DEPAKOTE Reviews (DIVALPROEX SODIUM)

Average Rating: 3.0 (584 Ratings)

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 ANTICONVULSANTS

 Type: Rx Drug

  

DEPAKOTE  (DIVALPROEX SODIUM):  This medication is used to treat seizure disorders, certain psychiatric conditions (manic phase of bipolar disorder), and to prevent migraine headaches. It works by restoring the balance of certain natural substances (neurotransmitters) in the brain.   FDA Approval Date: 1983-03-10 (Sources: U.S. Centers for Medicare Services, FDA)

  

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Key to Ratings: 1=LOW (I would not recommend taking this medicine.)
5=HIGH (this medicine cured me or helped me a great deal.)

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More on DEPAKOTE: Reviews Summary  |  Drug Safety Information

RATING  REASONSIDE EFFECTS FOR DEPAKOTECOMMENTSSEXAGEDURATION/
DOSAGE
DATE ADDED
 
 1  Schizophrenia,anxiety,bad thoughts It made me throw up and gave me diarrhea. It gave me moodswings and thoughts of suicide made my chest tight and I also had a mini stroke from taking it After the moodswings and all went away I started getting burning in my brain after taking it it gets really sore too. I have damaged nerves as well I can't take sleeping pills at all depakote messed up parts of my brain and the sleeping meds won't work. F 23 22 days
400
10/21/2019
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 1  Bipolar mood swings and anxiety Hair loss, slowly over months and ended with hardly any of my hair left. Constant stomach pain. Nausea. Migraines. Lethargy, weakness, bone pain. Jaw clenching and neck pain. Permanent tinnitus and some hearing loss. Severe withdrawal syndrome. Brain damage. Depakote is the devil in disguise. Don't take it. When I started it I felt good, but over months I developed more and more side effects. I tried to come of it many times but couldn't due to horrendous withdrawal symptoms. It took me years of gradually reducing it and I'm off it now for nearly a year. I feel permanently damaged by this toxic drug, however I feel so much better off it. It has done permanent damage to my hearing. It also gave me a diagnosis of arthritis which my doctor says has improved so much that he could undiagnose my arthritis. Depakote destroyed my physical health. F 40 10 years
1000mg
8/21/2019
 1  Schizoaffective disorder Inability to concentrate even for a minute, dizziness, lack of motivation, tiredness throughout the whole day, depression, migraines, stomach aches, hand tremors, weird dreams, mood swings, anger issues, body temperature issues, social withdrawral, comprehension issues. Thank God for talk therapy, this drug kills. Was diagnosed with schizoaffective disorder after a flip out because of weed cookies i think and just a whole lot of stress and smoking weed for the first time. Ever since taking this drug ive lost my promotion at work lost all motivation, lost the ability to handle losts M 25 9 months
500mg
7/10/2019
Email
 1  Bipolar Weight gain Insomnia Skin fell of hands and feet Stomach pains Void of thoughts M 28 0 days
3/13/2018
 1  bipolar 1 hypomania 30 lb weight gain, extreme hand shaking & finger tremors. Caused social anxiety. Two-thirds of thick long hair fell out, & was developing drug-induced parkinsonism. The tardive dyskinesia was far worse than from taking Seroquel. Shrink finally started to reduce dose to 750 mg then 500 mg, after I said the drug isn't even FDA or Health Canada approved for bipolar "maintenance." There are no controlled studies to prove that this drug can actually prevent more manic episodes. It is approved for acute mania & it did get the hypomania under control quickly. Now my shrink wants me to stay on the 500 mg/day, saying that it'll help prevent manic episodes. I was also taking 200 mg/day Seroquel, & my shrink says that most likely caused the 30 lb weight increase, so she is switching it to Latuda. I know it was the Depakote causing the rapid weight gain, because I had been on just Seroquel for years. It also caused weight gain at first, but my weight was steady F 66 11 months
1000 mg 1X day
2/26/2018
 4  Bi-polar After taking this drug for Years my teeth are falling out one every other week; so I am having them all Removed 2-07-18 I Had Taken Litium& It Made Me Very Sick So My Doctor Put Me On Depokote!! It Has Helped Me Tremendouly!! I Thank God For The Drug Except It Rotted All My Teeth & Now I'm Having Too Have Dentures Put In Starting February 7,2018 F 68 100 days
1500 mg
1/30/2018
Email
 1  For bi polar disorder Nausea loss of appetite acid reflux Sleepiness blurred vision loss of balance Runny nose constantly cold F 46 4 days
1000 mils
12/10/2017
 5  bipolar Possible issues with memory. Could be age related. Problem is not severe at this time and primarily involves short term memory and ability to access long term memory. M 64 12 years
250 er 2X day
10/23/2017
 5  bipolar 1 increased appetite; +15 pounds, but think its stable now. losing will be tough. Escaped mania without wrecking life. What more could you ask? M 51 4 months
1000 mg 1X day
5/8/2017
 1  one seizure Brain fog. Lethargic, but feel like I always need to be doing something. Withdrawal from family, friends M 56 24 years
750 1X day
3/18/2017
 1  Schizophrenia It doesn't cure any symptoms.depression persists.sleeping disorder persists.i take it regularly night along dinner.doctor says it is preventive.dont accept this drug for any kind of depression as my liver became fatty induced by this drug.i became inactive and sedative.i feel lethargic throughout.i could not have regular sleeping hours. I am relieved of depression symptoms by a genuine homeopath but I could not get rid of side effects of allopathic medicine.can any one come to my rescue M 52 2 years
500
1/20/2017
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 2  Bipolar Zombie. Emitionless...cannot even grieve the loss of my son! Weight gain. F 52 4 years
1500mg
1/16/2017
 1  Sectioned. 1000 depokote 400 depot Asleep day and night. Bald patches, sad, scared, no feelings, Zombie. Better of dead, reduce , impossible. Give it to you so they have peace, torture, cruel, your better of muddling throu life. Poison, don't agree to take it, was given when I was section with depot clopxide let me out on a very large dose , and no one cares. I have no friends I just exsist, moved to a new area, so scared. M 42 4 months
500x500
12/28/2016
 1  Sectioned. 1000 depokote 400 depot Asleep day and night. Bald patches, sad, scared, no feelings, Zombie. Better of dead, reduce , impossible. Give it to you so they have peace, torture, cruel, your better of muddling throu life. Poison, don't agree to take it, was given when I was section with depot clopxide let me out on a very large dose , and no one cares. I have no friends I just exsist, moved to a new area, so scared. M 42 4 months
500x500
12/28/2016
 1  Bipolar Hair loss , weight gain, depressed mood , wierd dreams, hungry all the time , miserable feeling towards well being F 21 3 months
1000
12/20/2016
Email
 1  Bipolar disorder The psychiatrist added depacote to other drugs while I was hospitalized as I was getting overloaded with meds it made me comatose w the combination. The dr. I had didn't know what to do was then sent to a state hospital that detoxes me of everything. Glad I'm alive and refer to depakote as something I'm allergic to so no dr in future puts me on it Scares me F 49 1 days
?
12/16/2016
 2  Epilepsy As a study patient of Depakote I was told I was on the highest dose at that time, 28 years ago. It made getting my undergrad very difficult. Trembling hands, hair loss, weight gain, and cognition issues were just some problems for something that was so so, ay best. Everyone is different so it might help others. M 50 2 years
3500 1X day
12/10/2016
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 1  Stabilize my mood Really bad diarrhea. So weak i can barely stand. Tremors severally in my arms. It spaces me out but I get insomnia from it. Feel a little paranoid also M 49 7 days
500mgs
10/14/2016
Email
 1  MiagrIns Very bad mood changes exhausted loss of equilibrium can't stand feel as though I'm going to fall do not like this feeling at all I am scared to death to take anymore I feel as if I'm so depressed that everything is closing in on me F 50 7 days
500
9/10/2016
 1  Bipolar disorder Took this crap which was prescribed to me,and it did nothing but give me strange dreams and my stomach bloated out. I'm a very healthy 6'0" 215lb.man a I figured I would give this mild dose a try and it did nothing. So I went off it cold turkey and it's been a week and I am just starting to feel better. If you don't suffer from seizure disorder then don't take this crap.Who wants to gain weight and lose their hair? At my age that's a lot of the reasons we get angry that this happens and this Depakote will speed that up even more. M 53 2 weeks
125mg. Bid
9/8/2016
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