PEPCID Reviews (FAMOTIDINE)

Average Rating: 1.5 (431 Ratings)

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 DISORDERS, ACID PEPTIC

 Type: Rx Drug

  

PEPCID  (FAMOTIDINE):  Famotidine is used to treat ulcers of the stomach and intestines and to prevent intestinal ulcers from coming back after they have healed. This medication is also used to treat certain stomach and throat (esophagus) problems (such as erosive esophagitis, gastroesophageal reflux disease-GERD, Zollinger-Ellison syndrome). It works by decreasing the amount of acid your stomach makes. It relieves symptoms such as cough that doesn't go away, stomach pain, heartburn, and difficulty swallowing. Famotidine belongs to a class of drugs known as H2 blockers. This medication is also available without a prescription. It is used to prevent and treat heartburn and other symptoms caused by too much acid in the stomach (acid indigestion). If you are taking this medication for self-treatment, it is important to read the manufacturer's package instructions carefully so you know when to consult your doctor or pharmacist.   FDA Approval Date: 1986-10-15 (Sources: U.S. Centers for Medicare Services, FDA)

  

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Key to Ratings: 1=LOW (I would not recommend taking this medicine.)
5=HIGH (this medicine cured me or helped me a great deal.)

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RATING  REASONSIDE EFFECTS FOR PEPCIDCOMMENTSSEXAGEDURATION/
DOSAGE
DATE ADDED
 
 1  Gerd In addition to the anxiety, palpitations, and agitation I have noticed terrible pain and stiffness in my back and my legs. I can barely walk in the mornings. The stuff is poison and I can't find a Doctor who can find me something else that doesn't have all the side effects. not only that they don't believe that this drug causes the side effects that I have experienced. Works great for gerd but not worth the terrible side effects. F 60 5 days
20 1X day
1/4/2023
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 2  GERD This medication really impacted my mental health. In the month that I took it, I was depressed w/ suicidal ideations. This medication made me feel horrible, the only benefit was that it allowed me to eat a bit. I am dealing with brain fog and dissociation because of this medication. After a month of taking it, I decided to no longer take and I hope that my depression will disappear. F 36 1 months
20MG 1X day
12/27/2022
Email
 1  Gastritis Makes me extremely nauseous. Last night I woke up with terrible back and chest pain. This afternoon I had a small anxiety attack - got cold sweats and sense of doom. Getting off of it. Not worth the side effects. F 61 2 weeks
40 mg 2X day
12/23/2022
 1  Stomach pain and acid in esophagus Burping a lot constipated feels like food not digesting M 61 2 months
20 2X day
12/13/2022
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 1  Heartburn Intense anxiety, panic, racing heartbeat, palpitations, muscle and joint pain, muscle twitch, fatigue, muscle weakness, neuralgia (pins and needles), insomnia. This stuff is poison. I casually bought a bottle OTC to help deal with some minor heartburn, and took it probably 5-10 times over the course of a couple weeks without even thinking about it. Out of the blue I started to develop fatigue, twitching muscles, and muscle and joint pain so bad I was sure I hurt myself. Started to get pins and needles like nerve damage. The knees and feet were the worst except it would also pop up all over the rest of the body too which was bizarre. Then the anxiety and panic attacks kicked in and things really went off the rails. Sudden bouts of fear, waking up repeatedly with racing heart and palpitations. Multiple trips to urgent care, several days without sleeping, benzos from the ER, multiple visits to my GP, MRI by an orthopedist, seen by a neurologist and rheumatologist, all the bloodwork they could come up with and... nothing. They said I was healthy, I thought I must be dying of some mystery disease that nobody could find, or I was losing my mind. Then one day I happened to come across the reviews and there were all the symptoms right in front of me, and it finally hit me that I'd taken the Pepcid shortly before everything went to hell. That was a few weeks ago now. The muscle and joint pain is significantly better, and neuralgia is mostly gone. Anxiety and mood aren't as bad as they were at the beginning, but still not as stable as they should be either, and sleep is still not fully returned. Pepcid isn't just unpleasant, it's dangerous! M 39 6 times
20 1X AN
12/7/2022
Email
 1  For acid reflux Ever since I took Pepcid I got super sick, bloated, anxiety, trouble eating, loss of appetite, back pain, accessible urinating, constipation, insomnia, constipation, discomfort in abdomen, I felt like it was the end of the world, can't eat Right, I got no energy all I wanna do is sleep, I cry feeling like I'm dying, I always feel bloated now from the constipation. IDK WHAT TO DO ANYMORE!!!! I just want to be normal again ! This is day 6 of me having symptoms and I would never take this again, I took this over the counter without my doctor prescribing it to me. F 30 10 days
20 2X day
11/16/2022
 1  acid reflux1 Horrible anxiety heart racing feeling crazy and heart palpation,it worked but would rather drink hot water for the gerd. glad I saw this page, thought something was wrong with my heart.so scary. stop this medication asap F 58 1 days
1X day
11/5/2022
 1  Acid reflux and Gastritis Racing heart rate when standing or walking, weakness, shakiness, anxiety and sadness. I was in the hospital in June, they added Pepcid x2 daily didn't have any tachycardia prior. It's awful. Now I'm told you have to ween off, what a nightmare. Horrible Drug! F 52 4 months
20 MG 2X day
11/4/2022
 1  Gerd I just found this page thank God. I am living in hell for about a month. Started with severe pain in knee. Then both. Pins needles. Difficult to walk. 2 weeks ago severe anxiety. Severe stomach pains. 4 ER visits. Blood tests good. Can't leave house. Slow moving bowels. On and on. I took one at 9 this morning. I'm stopping. Not saying it might be other factors but after reading these comments I have almost every symptom. The fear is killing me. Hopefully this stuff clears out sooner then later and I can deal with the aftermath. 62 0 days
20 2X day
11/3/2022
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 1  Stomach issues Terrible anxiety, pulse rate was out of control! M 70 4 days
20mg 2X day
10/28/2022
 1  Acid reflux Increased pressure on LES , persistent GERD . Recommended by JK M 62 5 days
20mg 5X day
10/24/2022
Email
 1  Acid reflux, histamine intolerance I can't believe how much my experience with this drug matches everyone else's on this page. I started to take this medication 5 days ago due to a bout of acid reflux caused by my severe histamine intolerance issues. From the very beginning I started to experience strange feeling in my chest, a mixture of left sided pain and breathlessness. Suddenly I started to worry about my heart but of course didn't connect any dots. Within the next few days the strange feeling in my chest continued but last night was definitely the worst. I do suffer from an anxiety disorder but didn't experience any panic attacks in a long time. Last night after midnight I was suddenly awoken with the worst panic/ anxiety feeling; my vision became wild, I had hot flashes, sweats and pins and needles in my extremities. Like everyone else here I couldn't understand why this is happening all of the sudden. When I woke up in the morning the horrible anxiety feeling was still there but I right away knew it must have been pepcid; After doing extensive research I found out that pepcid very often affects CNS due to its ability of blocking acetylcholine which is one of the very important neurotransmitters in the brain. Low acetylcholine levels create a host of psychiatric symptoms including severe anxiety and brain fog. It's been over 24h and I still feel very anxious. I really hope that soon I will feel like myself again. Really terrified experience and I would definitely recommend an informed consent before eve F 38 5 days
20 mg 1X day
10/16/2022
 1  Reflux (heartburn) Neck, leg, shoulder and back pain. Heart pounding, sweating. Insomnia and feeling of anxiety and a needles and pins sensation in my arms, feet and legs. Some twitching in my calves. The symptoms started on the 2nd day of starting Pepcid. It took a few days to realize that the only thing it could be was the Pepcid. I stopped the Pepcid and it took about a week for the symptoms to stop. F 67 5 days
20 mgs 1X day
10/5/2022
 1  Gerd, vagus nerve damage Burning shredding pain in fascia of shins, calves, thighs, hips, pelvic floor, abdominal wall, diaphragm. Muscle cramping. Tendon pain in ankles, wrists, elbows. Muscle weakness/fatigue. Eventually leading to deep bone pain. Difficulty with movement. Extreme anxiety and insomnia. And, depression, crying frequently. Rapid transit of food, weight loss. It took over 20 doctors appts, 2 er visits, 2 urgent care visits, 3 MRIs and 2 ultra sounds before "one" doctor said it was the famotidine. I was referred to neuro, ortho, pain mgt, physiatrist, nutritionist. When I discussed with my pcp, she said she was unaware of the side effects but let's hope that's what caused all your pain and you can get better! I am 6 weeks off medication. Fascia, muscle, bone pain all resolving. Anxiety and depression gone. Not I have a hiatal hernia I believed caused by the tearing of the fascia of my diaphragm. I wish I had found this site and other medication reviews sooner. The side effects started 17 days after starting the medication……probably the reason the medication states do not to take for more than 2 weeks. My doctor did not monitor me while in this medication. I hope this review might be helpful to others who might be suffering with similar side effects. F 57 11 months
20 2X day
9/29/2022
 3  Gastritis, GERD Systolic BP increases shortly after taking. Anxiety and or anxious feelings. Muscle aches. Fatigue. Headache. Works ok for a few weeks but effects wear off and dosage must be increased or switch to a PPI for a while before returning to Pepcid. M 55 100 days
20 MG 1X day
9/5/2022
 1  Gastritis and duodenitis I posted on August 13 about my horrible side effects from Famotidine, but want to clarify that I took it for 7 months, not 7 days. I started using it in September 2021 and stopped using it in March 2022. I am still experiencing side effects. Please let me know how much longer until these terrible side effects will subside. Do not use it!!! F 71 7 months
20 mg 1X day
8/31/2022
Email
 1  Gastritis Anxiety, depression, impending doom, fast heart rate, loss of appetite, stomach pains, constipation, overall feel so uncomfortable in my own body. It sucks that it's been helping the acid reflux / gastritis but I'd rather suffer then have to deal another day with those horrible side effects!!! F 31 13 days
40mg 1X day
8/17/2022
 1  Gastritis and duodenitis I started taking Famotidine in September 2021. After a week or so I started feeling very shaky, anxious, had muscle weakness in calves, muscle twitches in calves, trembling, periods of feeling cold, migraines, extremely high pulse rate at rest, arm weakness, insomnia, pain in neck and shoulders. I was also nauseated a great deal of the time. I went to my PCP, endocrinologist, GI doc and now a psychiatrist. After I found this forum, I immediately stopped taking the Famotidine. That was in March 2022. I now have periods (maybe 1-2 weeks) of symptoms subsiding - and then they start again. Does anyone know how long this will continue? I'm desperate to feel normal again. When the symptoms reoccur, I barely get off the couch. Although most of the doctors I've seen won't definitively say the symptoms are due to Famotidine, they don't say it's not the Famotidine. One doc even said symptoms can occur with more frequency in older adults. Please let me know if you've had similar experiences, and if so, how long did the symptoms persist. And do not take this medication. It's debilitating. F 70 7 days
40mg 1X day
8/13/2022
Email
 1  Acid Reflux Irritability, sadness, a sort of numbness in chest that was pretty scary, would not recommend It got rid of my acid reflux but was definitely not worth it since it brought on side effects that were worse F 26 1 days
10mg 1X day
8/12/2022
 1  To transition from Prilosec. I started this medication because I have having breakthrough acid on Prilosec. I was recently diagnosed with an anxiety disorder. I started to notice that I'd wake up with a high heart rate. All doctors said it was anxiety. But then yesterday my heart rate got really high and I felt chest pressure. I spoke to GI doctor and he asked me to use one more time in isolation. I did last night and phew, it happened again. I was able to sleep with something else but after waking up the high heart started again and kept increasing. I ended up taking an Ativan and beta blocker to lower everything. Yikes. I hope it will get out of my system and not return. Be careful. F 48 8 days
20mg 2X day
8/11/2022

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