MEGACE Reviews

Average Rating: 3.5 (62 Ratings)

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 ESTROGENS PROGESTINS

 Type: Brand name discontinued; available as generic
  

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Key to Ratings: 1=LOW (I would not recommend taking this medicine.)
5=HIGH (this medicine cured me or helped me a great deal.)

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RATING  REASONSIDE EFFECTS FOR MEGACECOMMENTSSEXAGEDURATION/
DOSAGE
DATE ADDED
 
 4  Heavy bleeding due to fibroids Had issues with heavy bleeding and cramps due to fibroids dr put me on this medication until I can have a biopsy the end of the month...took 3 tabs yesterday and the bleeding completely stopped....as I read all the ladies side effects I will.pay close attention..praying that o won't have any side effects being as though I am leaning towards have a hysterectomy F 46 2 days
40 mg 4X D
9/3/2021
Email
 5  Endometrial Cancer Irritability and hunger I was on Megace for uterine cancer. I was diagnosed early with stage one uterine cancer when I was 34. I had not had children yet and was hoping to conceive still. My doctor said we could try this medication before doing a hysterectomy since my cancer was a low grade. I was also in the middle of a weight loss journey so the side effect of weight gain freaked me out. I was on Megastrol for 6 months and beat uterine cancer with this drug. Additionally, with a strong mental attitude, I was able to work out and lose weight on this medication and did not let myself over eat. I highly suggest taking Megace on a full stomach. I am almost 36 now and currently pregnant with a baby girl. I was desperate for stories like mine, but could not find any when I went through all of this. If you are in a situation like I was, do not give up hope. You got this!! F 34 6 months
160 Mg 1X D
4/8/2021
 2  Complex Hyperplasia w/Atypia Leg cramps/Tension in calfs, tiredness, nervousness, cramping, increase hunger, excessive night sweats (literally waking up soaked), slight increase in blood sugar and blood pressure, irritability, insomnia I'm supposed to be on this medicine for 3 months and I'm not sure I can do it. It is really interfering with my quality of life. The side effects suck. I really don't want a hysterectomy, but I am leaning that way due to the side effects. F 38 2 weeks
40 1X D
3/22/2021
Email
 3  Endometrial Hyperplasia Hunger, headaches, frequent night urination, fast heart beating, extreme thirst, extreme low sex drive, mood swings Taking megace 40mg (4 tablets) twice a day. I do not want a hysterectomy. I want a baby. I've been married for 6 years now. I just turned 30 years. F 30 9 months
40 2X D
10/27/2020
Email
 4  Endemiotrios cancer Side effects no sex drive cramping bleeding sometimes. Cramps occasionally. Megrace has actually helped me get rid of my endometriosis . F 37 7 days
40 1X D
9/23/2020
Email
 5  Weight gain No period, very thirsty and hot flashes I started taking this medicine 6/23/2020 I was 115 now Im 134 on 7/17/2020 F 32 1 days
10ml 1X D
7/16/2020
 4  Weight gain The only side affect i am having is bloating after i eat, period havent came on yet and eating like a pig. And alot of stomach cramps F 31 4 months
40 mg
6/28/2020
Email
 5  Weight Gain No side effects that I've noticed besides being hungry all the time. I have to be careful and eat in moderation otherwise I'm bloated from eating too much food. I absolutely love this medication as I've had colon cancer and from that I've lost my appetite for 3 years. I've gained 10 pounds in 2 weeks and I'm so thankful this is working. F 40 2 weeks
6/8/2020
 1  Clotting heavilt Bad cramping big clots fast heart beat shortness of breath If dont work F 54 100 days
20 mlg
5/10/2020
Email
 3  Endometrial cancer Night sweats, chronic fatigue, severe headaches, low sex drive, increased appetite, insomnia, moodiness, anxiety, irritability, shortness of breath and increased heart rate I was diagnosed with stage 4 endometrial cancer ivb and was prescribed Megace after 6 rounds of chemo and remission F 48 2 months
40mg 4xs d
5/2/2020
 3  Gain weight Extreme night sweats, urinating frequently into the night. My hair is coming out by the handfuls. Now I need to find something for my hair and quit taking F 64 0 weeks
10 mil
3/12/2020
 1  Undiagnosed excessive uterine bleed Severe depression,muscle cramps,tiredness,fatigue,no sex drive , mood swings , abdominal cramping. After 30+days of very heavy bleeding /clotting ,the doctor prescribed and the first week it slowed it but it has come back and for the past three +weeks , due to the horrible side affects I decided to stop taking it yesterday calling the doctor today to see if I have other options . I have never in my life felt this depressed and it is due to this medicine . F 50 0 months
60per day
12/23/2019
Email
 1  Fibroids causing Heavy bleeding Extreme weight gain; 4 sizes larger in 5 months. Back aches, sweating, hot flashes, increase in blood pressure, shortness of breath, insomnia, depression, isolation, always feel bloated, headaches, stomach upset, muscle aches. Extreme weight gain infuriates me! I was always the girl with a nice figure, completely changed my body type in 5 months of use. Lead to hurtful comments and criticism from people. I believe this drug slows down your metabolism. You could very well become obese if you're aleady over 150 lbs. I'm very dissatisfied and disappointed in the doctor for not better informing me of the trade off to stop the bleeding. Not worth it!! Will probably take me a year to drop the weight gain. I cry everyday because i miss who i was before Megase ruined my beautiful figure. Even my relationship with the guy i'm dating is in jeopardy because of my appearance i avoid seeing him. F 38 5 months
20 MG
11/30/2019
 5  To gain weight Frequently peeing, gain a lot of weight, hot flashes, night sweats. I have gained 23lbs in 3 months. I'm 4"11 and I weighed 88lbs at 43yo. I needed to eat more daily and my doctor put me on megestrol and it's been a life savor for me due to gaining the weight. I eat all day long. It's a great medication but I'm scared of what's to happen when I stop taking megestrol A F 43 3 months
40mg
10/15/2019
Email
 1  Fibroids/ Uterine bleeding Bleeding would stop then I would spot then heavy bleeding with large clots. Dr. Has to be unqualified because she would tell me take more went up to 350mg per day. Ended up with blood clots in my lungs and legs and chest pain now Iím on 40 mg twice a day along with injection of blood thinners fearing for my life at this point 3 hospital stays in a month the first in icu. I just want to live and Iím still bleeding heavily with clots some days. Praying for a miracle to save my life at this point😢 Do not take this medication but everybody is different F 43 4 months
20mg
8/23/2019
Email
 1  Needed progesterone after surgery Gas, bloating, fatigue, weight gain of more than 15 lbs., Swollen hands and feet, indigestion, heart rate and no both increased. Had some feelings of pregnancy too. Wish my doc had been upfront with me about this drug. I was told I was being put on progesterone. F 46 0 months
40mg
1/5/2019
 1  Uterine polyps Still bleeding, shortness of breath, headaches, thirsty, moodiness like blowing up at kids( not normal for me) , severe irritability, leg cramps, insomnia, extreme hunger... like never full ever! I was ok except shortness of breath for first few weeks, then my symptoms seemed overwhelming after first month. F 44 2 months
40
12/10/2018
 4  Can not gain over 91 lbs at 39 yrs. Extreme night sweats...hair thinning...gas.. diarrhea...if I skip two days I get migraine...I spotting daily for 15 days...frequent urination.... F 39 2 years
10mg
9/27/2018
 4  Complex endometrial hyperplasia w/o Hunger, fatigue, spotting At 1st i had hunger and fatigue. I however did not gain any weight (actually lost weight) because i kept mindful of what i was eating and how much. (As im trying to lose weight) i went 3 nonths on this pill with no bleeding. My 4th month im having spotting (4 times but not consecutively) it makes me worried. What if its not working? I need to have my biopsy done but i cant afford it right now. (Long story) im 30 years old. I have no kids but am getting married next month and we want to start a family. It also worries me about fertility. I hipe to get my biopsy in the next month. Im just scared its not working after spotting. F 30 4 months
80
7/17/2018
Email
 5  Ensometrial stromal sarcoma Hot flashes- increased uncontrollable hunger- night sweats- hair thinning F 48 8 weeks
160 mg
1/18/2018
  

MEGACE  (MEGESTROL ACETATE):  Megestrol is used to treat loss of appetite and weight loss in people with AIDS. Improving your appetite and gaining weight may help you feel better and be more active. Megestrol is similar to a natural substance made by the body called progesterone.   (Sources: U.S. Centers for Medicare Services, FDA)

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