MACRODANTIN Reviews (NITROFURANTOIN, MACROCRYSTALLINE)

Average Rating: 2.1 (129 Ratings)

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 ANTIBACTERIALS, MISCELLANEOUS

 Type: Rx Drug

  

MACRODANTIN  (NITROFURANTOIN, MACROCRYSTALLINE):  This medication is used to treat or prevent certain urinary tract infections. This medication is an antibiotic that works by stopping the growth of bacteria. It will not work for viral infections (e.g., common cold, flu). Unnecessary use or overuse of any antibiotic can lead to its decreased effectiveness. Nitrofurantoin should not be used in children less than one month of age due to the risk of a certain blood problem (hemolytic anemia).    (Sources: U.S. Centers for Medicare Services, FDA)

  

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Key to Ratings: 1=LOW (I would not recommend taking this medicine.)
5=HIGH (this medicine cured me or helped me a great deal.)

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More on MACRODANTIN: Reviews Summary  |  Drug Safety Information

RATING  REASONSIDE EFFECTS FOR MACRODANTINCOMMENTSSEXAGEDURATION/
DOSAGE
DATE ADDED
 
 1  kidney infection scarring of the lungs F 60 36 days
1X day
9/8/2010
 1  UTI I have chronic eosinophilic pneumonia as a result of Macrodantin I took 20 years ago. It causes recurrent episodes of shortness of breath, chest pain, productive cough, low-grade fever. I have to take corticosteroids with every exacerbation and am now being placed on them as a maintenance dose. My lungs are damaged and irreparable. It is incapacitating when I have symptoms. Corticosteroids cause problems of their own. F 46
1X day
8/9/2010
 5  3rd UTI in 12 weeks I was in the worst ever pain you could imagine, and I swear I would have taken anything... Within 1 hour after taking the first tablet, the burning had halved... By this morning hardly there at all... had diarrhea but seems to have cleared up now. Will keep you updated again soon F 54 2 days
100 mg 4X day
7/30/2010
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 1  acute bladder infection i was given macrodantin by the hospital who diagnosed with acuse bladder infection, within an hour of taking it I had the worst head ache i had ever experienced in my life In fact I thought i was going to die. The doctor told me it was the pill fighting the infection, but I knew it was the pill. I felt if I took another i would die. The pain left me with a vice like feeling and sensitive head and face for 3 days afterwards. I have since suffered migraines, and worryingly after reading this and a year later have been back and fore the doctors with numbness. My thoughts are. . try another It cleared up the infection almost after one tablet, I think it was just way too powerful for my system. F 39 1 days
2X day
7/22/2010
 1  UTI Difficulty breathing - even bought ashma pump. Pains in legs - thought is was associated with recent flu. Only when rash appeared on arms and legs did I suspect allergic reaction. Ceased medication 36 hours ago and all symptoms have disappeared. I have been prescribed 42 days' medication (one 50 mg capsule per day). Obviously I will never touch another such tablet. Thought I had onset of Guillaine Barre syndrome! F 62 7 days
50 MG 1X day
5/26/2010
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 1  URINARY TRACT INFECTION MY MOTHER DIED AS A RESULT OF LONG TERM MACRODANTIN DOSE. FEMALE DOCTOR FOUND TO BE NEGLIGENT BY MEDICAL BOARD AND HEALTH RIGHTS COMMISSION AFTER 4YRS. NO JUSTICE IN THIS WORLD - STILL PRACTISING AT THE GOLD COAST 19TH AVENUE SURGERY AND STILL ALIVE. BEWARE F 56 8 years
30 1X day
5/10/2010
 1  Urinary Tract Infection I took ONE tablet at 15h30. At 19h30 I suddenly became ill - shivering uncontrollably as if with fever; headache; pains in legs; pains in chest. Condition worsened quickly - I was finding it very difficult to breathe. Also experienced nausea and vomiting. Cotton mouth - difficulty speaking. Sudden, heavy phlegm on chest. Was rushed to emergency where I was diagnosed as being in severe anaphalaxis. Antihistamine was administered via IV - took 2,5 hours to stabilise. Doctor also thought I had bronchitis or early pneumonia - but this is not possible as it came on extremely suddenly. Later confirmed it was caused by the drug!! My doctor was shocked at my reaction to the drug. He says in all his years of practice, he has never had a patient show signs of allergy to the drug. F 72 1 days
4X day
4/14/2010
 1  UTI Took one pill of the generic form in evening after dinner. During the night I felt numbness in my feet and arms/hands which awakened me. When I awoke I was spinning dizzy and had diffucltiy speaking clearly. I reported to doctor and most effects seemed to have worn off. I am very concerned. I took this many years ago in college and I was fine but lately I have had a few situations where I am hypersensitve to meds. It's been 2 days and I'm still feeling strange-dizzy again in the morning, conscioues and aware one eye sees close the other far, etc. I am expecting this will all go away but wonder what is in it that causes this quick reaction so that I can avoid it in the future. Beware if you have sensitivities. F 56 1 days
1/31/2010
 1  UTI Within 24 hours terible pain in right side of stomach - my firt time on this drug - (usually macrobid with no problem) - so bad my doctor ordered an ultrsound of abdomen on day 4 and found nothing wrong. I ended the drug on day 5.5 not day 7 as ordered, on advice of my gyno as I was in for my annual -( drug was prescribed by my internist) It has been a week and I am sitll in pain - feeling of fullness after eating tiny amounts - next week I have to go see a gastroenterologist for a scope of the inside of my stomach if pain does not go away after being off the drug for several days. I will never take this drug again but it did stop the UTI symptoms in one day The side effects warned of are all about lung problems - the stomach pain on the right side should be investigated. I see others on this site mention right side pain. F 68 5.5 days
10/10/2009
 2  severe UTI into kidneys Nausea non-stop, headache, a feeling of being ill but not sick, cotton mouth, 4th day into treatment started feeling deep depression and anxiety. Quit the 7 day treatment half way through day 5. Macrodantin cleared symptoms within 24 hours and I had relatively no negative side effects the first few days except headache and nausea. The onset was fast and overwhelming on day 4 though. Would not recommend taking longer than a few days. This is my 2nd day off the medicine and I still have bouts of deep depression and anxiety. Will never take it again. F 43 6 days
10/3/2009
 1  To prevent UTIs after intercourse. Non-stop diarrhea and stomach upset. I took it about 3PM and by 5:30 my stomach started getting very gassy and painful. By 6:00 I had horrible diarrhea that lasted all night, and continued into the morning--still waiting for it to go away. I only took that one pill, but so far every I eat just runs right through me. :( There's no way in hell I'm taking any more. F 25 1 days
8/8/2009
 4  urinary tract infection none worked quickly to get rid of pain F 40 3 days
5/23/2009
 1  bladder infection severe fever, chills, difficulty breathing & pain in chest. Tingling in hands/feet. Severe pain low down in stomach F 50 1 days
4/8/2009
 1  UTI tingling in hands and feet; sweating; tightness in chest; shortness of breath; coughing; feeling like i was about to die Took this drug many times for UTIs with no ill effects (3 day course many times over several years). The side effects crept up on my slowly each time I took it, never made the connection. Until one day -- Boom! DO NOT TAKE THIS DRUG. Pharmacist said I had an anaphylactic reaction. If you even think of taking this drug, look it up in the PDR first, it will tell you that chronic use of this drug will cause this type of reaction. F 48 3 days
2/20/2009
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 1  urinary tract infection This drug was prescribed to me after exploratory surgery to find out why I was getting recurrent "urinary tract infections" I reacted acutely to this drug. First symptoms: a massive depression within three days, then the feeling that my body was rapidly shutting down, almost program by program like a computer about to crash. The hospital emergency unit did not know what was wrong with me - I think they suspected creational drugs! And still I gor sicker. Finally, by end of day four, when I felt I was really staring death in the eye, I suddenly, in a moment of lucidity clicked that it was the macrodantin. Even after a detox fast (lots and lots of water) it still took me almost six months of therapy and acupuncture treatment to finally get back to a normal life. The therapy was to help me deal with the immense anger and sense of betrayal I experienced against the prescribing doctor, who basically laughed my problems off, even though I pointed out that the drug was speciffically unsuited to three conditions I had. In fact - I never had a urinary tract infection. I actually had infected kidneys! F 62 4 days
4/12/2008
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 5  recurrent cystitis none pain and frequency gone within 8 hours F 61 5 days
6/29/2007
 1  UTI Horrible cough and congestion like pneumonia..Severe diarrhea, abdominal and bladder pain, numbness in my hands, arms and legs, insomnia, anxiety, vomiting and headache. I'VE NEVER FEEL SO SICK IN MY LIFE! I'VE BEEN TAKING IT FOR 8 DAYS FOR URINARY TRACK INFECTION BUT I'M GETTING WORSE, LIKE I'M ABOUT TO DIE..THEY SHOULDN'T PRESCRIBE IT! F 48 8 days
4/21/2007
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 1  Recurrent UTI's Peripheral Neuropathy (numbness, tingling in feet, nerve pain), fatigue, dizziness, pains in my sides. Many times the UTI's came back. I had a bronchitis type cold when I took this drug this last time and it has taken me longer to get over it than normal. I would never recommend this drug to anyone. I have taken this drug many times in my life, sometimes a year at a time for UTI's maintenance. But after this last time, I noticed that my Peripheral Neuropathy got worse. I researched my medical records and found that after taken this drug I soon complained of Neuropathy problems and all over pain that the doctor blamed on fibromyalgia. I think that it was this drug that cause it. I will never take this drug again! I also found out that sometimes this drug did not clear up my UTI's and had to be put on a different antibiotic. Take it from someone that has had many experiences taking this drug; don't take it! F 53 32 years
2/19/2007
 1  bladder infection Vomiting, the beginnings of yellowing of eyewhites, and huge hives on my legs. Went to the ER and was told i had the beginnings of liver shutdown. My mother took it and had the same reaction to it. Neither of us have any other med. allergies. I guess our reaction was unusual, but please be careful if you take it. F 22 6 days
9/16/2006
 1  chronic urinary tract infections Do NOT take this drug. It killed my mother at the age of 66. Her doctor left her on it for over a year. It's listed on her death certificate as the cause of death. . F 40
7/8/2006
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