Average Rating: 3.3 (737 Ratings)

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 Type: Brand name discontinued; available as generic

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Key to Ratings: 1=LOW (I would not recommend taking this medicine.)
5=HIGH (this medicine cured me or helped me a great deal.)

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More on ACCUTANE: Reviews Summary  |  Drug Safety Information

 1  Acne on face and back. Erectile dysfunction and no orgasm. I can ejaculate, but I feel literally 0 orgasm. Loss of libido. Avoid. Try exhausting other methods to clear acne. M 22 1 years
 4  To clear my skin Dry lips.. joint pain.. light sensitivity.. blurry vision.. hair loss.. rashes.. fragile skin.. sensitive eyes.. nose bleeds every day for 6 months.. lack of sleep.. aggression.. depression.. lack of concentration.. dizziness.. fatigue.. lower back pain.. anxiety .. stress inducing dreams.. loss of appetite.. dry eyes.. cracked mouth.. body aches Besides all the symptoms the drug did what I wanted it to.. just take precautions M 17 6 months
20mg 2X D
 3  Severe Acne I believe it helped my acne out a lot. My dermatologist paired it with an anti inflammatory and a steroid (cephalexin and prednisone.) I'm a lifter and have severe inside elbow pain, low back pain, shoulder issues, and chapped lips. apart from that no other side effects. M 17 8 months
40 1X D
 4  Acne Dry lips Dry eyes Blood noses but taking it at 42 I realised you can prevent blood noses by nasal spray products Didn't sleep well not sure if that's me or the drug I took this drug at 15 years old 20 mg I already was depressed from just having bad acne. I took it again at 16yrs this time 40 mg. Then it came back after a year stronger than ever. I then went back on it 40mg but I was young and just took it when I felt like taking it. I then went back on it at 21 years of age but had bad depression and anxiety so I stopped. I used creams after that. Tried to go back on it at 25 yrs age felt very depressed I had to stop due to my teeth hurting me at the time. So many year on I still struggled with my acne. I had kids at 32 yrs and another at 35yrs my skin was manage with creams. I began to Get large pimples on my chin which left big scars so I have just recently gone back on. I have finished my course and didn't feel depressed or anxious. My skin has improved but I am going back for a stronger dose. It's been a long journey for me. I still would take it nothing else really help but this. For me I am not sure if accutane causes depression or acne causes it. I don't have any other health problems all these years later. F 42 6 months
20mg to 40 4X M
 1  Polycystic Acne I took Accutane many years ago...13 years ago to be exact and I still suffer from cracking joints, chapped lips, dry scalp, dry skin... the list goes on. The cracking joints are embarrassing as I'm only 34 years old. I've waited years for it to stop and it has not. I'm glad I found this thread. I'm going to try taking vitamin D and see if it helps.... I'm seeing a Dr now to try to get to the bottom of it. On top of all of this....I Still Have Acne F 21 6 months
Don't reme 1X D
 1  moderate acne After a couple of weeks I felt that something had changed in my head. I went from being confident and happy to feeling extremely anxious and tearful. 2 months after stopping this drug I became psychotic and felt suicidal. I also then realized that I could no longer get an erection. Nobody knew how to help me, my psychiatrist told me that I was just depressed, I knew it was the drug. Six years on and I still suffer with debilitating depression. Nobody warned me of the hideous side effects. This is a chemotherapy drug and is an overdose of vitamin A. It causes permanent brain changes and is causing misery to thousands of young people. It should be banned totally and the victims compensated for having their lives ruined by incompetent dermatologists. M 26 28 days
20 2X D
 4  Persistent acne I had a lot of side effects with this drug such as hand joint pain, constipation, anal fissures, tail bone pain, dry skin, hair loss, dry eyes, decreased night vision, chapped lips, vaginal problems, persistent thirst, and I am always out of breath when exercising. It definitely helped clear my acne, but I think I was on it longer than needed. After two months my face was completely clear but I stayed on it for three months after that. I am definitely glad I took it, because I was very self conscious about my acne. But I don't think I would choose to take the drug again just because of how many side effects I have had. F 20 100 days
30 mg 2X D
 1  mild acne Erectile dysfunction, low libido, depression, anxiety, PTSD suicidal ideation. suicide attempt. permanent joint pain. Loss of muscle man and no longer able to make gains. ruined skin can no longet tan, loss of hair. aged considerably. Isotretinoin destroyed by life and these side effect are not rare. Research before you take it. Go on forums and believe what victims are saying M 31 8 months
60mg 2X D
 1  minor skin problems every body that takes roaccutane are going to end up with permanent damage arthritis all the joints,you will not be able to move 10 to 20 years after you have taken the drug roaccutane is a chemo drug that has destroyed my body and life.everybody who has taken this drug needs to see a lawyer, roaccutane is a chemo drug that destoys lives,everybody needs to see a lawyer for permanent damage M 49 10 months
40 1X D
 4  Nodules, pus-filled acne HALF MY THICK HAIR FELL OUT it was totally abnormal and I've never had this much hair fall. It also became thin and lackluster. I couldn't even tie it. Hyperpigmentation got worse as I lost so many skin cells on my face and arms. Skin feels tight. Red patches on face that come and go. Dry eyes and sight was unclear at night-you shouldn't drive. Frequent headaches. Really depressed and it makes everyday life and normal activities very difficult. It works but the side effects are definitely not worth it. It's surely not an easy medication to take. My acne scars are still there and my face is kinda red (I have dark skin). I'm currently using bioderma sebium hydra post-accutane. Only use it if nothing else works (I was on treatment for 6 months before e.g. doxy, adapalene, antibiotics etc) and be sure to moisturize frequently (try something non comedogenic) F 17 3 months
20MG 2X D
 1  Chronic Cystic Acne Loss of almost all scalp hair, still losing it, loss of eyebrows, lashes and body hair, change of colour, texture, thickness, elasticity of hair before it fell out. Conjunctivitis, permanent eye pain, problems with night vision, dry eyes, back pain, scalp pain, earache, joint pain, cracked bleeding lips, strange ridges in finger and toe nails. TOXIC POISON. My dermatologist repeatedly recommended this to me, as a safe natural vitamin A product which would cure me in a short time, unlike long-term hormones, and the worst I could expect was to feel uncomfortably dry. I asked him 2-3X about any effect on my (beautiful, thick, curly red hair) and he assured me the effect was just temporary dryness and that as soon as I stopped taking Accutane all side effects would cease. Every time I expressed concern he would say to me : "Who's The Doctor??" I agreed to try it. After three months I stopped and that's when the hair loss started. I had never had a problem before and was not on other meds. What all the experts I subsequently consulted called Telogen Effluvium became chronic and never stopped. The doctors all denied it was related to Accutane! They're still prescribing it. Hoffman LaRoche isn't suffering, my dermatologist (now comfortably retired I expect) never suffered, Health Canada who approved it never suffered. They're all responsible for destroying my life and clearly others' but didn't pay even as much of a penalty as someone who steals a loaf of bread to keep from starving. Dr. L. S. in Montreal, I pray every day that YOU in particular rot in hell. If your doctor suggests you take this garbage, ask him/her first if they are willing to pay for your wigs. I'm thinking, no. F 59 90 days
40 mg 1X D
 1  Acne I was prescribed Clavaris 40 mg at age 57. On day 17 my hearing or ears were ringing so bad I had to stop. My ears still ring all the time after 2 years. I went to a hearing specialist ENT and there is no recourse or going back to undue damage done from this drug. You have to sign a waiver form to get this drug. It is a way to limit or deny lawsuits when you medically fall apart or are damaged by this drug. Tell the doctor NO WAY! Acne will not kill you but this drug will! You are not fighting cancer where you need to take this big a risk. Beware of this drug stay away! This drug has helped some but I feel from my experience to pull it off the market! Ban it! M 57 17 days
40 1X D
 1  Acne Pain in all joints, tendons in the feet, all up my spine/neck. I cant walk right anymore and im only 18. This drug is terrible even though its cleared my face before this i could do whatever I wanted to but now I cant because of the pain in my joints and all. M 18 7 months
80 2X D
 1  Severe cystic acne I developed severe cystic acne in my 20s and by the time I was in my early 30s I tried every antibiotic and medication there was. I was put on Accutane for the shortest course of 15 weeks. I developed severe headaches, totally debilitating. I also had the dry skin and eyes. It wasn't until several years later that I started developing the side effects. I lost my eyebrows, hair on my head thinned, my menstrual cycle ceased permanently so I was never able to have children, elevated liver enzymes, degenerative disc disease which has now developed secondary scoliosis that has progressed to the point that I cannot walk or even stand unaided. I developed major depressive disorder with suicidal ideation, generalized anxiety disorder with panic attacks. These conditions have lasted until now and I am 54 years old today. No Accutane cleared my acne for good it also ruined my life. I eventually lost my business and had to go on disability because of the severe back pain from the DDD and emotional problems. Please take this medication with serious forethought. F 54 15 weeks
30 mg 1X D
 5  for my acne - tired -brain fog -stomach bloat -easily aggitated -nauseous/motion sickness -out of breath -back and joint pain (hips and elbows) - swollen glands -worsened eye sight -skin easily cuts -dry lips and skin month 1 - 20mg month 2 -40mg month 3 -40 mg month 4 -60mg month 5 -60mg month 6 - 70mg month 7 - 70 mg month 8 -70 mg F 22 8 months
70 1X D
 1  Mild acne Terrible hair shedding. Persisted even after accutane. I currently lose 300+ hairs a day and it is thinning by the month. M 18 4 months
40 mg 1X D
 5  Cystic Ance Dry lips, fatigue, splits on the side of the mouth, nosebleeds, back pain (especially laying flat down). I do not regret going on this pill at all. Helped clear up all my ance and painful cyst that I had. Also made my hair less oily so I wouldn't need to wash my hair everyday. F 17 4 months
40 mg
 1  enlarge pore blackheads depression suicide attempts ,dry damage skin that does not heal,arthritis in many joints,knees back spine elbows,life and body destroyed by this drug. do not take roaccutane it is actual a chemo drug that nobody is told about,I was perfectly healthy before i took the drug which has destroyed my mind and body,roaccutane will eventually be banned,but not before it has destroyed everybody who takes it lives,roche i hope you rot in hell you will be held responsible M 49 10 months
20 2X D
 5  Severe Acne Dryness of Vagina, Lips dry, heel pains and knees Low libido, mood swings,dry eyes and watery nose It work wonders . Clears the skin properly F 32 0 days
 4  Acne Extremely dry skin and chapped lips, HORRIBLE dry eyes And tailbone pain whenever I sat down or put pressure on it. It worked well, my skin is nice and smooth with only the occasional pimple. 14 5 months
30 mg

ACCUTANE  (ISOTRETINOIN):  This medication is used to treat severe cystic acne (also known as nodular acne) that has not responded to other treatment (e.g., benzoyl peroxide or clindamycin applied to the skin or tetracycline or minocycline taken by mouth). It belongs to a class of drugs known as retinoids. It works by decreasing facial oil (sebum) production. High amounts of sebum can lead to severe acne. If left untreated, severe acne may cause permanent scarring.   (Sources: U.S. Centers for Medicare Services, FDA)