Average Rating: 2.1 (127 Ratings)

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 Type: Rx Drug

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Key to Ratings: 1=LOW (I would not recommend taking this medicine.)
5=HIGH (this medicine cured me or helped me a great deal.)

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More on MACRODANTIN: Reviews Summary  |  Drug Safety Information

 1  kidney infection No one should be taking this drug. I was prescribed this for kidney infection when I have chronic kidney disease on 22/4/21 I will be alerting doctor who prescribed this that they nearly killed me. Was prescribed dosage of 100 mg 4 times a day, for 7 days. Took it till 27/4/21. Made me feel like I was dying with extreme chills and fever, excruciating back pain, whole body aching, diarrhoea, abdominal aching, gave me asthma and filled my chest with fluid, was very weepy, extreme anxiety, difficulty walking - felt like walking through cement, dizzyness, retained fluid and dropped my kidney function significantly. Was too sick to realise it was the tablets until last day, stopped them and went to another doctor 28/4/21, who wanted me to go to hospital to go on IV etc. Stopped taking the tablets, started a different antibiotic yesterday 28/4/21 and have started to feel better already. Should not be prescribed to anyone F 56 6 days
100mg 4X D
 1  UTI On generic brand grey capsule. Joint pain, no energy, brain fog, horrible anxiety/crying, muscle aches Have never written a drug review in my life but this was one tough ride and I have taken many strong antibiotics. Never again. I hope this got the UTI but only forcing food to take med and have rarely left bed in two days. Finished yesterday and still tired, hoping it gets better soon. F 51 5 days
 4  UTI Upset stomach, body aches and feeling like I was coming down with something. Back ache, bright colored urine. I can't take Bactrim, so my doctor gave me this. It helped but I think I would ask for something different next time if possible. Take with Food. F 43 5 days
100 MG 2X D
 3  Uti showed up after stone surgery Bit concerned about taking it now after some of the comments, hopefully nothing too major happens!! F 43 7 days
 1  UTI High fevers, chills, beet red face, whites of my eyes red as if blood vessels burst, second day vomiting, even cold water I drank came right back up and I'm a person who NEVER vomits, not even with both my babies and morning sickness. My head felt like it was going to explode and my daughter and I didn't put it together that it was a reaction to this horrible medication. I will list it as an allergy from now on. I'd recommend that no one ever take it.Too many choices out there than to risk the slight chance you'd have to go through days of feeling like you're really dying. I laid here for a few days because I couldn't even stand up, and I thought I'm going to die and my children are going to have to watch. It was probably the worst sickness I've ever had. DO NOT EVER TAKE. YOU HAVE WAY TOO MANY CHOICES THAN TO RISK GOING THROUGH WHAT I AND MANY OTHERS WENT THROUGH. F 56 3 days
 5  30 years of UTI's Liver function slightly impaired I have been taking macrodantin for 18 years after 30 years of UTI's. It saved my life. I have not had an infection since starting. My dosage has been reduced to 50mg after taking 100mg per day for over 15 years to help with my liver discrepency. Liver test back to normal now. F 53 10 years
 1  Bladder infection Exhaustion, nausea, muscle ache, loss of appetite, disorientation and poor sleep. Use with caution M 50 5 days
100mg x t
 4  uti none worked within 3 hours to abate excruciating pain of the UTI. F 39 2 days
1X D
 1  Bladder infection I was prescribed this drug by my urologist back in the early 1980's. After taking two doses, became severely ill with flu-like symptoms. Vomiting for five days, body aches, 102 fever, tremors, weakness, diarrhea and headache. I have never bee so ill in my life. Had to crawl to the bathroom on hands and knees. I actually thought I was going to die from this drug. Macrodantin is a serious drug. Use with extreme caution. Avoid taking if possible. I do not recommend it. F 57 3 days
 1  bladder infection Extreme vomiting for 3 days and no appetite for 5 days So very sick and only took 2 tabs please be very careful with this tablet Have informed my G P so I will not be prescribed this again F 75 1 days
 1  bladder infection Extreme vomiting for 3 days and no appetite for 5 days So very sick and only took 2 tabs please be very careful with this tablet Have informed my G P so I will not be prescribed this again F 75 1 days
 3  Bladder infection Very achy especially my back and legs. Tired and no ambition at all.....flu like symptoms F 54 6 days
100 mg
 3  UTI Nausea and dizziness . It feels as if my head is spinning . Now I take it at night .it works very well.looking at my urine in the morning something is coming out . F 19 2 months
 1  uti Strangely foggy head. At work was toLd I was 'spaced out' and I felt unable to get in touch with reality, disorientated - not in a nice way! Very scary feeling. Only took two doses but the effect lasted five days. F 58 1 days
not sure
 1  for a uti 1 days
 5  clears infection within 48hrs Only a bit of coughing and some flue like symptoms runny nose It's a antibacterial antibiotic which only works in bladder and kidneys had ongoing infections leaving my left kidney damaged for 10 years due to lower back problems from L2 to S1 was histerical cause all tests did not reveal any problem my symptoms was treated iso fhe cause since I had my back surgery all my urinary and intestine problem was sorted, macrodantin was and still is my life saver always keep some in my handbag.usually nfections hit me when it holidays or over weekends when all outlets and dr,'s are closed F 49 10 days
50mg 2X D
 1  Urinary tract infection Permanent scarring of the lungs. Can only walk a few steps and then give out of breath. This lung disease is permanent and I am now on prednisone A friend if mine also has the same lung disease caused by this antibiotic. She is now permanently on oxygen for the rest of her life. F 80 2 years
 1  suspected urinary tract infection All that have been mentioned. Exhaustion, aching, nausea, tingling, cramps, head throbbing, hands swelling Dreadful medication to take. Exercise caution. Cannot recall exact dosage as only just found this forum but am still suffering since July 2013. Only took for 2 days F 60
2X D
 1  UTI Severe headache, hot and shivering, loss of appetite, stopped taking them after 5 doses Quite scary would not recommend taking it. F 72 1 days
50 4X D
 1  post kidney infection Chills and fever, headaches, elevated heart rate, muscular aches throughout body, extreme fatigue. Am a Personal Trainer & athlete but am exhausted by simple tasks like sweeping, showering, etc. F 51 2 months
1x at nigh

MACRODANTIN  (NITROFURANTOIN, MACROCRYSTALLINE):  This medication is used to treat or prevent certain urinary tract infections. This medication is an antibiotic that works by stopping the growth of bacteria. It will not work for viral infections (e.g., common cold, flu). Unnecessary use or overuse of any antibiotic can lead to its decreased effectiveness. Nitrofurantoin should not be used in children less than one month of age due to the risk of a certain blood problem (hemolytic anemia).   (Sources: U.S. Centers for Medicare Services, FDA)