NOLVADEX Reviews (TAMOXIFEN CITRATE)

Average Rating: 2.7 (115 Ratings)

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 ANTINEOPLASTICS

 Type: Rx Drug

  

NOLVADEX  (TAMOXIFEN CITRATE):  Tamoxifen is used to treat breast cancer. It is also used to reduce the chances of breast cancer in high-risk patients. This medication can block the growth of breast cancer. It works by interfering with the effects of estrogen in the breast tissue.   FDA Approval Date: 1994-03-21 (Sources: U.S. Centers for Medicare Services, FDA)

  

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Key to Ratings: 1=LOW (I would not recommend taking this medicine.)
5=HIGH (this medicine cured me or helped me a great deal.)

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More on NOLVADEX: Reviews Summary  |  Drug Safety Information

RATING  REASONSIDE EFFECTS FOR NOLVADEXCOMMENTSSEXAGEDURATION/
DOSAGE
DATE ADDED
 
 4  breast ca hot flashes, weight gain not too bad F 43 1 years
20mg 1X day
2/1/2011
 1  breast cancer Some hot flashes. I cannot tolerate it as I am desperately trying to take it every other day, and it is making me manicky. I have made three attempts. Also, some loss of hair. However, the anxiety is off the chain. Feel like I'm taking amphetamines. F 47 2 weeks
5 mg 1X day
1/22/2011
 3  breast cancer Stage 3 mastectomy Have posted previously at 2-year mark. At 3 years, my fatigue became so bad, I asked oncologist if I could take a break from drug as I was unable to function. He agreed; said many women do. I have only been off less than a week, but am beginning to notice some slight physical and emotional changes. Will think about going back in 2-3 months. BUT, if you are suffering -- use your common sense and ask your doctor if a "break" is do-able. F 61 3 years
20 1X day
12/6/2010
 2  Breast cancer, stage 2 Took arimidex for 15 months, changed to tamoxifen for 6 months, still have side effects. Are now choosing fate. Unfortunately, had all side effects. Worse was the loss of short term memory, was in corporate position, now have trouble with what day it is, funny, I leave my diary beside me to remind me of what has to be done!!!! Oh, an what day it is. I don't work now, not possible, but maybe again in the future. I was a gym junkie, very fit, now, my bone density has decreased and taking the supplements, my joint pain is excruiciating, I have bad arthritis and everything that goes with that. But as I have mentioned its all about the brain, and that I cannot tolerate, and if my life is cut short, so be it. There is not enough research to justify the anguist. Why should 55 weight take the same medication as 95, why isn't there research for amounts of toxins we put in our bodies? We have supposed to have come along way, but you know what, your alive just take it!!! Think yourself lucky.. F 50 2 years
20 1X day
11/19/2010
 3  stage II breast cancer Extreme tiredness 9 out of 10 days, can barely function at work. Extreme hip pain; it sometimes feel like my legs are being pulled off. Started taking 12,000 iu of Vitamin D3 per day, that finally helped more than any other remedy for the hip pain. Still have excruciating heel pain, and feel achy in the morning. Zero sex drive, it's just gone. I feel bad for my husband, but just cannot make myself be interested. Fuzzy, foggy brain. Can no longer add or spell! I sometimes fantasize about going off this drug, but really don't want to have cancer again. My quality of life these past few years hasn't been much, but it's better than the alternative. I am grateful to be here to watch my daughter grow up, even if it's been hard. F 44 3 years
20mg 1X day
10/14/2010
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 5  Breast Cancer Mastectomy I tolerated Nolvadex well for 4-1/2yrs; no noticeable side effects. I felt happy & energetic. There's history of blood clots (strokes) in my family & Dr didn't want to put me on TAMOXIFEN because of that. ARIMIDEX has lower occurrence of blood clots, but I struggled with extreme side effects on Arimidex for 6mo. & it was crippling me with severe joint & bone pain all over my body. At the 5 yr mark Dr tried FEMARA & was on that for 5yrs very successfully. Few noticeable side effects other than thinning hair & weight gain. At 10yr mark Dr took me off of everything (6mo ago) except annual iv for ZOMETA which I also tolerated well. Dr switched to RECLAST & I have joint pain & bone pain from that. I attribute my 10yrs in cancer remission to TAMOXIFEN, FEMARA & GOD. All drugs have side effects, even Tylenol, so I don't read the side effects that the pharmacy puts in with the medicine, I just want to do anything I possibly can to give my body a fighting cha F 76 4 years
1X day
9/24/2010
 4  As a Precaution after Radiation No side effects thus far. I have not experienced any side effects in the two weeks that I have been taking it. I am hoping I do not. Although he did say that my body will not absorb tamoxifen but will give it a shot for 1 month. If things don't change I will have to get my ovaries taken out. F 43 2 weeks
2 cm.. 1X day
8/18/2010
 3  Stage 2a breast Cancer, node neg. Hot flashes, not too bad because I'm on an antidepressant. Occassional leg cramp and hip pain. A little brain fuzzy, but not all the time. Some days I'm extremely clumsy, very strange. Weight loss is extremely difficult. Sometimes I suddenly become so tired I can hardly keep my eyes open. I take it at night and that helps a bit. I was on Arimidex for about 5 months. I had shoulder tendonitis and bad tendonitis in my wrists. Things were so bad in my hands I could hardly use my right hand. Have had multiple shots in my writsts to calm things down.Went off the drug for 2 months. I told my doctor I was getting off it. Then went on Tamoxifen. Side effects so far aren't anywhere near what the Arimidex caused. F 54 6.7 months
20 mg. 1X day
8/10/2010
 1   Searing pain, right hip - generalized hip pain most of the time, especially in the morning - I felt like I was 85 instead of 55. Pain and stiffness in left hand. Depression, fatigue, weight gain. Not worth it for DCIS. Quality of life on a slow decline. F 55 500 days
20 mg 1X day
7/28/2010
Email
 5  Breast cancer stage 1 Minor hot flashes. Some vaginal discharge. Period was regular for 2 years but in the 3rd year, I started getting super light periods sometimes skipping a couple of months. Some loss of libido...it comes and goes. Other than that, I tolerated it well. F 51 3 years
20 mg 1X day
6/12/2010
 3  breast cancer stage III Initially very few side effects except "hot flashes," which were bearable; However at 2-year mark noticed substantial memory loss -- inability to form words; also noted an emotional "flatness" Recently have had shortness of breath -- fluttery feeling in chest. Was far better than aromatose inhibitor (although I had gone through menopause at age 51). F 60 2 years
20 mg 1X day
4/14/2010
 3  Breast Cancer Stage 2 Severe hot flashes & night sweats,about 10 a day,Vaginal dryness.Not had a Period since last chemo (nov 09)thats prob chemo & not tamoxifen. I think its worth it for my future health,but its early days.I have found drinking ice cold water when having a hot flash helps. F 35 6 weeks
20mg 1X day
3/9/2010
 2  breast cancer hot flashes, hair loss, memory & cognitive difficulties, joint pain M 53 2 years
1/17/2010
 3  Breast cancer Hot flashes, cold flashes, vaginal dryness, vaginal atrophy. Fatigue. Cognitive issues. Initially some vaginal discharge, but that went away after a few months. Although those are a lot of symptoms, so far (after 8 months) it is doable. No symptom is too severe. I was found to be (genetically) an "extreme metabolizer". F 51 8 months
11/23/2009
 3  breast cancer fatigue, pain especially in feet and hands, depression, hair loss, occasional mild hot flashes It isn't too bad being on tamoxifen but would be interested in having a break from it to see if some of the side effects lessen. F 52 2 years
11/11/2009
 1  stage 1 estrogen fed cancer Confusion, tiredness beyond all means, lack of interest in doing anything. First I was hyper then tired. Felt drugged when taking it. Plus I had to constantly get up and go to the bathroom during the night. I am not happy taking this drug. I need to be able to work and Tamoxifen is not going to let me. I took Arimidex and that was bad too. Will check with the oncologist for something else. F 57 3 days
10/4/2009
 4  Stage 1 BC, Bi-lateral Mastectomy None so far although weight gain looks like it might be an issue. I am exercising and watching what I eat but am not losing. Feel blue....but that could be because my baby just left for college and I miss him. When my oncologist first spoke of taking tamoxifen I did not want to do it because I was still feeling crappy from my surgery. He said that my risk was small (because i had a double mastectomy) so my benefit would be small. However, the thought of a reoccurrence is truly terrifying so I decided to give it a go and I've been lucky so far. It's only been 54 days so I'm still a newbie to the drug but I am hoping for the best. I can't say whether the med is helping me or curing me....that remains to be seen but it is what I am hoping for! F 47 54 days
9/23/2009
 1  Breast CA Stage II, 1 positive node For the first five months on Tamoxifen I experienced only hot flashes and vaginal discharge. The hot flashes have been severe. I would be constantly breaking out in a sweat and feeling as if I was on fire. Breaking out in a sweat ten times during a shift at work was very inconvenient and uncomfortable. I was soaking through my clothes. These sweats and hot flashes interferred with sleep. I was only able to sleep for short periods and then would be awake the rest of the night. I couldn't get comfortable. After five months I began developing arthritis in my hands. My left thumb has been very painful now for four months. Both hands feel stiff and hurt. I also had transient joint pain in the lower back, hips, and shoulders. Around this same time I began having terrible fatigue. I was a marathon runner when I was dx'd with cancer and continued to run through the chemo and before and after my mastectomy/reconstruction surgery. During months 6 through 8 on Tamoxifen, I began to After three weeks without Tamoxifen, I feel so much better. I didn't even make it a year on Tamoxifen. I went into this with an open mind believing in the importance of taking it. It seems to me that the damage Tamoxifen can cause due to short and long term side effects is SIGNIFICANT. My question is why are the drug companies and the doctors reinforcing the idea that side effects are minimal to noexistent? If they lie about this then why should I have any faith in their so-called studies? F 48 8 months
9/22/2009
Email
 1  Breast cancer prevention Hot flashes that had no flash -- just extremely HOT ALL THE TIME! I had to sleep with ice packs. It felt is if my blood was boiling inside of me and my fingers felt like they were about to explode. I was just miserable the entire time I took it. When I stopped taking Tamoxifen, everything got much better. F 51 4 months
8/17/2009
 4  Post-breast cancer treatment Hot flashes; nothing else significant I began tamoxifen following mastectomy and radiation. Quite frankly, reading some of these reviews had me scared to death. My doctor, pharmacist and another breast cancer patient assured me that severe side effects weren't common and I'm glad that I listened to them. I'm blessed in that my side effects have been minimal and the drug is not bothering me. It's important to realize that the chemistry that makes up our bodies is different and that bad side effects exist with some patients and not others. So, keep an open mind if you're going to be taking the drug and go in to it with a positive attitude. I'm confident that this drug will help prevent recurrance of the cancer in my body. F 45 5 months
8/14/2009

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