Reviews for LUPRON

75 ratings: (side effects include muscle)

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 DRUGS USED IN DISORDERS OF GROWTH HORMO HORMONAL BIOLOGICAL RESPONSE MODIFIERS

 Type: Rx Drug

  

LUPRON  (LEUPROLIDE ACETATE):  Leuprolide is used to stop early puberty (precocious puberty) in children. It helps to delay sexual development (such as growth of the breasts/testicles) and the start of menstrual periods. It also helps slow down early bone growth to increase the likelihood of reaching normal adult height. Leuprolide works by decreasing the amount of sex hormones that a child's body makes (estrogen in girls, testosterone in boys).   FDA Approval Date: 1985-04-09 (Sources: U.S. Centers for Medicare Services, FDA)

  

Results are sorted by Date added.

Key to Ratings: 1=LOW (I would not recommend taking this medicine.)
5=HIGH (this medicine cured me or helped me a great deal.)

Page: 1 2 3 4


RATING  REASONSIDE EFFECTS FOR LUPRONCOMMENTSSEXAGEDURATION/
DOSAGE
DATE ADDED
 
 1  ER+ breast cancer Migraines, blurred vision, nerve pain, twitching muscles and aches, severe neck and shoulder pain, dizzy, chest pains, shortness of breath, severe hot flashes, tinnitus and hyperacousis, high cholesterol It's been 5 months since my 1 month month shot and still have all these horrible side effects. F 51 1 months
7.5mg 1X M
12/4/2021
 4  Prostate cancer First 9 months few side effect, then body hair loss, muscle weakness, aches from waist down, loss of libido, brain fog, insomnia, fatigue, but PSA dropped from 41 to 0.30, and that's what it was for. Had 5 doses of 8, Hope the symptoms fade when finished the course. M 64 15 months
22.5 5X O
2/15/2021
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 1  prostate cancer Where do i start,anxiety,depression,huge around middle, tinnitus, muscle and joint aches, high cholesterol, lethargy so tired,nasal congestion, headaches, changes in taste and smell.shrunken nuts, no sex for 4 years, boobs with lumps in. This stuff can change your life, you will want your old self back. Some men it works without side effects great for them,but it is not a one size fits all drug,as many on here know to their cost. I love life but lupron takes all joy out of it.Yes it lowers psa and hopefully keeps you alive,but i did not expect so many side effects and after being off the stuff for more than 2years i do not think things will get better.It does not seem to me that lupron ever leaves your system,it remains in some way. The bottom line is if you have no choice take it,but take as little as you can to remain who you are and stay alive.This is just my opinion on my experience on lupron, get the full facts for yourself on lupron if you find yourself being told you need it, I hope that you do not. M 74 18 months
11.25 1X O
8/29/2020
 1  Prostate cancer ADT along with radiation Absolute hell. Clinical depression, anxiety, fatigue, dizziness close to the point of passing out, massive loss of strength, muscle tone and definition, loss of body hair, total loss of interest in sexual intimacy. Testicular shrinkage, neuropathy in fingertips. This sh*t needs to be banned by the FDA. Quality of life issues far outweigh the medical utility of this drug to the point that I'm sure its maker spends large amounts of money covering up the lives lost due to suicide caused by the depression this garbage causes. As many on here have related, it is truly the devils drug. M 58 12 months
30mg/4 mo
6/2/2020
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 1  prostate cancer Short term memory 'loss', my BONES 'hurt', dizzy, lost 50% of my bicep muscles, vertigo, anger & rage, severe Mood swings, 'hot flashes' like 'neural Tsunami's, my BALLS melted away, grew tits, had 'bad' feelings & ideas', could 'snap' in an instant. Lupron Depot is: 'POISON'. When they call it, "Hormone Injection Therapy", they make it 'sound like', they are:"injecting Hormones'. They are NOT, they are 'injecting Chemicals that 'KILL ALL 'YOUR' HORMONES', and poison your "Hyperthalas & Pituitary & Gonads & Seminal Vessels. Your 'manhood' is GONE FOREVER ! Lupron, 'DESTROYS your "QUALITY of life and GIVES you HORRID 'longer life'. M 69 4 months
7.5 MG 1X M
7/21/2019
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 4  Breast Cancer ER+ Stage1 Menopause symptoms: hot flashes, racing heart, insomnia, anxiety, joint and muscle pain, vaginal dryness, zero sex drive, fatigue. I took Lupron to put me into the menopause in order to take Arimidex pills (a treatment option for postmenopausal women with hormone receptor-positive early breast cancer). F 39 5 years
1X M
9/15/2017
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 1  Endometriosis and Uterine Fibroids massive joint and muscle pain,confusion, memory issues, pain at site of needle,extreme fatigue would never have taken this medication if I had known the risks- Lupton didn't even help with my fibroids or end so it was pointless to have it administered. F 45 1 years
8/12/2017
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 1  Prostate cancer Testicles in pain Muscle loss Depression Brain fog Lowers PSA but no quality of life left Recommend orecitomy instead M 73 12 months
Yes
5/1/2017
 3  Prostate Cancer In the beginning up to 30 hot flashes a day. Extreme fatigue, shrinking penis, zero sex drive, ED, muscle loss, body hair loss, scrambled thoughts and hard to stay focused. I get my injection every 4 months and learned quickly to make sure side of injection is totally relaxed. The lupron has done its job at keeping my PSA but at a major cost to quality of life. M 61 2 years
30 mg 1X O
3/31/2017
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 1  Stage 4 prostate cancer Hot flashes , pelvis testicular pain. Fatigue,depression, no sex drive , E D No sleep. Loss of muscle mass Weight gain Ruined who I was and wonder if I will ever be the same M 73 6 months
3/12/2017
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 1  Prostate Camcer Fatigue, muscle pain in legs, depression, shrinking genitals, - this all happened with the three month shots. Just this past month they started giving me six month shots - REALLY WEIRD IMPACT ON THOUGHT PROCESS. Tonight I was telling my wife about a dream I had. Once I finished the story it suddenly hit me that what I described as a dream really happened. I WONDER IF THIS IS RELATED TO LUPRON AND THOUGHTS? I WANT TO DISCONTINUE THIS MED. M 67 1 years
1X O
2/1/2017
 1  Severe endometriosis After being diagnosed with stage 4 endometriosis in 1994, doc prescribed Lupron, a new medication for women, back then, 22 years ago. It is chemotherapy, not meant for anything other than to weaken the immune system and cause so many other health problems, such as fibromyalgia, reduced libido, joint pain, ademyosis, infertility, and migraines. This drug stays in your system the rest of your life!! Do not let your doc force you to take it no matter what!! It made my endometriosis worse, and after earning 2 college degrees, was only able to use them for a few years until I had to go on permanent disability for the rest of my life because of Lupron. I am currently in bed most of the time on 6 medications for pain and muscle twitching, so I rarely get outside or motivated to do anything. It's really horrible. Don't do it, your doc is only prescribing it because they get a bonus from the pharmaceutical company for each dose they prescribe!! It's the worst drug ever. They might as well call it the shot of death, because that is what you will wish for once you take it. F 48 6 months
6 shots
10/1/2016
 1  Prostate Cancer Loss of muscle, cellulite in thighs, depression, zero sex drive, testicular shrinkage, more depression, anxiety, paranoia, ED, even more depression. Shed a lot of tears and lost a lot of friends. I felt like I was losing myself and becoming someone else (with no way back to me). I wanted to refuse the shot after 4 months but I let them talk me into another 3 months. I refused any more injections after 7 months. I felt like I was already dead so what was I hoping to save? I think it has done permanent damage to my brain. Ask more questions and be skeptical of vague answers regarding this drug. It has no curative quality, just delaying. How much time will it add to my life? Hard to say. How long will impotence last? Hard to say. Forever? Hard to say. How long will I take the drug? Hard to say. Is it damaging my brain? No statistical evidence is available. Will I ever see a brighter day? Hard to say. I wanted answers about me, not statistics. Even on the WWW I can never find anything but vague answers veiled with meaningless statistics about the effectiveness and the side effects from taking this drug. Have doctors become just statisticians now? M 60 7 months
3 mo shot 1X day
4/26/2016
 5  Prostate Hot flashes ,joint and muscle pain,loss sleep,short memory loss, anxiety, Stage 4 cancer controlled by this drug that is why I am satisfied. Not many options for me that might be worse or better. Has kept me from a predictable lifespan sofar M 58 2 years
4 month
11/23/2015
 1  breast CA severe bone & muscle pain:severe memory problems,anxiety& depression.short of breath:decrease vision:mood swings:major weight gain:hot flashes I was already in full blown menopause,did not need it.dr. lied about many things,said main side effect hot flashes:with all the complaints for decades why is it still being given? F 47 5 months
not sure
11/23/2015
Email
 3  Prostate Cancer Severe joint pain,fatigue loss of muscle mass, weight gain, loss of strength. M 63 10 months
30 1X O
10/28/2015
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 4  Prostate Cancer Most common ones especially joint and muscle pain in shoulders. These symptoms are much worse with 6-month injection than with 3-month When muscle pain is real bad I can reduce it by forcing myself to relax the muscles and deep, slow breathing. Aerobic exercise helps. Running, fast cycling, and cardio machines at gym. I often don't feel like exercising but force myself to get going and the energy follows. I always feel better during and after exercise. M 62 300 days
45 1X O
4/29/2015
 1  Endometriosis Bone and Joint pain, Nausea, Dizziness, Blurred vision ,sore Muscles, No sex drive, Headaches, Hot Flashes, Strange numbing feeling in my head that I now have to see a Neurologist for, mood swings ,Heart palpitations , heart racing. F 44 2 months
1X O
4/24/2015
 4  Prostate cancer Stage 4 I was taking Lupron in 6 month shots. I had two 6 month shots, and after 1 year, my Doctors & I decided to switch me to 4 month Lupron shots. Before, I really was feeling so bad that I was making arrangements to have a bilateral Orchectomy because of the side effects. Doctor team met and discussed my case. At this time I have been declared cancer free from a Stage 4. Bone scans, CT Scans, and MRIs are clear. At this time I must say I am feeling much better on the 4 month Lupron shots. I still have slight leg muscle and joint aches, but nothing like before. As of my last blood tests, my testosterone level is down to <10. The standards are to have it 20 or below. So, I feel like the Lupron is working fine at this point. My PSA continues to be at a steady <0.010. Had one testosterone flair, one month before I got the 4 month shot. It had climbed to 47, but then dropped to <10 the week before I got the 4 month shot. Doctors were surprised. My doctors are still M 69 1 years
30mg 1X M
2/18/2015
Email
 1  Prostate Cancer Stage 4 Some hot flashes, Muscle and joint pain and muscle weakness in legs. There are times that I can barely walk. Some back and pelvis discomfort.Weight gain (7-10 pounds), more frequent urination (worse that with the enlarged prostate), numbness in hands and fingers (I'm a pianist, and that doesn't work too well). overall lousy feeling at times, mood swings, crying at the least little thing, pain in testicles. Testicle atrophy. Breast size increase and tenderness. My head hair continues to get thicker. Wife comments on that when she cuts my hair. I had a radical prostectomy Dec 10, 2013. I was a stage 4 with a small spot in one lymph node. No cancer in the surrounding tissue. 6 month Lupron shot in Jan. then 8 weeks of external radiation starting in May. I had been a road cyclist. I continue to do up to 2 hours per day on a stationary bike and tread mill, plus weight training. PSA at 69 pre surgery PSA was at 0.2 after surgery Went on Lupron and PSA is now <0.010, and holding at 0. Post Lupron Testosterone was at 27.78, starting to rise and is at 45.28. That's twice what they want. We are switching to a 4 month shot to try and relieve the side effects. There is concern about the rise in testosterone, however my PSA stays at <0.010. I've been on Calcium and VitD and brought my levels up. If it weren't for the side effects, I would recommend Lupron. However my Quality of Life sucks. My Urologist ask If I would consider an Orchiectomy rather than Lupron. After much study, I decided that that would be the best option for me. Fewer bad side effects, And Peace Of Mind about further return of the cancer, if Lupron stop working. Decided to try a 4 month shot and see how it goes. If I'm still feeling as lousy, I'm going to continue with the Bilateral Orchiectomy. Complete body CT Scan Dec. 2014, and that will tell us if there is any other soft tissue involvement. My latest bone scan, clean, no spread to my bones. So to hold all this in tact, we may continue on with the Orchiectomy. M 69 11 months
45mg 2X O
12/6/2014
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LUPRON  (LEUPROLIDE ACETATE):  Leuprolide is used to stop early puberty (precocious puberty) in children. It helps to delay sexual development (such as growth of the breasts/testicles) and the start of menstrual periods. It also helps slow down early bone growth to increase the likelihood of reaching normal adult height. Leuprolide works by decreasing the amount of sex hormones that a child's body makes (estrogen in girls, testosterone in boys).   FDA Approval Date: 1985-04-09 (Sources: U.S. Centers for Medicare Services, FDA)

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