IMURAN Reviews (AZATHIOPRINE)

Average Rating: 2.9 (526 Ratings)

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 IMMUNOMODULATORS ANTIMETABOLITES

 Type: Rx Drug

  

IMURAN  (AZATHIOPRINE):  Azathioprine is used to prevent organ rejection in people who have received a kidney transplant. It is usually taken along with other medications to allow your new kidney to function normally. Azathioprine is also used to treat rheumatoid arthritis. In this condition, the body's defense system (immune system) attacks healthy joints. Azathioprine belongs to a class of drugs known as immunosuppressants. It works by weakening the immune system to help your body accept the new kidney as if it were your own (in the case of an organ transplant) or to prevent further damage to your joints (in the case of rheumatoid arthritis). Talk to your doctor about the risks and benefits of azathioprine, especially when used in children and young adults.    (Sources: U.S. Centers for Medicare Services, FDA)

  

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Key to Ratings: 1=LOW (I would not recommend taking this medicine.)
5=HIGH (this medicine cured me or helped me a great deal.)

Page: 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27


RATING  REASONSIDE EFFECTS FOR IMURANCOMMENTSSEXAGEDURATION/
DOSAGE
DATE ADDED
 
 4  Autoimmune hepatitis Head aches, hair loss, back aches, abdominal pain, really tired all the time & nauseous feeling. As crappy as the side effects are, this medication has helped me with controlling my Autoimmune Hepatitis. F 45 9 months
75mg 1X day
10/21/2012
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 1  NSIP Liver enzymes went through the roof. Retried to take it a few months later and 2 days into the treatment was in severe pain. Liver enzymes escalated. My doctor said I was deathly allergic to it. F 59 4 months
50 MG 2X day
9/1/2012
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 4  Myasthenia Gravis Deep joint, bone & muscle pain since going off Prednisone which was taken simultaneously until 4 months ago. Have had MG for over 40 years, and immunosuppressant therapy stopped progression and put MG in remission--success! The cost from Pred has been great bone loss, multiple fractures and now only on Imuran--going to stop this soon as well and pray MG stays in remssion. F 53 3 years
50 mg 3X day
8/20/2012
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 3  Re occurring "Stevens Johnsons" Easy bruising of the skin , nausea , weight gain pain in knees and wrist and very hard to unwind and sleep . My child is 11 years old . And unfortunatly suffers from re occuring "Stevens Johnston syndrome" from the age of 6 , My husband and i were very anxious about him starting this drug *hence* the severe side effects !! He is currently in re mission but with above side fx M 11 18 months
100mg 1X day
8/16/2012
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 1  Crohns Disease Where do i start......bleeding gums,headaches, nausea, loss of appetite, mouth ulcers, affected my sight and sight perception (like i was halusinating), dermititis an my face, fatigue, confusion and being very vague, thrush and flu due to low immunity and servere chest pain. Plus all the side affects from the prednisone I am a single mother of 2 children 5yrs & 3yrs. I have had Crohns for 26yrs. Before children I had time to use alternative medicine to heal my illness. I do not have time now to meditate, relax & give herbal medicine time to work. So I have had to succumb to my Drs wished and take the stupid drugs (I thought as a quick fix, boy was I wrong). NEVER AGAIN! The side affects of the prednisone and imuran are far worse than the symptoms of Crohns. This weekend I thought I had 3 heart attacks. The pain in my chest was that bad I nearly called an ambulance. That was the last straw. I went back to my specialist and she told me to stop the imuran as she had only ever had 1 other patient that complained of this too. I had constant chest pain for 4days I stopped taking the imuran yesterday and the pain has gone. I am nearly off the prednisone now too. Back to natural medicine I go. It has done more for me than this other crap!. Acupuncture, chinese and herbal medicine deals with Crohns Diesease in a much more humane manner. I am happy to communicate with fellow Crohns sufferers also. I wish you all love and strength x F 41 8 weeks
75mg 1X day
8/13/2012
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 2  Auto Immune Hepatitia ocassional headaches, joint pain, diminished appetite, lack of energy, skin discoloration, diarrhea,some things taste funny (ie watermellon). I started Imuran 6 months ago and weaned off prednisone. Although I got very puffy with prednisone, I felt much better than I do now. My doctor just upped my Imuran two days ago to 175mg.because although my ast and alt we good(28/23) my liver was very swollen. I am not surprised since I had complained that my liver hurt for the past 6 weeks ever since my prednisone was lowered from 10mg. to 5mg. I have actually lost about 3 pounds since starting Imuran and was lucky enough not to have gained any on prednisone. I am hoping that as time goes on I can change my rating to a higher number. F 63 6 months
175mg 1X day
8/8/2012
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 1  Ulcerative colitis I was put on Imuran to regulate my flare ups. At the time I was also on prednisone. As soon as I stopped the prednisone I started throwing up and had extreme fatigue. I also had stomach pain and elevated liver enzymes. I chose to stop the med on my own because I thought I was having an allergic reaction to it. After a week off my doctor wanted me to restart to see if that is what was happening. within an hour of taking the first dose back on I became violently ill. I was throwing up and had really bad diarrhea. i felt so sick that I actually though I was going to die. I will never take this medication again. F 32 2 weeks
25mg 1X day
7/25/2012
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 2  Lupus Extreme sensitivity to light and sun burning within minutes, muscle weakness, unexplained dizziness, burning eyes, vision changes Lupus diagnosis in January 2012. Over last 7 months on 60mg Prednisone and now tapering...currently 35mg Prednisone and 150mg Imuran...now liver enzymes rising and slightly anemic again...over all feel worse than without any medications if that is possible. Lupus tests still show inflammation levels high even on 150 mg of Imuran so I am not sure that benefits are even established yet but side effects and stress to other body systems are starting.... F 53 90 days
150 MG 1X day
7/21/2012
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 2  Lupus I am having some headaches, stomach upset, nausea, tired all the time, and loosing a lot of hair. F 36 2 weeks
50 mg
7/14/2012
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 1  UC This drug is terrible. While taking it, i developed sinus infections every couple months. I also would go through episodes where I would get very light-headed, dizzy, become extremely pale, sometimes would faint, severe debilitating migraines, jaw tension, sensitity to light, moderate acne. Since I got myself off this drug, all those symtops except the jaw tension and severe migraines, ceased. The migraines I believe are a result of the other drugs I have to take for UC, namely asacol. When I have a flare up, I am prescribed predinsone, which makes those symtops worse, and the prednisone has had a diminisioning effect over time, as that happens with a steroids. My best advice is to have a serious talk with your M.D. and do not let them intimidate you with medical talk. The majority of M.D.'s, only know how to throw drugs at a problem, and will do so because that is where they get their funding. Explain to your doctor they cannot hide behind drugs anymore, and that they need to address these issuses with logic, reason, and COMPASSION. I have fired my GI, and am now under the care of another, that is working with me to get me off, and keep me off the meds. In conclusion, STAY AWAY FROM PREDNISONE, IMURAN, ASACOL, and all the other chemicals the medical industry will throw at you, and find a REAL doctor. M 26 3 years
30mg daily
6/24/2012
 5  Crohn's Isease Slight fatigue in the beginning, but grew used to it and just ended up going to bed a bit earlier. As the summer months came, I noticed that my skin was very prone to sun burns (which it wasn't before using imuran). The drug has kept my Crohn's in remission, so it is doing it's job. M 26 5 months
150MG 1X day
6/20/2012
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 1  Auto immune hepatitis After 2 weeks, severe nausea & diarrhea 1 to 2 hrs aftet taking. Tried to tolerate for 2 more weeks but nausea got worse daily.Tingling feet & hands. Changes in taste&smell. Pale colored stool. Weakness & fatigue. Stopped taking after 35 days on it. F 57 1 months
50 mg
5/28/2012
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 2  Myasthenia Gravis Fatigue and weakness are worse, exhausted most of the time, sun sensitivity with short exposure, mild stomach upset I'm waiting to see if this will kick in to make the MG better - supposed to take 3-12 months. But these two weeks have been difficult. F 37 2 weeks
50 mg 1X day
5/16/2012
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 1  Oral Licen Planus. After about 30 days developed a horrible gastritis where I could hold nothing down and vomited all day. It took me a while to twig what was causing this. Also my libido (such as it is) just vanished. I would never take this drug again. I would prefer to put up with oral lichen planus. M 70 30 days
50mg 1X day
4/27/2012
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 4  UC I have had UC for the last 23 years. The last 2 years, the maintaining agent I have been using stopped. The only way it is now under controll is working in conjuction with 800mg of Asacol daily. I am glad that mu UC is under control, but now I am developing fatigue, and acne on my face. My whole body feels bruised also. I am also beginning to feel the itchiness on my upper arms. I don't know if these symptoms are going to get worse, and the long term side effects really scare me. I can't wait for the time that I can get off of this drug. F 43 1 years
150mg 1X day
4/4/2012
 4  Auto Immune Hepatitis Sensitive to sun. I get burnt very easily but wearing a hat and sunscreen seems to correct it. I also have no appetite. But if I don't eat, I get sick and the thought of food makes me sick. The worst is joint and muscle pain. It is random (i.e. one day it affects all the joints in my fingers, the next it is my knees, the next day...all the joints in my feet). The severity of the joint & muscle pain has decreased slightly since I have lost a little weight. I used to take Prednisone, which worked very well. I didn't like the side effects coming off the Pred., but am glad I was able to take it to control my liver function numbers. I don't enjoy taking Azathioprene(Imuran) but I am grateful for it. It has kept me alive so I can be around for my little ones. F 37 2 years
100 MG 1X day
3/25/2012
 1  Ulcerative Colitis In ONLY five weeks time, these are the side effects that I have: Memory loss, fatigue/listlessness, sinus infections, icepick headaches by right ear, dry skin on forehead, and the topper; Herpes Simplex virus outbreak (tender bumps, clusters) on my neck and back of head/scalp confirmed by my dermatologist. My gastroenterologist told me to stop taking it. Gee, I wonder why??? I'm a 58 yr. old male and I wouldn't recommend this drug to anyone, period. It has SO MANY bad side effects and many I'm sure that we're not aware of yet. The fact that it might cause cancer down the road is enough to stay away from it. WAY TOO DANGEROUS for the rest of your body when trying to cure one thing. Run from this drug as fast as you can!!! M 58 5 weeks
50mg 1X day
3/1/2012
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 5  vasculitis none F 26 3 months
50 mg 2X day
2/3/2012
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 1  Chrons Strong warning not to take this medicine!!!!! This caused a death in my family of a woman in good health - only 3 weeks after being prescribed it, and it caused "Sepsis" which is blood poisoning due to infection which is a result of the immune suppressing properties of the Imuran. BEWARE !!!!!!!!!!!!!! BAD BAD BAD BAD BAD F 63 22 days
n/a 1X day
2/1/2012
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 1  Chrons I took Imuran for 18 months without any problems. Then it started to decrease my immune system to the point that it was so bad, I was like a cancer patient on treatment. I got sick with a respiratory virus and respiratory bacteria. I was admitted to the hospital and within 2 days, I had been intubated and was on a ventilator to help me breath. I was in a medicated coma for 14 days. I had interstitial pneumonitis due to toxicity of the Imuran in my lungs, which allowed the diseases to take over. My lungs were not the only things affected. My liver shut down, as well as my kidneys (did dialysis for 5 weeks), and my intestines too. The doctors said I had a 70% chance of dying, but thankfully for my family and friends who prayed over me EVERY SINGLE DAY, I am now home and recovering!!! I am only 32, and if this had happened to someone older, they may not have survived! People need to understand that Imuran can literally kill you by wiping out your immune system if you're not care I think the poster who said that there should be a Consent needed before taking this drug was smart! I like the idea! M 32 18 months
50mg 3X day
1/28/2012

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