sweats, some nauseous headaches F 47 6 months
3.6
2/7/2013
 3  Fibroids to reduce size Hot flashes about every 30-40 minutes mostly in evening . Night sweats. Inability to sleep due to being boiled or freezing. Severe blinding headache on waking . Dry skin . Very tired. Foggy brain. Feeling fed up. F 47 3 months
1/16/2013
 4  Prostate Cancer Worst side effect is erectile dysfunction, shrunken testicles and penis. Next comes fatigue and general tiredness. Next is loss of memory and lack of mental energy. Restless sleep and hot flashes, muscle weakness, paticularly in legs, 16 pounds weight gain. Inceased appetite for food. These are the main effects. Otherwise I am happy and glad to be alive. 10.8mg every 3 months. M 64 2 days
10.8mg 1X O
1/15/2013
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 4  Intravascular leiomyomatosis Taken with Letrozole massive tumour shrinkage (myomas/fibroid in vascular system). Chronic insomnia, problems with immediate short-term memory, zero libido, severe hot flushes, joint pain & stiffness, muscle spasm in hands/fingers, lethargy & low mood. DHEA, calcium / magnesium, vit D, fish oil DHA helped. Avoid wheat and beer, alcohol generally will make symptoms worse. Now stopped taking and trying ulipristal acetate (specific to fibroids only) plus calcium-d-glucarate, DIM, matcha green tea & phytoestrogens: red clover, black cohosh ie SERMS & SPRMs, to flush out excess estrogen & progesterone. Be careful before stopping Zoladex. It works. Get your disease stabilised before trying alternatives and always involve your clinicians, even if they don't agree with your choices they can offer blood tests & imaging to check disease remission or progression as you try something else. Btw, one month off Zoladex side effects remain even though it can take as little as 14 days to flush from system, my guess is that it can take much longer! F 40 2 years
3.6mg
1/4/2013
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 2  Endromerriosis Really bad mood swings, irritable & depressed. F 29 6 months
12/28/2012
 1  Severe Endometriosis Suicidal thoughts and depression. Constant hot flashes and huge weight loss. F 23 6 months
N/a
11/26/2012
 2  nauses headaches daily I have had the injection once and will not be getting it again it has made my pain 10 times worse F 22 1 months
1
11/23/2012
 4  Endometriosis Hot flushes, night sweats, tiredness, bowel issues, mood swings. As someone who rarely sweats, the night sweats and hot flushes were the hardest part of this treatment. The last 6 months being endo pain free has been amazing to have a "normal" life - whether this treatment has helped long term, only time will tell! F 26 6 months
1X M
11/6/2012
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 4  endometriosus/cysts on ovaries After 17 years of endo pain.10 surgeries a radical hysterectomy leaving the ovaries behind.I had surgery last november and two weeks after I had a cyst that bleeds into itself every cycle.I was having pain ALL the time and it was interfering with work my social life.Upon last admission with regular morphine every hour over two days Zoladex was suggested to which I had on discharge.I have now been on Zoladex for three months and due to start my first quarterly injection.I have to date had NO pain.However my side affects are brutal.Depression nausia sleeplessness hot flashes and terrible debilatating bone aches especially between my hips and knees.It's so severe at times I have to take DHC to combat it.I will admit that this is NOTHING compared to the pain I dealt with daily and the severe cycle pain with the cysts so I can say that although the side affects are strong it's liveable. F 33 3 months
3.6 mgs 1X M
11/6/2012
 3  endometriosis (after Laparoscopy) Tiredness, hot flushes, disrupted sleep, slight moodswings F 29 6 months
11/2/2012

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