IMURAN Reviews (AZATHIOPRINE)

Average Rating: 2.9 (526 Ratings)

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 IMMUNOMODULATORS ANTIMETABOLITES

 Type: Rx Drug

  

IMURAN  (AZATHIOPRINE):  Azathioprine is used to prevent organ rejection in people who have received a kidney transplant. It is usually taken along with other medications to allow your new kidney to function normally. Azathioprine is also used to treat rheumatoid arthritis. In this condition, the body's defense system (immune system) attacks healthy joints. Azathioprine belongs to a class of drugs known as immunosuppressants. It works by weakening the immune system to help your body accept the new kidney as if it were your own (in the case of an organ transplant) or to prevent further damage to your joints (in the case of rheumatoid arthritis). Talk to your doctor about the risks and benefits of azathioprine, especially when used in children and young adults.    (Sources: U.S. Centers for Medicare Services, FDA)

  

Results are sorted by Age oldest to youngest.

Key to Ratings: 1=LOW (I would not recommend taking this medicine.)
5=HIGH (this medicine cured me or helped me a great deal.)

Page: 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27


RATING  REASONSIDE EFFECTS FOR IMURANCOMMENTSSEXAGEDURATION/
DOSAGE
DATE ADDED
 
 2  UC Tired, listless ,dizziness, diahrea, explosive BMs, hair loss, loss of electrolytes, pain in lower body muscles, swelling of feet, itching of lower body. Suspect allergy to the med. At 81 myself, this was a strenuos treatment. Would not recommend it for the frail or elderly. It stopped the UC bleeding after first three weeks of treatment, though. My Dr. wanted me to stay on it, but 'side effects' were too disabling. M 81
100 1X day
2/14/2013
 1  UC My father took this medication for 3 years and was diagnosed with a rare skin cancer. (Merkel Cell). Please do not take this medication. His doctor did not monitor him very well on this drug because I have the medical reports that state that my father had the flu a lot. At one point he had pneumonia and the doctor never decreased the dose or stopped giving him this drug. We are taught to listen to our doctors but this drug took my father's life. I am learning through these blogs that my father has not been the only one. Please email me. Maybe we can still fight for our loved ones, if we all stick together. I was thinking of passing a law that would require patients to sign a consent form before taking this drug. The consent form would list the known benefits but all deaths that followed after taking this medication. I live in IL. Does anyone know how we can start such a law if we are all from different states? Will anyone stand behind me? Please email me. My father was 79 when he passed away but was given this medication at 73 and diagnosed at 76. Why did his doctor give this medication to an older patient? Why didn't the doctor stop when my father complained of a having the flu? Does anyone have the drug write up from the pharmacy from 2001? I do not think cancer was listed because my father was also suprised to learn he had cancer. M 79 3 years
8/28/2009
Email
 1  UC My father took this medication for 3 years and was diagnosed with a rare skin cancer. (Merkel Cell). Please do not take this medication. His doctor did not monitor him very well on this drug because I have the medical reports that state that my father had the flu a lot. At one point he had pneumonia and the doctor never decreased the dose or stopped giving him this drug. We are taught to listen to our doctors but this drug took my father's life. I am learning through these blogs that my father has not been the only one. Please email me. Maybe we can still fight for our loved ones, if we all stick together. I was thinking of passing a law that would require patients to sign a consent form before taking this drug. The consent form would list the known benefits but all deaths that followed after taking this medication. I live in IL. Does anyone know how we can start such a law if we are all from different states? Will anyone stand behind me? Please email me. My father was 79 when he passed away but was given this medication at 73 and diagnosed at 76. Why did his doctor give this medication to an older patient? Why didn't the doctor stop when my father complained of a having the flu? Does anyone have the drug write up from the pharmacy from 2001? I do not think cancer was listed because my father was also surprised to learn he had cancer. M 79 3 years
8/28/2009
Email
 1  UC My father took this medication for 3 years and was diagnosed with a rare skin cancer. (Merkel Cell). Please do not take this medication. His doctor did not monitor him very well on this drug because I have the medical reports that state that my father had the flu a lot. At one point he had pneumonia and the doctor never decreased the dose or stopped giving him this drug. We are taught to listen to our doctors but this drug took my father's life. I am learning through these blogs that my father has not been the only one. Please email me. Maybe we can still fight for our loved ones, if we all stick together. I was thinking of passing a law that would require patients to sign a consent form before taking this drug. The consent form would list the known benefits but all deaths that followed after taking this medication. I live in IL. Does anyone know how we can start such a law if we are all from different states? Will anyone stand behind me? Please email me. My father was 79 when he passed away but was given this medication at 73 and diagnosed at 76. Why did his doctor give this medication to an older patient? Why didn't the doctor stop when my father complained of a having the flu? Does anyone have the drug write up from the pharmacy from 2001? I do not think cancer was listed because my father was also surprised to learn he had cancer. M 79 3 years
8/28/2009
Email
 5  autoimmune hepatitis I have been on azathioprine for 3 yrs with virtually no side effects. After being diagnosed (Oct. 2004) was put on Prednisone and azahioprine. After 18 mos. went in remission and off medication for 2 months and then had relapse. Back on prednisone and doubled the azathioprine (100 mg daily). Liver numbers normal in March 2007. Off prednisone, still in remission and hopefully off azathioprine in October, 2007. F 77 3 years
9/13/2007
 3  OCULAR CICATRICIAL PEMPHIGOID AUTO IMMUNE INCURABLE DISEASE OF THE EYE AFFECTING THE EYELID. TAKING IMURAN TO TRY TO HALT PROGRESSION. EXTREMELY FATIGUED, JOINT PAIN. RECENT INCREASE FROM 3 PER DAY TO 4 PER DAY TO SEE WHAT THAT DOSAGE CAN DO. THE DISEASE ATTACKS THE MEMBRANE AREAS OF THE BODY (AT ANY LOCATION) AND FOR THE EYE, IF NOT STABLIZED, CAN CAUSE THE EYEBALL TO BECOME FIXED IN PLACE, AS WELL AS THE LIDS TO TURN INWARD. THE DISEASE HAS ALSO AFFECTED MY MOUTH. IT IS CALLED AN EPITHELIAL SPLITTING DISEASE. F 77 8 months
50 MG 4X day
5/29/2011
Email
 1  Lambert Eaton Syndrome back pain, flulike symtoms, severe chills, and shaking, fever, headaches, mouth and tonsil sore, rash, itching, diarrhea Off Imuran for 36 hours now and still itching badly and diarrhea. F 76 3 weeks
12/14/2007
 2  Rheumatoid Arthritis Elevated Liver enzymes after two weeks. Did not work for me at all. Chinese Thunder God Vine Root[Lei Gong Teng] gave some relief. Now trying Enbrel[first shot yesterday]. M 74 15 days
7/27/2005
 2  Rheum Arthritis Stomach pain, elevated amylase liver enzime. [Dr. told me Pancreatitis] and no effect on RA after low to moderate dose for two weeks. Got a good price on the internet. M 74 14 days
2/15/2005
 4  auto immune hepatitis Tiredness mid to late morning. now swollen feet. Was on prednisolone but now ceased. Low resistance to infections - had tooth abscess, plantar wart and bruising on arms and legs. Red spots spontaneously appearing on arms and legs. Wounds take a long time to heal, I still have scars from skin lesions 3 months ago. Think it has helped my enzyme count so can't really complain. F 72 9 months
50 and 75 1X day
12/25/2015
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 2  crohns disease extreme muscle and joint aches and tremors and shaking at night. Starts about 4 hours after i take it and lasts about 45 minutes. Also sides of my head hurt. F 72 12 days
50 1X day
9/1/2022
Email
 2  Bullous Pemphigoid No side effects for the first two weeks. Then started having heartburn, gastric discomfort - moderate and constant, and nausea. The Dr. made me stop it for a week, symptoms went away 95%, restarted at 50 mg.daily. Symptoms returned in 48 hours. In addition I was having frequent labwork and my ALT and AST counts were going up. The second go round I was only on it for 6 days and the Dr. said to stop taking it. All gastric symptoms abated within 1 week. He made me see a gastroenterologist who recommended that I not take Imuran again. It was really helping me taper down on Prednisone (on Pred. for 1 1/2 years) but he said it was causing some liver toxicity and possible mild pancreatitis. I live for the day I can come off the Pred. but in my case Imuran is not worth the other risks. F 72 5 weeks
100 mg. 1X day
5/24/2010
 1  Pulmonary Fribrosis/Dermatomyositis Stage IVB Squamous Cell Carcinoma Deceased in 8 months M 71 4 months
1X day
1/30/2017
Email
 5  Autoimmune Hepatitis Hair loss,weight gain and in the morning or after sitting for a long time (2 hours) my feet and ankles are stiff. I have been on this drug twice before but it was 25mg. With Allopurinol. That worked great with no side effects except it could could cause bone loss. Was taken off but had a flare up so new Dr put me on just Imuran. Working great. I don't like the side effects but I would rather be bald and fat than dead. F 70 9 months
50 mg
1/4/2020
Email
 1  autoimmune nephrithis severe leg muscle cramps, bad swelling lower extremities. changes in skin.. moles.. new dark spots on face and body.. just feel bad most of time. F 70 2 months
50 mg 1X day
9/29/2013
 1  Oral Licen Planus. After about 30 days developed a horrible gastritis where I could hold nothing down and vomited all day. It took me a while to twig what was causing this. Also my libido (such as it is) just vanished. I would never take this drug again. I would prefer to put up with oral lichen planus. M 70 30 days
50mg 1X day
4/27/2012
Email
 1  myasthenia gravis Septicemia, when bacteria get into your bloodstream. It is fast acting and hard to diagnose and has a mortality rate as high as 50% and patients can have impaired reason so might not know they are that sick. You basically go into toxic shock and have organ failure. It might be too advanced to cure if you wait for a lab result as it progresses rapidly within days and seems ot escalate fast in the last 24 hours. Different viruses have a variation of morbidity rates. He got 2 different cases of Septicemia. They cured the first one and a more aggressive germ got him a few days after he was taken off life support and within a few days he went into shock and had a heart attack. My father took Imuran for 1 week and on his follow-up appointment (7 days later) he had a fever of 101. He was getting sick and the doctor gave him a prescription and told him that he could fill it in the evening if he needed it. When my mom took him to the hospital's emergency room that evening with a fever of almost 104 and chills, the doctors sent him home with aspirin and an antibiotic, which he may or may not have taken as he was very ill. He seemed to get better and we thought he was taking his medicine but he almost died that Friday as he started going into toxic shock and his Kidneys started to fail, it takes 2-3 days to get lab results. After being on life support his septicemia was cured and he was ok for half a week when a new infection progressed into his blood stream and caused a new case of septicemia, this one he caught at the hospital so it was resistant to many different antibiotics. We are now arranging his funeral. My father was on a different medicine IGG previo M 69 7 days
7/7/2007
 1  Autoimmune haemolytic anaemia Fatigue, jaundice, Hair thinning (no loss yet), Interstitial pulmonary infection, Excessive sweating My mother has been on Imuran for about 2 months and so far has been hospitalised for a severe pulmonary infection. She is 69 and the doctor that was called out to see her at home seriously didn't think she'd make it. She is tired all the time and suffers with yellow jaundiced eyes. She hasn't lost any hair yet but it's thinning and only time will tell I guess. My mother is a get-up-and-go woman who cannot sit still but since she has been on Imuran she has lost her zest for life and I am very worried - I have never seen her like this before. We are at present compiling reserach on alternative treatments. F 69 2 months
8/2/2008
 5  Lupus I started out at 50mg once a day for 4 months, but fluid began building up around my heart again. So doctor increased to 75 for a month and finally to my maintenance dose of 100mg a day. It takes about 3 months for this drug to take full effect. I place the pills in gel capsules to prevent stomach upset and also take it with a meal. I have IBS and have had no stomach upset at all from Imuran. I can't think of any side effects I have had from it. I am really doing much better...except for periodic bouts of fatigue. I am back to exercising most days....less muscle pain. Imuran does not help with Lupus fatigue at all, but I am relieved to have no more organ involvement. So far the periodic blood checks have shown no problem with liver function due to Imuran. Once I have been on my maintenance does for one year, the doctor wants to begin reducing the dose and see if I can go without it for a while. I am glad this one works for me as I had a very bad allergic reaction to Plaquenal...covered in hives. Everyone is different so don't let the negative comments steer you away. I am just glad there is something to treat this illness. Wish there were more options available though. For me.....so far, so good....for now. 68 1 years
100 mg 1X day
3/23/2016
Email
 2  Interstitial Pneumonia Pulmonary Nausea/heaves/sinus drainage/mouth sores/sore throat/hoarseness/week body/very week and extremely painful legs 1st week started at 50mg just felt nervous and had shakes inside and out,, 2nd week at 100mg I got a terrible cold extreme head drainage and sweating constantly. Then when I start the 3rd week at 150mg is when the worst came about. Vomiting with extreme heaves, loose bowels, and weakness. Dr. cut me back to 100mg. Tried that side effects still the same. Dr. cut me back to 50mg daily. One week later I wake up to use the bathroom and could barely walk. Urinating has become painful. Husband got me the walker. Had that from a previous surgery. Trying to stand was very painful and very difficult. I had a fever of 100.2 which lasted all day. I got the chills often shaking terribly. In other words this med is playing havoc with me. I'm afraid to start it again. F 68 21 days
50mg -150m 1X day
2/11/2019
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IMURAN  (AZATHIOPRINE):  Azathioprine is used to prevent organ rejection in people who have received a kidney transplant. It is usually taken along with other medications to allow your new kidney to function normally. Azathioprine is also used to treat rheumatoid arthritis. In this condition, the body's defense system (immune system) attacks healthy joints. Azathioprine belongs to a class of drugs known as immunosuppressants. It works by weakening the immune system to help your body accept the new kidney as if it were your own (in the case of an organ transplant) or to prevent further damage to your joints (in the case of rheumatoid arthritis). Talk to your doctor about the risks and benefits of azathioprine, especially when used in children and young adults.    (Sources: U.S. Centers for Medicare Services, FDA)

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