IMURAN Reviews (AZATHIOPRINE)

Average Rating: 2.9 (526 Ratings)

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 IMMUNOMODULATORS ANTIMETABOLITES

 Type: Rx Drug

  

IMURAN  (AZATHIOPRINE):  Azathioprine is used to prevent organ rejection in people who have received a kidney transplant. It is usually taken along with other medications to allow your new kidney to function normally. Azathioprine is also used to treat rheumatoid arthritis. In this condition, the body's defense system (immune system) attacks healthy joints. Azathioprine belongs to a class of drugs known as immunosuppressants. It works by weakening the immune system to help your body accept the new kidney as if it were your own (in the case of an organ transplant) or to prevent further damage to your joints (in the case of rheumatoid arthritis). Talk to your doctor about the risks and benefits of azathioprine, especially when used in children and young adults.    (Sources: U.S. Centers for Medicare Services, FDA)

  

Results are sorted by Date added.

Key to Ratings: 1=LOW (I would not recommend taking this medicine.)
5=HIGH (this medicine cured me or helped me a great deal.)

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RATING  REASONSIDE EFFECTS FOR IMURANCOMMENTSSEXAGEDURATION/
DOSAGE
DATE ADDED
 
 3  RA and ILD vomiting flu like F 54 2 months
100mg
8/27/2014
 1  Myositis Dizziness, severe muscle spasms, stomach pain, lightheadedness. I started taking Imuran because Prednisone wasn't controlling the release of muscle enzymes. Soon after starting Imuran, I had a 103 fever for three days which developed after being in a cold room for 2 hours. After feeling generally lousy for three weeks, I realized the Imuran may be the cause. During that time, I hurt my back just from doing very light exercise and the pain never went away. For 4 weeks, I suffered from a severe back ache. Two days after stopping Imuran, the back ache got better, dizziness and all other symptoms disappeared. F 52 4 weeks
50 mg. 2X day
8/20/2014
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 3  Autoimmune hepatitis Extreme muscle weekends and pain in legs. Swelling and numbness in feet. Hip and severe lower back pain. Now using a cane. Praying my doctor will let me reduce mg F 67 2 years
75mg
8/8/2014
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 5  Wegeners Gran. Minimal side effects. Began at 50 MG per day and as prednisone was slowly decreased, IMURAN was increased. This drug is keeping me alive. F 63 1 years
150 MG
7/30/2014
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 2  Behcets disease Severe joint pain, headaches, muscular pain, severe perspiration all day. Had to increase pred to 40 a day to help with pain. F 57 10 days
100 mg
7/24/2014
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 5  Crohn's Disease Headaches, fatigue, itchy skin, skin growths and rashes,sun sensitivity, minimal hair loss, dizziness and joint pain. Despite side effects,I think this drug has saved my life. Prior to taking, had numerous ops including 2 perforated bowel and peritonitis episodes which were nearly fatal. Permanent ileostomy with some complications but quality of life so much better than before. Been on it for 16+ years and Will stay on it as long as my health allows. F 39 10 years
100 mg
4/24/2014
 3  crohns disease Fatigue constantly and now my kidneys have become inflamed and doc has stopped my azathioprine and good riddance to it , why is it affecting my kidneys ? Any ideas M 38 7 years
150 mg per
4/24/2014
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 2  Crohn's While Imuran kept my Crohn's disease in remission for many years, it has done tremendous damage to my liver. Only after vomiting blood did I find out that the Imuran had caused hepatoportal sclerosis, which caused enlarged varices in my esophagus and stomach. I have since had to have a surgical shunt procedure performed. I'm not sure what the outcome of this will be, but I'm not optimistic...... ASK QUESTIONS! Make yourself an informed patient by researching the side effects of Imuran. A live biopsy can be performed as an outpatient procedure, if you've been on this drug for any extended period of time, and your doctor notices any change in your liver enzymes, get one done. M 49 10 years
150 mg 1X day
4/14/2014
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 4  Colitis Initially I had no side effects, and Imuran has really helped to bring my colitis under control. It was starting to dominate my life. After 6 months on the tablets I began to experience joint pain in my fingers, knees and feet. This has got to the point that I am having significant difficulty walking, especially after sitting/ waking up. Xrays show no sign of arthritis. With reluctance I am now coming off the tablets. They have in my opinion helped me significantly. Great results with my Colitis, just the negatives started to out weigh the positives. F 43 1 years
100mg 1X day
4/5/2014
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 3  Autoimmune Hepatitis Moderate to severe (after physical exertion) joint and muscle pain. Knees, elbows, shoulders, fingers and spine affected the most. A throbbing deep bone pain in my legs if standing for any length of time. Thinning and coarser hair. Unable to sleep but I think that's because of the pain. Joints seize up if in one position for too long. Works wonderfully for keeping my AIH in remission. The side effects are disabling at times however. Was on steroids before and during the first 2 months of Imuran and I CAN NOT handle the side effects of prednisone. Will deal with pain any day over the freak show that is prednisone! F 37 4 months
75 mg 1X day
2/3/2014
 4  Crohns Nausea to being with which lasted quite a while without improving. Rather than give up on it the doctor prescribed lanzaprozole to suppress stomach acid and that has helped enormously and allows me to tolerate the imuran. Have had more colds and bugs than normal, and one particularly nasty throat infection but this is much better than having a crohns flare. Have recently started to get a lot of joint pain but not clear if this is due to Imuran or not and as long as bloods stay ok I wouldn't swap it for what went before. Hospitalised three times in the 12 months prior to starting but under control since. Very closely monitored with bloods test and good access to both my GP and GI so when there have been 'scares' along the way have always felt in control. M 31 18 months
150mg 1X day
1/6/2014
 5  kidney transplant - to avoid reject hot flashes in my 20's - gynae said it was the asathioprine, and it settled down. Keeps me alive, it does. Not many transplanted kidneys last as long as mine has. F 53 32 years
100mg 1X day
12/31/2013
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 1  auto immune disease fatigue and muscle ache F 43 1 weeks
100mg 1X day
12/6/2013
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 5  chrons my chrons was out of control until I started taking imuran,couldnt work or enjoy life.1st week of taking had to stop due to extreme fatigue, waited a couple of weeks tried again and no extreme side effects except for slight fatigue now and then.with in a month and abit of starting back on it went back to work fulltime and come leaps and bounds since, I dont even relise ive got chrons since the imuran M 4 months
100 1X day
11/26/2013
 5  autoimmune hepatitus possible sight issues just cut dose to 50mg per day and can actually work on computer and see keys with out glasses other than that this drug saved my life liver was shutting down and soon in big trouble now im 52 and all ok hope that I can get right off drug soon M 52 18 years
100 1X day
11/11/2013
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 5  Crohn's disease (12 years) Low WBC which resolved when dose was lowered. I am in complete remission with zero symptoms. I was able to come off prednisone and get my life back. I used it when I was younger too, but came off to get pregnant and have a child. The remission remained for a few years after I stopped that time. F 32 2 years
100 1X day
11/9/2013
 2  warm autoimmune hemolytic anemia acquired hemolytic anemia from what I believe was a side effect of other medications I was prescribed for a head injury. After 2 years of taking it I was experiencing sweats, joint muscle pain, very dark urine, jaundiced eyes, weakness, HGB 90, abdominal pain and I decided as a last resort I would quit taking it. almost immediately my urine started clearing , over the next month the sweating stopped and I felt cooler, the abdominal pain has almost completely subsided, the jaundice has almost gone. I feel a bit stronger. I will see what the next blood tests say but I am thinking I did the right thing . Everybody is different and though stopping seems to be working for me it may not for someone else. I should add that I have been extremely careful with my diet ; ie very little junk food, alcohol and eating lots of red meat, vegetables, dates, fish, etc. I have been taking supplements , walking... not sure if this info will be helpful to anyone else or not . my last HGB count was 97 (after 6 weeks)and I feel it is rising. The chaotic head injury symptoms remain as relentless as ever. M 55 2 years
100 1X day
10/27/2013
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 1  autoimmune nephrithis severe leg muscle cramps, bad swelling lower extremities. changes in skin.. moles.. new dark spots on face and body.. just feel bad most of time. F 70 2 months
50 mg 1X day
9/29/2013
 1  churg strauss, vasculitus and fibro horrific diahoreah and vomiting, could not walk or talk, kidneys failing, turned blue and had to be resuscitated in the high dependency unit, blood pressure nearly unreadable, SATS 80 percent and lowering if I could rate this poison minus 100 I would....this should be taken off the market before more ppl die or have near death experiences horrible stuff and im lucky to be here to be able to write this!!!! really think hard before taking this medication!!!! F 42 10 days
50 1X day
9/20/2013
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 3  Rheumatoid Arthritis, Pericarditis Occasional, mild acid reflux I believe that Imuran is the reason I can get my prednisone dose down to a minimal maintenance dose. It took a few weeks to take effect, and the effect was not dramatic for me. I just know I'm at the lowest dose of prednisone I've been on for over a year. F 50 5 months
150 mg 2X day
9/9/2013

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