IMURAN Reviews (AZATHIOPRINE)

Average Rating: 2.9 (526 Ratings)

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 IMMUNOMODULATORS ANTIMETABOLITES

 Type: Rx Drug

  

IMURAN  (AZATHIOPRINE):  Azathioprine is used to prevent organ rejection in people who have received a kidney transplant. It is usually taken along with other medications to allow your new kidney to function normally. Azathioprine is also used to treat rheumatoid arthritis. In this condition, the body's defense system (immune system) attacks healthy joints. Azathioprine belongs to a class of drugs known as immunosuppressants. It works by weakening the immune system to help your body accept the new kidney as if it were your own (in the case of an organ transplant) or to prevent further damage to your joints (in the case of rheumatoid arthritis). Talk to your doctor about the risks and benefits of azathioprine, especially when used in children and young adults.    (Sources: U.S. Centers for Medicare Services, FDA)

  

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Key to Ratings: 1=LOW (I would not recommend taking this medicine.)
5=HIGH (this medicine cured me or helped me a great deal.)

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RATING  REASONSIDE EFFECTS FOR IMURANCOMMENTSSEXAGEDURATION/
DOSAGE
DATE ADDED
 
 4  autoimmune liver disease F 16 11 months
1.5 1X day
4/24/2011
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Patient History
 1  Uveitis No energy, loss of appetite, baseball sized tumor in side, inability to focus, malaise,muscle aches, nausea, lower back pain. Lost 30 pounds in less than 1 month. I used to think the eye injections were bad until I started immunosuppressant therapy. 3 months ago I stopped taking it, then had a baseball sized tumor removed from my side. This thing had tentacles. Now it has grown back. The tentacles wrapped around the nerves that travel down my right leg. Back is hurting and I can barely walk. I told the doc about the side effects and all he cared about were liver function tests. Be very careful with this dangerous drug. Maybe it should be marketed as a weight loss drug-if only it weren't so nasty. F 54 2 years
50 mg 3X day
4/2/2011
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 2  UC Fattigue, muscle aches, dont want to do ANYTHING So my new doc. put me on this per my request (i want to get off P-zone been on it off an on for 20 years HATE IT)wanted to try something else. super fatiged from the start, i had read this thread before i started the meds and we talked about the fatige and he assured me it doesent, wrong so my next visit i printed it and tried to show him it, wow wrong thing to do he was rather upset and super defencive about it,it something else no one on there knows what they are taking about i have 100s of people on it and it cant cause that, on and on. more blood tests and if they come back negitive then i am going to stop taking it for a week or so to see if i feel better. M 49 2 months
100 1X day
3/2/2011
 4  UC fatigue, joint and muscle aches, harder to loose weight been on Imuran 3 months now, UC is considerably better,the best it's been in a year. I have some fatigue but it has gotten better since staring drug, harder to loose weight that I gained on prednisone. I work in a lab so I check blood levels weekly, all is well so far. So far the good out weighs the bad, hoping for continued success on drug. Going to FL in a couple of weeks hoping sun sensitivity wont be a problem. Have been worried about some of the side effects I've read about but so far have been minimal. F 41 3 months
100 mg 1X day
2/28/2011
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 2  Psoriatic Arthritis Extreme fatigue, rash, shortness of breath, headaches, loss of appetite, nausea, and many increased infections (fever of 104 3x when taking Imuran). Also got a chronic ear infection that did not resolve until I was off the medication for 2 weeks. This drug improved my symptoms only minimally, if at all, and since I only had mild psoriatic arthritis in the first place I decided it was not worth the side effects and the risk. M 39 3.5 months
50-100 mg 1X day
2/3/2011
 4  Crohn's None that I can definitively link to Imuran. I am finding it more difficult to concentrate and focus on things, as if my brain is scattering everywhere at once. I've been intelligent and quite able for mental gymnastics my entire life, so it's a bit disconcerting. Has anyone else experienced anything like this with Imuran? M 51 8 years
100 1X day
1/15/2011
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 5  UC Bloating, moon-face, but attribute these to Prednisone. Also tired more often than before imuran. Tried every med available, only prednisone improved UC. Last flare resulted in hospital for 12 days. Prednisone / Asacol no longer providing relief. Started Imuran / Prednisone / Asacol and in remission for 4 weeks now. Starting to ween Prednisone, hoping Imuran / Asacol will maintain remission. So far very happy with Imuran! M 47 17 weeks
50mg 2X day
12/29/2010
 2  Ulcerative Colitis Major hair loss on head, yet hair growing everywhere else; tiredness; soreness; joint problems; tender breasts; blurred vision; increased warts and acne; upset stomach; moodiness; swollen everything; major gynecological problems. At first, the benefits outweighed the side effects. Now I'm not so sure. I'm a teacher and I always have to be on alert, but I can't stand on my feet past 9:00 a.m., I'm constantly in a bad mood due to my pain which increases during the day; I've been to ERs and clinics due to my swelling; and now I've been to 3 ob-gyns for gynecological problems. Yet my doctor doesn't seem too concerned with these side effects. He thinks as long as my colon is in good health the rest shouldn't matter. And I don't understand how my hair can be falling out of my head yet growing so quickly everywhere else. F 31 6 months
100mg 1X day
12/21/2010
 1  a misdiagnosis Hair loss, yellow skin, warts, weak immune system, infections, acne University of Iowa = crappy school, worse hospital, horrible doctors. M 18
100 1X day
12/1/2010
 2  ILD Interstitial lung Desease losing energy now on O2 when do the littlest exersion fatigued. can not sleep well head aches on prednisone as well seems not to help down to 10 mg a day M 43 4 months
200 1X day
11/29/2010
 1  immune disorder Big warts on face, hair loss, yellow skin. F 18
1X day
11/27/2010
 1  Misdiagnosed UC Hair loss, acne, warts, skin growths all over face M 35
1X day
11/13/2010
 4  non specific auto immune disease fatigue I have been taking it along with 200mg of Plaquinel for about 2 years now. I have noticed a significant change in my life since being on it. Occasionally I experience severe fatigue, but my flair ups have been less frequent and less severe since it "kicked in" so I feel it's occasionally worth it. It took 2 months for it to reach full effect for me so I encourage people to give it time to make a difference. F 29 2 years
100mg 1X day
10/9/2010
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 5  crohns disease minimal hair loss, abdominal rash continuos-mild-,achy joints (may not be related) It worked great the first time i tried it then of course i stopped it after two years got sick again then restarted drug took about 3 months to balance out now going great for 6 years F 51 6 years
50 mg 1X day
10/2/2010
 5  UC joint pain, tired Imuran has been the only drug to help UC. I had allergic reactions to all other meds previously prescribed. started on 100 mg per day and have increased 200 mg in the last 3 months. No hair loss. UC is under control. will deal with Imuran side effects vs. 10-12 trips to the restroom per day. F 35 6 months
200 MG 1X day
9/28/2010
 5  autoimmune pancreatitis Significant joint pain, muscle ache, fatigue for initial 3-4 months. Some hair loss but improved after 6 mths. After several failed runs of prednisone (which is usually successful with AIP) starting as high as 60 mg, I began Imuran at 100 mg. Haven't had any further AIP flare-ups whatsoever (knock on wood..) LFTs are excellent, feeling generally ok. Haven't experienced any sun sensitivity but have been cautious in that regard. F 54 11 months
100 mg 1X day
9/13/2010
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 4  Auto immune hepatitis Slight hair loss but better texture than on pred. More fatigued now on imuran alone but think it could be now I'm not taking pred which gave 'false' energy. A little fluid retention & struggling to lose the weight I put on originally on pred. Extreme reaction to sun though - need constant shade & spf50 otherwise skin almost blisters & I get flu-like symptoms - not great!! Might rethink summer holiday plans now... Iceland maybe?? When diagnosed in March lft showed ast levels of 1300+, initially 50mg pred/day which brought it under control, but ended up manic & eating like a horse! Plus insomnia! Prescribed imuran alongside but have weaned off the pred & have been pred-free for about a month now - phew! Feel better for it other than feeling a bit more tired. Don't like not being able to be in the sun (even sunscreen isn't sufficient) but would rather be alive! Not medicating me is not an option or my liver would fail. Levels now regularly 16-19.... thanks imuran! (Wee a bit fluoresent tho....but not brown any more - hurrah!) F 46 7 months
100mg 1X day
9/2/2010
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 4  Crohn's Disease Nausea, fatigue, headache, nose bleeds, sun sensitivity, inability to sleep, lack of appetite Most of the side effects with Imuran have dissipated over the years and it has become something I must take to keep my Crohn's flare ups under control. M 31 10 years
50 MG 3X day
8/30/2010
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 3  ulcerative colitis Extreme tiredness, muscle pains and weakness caused by vitamin D deficency, acne, skin rashes, excessive sweating and body odour, sore eyes, sinus problems, nightmares, night sweats, I've been on this for just over two years now. Have changed my consultant due to a residential move and have been told that I have been on the drug too long and that I should now come off of it! From what I have read, it is normal, if the drug can be tolerated, to be on it for some years! I have agreed to cut the dose and come off of it as I have just about had enough with the tiredness, muscle pains and weakness. My vitamin D levels have been so low that I'm having to have regular vitamind D injections. Ok, I haven't had to go looking for toilets all the time over the past 2 - 3 years, but my quality of life has been a big zero. I have had no social life as I am just too tired to do anything, even more so than when my UC was at it's worst. I have a had an itchy rash on my right arm and on my face, along with acne, since I started the drug and nothing I have used or been prescribed has helped - even dermatologists have drawn a blank. Weighing up the pros and cons, I am happy to stop it. Just to say that I live in the United Kingdom (England). F 45 700 days
150mg 1X day
8/30/2010
 5  Crohn's disese None Imuran has enabled me to taper cortisone (Prednisone) down to 1.5mg/day and I'm hoping to be able to go off Prednisone completely within a few weeks. It has allowed me to live a normal life - including a three week trip into the desert where there was no possibility of medical help. My Crohn's is in the "Mild to Moderate" range. M 59 8 months
200mg 1X day
8/27/2010

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