NOLVADEX Reviews (TAMOXIFEN CITRATE)

Average Rating: 2.7 (115 Ratings)

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 ANTINEOPLASTICS

 Type: Rx Drug

  

NOLVADEX  (TAMOXIFEN CITRATE):  Tamoxifen is used to treat breast cancer. It is also used to reduce the chances of breast cancer in high-risk patients. This medication can block the growth of breast cancer. It works by interfering with the effects of estrogen in the breast tissue.   FDA Approval Date: 1994-03-21 (Sources: U.S. Centers for Medicare Services, FDA)

  

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Key to Ratings: 1=LOW (I would not recommend taking this medicine.)
5=HIGH (this medicine cured me or helped me a great deal.)

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More on NOLVADEX: Reviews Summary  |  Drug Safety Information

RATING  REASONSIDE EFFECTS FOR NOLVADEXCOMMENTSSEXAGEDURATION/
DOSAGE
DATE ADDED
 
 2  Low Grade Ovarian Cancer Weight Gain, Terrible Sleep problems, sleep deprivation, anxiety, depression dryness, It did slow the progression of the tumors. It was hell. F 36 8 months
3/18/2006
 2  Breast Cancer - Stage 1 Hot flashes and night sweats at first which subsided after a couple of months of being on the drug. After about 5-6 months, I started noticing my memory failing and feeling like I was foggy a lot, which progressively got worse (my family even noticed!). I went off of it for a month and the side effect subsided. My doctor then switched me to Arimidex. F 40 11 months
3/15/2006
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 1  post mastectomy for BrCA Male. Yeah, that's not a mis-click. Leg weakness & knee pain (couldn't get out of a car without hauling myself up); brain fog Was switched to aromatase inhibitor. Luckily I have a drug plan. It's all guesswork for guys with BrCA. Not enough of us in one place to put together for any studies. Until then, we're just like women. M 60 4 months
12/5/2005
 1  To prevent recurrence Anxiety, increased vaginal secretions, constant sense of pressure in the uterus. Slept badly most nights. Knee joints hurt constantly. I already had an ovarian cyst removed during my second pregnancy. I didn't need to worry about getting cancer of the uterus on top of worrying about recurrence. Also I was worried about tamoxifen being toxic to my liver in the long run. I stopped after 5 weeks. Felt immediately better. Am now on Arimidex. F 49 5 weeks
8/30/2005
 1  Quite advanced breast cancer Hot flushes, but less vaginal dryness than I had on Lupron (known as Prostap in the UK). It didn't control my (very oestrogen sensitive) cancer - the metastases in my liver got worse, and the cancer in my lymph nodes got worse - and I seem to have got cancer in my right leg as well, in the bone (femur). Also, a scan detected a Didn't work for me. I was right to avoid it in the first place. I tried it as an alternative to Lupron, but it seems it had adverse effects on my uterus. 48 6 months
5/10/2005
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 1  Quite advanced breast cancer Hot flushes, but less vaginal dryness than I had on Lupron (known as Prostap in the UK). It didn't control my (very oestrogen sensitive) cancer - the metastases in my liver got worse, and the cancer in my lymph nodes got worse - and I seem to have got cancer in my right leg as well, in the bone (femur). Didn't work for me. Also, a scan detected a 48 6 months
5/10/2005
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 1  Advanced breast cancer Why is this site not showing my whole message ? It keeps cutting out the last part ... I wanted to mention that the drug caused a large UTERINE FIBROID, which I had NEVER had before. Didn't work for my (very oestrogen sensitive) cancer. Side effects on womb. I found Lupron (Prostap) to be better. F 48 6 months
5/10/2005
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 4  prevent recurrence of breast cancer hot flashes (very mild and few, maybe 3-4/day) F 50 1.5 years
3/13/2005
 3  Stage 2 breast cancer Vaginal dryness, infrequent leg and back cramps, weight gain (or at least that's what I'm blaming it on) My onc wants mt to switch to one of the newer AIs when I get to 2 years on Tamoxifen. Since Tamoxifen's been pretty easy for me, I'm nervous about the switch. However, I'll take anything to keep recurrance away! F 58 18 months
3/13/2005
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 4  breast cancer loss of sexual interest, ovarian cysts, diarhea, hot flashes. Have started getting Zoladex shots to counter-act the continous problem with ovarian cysts. Hate that one med leads to another..... F 39 2 years
1/26/2005
 2  breast cancer Fatigue, achy joints, cramps, weight gain. I stopped taking it for one month and felt a lot better without it. I don't feel healthy when I take it. Of course, there's no way to know if it's really working. I continue to take it hoping to stay cancer-free. F 44 14 months
11/2/2004
 4  breast cancer The side effects that I experienced were not too bad. I had "hot flashes" fairly often. I stayed on it for my designated five years. Unknown to me, my radiologists were watching "somethings" in my liver for two years. Two months after I got off of the Nolvadex, we discovered that I have 5 cancerous tumors in my liver. They began to grow more after I got off of the Nolvadex. Now I am on Arimidex. I've been on the Arimidex since March and so far the tumors have not grown. F 49 8 months
10/24/2002
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 4  Multifocal lobular carcinoma insitu Hot flashes, water retention, weight gain, vaginal dryness and all over skin dryness After about 2 years the hot flashes decreased in intensity. I also take trazadone to help with the hot flashes and am now taking Dyazide to help with the water retention F 52 3 years
10/14/2002
 1  Breast cancer - 2nd reoccurence I started to take Tamoxifen in April 2000. At that time I was having some perimenopausal symptoms but was having normal menstrual periods. From that point on I had bleeding every January, May and August, somewhat like a period. After each of these bleeding episodes, I had a pelvic ultrasound which showed ovarian cysts and once some thickening of the uterine wall. In May, 2002 I experienced severe cramping (something like early labor pains). These lasted for 2 days. On the 3rd day I contacted the oncologist and shortly afterwards had a clotty hemorrhagic discharge. I ended up in the ER having an ultrasound. It showed a mass in the uterus. The following D and C and hysteroscopy resulted in no abnormal tissue. At that point my doctor took me off Tamoxifen and I am now on Arimidex, which so far has been working well. There are a lot of risks with Tamoxifen. With a maternal grandmother dying of uterine cancer, I don't think it was right for me. Also I have read research that patients on Tamoxifen with Ductal Carcinoma in Situ have more side effects than other cancers. This was the case with me. F 52 2 years
7/12/2002
 1  recovering from breast cancer I started vaginal bleeding again, after having gone through menopause 1 1/2 years earlier. I had adenomyosis. I had chemical depression. I was not a candidate for this drug. I had too many side effects. F 54 8 months
6/6/2002

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