DEPAKOTE Reviews (DIVALPROEX SODIUM)

Average Rating: 3.0 (584 Ratings)

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 ANTICONVULSANTS

 Type: Rx Drug

  

DEPAKOTE  (DIVALPROEX SODIUM):  This medication is used to treat seizure disorders, certain psychiatric conditions (manic phase of bipolar disorder), and to prevent migraine headaches. It works by restoring the balance of certain natural substances (neurotransmitters) in the brain.   FDA Approval Date: 1983-03-10 (Sources: U.S. Centers for Medicare Services, FDA)

  

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Key to Ratings: 1=LOW (I would not recommend taking this medicine.)
5=HIGH (this medicine cured me or helped me a great deal.)

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More on DEPAKOTE: Reviews Summary  |  Drug Safety Information

RATING  REASONSIDE EFFECTS FOR DEPAKOTECOMMENTSSEXAGEDURATION/
DOSAGE
DATE ADDED
 
 5  sezures bi polar disorder What great with my moods and seizures but does affect your teeth I can't seem to find if it shows up as a false negative in a drug test M 32 1 days
1500
7/9/2016
 1  Bipolar manic depression After taking depakote I noticed Orange patches of discoloration o. My skin it's been a year since I stopped taking it and the patches start moving throughout my upper body what do I do M 18 6 weeks
1000 mg a
7/4/2016
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 2  Temporal lobe epilepsy Major hair loss and anxiety. Fatigue. I'm going off slowly it now since it wasn't working and it's messing with my concentration. Now my menstrual cycle is out of whack. It's throwing off liver tests, causing strange right side pain. I worry about my hair and if I should get it cut short until is grows back thicker. I also learned my quack of a neurologist put me on it without liver tests. F 38 7 months
1250
6/21/2016
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 1  Bipolar Pola At first experienced hallucinations then I had a tremendous amount of hair loss almost went bald and I had pretty thick hair F 62 2 years
500 millig
6/6/2016
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 1  schizophrenia effective disorder Massive weight gain I gained 200 lbs I was 489 lbs do not take this med or zyprexa it's awful I can no longer walk and it's horrible trust me it's not worth the good times you will lose Christmas new years birth days and many friends I still can't walk and I been off the med a whole year now M 27 4 years
80
5/12/2016
 3  depression weight gain. stable mood. that is the good thing the only thing I hate is the weight gain I'm going to have to join a gym soon. F 33 6 months
250 2X day
5/1/2016
 1  Epilepsy (wrong diagnosis) Daily diarrhea, Hair loss, Chest pain in the night, Weight loss, Menstrual cycle ruined, Difficulty to come up with words, Forgeting important things, such as name, passwords, id number, etc. I was prescribed this med by a neurologist after one seizure. She diagnosed it as epilepsy. Took the med, and got those side effects. The most terrible effects are daily diarrhea and abnormal menstrual cycle. After the usual menstruation stopped for 3 days, I started to menstruate again for more than a week. Went to see another neuro, he told me it's not epilepsy after all and I have to stop the med immediately. A month after stopping the meds, I'm still having this terrible mens cycle. Twice menstruation a month, and they lasted 2 weeks. Never had it this long. Going to see doctor if this menstruation doesn't turn normal next month. F 24 1 months
500 MG 1xD
4/17/2016
 3  Bipolar Only side effect for me was extreme drowsiness the following day. I took it in the evening. But couldn't stay awake the next day. M 49 3 days
3/18/2016
 3  biopolar diarrhea, headache, nausea, sleepiness, unusual drowsing, dizziness, loss of strength and energy 25 4 months
1500 2X day
2/24/2016
 4  Epilepsy I started at 250/mg per day and now 30 years later I am up to 1000 mg a day to function. I have three different types of seizures. They started when I was nine. We were told that the mood changes would happen and as my sister and I got older that there is the possibility of break through seizures. I have anxiety attacks now, and during my time of the month I have break through seizures. About 5 years ago it finally caught up with me and the tooth decay has started. I have always taken care of my teeth like I am supposed to. Now they break and decay. Its embarrassing. F 39 30 years
1000 mg 1X day
1/28/2016
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 1  Stress, anxiety, depression I became, angry, snappy, had horrible dreams so tired and worse of all suicidal. Felt like I was going plum crazy. My mother is a nurse and deals with this med often with her patients she immediately said stop it now. I stopped and am on my second day without it. I feel little drunk and light headed. But feeling better than before. Praying that's all the withdrawals I have with being on it only two weeks. My mother questioned this med from the get go from a nurses point of view it was extreme high dosage for someone who was not even suicidal to begin with. I was going thru a divorce and had a lot of stress in my life, new job, new home. I have not been so scared in my entire life. I now am concerned about my doctor and his actions we will b talking. F 48 2 weeks
500 mg
11/29/2015
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 3  Bipolar Shadow creatures at night. Bad headaches, back pain, and Hair loss. I was put on depakote and d-amphetamine mixed salt combo for Bipolar, lack of energy and not wanting to be around people. The very first day I took depakote I experienced a severe headache that sent a shooting pain down my spine if I moved. This lasted a week. It seemed to work well during the day. I was able to be around people without being afraid of getting angry or hiding to avoid being spoken too. Halfway in the second week I began to see quick shadow movements. I continued to take the medicine because it improved me during the day. About 3 months of taking the medicine I became paranoid before going to bed. I would see huge shadow spiders crawling on the floor or walls. When I would get to sleep I was awoken by a big bang sound and saw a bright blinding flash. I also developed a bald spot in my head. I was tooken off the depakote and a month after I developed little spots that traveled from my legs to eventually my whole body. It turned to sores that resembeled psoriasis and I had to shave my head because I had large bleeding patches. After being referred to several doctors and a few biopsys they said that it was the after effects of depakote that can linger on the skin several months after stopping the medicine. Will never recommend this medicine. I also want to note that my sons father was put on this medicine at high doasage along with seroquel and he began thinking that his own mother was pouring bleach onto his drinks and has become very unpredictable with his mood F 26 3 months
250mg
9/25/2015
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 1  Severe depression Hair loss, acne, back pain, suicidal, more depressed than ever in my hole life. teeth problems. etc It was heart breaking for me asking a psychiatrist for help with my sadness, and selling me the idea that depakote will help me, and then see how I was decaying mentally and physically. Mi hair, my skin, my mouth, and the panic attacks were horrible. I almost crash while driving. My doctor refused to take me off this drug, I did it my self. I dont need permission to get my life back! F 37 2 years
750 2X day
9/6/2015
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 1  Bipolar manic It had me in such a "zombie" mode I did not feel bipolar. I had every tooth but wisdom, and took great care of them, never had a problem. Till months into taking this my teeth slowly started to decay and hurt and continued to get worse as I continuously brushed twice a day floss every night and mouth wash twice a day. Yet it continued to get worse and I never could understand the problem until I read that was a side effect to this medication, I stopped taking it the problems slowed down but still am having to catch up on getting it repaired which is EXTREMELY EXPENSIVE. The worst medication, I would rather deal with bipolar in a more natural way, due to all the stress from that medication. There should be a lawsuit for this medication. It may not kill people itself, but it makes life miserable. M 30 2 years
8/17/2015
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 1  My son has epilepsy My son loses motor skills he can't talk it comes out as babble but he knows what he wants to say his hands will curl up and his lip will go up i have gone back and tracked his logs of events and this started after put on this medicine he's also on dilatin for grand mal and that works but nothing for the partial seizures has anyone else had these side effects please email me at [email protected] the doc doesn't know what this is but I want him off Also lost weight appetite and when he does eat he ends up vomiting everything up so now going to check about a possible ulcer M 15 1 years
8/15/2015
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 1  My son has epilepsy My son loses motor skills he can't talk it comes out as babble but he knows what he wants to say his hands will curl up and his lip will go up i have gone back and tracked his logs of events and this started after put on this medicine he's also on dilatin for grand mal and that works but nothing for the partial seizures has anyone else had these side effects please email me at [email protected] the doc doesn't know what this is but I won't him off Also lost weight appetite and when he does eat he ends up vomiting everything up so now going to check about a possible ulcer M 15 1 years
8/15/2015
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 1  Bipolar with episodes I have alot of medical problems going on with me. So on day 2 of taken depakote I didn't know which of my problems to blame. The CDDD for the intense neck and back pain? Another stomach ulcer causing this burning all over my stomach? My Thyroid levels are low again, no energy? Depression hit hard, considering suicide...often, very often. And now no sleep and I was hallucinating in the dark. I finally started looking up all of these things and came to find out that it is the depakote doing this to me. Yeah I read reviews now saying it's just temporary, and it's so much better after a month or 3...but this is not for me! Oh and dry mouth, the 1 thing my doctor did say I would get. It sort of helped with me being angry/upset all the time. Now I just don't care. I lay in bed in pain, hungry but can't eat. Oh and painkillers makes it worst (would have been nice to know since I take percocet 2xs day for my Cddd). My doctor swore by this medicine when he gave it to me. Now I'm waiting for him to get into his office to rip him a new one. He knew that I had my Thyroid removed and have gained 52lbs and keep gaining. I didn't something to make me gain more. And what's with the back pain seriously, what causes that? And why does painkillers make it worse, it puts me in pain and I can't even take an asprin to feel better. But to all of you who did stay on it with all these symptoms, good luck to you. After reading up on this med it's going down the toilet. (Weird how somebody would pay money to get high off of these, you couldn't pay me enough to go another 5 days. I guess it works for some, and I wasn't 1). F 33 5 days
250mg 2xd
7/29/2015
Email
 1  Bipolar Hallucinations hand tremmors slowed motor function dizzy tired sea sick feeling I was better without it M 41 1 months
450
7/29/2015
 5  Bipolar Loss of appetite, mood much more stable ,kept me awake for about a week at nights then went away , causes some confusion,anxiety can be worse at first I take this with fluoxetine F 34 2 years
500 mg
7/21/2015
 5  bipolar Afternoon weakness, tired, no interest, ,anxiety M 54 10 months
1500
6/10/2015
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