WELLBUTRIN Reviews (BUPROPION HYDROCHLORIDE)

Average Rating: 3.2 (1230 Ratings)

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Key to Ratings: 1=LOW (I would not recommend taking this medicine.)
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More on WELLBUTRIN: Reviews Summary  |  Drug Safety Information

RATING  REASONSIDE EFFECTS FOR WELLBUTRINCOMMENTSSEXAGEDURATION/
DOSAGE
DATE ADDED
 
 2  Depression Initial symptoms that subsided: jittery "speediness", lack of appetite, insomnia, headaches. Second stage of initial symptoms: extreme anxiety and paranoia that was almost debilitating. Both of these phases occurred when I initially started at 150mg/day and then when I increased to 300mg/day. "Permanent" side effects: (complete!) lack of sex drive, dry mouth, trouble sleeping, night sweats, what I call "brain slides" where there seems to be a momentary shift or turning off inside my head (had a car accident during one of these), inability to concentrate, extreme ennui/boredom, markedly decreased interest in social life, detachment, memory lapses, restlessness. But, hey! No more suicidal thoughts! Went on because of an episodal depression--I'm not normally depressed. The episode is almost resolved, but my doctor is keeping me on it because I haven't been at my increased dosage for six months. I'm tired of this and am going to talk to her very seriously next month about helping me get off of this. I feel like my personality has been sucked out of my right ear and it's NOT because of depression. It is so difficult to get adjusted to for the first month that I'm afraid to go off cold-turkey--I think I could end up hurting myself or someone else. So I need her help in tapering off in the best way possible. This drug is bizarre and there are a LOT of side effects that aren't mentioned in the materials but I see consistently in places like this. I know it's not a controlled study, but this drug is not everything that we're told. F 48 14 months
300 1X day
4/26/2010
 5  depression no happier, better sex drive, lower weight. need i say more F 32 60 months
50 1X day
4/19/2010
 4  depression increased motivation, decreased appetite, more energy, more assertive Around 6:00 p.m. I start to feel irritable and impatient. It's hard for me to relax at night. I am hoping this is a side effect that will go away because I haven't felt this motivated in a long time. F 39 7 days
150 X2 1X day
4/13/2010
Email
 4  Depression Bumpy rash on my hand (started as a small bump, which I picked, thinking was dry skin. soon many bumps appeared. after the rash itched, I scratched it, inevitably causing redness & inflammation. bumps are still on my hand now, & sometimes still itch, usually at night). Headaches. Lightheadedness. Slight hallucinations, Got my period two weeks early. Weight loss. Loss of appetite. While on a road trip, I COULDN'T top thinking how easily I could accidentally lose control of the wheel, causing an accident (this wasn't a suicidal thought, more of me telling to keep alert to prevent it from happening). Despite the list of side effects, I continue to take the drug because I think it is helping me. I am wary of telling my psychiatrist about the rash on my hand because I fear she will take me off of the drug. I do not want to be put on another antidepressant because I do not want to be taking a drug that may impair my sexual function/desire. Furthermore, I hope/think that after time, I will become immune to whatever is causing the rash on my hand, and following that, the rash will disappear. All in all, I am a fan of the drug. I feel that I am generally happier, more hopeful for the future, more confident in myself, and more productive of a person. I no longer feel like I am alone in the world, or that there is very little I can do to get myself out of this depressive slump. After taking the drug for under a week, I woke up one day and realized that there was so much more I could do in my life than sit in bed every day, skipping classing, and watching seasons and seasons of tv shows on my computer. It is like a light bulb went off in my head and made me realize, "Hey, you can climb out of this hole. There's no need to be hopeless anymore." I still have anxiety regarding my future after college, my job, and my grades. But I know this anxiety is stemming from the fact that I am now behind in school because of my depression. I am aware that this something I have to work on myself, and not something a drug can help or cure. F 22 20 days
300MG 1X day
4/13/2010
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Patient History
 3  Severe Depression, irritability Positives: Rapid weight loss, Better outlook on life and looking forward to the future, Manageable anger fits, Increased sex drive, Better, more restful sleep. Negatives: Extreme loss of appetite, paranoia, moody, sleeping A LOT, memory loss, blank spaces in my day. I get sick whenever I think of eating, going as far as thinking that I hate food in general, when I do eat, I'll get half way through my meal and then have to stop because I get nauseous, even the smell of anything food related makes me sick, EXTREME paranoia, to the point where I was pacing back and forth being worried that I was going to die, harder to wake up in the morning, always aroused for no reason, I have periods of time in a day that I cannot remember, increase muscle pain in my legs, including tingling. In general, I'm better off than I was. I'm stable, but when the side effects kick in, they kick in really hard. I am on the generic version of Wellbutrin. After reading other posts, I think I might try the real deal, although, I think if that if there is THAT much of a difference, the pharmaceutical companies should stop and think REAL hard about playing roulette with people's lives. M 26 3 weeks
150 MG 2X day
4/11/2010
Email
 4  depression, PMDD, PTSD, OCD I notice that almost everyone that is complaining about this drug is taking it more than once per day. My doctor has me on 100mg in the morning. He said not to take it after late morning. So far, I feel wonderful after replacing Prozac with this. I am a little on edge and can take 1mg of ativan to compensate. I have energy I have missed having for a year. I can walk a few miles a day again with the dog. I don't feel depressed at all. I feel like my normal self for the first time in 2 years. i would suggest if you are having horrid side effects to talk with your doctor about lowering the dose (as long as you are not depressed), and see if that makes the other side effects more manageable? I am also losing the weight that Prozac helped me gain. So far 5 pounds. No more night cravings or feasting. YAY! Good luck to everyone with your own personal fight to feel better!!! I am wondering about using the name brand instead of the generic? I saw one clear comment that side effects seemed to lessen with the name brand. Also, anyone on this for PMDD? I have a wonderful strict vitamin regimen that has helped my PMDD for years that I created, but I am nervous about this first cycle on a new med. F 46 8 days
100mg 1X day
4/7/2010
 2  depression extremely itchy skin and red welts, chest pains, shortness of breath, increased anxiety I stopped taking Wellbutrin over two weeks ago and still waiting for the itching to stop. Thankfully it's not as bad. F 32 14 days
150 1X day
4/7/2010
Email
 2  depression severe irritability, lack of concentration, sever changes to menstrual cycle I started with 150mg two months ago. After a week I felt worse than I did before. I wanted to commit suicide every day, instead of the couple times a year like before. The next 3 weeks were better. I had no more suicidal thoughts and had a general feeling of wellness. The following 3 weeks were the complete opposite; I was irritable to anyone and everyone for doing absolutely nothing. In addition, I went from having no menstrual cycle for a year, to having it every day for the last 8 weeks. After 7 weeks my dose was doubled to 300mg. Since then I have been in a fog, unable to concentrate on anything. When driving or even walking, I feel like I am in a tunnel. F 28 2 months
300mg 1X day
4/6/2010
Email
 5  Depression First off I was taking the GENERIC Wellbutrin 300mg XL made by Teva and had to stop it because of the horrible side effects. My moods turned from suicidal to extremely violent like wanting to kill people for them taking too long in line and throwing things at people. It also made me HORRIBLY constipated, and I have never been constipated before in my life. I couldn't sleep well and was foggy. I stopped taking it and everything went back to 'normal'. Then I heard about people taking the brand, and so I ordered the brand name drug instead (cost 40$ instead of 10$ for the co-pay) and I have not been constipated, or violent and can sleep relatively well. It is criminal that the generic is so disgustingly bad. If you have had horrible side effects from Wellbutrin try the brand name. I didn't believe it either but I was desperate since I have tried SSRIs and I felt like I had a dopamine problem and this is the only drug (minus MAOIs and some tricyclics which both have horrible side e With the BRAND name, I feel a little speedy sometimes and I don't want to eat as much and my mouth gets a little dry. All very tolerable compared with the generic's side effects. M 22 3 weeks
300 mg 1X day
4/3/2010
 2  Depression, no motivation headache behind eyes to start, dry mouth, weird taste,& tremors WITH muscle weakness, that scared me. Oh and the inevitable constipation and burping, queasy stomach. The muscle stuff is what made me go off. There never was really any benefit. Slightly better sex drive? Too soon to tell what benefits I would get from it. Was kinda bummed to give it up. F 50 14 days
300mg 1X day
4/3/2010
Email
 4  depression nervousness, dizziness, increased appetite relieves depression quickly not for anxiety though , had to take xanax too to calm down M 60 6 months
75mg 2X day
3/31/2010
 3  PTSD, Depression, and Anxiety blurred and double vision, more energy to the point of feeling "wired" and then experiencing major energy crashes, mild insomnia, appetite decrease, less anxiety at first but more moderate later on I recently started taking Wellbutrin about two weeks ago, and I've already felt a change. I don't know if it's for the better or the worse because I feel like my depression has generally been more manageable overall, as well as my anxiety for about the first week. At the start of my third week, I've felt the anxiety worsen. I feel like I am having mood swings and boughts of anxiety less than I used to, but when I do have them, they feel like they're uncontrollable (like it's not me at all). I also started taking this pill as an alternative to a sleep aid to help with night terrors possibly caused by the PTSD, and they have decreased drastically over the past 2 weeks. Besides my uncontrollable mood swings, I am also experiencing a feeling that washes over me almost instantly where I feel like I am in a foggy, day-dreaming state where I can not control it. Has anyone else experienced this, and is it possible to tell if the pills are working already or not? F 17 3 weeks
150 MG 2X day
3/29/2010
 1  depression extreme anxiety and depression. Buzzing sound in my head that would not let me sleep, had to keep tv on all night to keep the buzzing at bay! Went to another doc and he say wellbutrin was too stimulating for me. He said my problem is general anxiety which leads to depression when your brain has had enough. He put me on Zoloft and it has done wonders. Still get anxious from time to time but nothing like the old days! M 44 7 days
1X day
3/29/2010
 3  bupropion ER no side effects that I know of. I have been taking Bupropion 200 MG once a day. The first week I have noticed an up in my mood, but later on (about 4 days later) I experienced one day when I was at the gym euphoria, I was extremely happy and smiling at everyone, I was making great plans for my business and everything was fine. Later there on, I have been noticing a huge lift in my mood, and also days of severe depression and hopelessness. One day I'm happy, the next no hope at all. This really far from what I was hoping for. I think this drug is making me realize more and more that I have bipolar disorder, I haven't experienced any euphoria before the meds, but now. It's rediculous. M 23 34 days
200 MG 1X day
3/25/2010
Email
 2  Moderate depression, PTSD Greatly increased irritability and anxiety. Excessive sweating. Weight loss. Increased energy/irritability with accompanying weight loss. Did nothing for my symptoms/condition. Just been switched to Remeron. Good luck to me. M 46 8 months
100 MG 4X day
3/21/2010
 1  seasonal effective disorder It is making me anxious, can't concentrate on anything, dry mouth,can't sleep at nite-restless legs, just cry for no reason,last 3 days took 1/2 still the same. Only good thing lost weight, NO appetite I am taking what is called Alpenzen supposed to be the same as Wellbutrin. I am quiting it. It is awful, If I'm crying anyway, may as well crying without it. F 60 20 days
348mg 1X day
3/21/2010
 1  depression Did not work, depression more intense, anxiety, insomnia, irritable, emotional I was put on wellbutrin to try and fix the sexual side effects from lexapro....which I was still on. This medication made my depression basically come back. I cried for no reason, could care less about anything, and it did not come close to helping me. I got off wellbutrin after just 3weeks. I've been off it for 2 days now. Back to lexapro and things are already so much better. Id rather deal with 1 side effect with lex than spiral back into my depression with wellbutrin F 26 3 weeks
150mg 1X day
3/19/2010
 4  Seasonal Affective Disorder When I start experiencing a little insomnia, short temper and night sweats, I know it is time to start tapering off. This site is supposed to be for the direct release type, not the extended release, but it's all mixed in. I do think that it's a very good drug, but not when taken in excess. I think people might be happier if they started with a lower dose and raised it gradually until they felt normal, and then stay there. Since I take it only seasonally, I start taking 75 mg. a day in the fall when I start sliding into Seasonal Affective Disorder depression. By December I am up to 3 times a day (the most I ever take). By mid March I am tapering off, 2 on one day, 1 on the next day, then 2, alternating. By May I will be off it again until fall. F 66 90 days
75 mg 3X day
3/9/2010
 1  severe depression at 21 days suddenly uncontrollable libido, constant arousal, fantasies, increased physical activity level, feeling of happiness that was had an edge of hysteria...decrease in appetite, felt my brain was stimulated, able to concentrate more the wonderful positive effects were swamped by the uncontrollable arousal...i was constantly powerfully aroused and stimulated, always on the verge of orgasm... I had to stop taking it...it has now been a week since i stopped and i am still experiencing sexual arousal & stimulation...although i really enjoy sex usually, this is unbearable... F 52 35 days
100 mg 2X day
3/6/2010
 1  Severe Depression vicious amount of adrenalyn running through my body almost all of the time, absolutely no appetite, severe anxiety, and unable to sleep more than a couple of hours a night. This drug turned me into a jittering mess, i had an incredible amount of energy and it was not good, it made me shake and uncomfortable all the time and also severely increased my anxiety. Not even for the love of God could I get myself to relax, I felt like I was on coke or speed all the time. Eating made me feel like puking, I couldn't eat more than a spoonful or two a day and had no appetite at all. I also could not get to sleep, and was never tired! I guess it's a good drug if you wanna lose weight and get a lot of work done, but people are going to think you're an addict because you wont be able to disguise your anxiety. Apparently this drug messes with your adrenalyn levels so that explains the massive energy all the time. F 25 8 days
1X day
3/5/2010

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