ZOLADEX Reviews (GOSERELIN ACETATE)

Average Rating: 2.9 (291 Ratings)

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 ANTERIOR PITUITARY HYPOTHALMIC FUNCTION

 Type: Rx Drug

  

ZOLADEX  (GOSERELIN ACETATE):  Goserelin is used in men to treat prostate cancer. It is used in women to treat certain breast cancers or a certain uterus disorder (endometriosis). It is also used in women to thin the lining of the uterus (endometrium) in preparation for a procedure to treat abnormal uterine bleeding. Talk to your doctor about the risks and benefits of treatment. Goserelin is similar to a natural hormone made by the body (luteinizing hormone releasing hormone-LHRH). It works by decreasing testosterone hormones in men and estrogen hormones in women. This effect helps to slow or stop the growth of certain cancer cells and uterine tissue that need these hormones to grow and spread.   FDA Approval Date: 1989-12-29 (Sources: U.S. Centers for Medicare Services, FDA)

  

Results are sorted by Date added.

Key to Ratings: 1=LOW (I would not recommend taking this medicine.)
5=HIGH (this medicine cured me or helped me a great deal.)

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RATING  REASONSIDE EFFECTS FOR ZOLADEXCOMMENTSSEXAGEDURATION/
DOSAGE
DATE ADDED
 
 3  breast cancer Nauseas, headache, no appettite, hotflahses, tiredness the first days after implant placement. Side effects are milder after 4-5 days till next implant. F 45 8 months
3.5 mg 1X M
7/26/2017
 1  Breast cancer Had one injection ER over 3 months in 2013. Red rash at inj. site in 24 hours followed by nausea, migraines, fatigue, excessive fluid retention/ weight gain. Caused lymphedema in BLE & abdomen & still have this S/E in 2017. Unable to loose any weight...& now on disability 4 years later!! Stop making Zoladex! This drug should be illegal! F 50 3 months
ER
7/11/2017
 5  stage 4 prostate cancer metastatic hot flashes, feeling of weekness, very tired, off balance, stomach got very large, personality changes, very overly emotional , depression After the first injection my PSA dropped from 48 to 0.1 I took Casodex for awhile, became ineffective. Started Xtandi 9/2016. I receive my shot every 3 months. My wife discovered a prescription cream that numbs your skin, place a glob of it on spot and cover it with Press & Seal. At least an hour, no more than 2. Some nurses prefer you sitting up, some prefer u laying down. I dont feel a thing. Recently my nurse at Johns Hopkins laid a ice pack on the area for 5 minutes. This worked! I dont use the Elma cream any longer to numb my skin. M 79 3 years
30mg 3X M
6/5/2017
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 3  prostate cancer pre treatment Dizziness and balance problem on walking, Hot flushes, progressive lower back pain from sitting position, Fatigue, Blistering rash and loss of appetite. I received a smart injection in the stomach muscle which I have been told to be at three month interval before radiation therapy . M 67 2 years
1X O
5/29/2017
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 3  Endometriosis - temporary measure. Bowl bleeding when I have to relive myself. Only had one injection of 10.8 mg. I'm into my second week now. Is this normal? F 38 2 weeks
10.8mg
5/4/2017
 5  Fibroids Early menopause for 5 mths. No other side effect except a lot of bruising Don't look when you have the injection . Shrunk my fibroids . Vertually no period pain when periods returned for about 3 years! It works for me thank you F 47 3 months
X3 months
4/21/2017
 1  Fibroid reduction Fibroids ballooned in size almost instantly (opposite of desired effect). Serious depression - very bad in my case as I have suffered from cyclothymia. Injection was so bad I screamed and site still painful after 1wk No information given me by hospital/ consultant prior to taking drug even though requested, and I had no idea injection would be a capsule. A sadistic treatment prescribed by a sadistic consultant. Another consultant has prescribed me Esmya, to be started next month. I urge for the boycotting of Zoladex, as it is clearly POISON! F 43 1 months
3.6mg 1X day
4/14/2017
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 1  to hopefully cure endo Hot flushes very bad, headaches, loss of bone density, loss of hair(which i had to cut off) .. insommia, low libido,moodiness, tummy cramps, brittel nails and skin rashes... Yes it has brought on early menopause but im hoping it helps to clear my endo and if it doesnt then God be with me👌 as i really want another baby 😯 F 35 3 months
6 months u
3/30/2017
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 4  Cronic abdominal pain heavy bleed Extreme tiredness cracking joint in ankles and wrists loss of grip tender stomach loss of periods Brilliant side effects are way better than being in chronic pain now off the Oxycontin although tired I have quality of life as I can go out and not drop to my knees in pain at any moment after 2 months of being on treatment I had a little niggling pain occasionally but nothing in comparison to before taking the drug however I'm only on this for a Max of 6 months F 36 4 months
2/16/2017
 5  Endometriosis and PO No sex drive , breathing difficulty, pains in heart and chest and down left arm, tingling feeling in legs and arms, emotional , angry Anxiety is high , voices in head , depression joint pains and stiff , breasts sore and discharge from them , can't sleep Awaiting hysterectomy finally after 13 years of hospital admissions and 14 operations on the women hood system Couldn't walk let alone stand as I got older it got worse , collapsed all the time from losing the feeling in my legs , started painkiller form the start just to get up ,lost 8 babies, severe pain and bleeding through inter course and after takes days to recover this has helped me a lot and everything must come with a price , get this broken system out of me F 29 3 months
1 month
1/31/2017
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 3  Endometriosis I got on well with Zoladex. Only some hot flushes and tiredness to start but after 3 months changed to Prostap and periods returned with a vengeance along with all the other symptoms the Zoladex had stopped. Back on Zoladex now as GP said that it wasn't right and now just feeling wiped out! Will wait and hope that things settle. Back to consultant in a few weeks. I much preferred the Zoladex to Prostap but feel that perhaps neither are actually all they are cracked up to be! F 47 5 months
1/17/2017
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 3  heavy periods had first injection 10 days ago, positives: reduced flow in period. Negatives: extreme tiredness, aching joints in legs, anxiety, feeling of loneliness, short tempered, nausea and insomnia F 29 6 months
3.6mg 1X M
1/17/2017
 2  Uterine fibroid, Heavy periods no side effects till now heavy bleeding after two weeks of my first implant F 32 1 times
10.8 MG 3X O
1/12/2017
 1  Prostate cancer Severe depression at times. No self confidence, no self esteem, suicidal. Everything around me seems black. No joy anymore. I have been told to take it for the rest of my life. I will have to stop it though, there is no real life with it. Let nature take its course. I'd allow 3 months for the effect to wear off, 3 months of worthwhile life and then 6 months of unpleasantness, then goodbye. M 68 2 years
10.8 1X O
11/26/2016
 1  Pms. Omg. Fatigue nausea fuzzy head couldn't think.didn't want to speak headache oversleeping.back pain violence.suicide thoughts and I can go on. Got in at 5 pm after having my 1st injection went straight to bed on a Friday night have no idea why it is now Monday and I have not left my bed!! Have not hardly spoke to y 16 yr old son havnt washed cooked nothing.I have slept too much. Feel dreadful.I would rathe be dead.!! I don't have no family or friends so no help with my son who is seriously ill and now looking aftr me ! What I will say is it 2orks different for everyone but disgusted I was given this without any questions asked an option of wethr it would suit me and told only side effect is menopause! ! If anyone knocked my door I would probably kill them!! Ruined my life that was already ruined !! And left to fend foryself.will not he having a second injection would rathe commit suicide ! Doctors to eager to give without a proper consultation F 47 1 days
11/14/2016
 1  Endometriosis and associated sympt. Increased anxiety, severe mood swings, chronic sadness, severe joint pains, short term memory loss and other memory problems, chronic fatigue, vaginitis, severe hot flashes and night sweats, absolutely no libido, breast shrinkage, muscle loss, weight gain, increased sweating, severe vaginal dryness so painful that I cannot have penetrative sex (have not had sex in over 1 year), breakthrough bleeding, moderate pain and bruising around injection site, reduction in bone mineral density, UTIs, severe hemorrhoids, painful urination and defecation, severe constipation, etc. Lower back, ovarian, and abdominal pain decreased the first 2 months after my 1st injection. Chronic nausea disappeared, only to return around the 5 month period, although it was not daily as it was before. Various pains returned after about 2 months and steadily increased until it was worse than before starting treatment. After 4-5 months of Zoladex, I had to start on a buprenorphine transdermal patch in order to try and keep the pain under control. Due to my increase in pain and other symptoms, I had another laparoscopy 7 months after starting treatment, to remove endometriosis from bowels, ureters, ovaries, fossa douglasi. Obviously Zoladex did not help with my endometriosis as it was found during my surgery. It is now 8 months after my last injection, and I am still suffering from all side effects reported. My state of life is much worse than it was before starting the treatment and I would not wish this upon anyone else, especially those who also suffer from endometriosis or adenomyosis. F 20 10 months
10.8 mg 1X O
10/3/2016
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 4  Endometriosis I was very concerned regarding the amount of negative experiences other sufferers have had on this drug, however I am pleased to say that it has not been too bad at all..... Hot flushes to start & fitful sleep....... Other than that fine. Side effects are far more bearable than the pain of the endometriosis! Due to have 2nd injection on Thursday so fingers crossed will continue as first month. Feeling hormonal however as injection wears off. Really helped reduce endometriosis pain. No where near as bad side effects as expected. Very pleased! F 47 1 months
3.6
9/26/2016
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 4  Endometriosis Some hot flushes at night, some bone pain, very low mood, vaginal dryness, loss of libido My endometriosis pain was severely prior to taking zoladex. It is almost completely gone and I am 2 months through a 4 month cycle prior to starting ivf. The pain that has subsided is amazing and enables me to live my life however the low mood I am experiencing is devastating. I'm just trying to cope day to day so I don't become too overwhelmed by my depressive feelings and thoughts. It's hard. F 30 4 months
Implant in
7/3/2016
 1   I am 39 i was diagnosed 9 months ago with congestion pelvic syndrome . I was suffering with servere pelvic pain & back pain, leg pain tiredness , Loss of limbo , due to the pain . Since starting this medication I have turned into a different women . My moods are all over . I wake up will constant pain in my buttocks and legs during the night aswell as pain during the day, hot flushes , .I am now very emotional all the time & depressed . I suffer with vaginal dryness . My Sex drive as gone completely . My marriage is suffering with all the side effects. I am now waiting for a scan . This is to see how my vains are doing . Ive told the consultant im not having anymore . This injection as ruined my life for 6 months . I really wish I had done my research before i agreed to having it . At the time i was just thinking please take this pain away . Now its been a waste of time because its not made any difference to the pain . I would not agree to this . Please do your research before agreeing . Some it might work for however it can make things worse . It did with me . F 6 months
6/8/2016
Email
 2  Ovarian cysts and endometriosis Hot flushes, irritability, insomnia, headaches, very emotional, depression, mood swings, short term memory loss, not feeling myself, dizziness. I had to take the injections after laparoscopic surgery for removing ovarian cysts. I had a one week period that started the second day after the first injection and it was heavy bleeding. Now it's been 5 weeks after the last implant and I'm waiting for my period to come. I wouldn't recommend this treatment. F 27 3 months
3,6 mg
5/29/2016

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