ZOLADEX Reviews (GOSERELIN ACETATE)

Average Rating: 2.9 (291 Ratings)

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 ANTERIOR PITUITARY HYPOTHALMIC FUNCTION

 Type: Rx Drug

  

ZOLADEX  (GOSERELIN ACETATE):  Goserelin is used in men to treat prostate cancer. It is used in women to treat certain breast cancers or a certain uterus disorder (endometriosis). It is also used in women to thin the lining of the uterus (endometrium) in preparation for a procedure to treat abnormal uterine bleeding. Talk to your doctor about the risks and benefits of treatment. Goserelin is similar to a natural hormone made by the body (luteinizing hormone releasing hormone-LHRH). It works by decreasing testosterone hormones in men and estrogen hormones in women. This effect helps to slow or stop the growth of certain cancer cells and uterine tissue that need these hormones to grow and spread.   FDA Approval Date: 1989-12-29 (Sources: U.S. Centers for Medicare Services, FDA)

  

Results are sorted by Date added.

Key to Ratings: 1=LOW (I would not recommend taking this medicine.)
5=HIGH (this medicine cured me or helped me a great deal.)

Page: 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15


RATING  REASONSIDE EFFECTS FOR ZOLADEXCOMMENTSSEXAGEDURATION/
DOSAGE
DATE ADDED
 
 5  Prostate Cancer M 60
30 MG 1X day
7/20/2015
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Patient History
 4  fibroid shrinkage prior to surgery Hot flushes (felt like the top of my head would blow out), long lasting bruises, insomnia, high blood pressure, memory loss, joint pain and stiffness especially in hands. My doc gave me the injection in December 2014 after my period to shrink large fibroids to facilitate surgery. She informed me that I would have menopause-like symptoms including stopped period. I was given 1 dose and we waited until the fibroids had shrunk enough. Surgery was performed 1st June 2015 and went very well. I'n in my 5th week of recovery and now waiting to see when my period will return since i would like to have a baby. Overall the hot flushes was the worst part of the zoladex experience. Considering how much better i felt after taking it (no period meant no cramps and pains), I think it was worth the inconvenience. F 35 6 months
10.8 1X
6/28/2015
 1  breastfeeding cancer Severe mood swings. Severe joint psin. I could barely bend my knees .fatigues and muscle pain. It was debilitating. Mood swings and depression bordered on suicide. Also my TSH went from 0.78 to 5.5 in one month. The only thing different in my life was zoladex. My oncologist won't answer questions about if zoladex effects your thyroid. F 42 1 months
3.6
6/17/2015
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 1  Pelvic pain Terrible hot flushes all day and night. Anxiety, sleep disturbance, dizziness. Had two of my three doses, refused third and waiting for side effects to diminish. Dreadful F 44 3 months
4/23/2015
 2  Endometriosis Severe weight loss 30lbs in 3 months back pain fatigue severe mood swings irritability bruising F 31 4 months
4/1/2015
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 4  Endometriosis Hot all of time but loads of hot flushes an night sweats, migraines as well as really bad headaches, dizziness, nausea, emotional and mood swings, loss of sex drive, insomnia and raised blood pressure. the implant has worked as far as endo pain has gone and heavy bleeding and periods have stopped. Hot flushes and most side effects happened with 1st implant but felt relatively well until the 4th implant when migraines and nausea started and all side effects intensified. I've been having days in bed because of migraines making it hard to function. F 42 5 months
3.6mg 1X M
3/28/2015
 5  endometriosis I hate this so much, im still currently having the injections. But I want to stop them. I'm so over emotional,angry and snappy. My sex drive has gone non existant. My boyfriend thinks I hate him because of all this. Dizzyness, headaches really intense pain like someones trying to pop my head. Joint pain mainly my ankles and knees. I have this really odd patch of skin (red purply) on my arm that just won't budge. But the worst part for me is how its messed with my emotions,im not me anymore and that's making me feel worse. Endo didn't make me that depressed I felt suicidal - zoladex has! :'( F 29 6 months
1/10/2015
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 1  Uterine Fibroids Terrible hot flushes and night sweats. Migraines, emotional and moody. Severe joint pain. Bad acne on face, back and shoulders (still not gone after 4 months off treatment). Hairloss, my hair literally started coming out in clumps. Short term memory loss (still not any better). Trouble sleeping. It did not work for me and had to take HRT to control the mood swings and emotional mess I became, counteracting the hot flushes. F 34 3 months
1X M
1/8/2015
 4  Endometriosis Hot flushes,night sweats,lose of interest in sex and dry vagina. Despite the side affects I have been on zoladex for 1 year now.I have had 6 monthly cycles twice before.For me ,I haven't had periods or pain for about 7 months now.I used to be in agony on my hands and knees in pain,doped up to the eyeballs with Tramadol and would bleed for weeks at a time,very heavily.The side effects do die down over time and at least they don't cause pain!!!The best thing to do if you have to take Zoladex is invest in lots of lube and try out sex toys,especially if you can't take HRT like I can't.Zoladex is better than the Mirena coil or having to go drastic and having a Hysterectomy in my opinion. F 37 1 years
3 monthly
11/20/2014
 3  fibroids I have awful night sweats and joint pain and backache all the time F 42 4 months
36mg
10/15/2014
 1   I am 60 and thought I was through the menopause.My husband is taking zoladex but my hot flushes seem to have increased since he has had the injections.am I picking up his pheronomes F
1X day
8/29/2014
 5  endometriosis, cysts, fibroids One of these other reviews prompted me to write this as she is also a 51yr old female, it sounded exactly like me. After the 3rd week of my 1st injection, I staggered into A and E and asked them to help me I felt so ill. I had the most blinding headaches that caused me to cry just to relieve the pain, my blood pressure shot up, I felt constantly nauseas, felt as though I couldn't get my balance and was going to collapse, I felt detached from the world and not myself at all, really really ill. I have refused further injections, it is just over a month and waiting for this awful medication to get out of my system. If the pain of endometriosis comes back I will have a laparoscopy instead to buy me time to go naturally through menopause which will automatically clear it. I am never messing with synthetic hormones again as I do not fair well at all. F 51 1 months
3.6
8/16/2014
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 1  reduce size of fibroids spaced out, nauseous, lost nearly a stone in weight, no appetite, severe depression,mood swings, panic attack, raised heart rate and blood pressure, slurring words,headaches, hot flushed, night sweats, very heavy period For me this has been a nightmare from hell. I got symptoms from the second day when things I looked at appeared green and I felt very spaced out. After 2 weeks I had a really heavy period and was sent to A and E. Then I was violently sick. I had constant nausea and no appetite. I found it very hard to eat anything and lost over half a stone in weight. Then panic attacks started and I would cry for hours for no reason.I had episodes where I would start shaking and slurring my words and the GP saw that my blood pressure and heart rate would shoot up during thisI nearly hit the nurse at the second implant so wasn't given it!!! Now am hoping this horrible drug for me gets out of my system quickly. Still crying!!! F 51 1 months
3mg 1X M
8/12/2014
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 4  Prostate Cancer T3b Hot flushes up to 10 per 24 hrs. 3stone weight gain (Can't shift it) tired, legs ache, finger nails soft and flaky. Penis and testicles have shrunk, no erections and loss of sex appetite. Some mental confusion and regular forgetfulness, quite happy to just drift through the day. We moan about this drug, but it helps us to live a better life, (possibly) at the end of the treatment. Quite often, you want to quit using the drug, but you persevere for the light at the end of the tunnel, when you are cured, (well for this innings of the terrible cancer). M 59 3 years
10.8mg 1X O
6/2/2014
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 3  for breast hormonal cancer want to Sweating at night & day feeling depressed low very tired.Given me early menapause F 44 7 months
inj1.8
5/19/2014
 1  Decrease recurrence of breast cance Horrible night sweats, soaking wet 4-5 times a night, and horrendous hot flashes leaving me dripping in sweat Look at anything else other than this drug, I am even considering ovary removal, MO suggested Effexor on top of Zoladex, I am aleady on Tamoxifen so that would be three meds, have to start the shots them again at the end of May and am dreading it. They make life miserable. Also made me very depressed. F 46 3 months
39 1X M
5/13/2014
 1  endo Tiredness headaches severe swelling in abdomen F 30 1 months
5/12/2014
 5  Endometriosis Hot flushes, tiredness, acne, bloating, a little short tempered F 20 6 months
4/1/2014
 5  prostate cancer Extreme fatigue,hot flushes,aching legs. M 70 1 years
not sure
3/18/2014
 5  Prostate Cancer, systemic met.s Irregular sleep patterns, increased appetite (as in hungry ALL the time), associated weight gain, diurnal water retention/nocturnal release ( 1/2 gallon not uncommon), phantom stabbing pains anytime, rare balance problems, occasional aphasia (very frustrating), hair growing in strangest patterns on head, and straightened as well, total lack of interest in sex, am cold much of the time, tastes changed ( do not really care for meat any longer), and have difficulty rising from sitting on floor. Here is the thing: there is no free ride, and we are all affected the same to some extent, and differently to other extents. Zoladex affects the pituitary gland and it is beyond the scope of this narrative to explain the downstream effects of that... read up on your pituitary gland. I was told early on that exercise and a strict low cal diet, multivitamins and supplements recommended by a physician would greatly improve not only the response of the cancer, but the impact of the side effects. That has been singularly my salvation, having dealt with Leuprolide for 2 years before this Zoladex. I really thought the Leupron was killing me faster than the cancer, and I refuse to go back on bucalutamide. The cancer is a cakewalk compared to the side effects of the Casodex. My point is, this is a trade-off. These drugs buy you a little time, 5 maybe 6 years, but at a cost to your quality of those years. Our pharmacological choices are narrow for now, but get up and out, get away from the table, and change your attitude. You can do those things and suffer tolerably well, or you can sit at the window and complain about the side effects and how you think it may not be worth the trouble. Either way, you won't be doing it for long, so make the best of a bad situation. M 62 1 years
1X AN
12/13/2013
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