AYGESTIN Reviews

Average Rating: 2.9 (151 Ratings)

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Key to Ratings: 1=LOW (I would not recommend taking this medicine.)
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More on AYGESTIN: Reviews Summary  |  Drug Safety Information

RATING  REASONSIDE EFFECTS FOR AYGESTINCOMMENTSSEXAGEDURATION/
DOSAGE
DATE ADDED
 
 2  Heavy Periods Mood swings, anxiety, decreased sex drive, bleeding, night sweats, hot flashes and headache. F 40 43 days
5mg 1X D
10/5/2021
 5  Heavy periods I started on this drug for heavy periods and pain. The symptoms cleared up right away. A great side effect was uterine orgasms, in addition to vaginal orgasms. I don't really know if it's a side effect, but I had one for the first time the first night I took the drug. I love being able to schedule my period. I get my period 4 days after I stop taking it. My periods are lighter. I did get a sun spot on my face about 2 years after starting the drug. I don't know if it's related to the drug. I also have night sweats now. I think this has more to do with me getting closer to menopause. I wonder if this drug prevents me from reaching menopause. I am 59 and still get periods. My sisters reached menopause at 52-54 years old. F 59 100 days
5 1X D
7/19/2021
Email
 2  Endometriosis I started taking this 3 days after my second laparoscopic excision of endometriosis in 1/2018. At first it was amazing, no cramps, pain, or heaving bleeding. 3 months in- gastric reflux so bad (I had previously been managing my vulnerability to reflux with diet and PPI) but this was relentless, it damaged my esophagus and I ended up having a major surgery to fix (nissen). Plus- chronic nausea, dizziness, constipation, bladder spasms, severe weight gain yet decreased appetite, rage, depression/anxiety- to the point of almost taking my life multiple times, restless sleepless nights, night sweats, chills, did I mention the RAGE, not just lack of libido but full blown aversion to anything related to sex, acne on shoulders and back . Oh- and within 1 year of starting I ended up being diagnosed with Type 1 diabetes- I assume related to my genetic vulnerability and the potential of this medication to cause hyperglycemia and extreme stress on the body (triggers for those vulnerable to T1D). I have cried and cried to my doctors (GI, PCP, GYNE, endocrinologist, and endometriosis specialists) no ONE mention that all my issues could be related to this medication, because they all said- if it were related it would have started immediately upon taking, not a few months in. I wish I had found this review site years ago. I plan to stop ASAP. I am scared, but nothing can be as bad as this has made me feel. Please reach out if you have stopped this med and let me know how long it's taken you to feel like a human being worth life again. F 35 3 years
5mg 1X D
11/15/2020
Email
 1  Endo, Focal & Diffuse adenomyosis RAGE, irregular bleeding, night sweats, depression, fatigue, anxiety, mental anguish, irritability, insomnia, weight gain, constipation, despair. Wish it would've worked. For the first two weeks I felt great and then a mental prison and rage. F 47 3 months
10 1X D
10/14/2020
Email
 2  To shrink endometrioma Nausea, headache, decreased appetite, no motivation to do anything, longer periods, no sex drive, trouble sleeping. I'm constantly having cramps and feeling sick every single day. This can't be normal. I am hoping to speak with my provider soon and discontinue this medication in the future. F 34 15 days
5mg 1X D
10/11/2020
 1  Premenopause, heavy periods Moodiness, no sex drive at all, Inability to climax, vaginal dryness- tingly arms and hands, weight gain. I live on salads and work out 4-5 days a week and can't lose the weight I gained. It did stop my periods, cramps, and breast swelling- if I wasn't married and did not care About sex, I guess it would be great. Not sure how to stop taking it. Can I stop immediately or do I need to step down? F 45 8 months
5 1X D
10/11/2020
Email
 5  Endometriosis In the beginning, nothing. I started taking Aygestin in combination with the Lupron shot to help shrink the endometriosis after a lap. surgery. I've been side effect free for 14 years! I did have some weight gain, but I will take it over the pain I was having I did great for 14 years. Now I've begun to have some very light spotting and cramping. It happened for about a week in July and then again in September. It's now happening about every other week. I'm not sure if this is a side effect of the Aygestin and that my body is just too used to it now or what? I don't know if menopause is starting (I just turned 40) or if I just need to up my dose. I did call my doc. two weeks ago and he said to just make sure I'm taking it at the same time every day (which I do 98% of the time). I've never been able to find anyone who's been on it as long as I have been to see if they have any of the spotting/cramping that I have after all this time. F 40 14 years
5mg 1X D
10/6/2020
Email
 3  Stop heavy period due to fibroid While on the drug I experienced mood swings, depression, body cramps, dark spot on face. The heavy periods stopped almost immediately (only slight spotting) which was good but all the other side effects affected my daily life. I also took one Lupron shot in the first month that I started taking the medication. Just stopped taking Aygestin about 10 days ago. Heavy bleeding, severe leg cramps, tiredness, breast tenderness started about 3 days ago. Not sure how long the effects will last. F 42 7 months
5 1X D
10/3/2020
Email
 4  Severe bleeding and hormone imbalance I was in severe pain and bleeding couldn't stand up or nothing. I couldn't function at all. Just cry in pain. It lasted for three months. Then I seen a different doctor and was put on Agestin or Norithindrone. It stopped my pain and blowing with in a day. Now I have been on it for two years and within that time, I have rapidly gained weight. I was 120 and now 171, it has caused my hair to stop growing, not sleeping good, blood pressure issues and shortness of breath. I feel as though I made a deal with the devil, he took away my bleeding and pain just to sacrifice other things. I don't feel young and beautiful and slim anymore, instead I feel as though I look like Petunia Pig. My gynecologist blamed it on my binge eating after the loss of my Husband. Not so.... my family I stopped eating for weeks. F 55 2 years
10 mg. 2X D
9/8/2020
 1  PCOS-no period Dizzy all day every day, nausea so bad it hurt my abdomen, extreme cramping, lots of clotting when my period finally came around. I did develop a few dark patches on my face as well, I would also constantly shake and be cold while on this medication. I was only able to muddle through 7 days of the 12 prescribed. It had shook up my mental health so badly that I could not continue the medication, it felt like putting myself into a prison. My mind was the prison, so depressed I was thinking of suicide and harming myself, sleepless nights for 7 nights due to heightened anxiety, then came the vigorous mood swings and rage, crying spells, and sense of being alone/worthless. Even after stopping the medication, I am still trying to repair the damage and emotional toll it did on me in just a weeks time. I would prefer to not take this medication again. I have used Provera and it has worked just fine for me with minimal side effects. F 25 12 days
5mg 1X D
9/1/2020
 4  Long heavy period Headache, chestpain for first few days, than it went away. Calf tightness but after reduce to 1 day it went away. It did stopped the bleed ing after 2 days. When I reduce to 1 day. There's spotting and light bleeding some days. The cramping was so severe for 7 days than it went away after it sheds the lining of your uterus down . And I saw tissues like Decidual cast during the severe cramping. But I don't have the severe cramps anymore. However. I don't know what to do with the bleeding since I lowered the dose. At least it's not as heavy. But will see what the doctor suggest. Might have to go with normal birth control pills to see if help. I definitely don't want surgery. If anyone has any advices how to stop this the bleeding please email me. F 48 50 days
10mg 2X D
8/11/2020
Email
 1  Endometrial Hyperplasia After one month of taking the 5 mg. pill, I suddenly felt nauseated and dizzy daily, and I began to bleed to the point where I am changing my tampon every two hours and have to use pads as a back up. Never mind the ACCIDENTS that have to be washed daily! I also have severe cramping. This has been going on for four days straight. Due to all of these symptoms, I had to take yet another medication daily for nausea and NSAIDS for the groin cramping. Who needs this? How can you live or work experiencing this misery? Mind you, I am in menopause and no longer have ovaries! The doctor was sympathetic, but I took myself off this poisonous, medical roller coaster ride! I will have a biopsy and/or D&C or surgery and go from there. Quality of life is everything! When I was on the low dose tricyclic birth control, it changed my menstrual symptoms for the better. I had no clue about the nightmare ahead. What happens when you finally get off of or take yourself off this medication? Do you actually get better? No one knows! My doctor could not tell me how much longer would have my PERIOD and associated symptoms. Do your research and take control over your health. By the way, insist on sedation if you are going to have an in-office uterine biopsy due to Covid-19, etc. It is extremely painful even though the cervix is numbed. Your doctor will have to prescribe a controlled substance. I was shocked when I had these violent symptoms after having had no symptoms for the first month I had been taking Aygestin. There is a significant list of medications that Aygestin and its generic form, norethidrone acetate, react with. Educate and advocate for yourself! F 55 30 days
5 mg Daily
6/27/2020
Email
 1  Endometrial Hyperplasia After one month of taking the 5 mg. pill, I suddenly felt nauseated and dizzy daily, and I began to bleed to the point where I am changing my tampon every two hours and have to use pads as a back up. Never mind the ACCIDENTS that have to be washed daily! I also have severe cramping. This has been going on for four days straight. Due to all of these symptoms, I had to take yet another medication daily for nausea and NSAIDS for the groin cramping. Who needs this? How can you live or work experiencing this misery? Mind you, I am in menopause and no longer have ovaries! The doctor was sympathetic, but I took myself off this poisonous, medical roller coaster ride! I will have a biopsy and/or D&C or surgery and go from there. Quality of life is everything! When I was on the low dose tricyclic birth control, it changed my menstrual symptoms for the better. I had no clue about the nightmare ahead. What happens when you finally get off of or take yourself off this medication? Do you actually get better? No one knows! My doctor could not tell me how much longer would have my PERIOD and associated symptoms. Do your research and take control over your health. By the way, insist on sedation if you are going to have an in-office uterine biopsy due to Covid-19, etc. It is extremely painful even though the cervix is numbed. Your doctor will have to prescribe a controlled substance. I was shocked when I had these violent symptoms after having had no symptoms for the first month I had been taking Aygestin. There is a significant list of medications that Aygestin and its generic form, norethidrone acetate, react with. Educate and advocate for yourself! F 55 30 days
5 mg Daily
6/27/2020
Email
 1  Heavy periods Horrible medication. I experienced abdominal cramping soon after taking this medication for the entire time I took it including severe and relentless pain in back of my calve, SEVERE mood changes including depression and rage. Doctor never told me about depression or mood change risk even though I have a long history of major depression disorder. I am stopping this drug permanently. I also had very severe night sweats that lasted the entire month I took this drug. Awful medication I would never take this again. F 48 1 months
5mg daily
6/25/2020
Email
 2  spotting im on aygestin 5mg twice a day. but still spotting. seems like its not working for me. F 41 21 days
5
5/17/2020
 1  Postmenopausal bleeding Vivid dreams, feeling depressed like it's PMS, cramps, headache, legs pain. I had bleeding/spotting before my doctor put me on these pills; it stopped but after two weeks I feel emotionally drained and did not have a good night sleep even onece. F 47 2 weeks
.5 mg 1xd
4/12/2020
Email
 3  Uncontrollable bleeding Night mares, leg pains, hip pains, all over muscle pains, headaches, night sweats, hot flashes, depression, mood swings, insomnia. I've been taking aygestin for 3 months. I started off only taking it for the first 12 days of the month. It kept my cycle regular but still had uncontrollable bleeding during my cycle. The pain was still unbearable. The nightmares started immediately. Went back to the doctor and she decided to have me take it daily 😱. The body pain, headaches and depression seem to be getting worse. I have an appointment for an endometrial biopsy in January along with several other tests. I think I would rather have the menstrual cycle complications verses the side effects. F 49 3 months
5MG
11/30/2019
 3  Heavy bleeding 5mg was way too much for my system. Heavy bleeding stopped 4-6 hours after taking 1st pill but had HORRIBLE ANXIETY and could not sleep!! Also had leg pain and shooting pains in my right arm. When coming off it I had HORRIBLE cramping and the blood was a LOT with clots. I NEVER get cramping so this was DEFINITELY because of the pill. Dr. Said I could try cutting in half. Cutting in half gave me NO SIDE EFFECTS AT ALL which is great but still spotting a little and a soon as it's time to take it again the bleeding is already getting strong again. Now trying sharobel another progesterone only pill but only .35 mg. Coming off the aygestin has me cramping bad again painfully and clots and bleeding. Will give it a day and see if this new pill can stop the bleeding..if not will to go back on the aygestin 😥 None F 43 4 days
5mg then 2
10/23/2019
Email
 1  5 week long period Hot flashes, insomnia, fatigue, irritability Dizziness started about a week into the pill. The pill did not stop my bleeding. It controlled it so that I didnít have a heavy flow but I still continued bleeding for 7 weeks. I came off of it after about 2 weeks on the pill. I think Iím still suffering the side effects and Iíve been off of it for a week. Iím extremely fatigued and dizzy. And have insomnia. Anyone have any similar effects of coming off this pill? After effects? F 39 1 days
10 mg
10/10/2019
Email
 3  To stop heavy bleeding Iím having pain in one calf. I took a step and it felt like something tore or popped inside. Not sure if itís from the Aygestin. It feels tight, like I have to keep stretching it all. This happened after being on it a month and switching to taking it every other day Day long. Has anyone else had this type of pain? I It has stopped my heavy bleeding. I still have spotting though F 53 2 months
5mg
8/3/2019
Email
  

AYGESTIN  (NORETHINDRONE ACETATE):  This medication is used to treat women with abnormal bleeding from the uterus. It is also used to treat women who have stopped having menstrual periods for several months (amenorrhea) but who are not pregnant or going through menopause. In addition, this medication is used to treat a condition (endometriosis) in which tissue that normally lines the inside of the uterus is found outside the uterus in the abdomen/pelvic area, causing painful/irregular periods. Norethindrone is a type of female hormone (progestin). It is like the hormone progesterone that your body makes naturally. This medication works by stopping the normal growth of the uterus lining during the menstrual cycle and signaling hormone changes in the uterus to restore normal menstrual periods. This medication must not be used to test for pregnancy. Progestins are not effective in preventing miscarriages.   (Sources: U.S. Centers for Medicare Services, FDA)

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