IMURAN Reviews (AZATHIOPRINE)

Average Rating: 2.9 (526 Ratings)

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 IMMUNOMODULATORS ANTIMETABOLITES

 Type: Rx Drug

  

IMURAN  (AZATHIOPRINE):  Azathioprine is used to prevent organ rejection in people who have received a kidney transplant. It is usually taken along with other medications to allow your new kidney to function normally. Azathioprine is also used to treat rheumatoid arthritis. In this condition, the body's defense system (immune system) attacks healthy joints. Azathioprine belongs to a class of drugs known as immunosuppressants. It works by weakening the immune system to help your body accept the new kidney as if it were your own (in the case of an organ transplant) or to prevent further damage to your joints (in the case of rheumatoid arthritis). Talk to your doctor about the risks and benefits of azathioprine, especially when used in children and young adults.    (Sources: U.S. Centers for Medicare Services, FDA)

  

Results are sorted by Date added.

Key to Ratings: 1=LOW (I would not recommend taking this medicine.)
5=HIGH (this medicine cured me or helped me a great deal.)

Page: 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27


RATING  REASONSIDE EFFECTS FOR IMURANCOMMENTSSEXAGEDURATION/
DOSAGE
DATE ADDED
 
 5  Crohns None, though I do notice that my hair is much thinner than it was 20 years ago! I was diagnosed 25 years ago and have taken Imuran for 10 years following surgery to remove my transverse colon and the subsequent reappearance of symptoms a few months later that required a return to prednisone. For me it has been a fantastic treatment, in addition to bowel symptoms I had severe joint problems as part of the Crohn's and much of this has abated. I still have the occassional 'bad' bowel days, my iron levels are generally a bit low and my joints a bit tender, but as a rule 50mg of Imuran has kept me well. Also, I am a teacher and rarely catch the colds that go around schools. F 47 10 years
7/31/2007
 2  lupus Violent reaction just two hours after I took my first pill. I threw up for three hours almost non-stop and then got diarreah which got so bad that I lost the ability to control it. I got the shakes and would have called an ambulance had my hubby not been home. I don't know if this constitutes an allergic reaction, and I also believe this is probably very rare, but it was the sickest I have ever been. This is not meant to scare anyone and I was so disappointed because I had read here of all the positive things folks had to say about it. I didn't know how to rate my satisfaction with Imuran so I rated it a 2 because it didn't work for me. That does not mean, however, that I wouldn't recommend it for someone else. F 58 1 days
7/28/2007
 5  Polymyositis none I have been taking 200mg per day for 7 months and I continue to improve week to week. I have been able to reduce my prednisone frome 15mg to 10 and am aiming for 8. I was told by a polymyositis specialist that it can take 6 to 12 monthes for the full effects of Imuran to be felt and I think thats right based on my experience. M 60 7 months
7/27/2007
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 3  Crohns Small bowel resection done 8 months ago. Prescribed Imuran as a precaution. Have had Crohns for 8 years. Had the op less than a year ago and was put onto Imuran as a precaution. Now take Asacol and Imuran. Have had no Crohns symptoms and wish I had done the op years ago. Imuran seems to have started taking its toll - nausea, difficulty urinating, increased tiredness, coughing, sore throat. Think its time to try living without it... F 27 10 months
7/26/2007
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 3  Rhumatoid arthritis I instantly had hair loss, noticible in the shower, in my comb, hair falling out everywhere. I have had some blood in my stool but only minimaly. It helped my father immensely so it should help me right? we'll see. M 26 1 months
7/24/2007
 3  Crohn's Disease Significant hair loss, acne, back acne, skin growths Started taking Imuran about 5 months ago. Also did a 6-week Predinzone regimen when I started. I expected hair loss and acne from the Prednisone, but was surpised when after more than 2 months off of it I was still losing tons of hair and had increased acne (something I never had as a teen). I also have acne and strange rashes on my chest and back. I have been using Proactive for the acne, which has always worked for me to clear up minor zits in the past, but I am having no results this time. I feel like I am fighting a losing battle. As I have been on Prednisone in the past, I really feel like the hair loss and acne are worse on Imuran then they ever were on Prednisone. Imuran has moderately helped to control a flare up, but so far it has not been the solution. F 28 5 months
7/19/2007
 3  crohn's disease Periods of hair loss. Nausea. Skin cancers and pinpoint red spots on skin. Extreme lethargy and weakness at times. I've been on 150mg daily for 27years and was always of the opinion that this dosage was determined solely to do with my weight. (I am 61 kilos). I've had a few periods of hair loss, but it always eventually grew back thicker. F 54 27 years
7/18/2007
 1  chron's disease my husband has been on this medication for two weeks. he came home from work feeling ill. I took his temp and it was 104.5. we went to an urgent care connected with our hospital because it was after hours. They said he must have a virus. We attribute this to imuran. He is also taking prednisone. He obviously cannot tolerate Imuran. His temp has been up off and on for the past two days. He had decided to stop taking Imuran today. We see his dr. in three days. Hope we are making the right decision. We can't see taking a pill that is making him ill. This website has been very helpful to see that others have had the same problems. M 42 2 weeks
7/14/2007
 1  Crohn's Pancreatitis, joint and muscle pain, headache, low fever. I was diagnosed with Crohn’s seven years ago. After unsuccessful attempts with Sulfasalazine, Asacol, and Dipentum, Prednisone was the only effective treatment for me but it was causing joint damage. So I tried Imuran (Azathioprine) @ 50MG per day. For the first 12 days all was well. On day #13 I started a low-grade fever, headache and leg muscle pain. This was all minor compared to the almost crippling pain I experience in my knees, ankles, and lower back over the next three days. On day #18 a sudden and terrible pain in my upper center abdomen was added to the mix. This pain landed me in the hospital where I was diagnosed with a pancreatitis. I believe Imuran is magic treatment for many but it is unfortunately not for me. M 49 18 days
7/12/2007
 1  myasthenia gravis Septicemia, when bacteria get into your bloodstream. It is fast acting and hard to diagnose and has a mortality rate as high as 50% and patients can have impaired reason so might not know they are that sick. You basically go into toxic shock and have organ failure. It might be too advanced to cure if you wait for a lab result as it progresses rapidly within days and seems ot escalate fast in the last 24 hours. Different viruses have a variation of morbidity rates. He got 2 different cases of Septicemia. They cured the first one and a more aggressive germ got him a few days after he was taken off life support and within a few days he went into shock and had a heart attack. My father took Imuran for 1 week and on his follow-up appointment (7 days later) he had a fever of 101. He was getting sick and the doctor gave him a prescription and told him that he could fill it in the evening if he needed it. When my mom took him to the hospital's emergency room that evening with a fever of almost 104 and chills, the doctors sent him home with aspirin and an antibiotic, which he may or may not have taken as he was very ill. He seemed to get better and we thought he was taking his medicine but he almost died that Friday as he started going into toxic shock and his Kidneys started to fail, it takes 2-3 days to get lab results. After being on life support his septicemia was cured and he was ok for half a week when a new infection progressed into his blood stream and caused a new case of septicemia, this one he caught at the hospital so it was resistant to many different antibiotics. We are now arranging his funeral. My father was on a different medicine IGG previo M 69 7 days
7/7/2007
 4  autoimmune inner ear disease increasing hair loss, loss of appetite this enabled me to get off Prednisone (finally!) and still be able to hear. I should be on this drug for 6 motnhs to a year (will I have any hair left by that point?) and then maybe taper off if this cures the AIED. If not, on to the next drug. F 39 8 weeks
6/28/2007
 4  Ulcerative Pancolitis Nauseous in the morning, tired a lot, minor hair loss. Flair started 4 months ago, started treatment 2 months ago (Colazal 12 pills/day, 80mg prednisone), flaired up again when Pred was decreased, added 75mg Imuran to treatment and started to decrease 5mg Pred./wk, seems to be helping so far, still not out of the flair, but I am coming off of Pred. and I seem to be doing MUCH better with the Imuran, good choice for me. F 28 21 days
6/22/2007
 5  Ulcerative colitis Tiredness some days, occasional bloating but other than that nothing else. I had a very bad episode of uc early 2006 which required 3wks in hospital.I had just started taking Imuran but it hadn't really kicked in.I had an infusion of Remicade and it was unbelievable how quickly I felt better. That combined with the continued Imuran treatment has allowed me to stay off Prednisone for almost 12 months.I haven't noticed any significant side effects except perhaps feeling a bit tireder than usual but I can live with this if it means I am not going to the toilet 10-12 times a day.I take 200mg per day, 100mg in the morning and 100mg after dinner at night.I also take Salazopyrin 3000mg per day. I am prepared to keep taking this as it has improved my uc and I am able to lead a fairly normal life. I am closely monitiored by my GP with monthly blood tests and if anything wasn't right he would let me know. F 47 18 months
6/15/2007
 5  ulcerative colitis Bruise more easily. More intense cramping with Bms. I was diagnosed with uc 2 years ago. I was put on asacol/sulfasalazine 8 tablets,canasa supositories, none of those worked. I added 40 mg. prednizone to the other tablets, and went on and off this for a year, flaring every time the dosage was reduced. People who use prednizone should question whether they are having side effects from the prednizone or Imuran, (I seemed to have alot more side effects when weaning.) since they may be ending one while starting another at the same time. For me, after my dr. prescribed this drug, it took about 5-6 months before it started having a full effect. I am on a 75mg dosage once in the morning, in addition to the sulfasalazine tablets. I've gone from going to the bathroom 12 times a day with blood and mucus, and explosions, to going 3-6 times a day, with formed stools, no blood, minimal mucus, and rarely a rush to go. I still have a predictable one bad day a week with more intense cramping and thinner stools. I was ready to have m F 36 8 months
6/11/2007
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 4  Chrohn's Hair loss I have had Chrohn's for 22 years, have been on imuran for 2 years. Starting taking remicaid about 6 months ago and feeling really great. About a month ago I started to loose hair, thank goodness I have lots of it. I thought it was the remicaid, but after reading your comments I think it might be the imuran. I am currently on 100 mg daily. F 40 2 years
6/11/2007
 4  ulcerative colitis slight hair loss, muscle pains and spasams, roacea Have been taking Imuran (100mg.) for over two years. Just had my doctor cut me back to 50mg. Don't like all the little things that is happening to my body. It does control my colitis. Hope that one day, I will be able to go off it completely. F 64 2 days
6/5/2007
 5  Ulcerative Colitis Minor hair loss, not sure if it's due to imuran or other drugs This has beena GODSEND. I battled weaning off of prednisone (which never helped) for a year and this was the saving grace I needed to get me functional again. F 29 3 years
6/4/2007
 4  Lupus Bloating, nausea & diarrhea--sometimes fatigue, but that could be the disease or the medicine. Vertigo/dizziness also...not sure if that's a side effect or not? Has helped the joint pain & stiffness--thank God! I can finally move again, began playing tennis again and starting to feel I'm having a normal life! F 34 2 months
5/24/2007
 4  Ulcerative Colitis Strangley I have excess hair growth which no one else seems to mention. Feel am turning into wolf girl. Hair where men get it - hands, stomach, yuk. Very tired. Feel depressed. But... Seems to be working well remission wise. I almost lost my bowel with worst flare ever and was put on cyclosporin and prednisone before starting with azathioprine. Now just on this - 150mg. Mood is very low though, not sure if connected and so tired. Worried about long term side effects and pancreatitis as have had this before from another drug. But if it keeps me from operation, has to be good F 38 2 months
5/21/2007
 4  Neurovascualr behcet's increased skin infections ... weight loss I just started on this medication (also on methylprednisone 32mg/day) ... hey side effects are not what you want but so far are relatively mild (sight nausea is improved with taking it with meals) ... it sure beats the alternatives ... [I am 54 with neurovascular behcet's ... that started in my early 20's so I am way ahead of the curve!] ... it was recently attacking my gut (non UC lesions - causing edema and reactive pancreatitis) and my attacking lower spine and my teeth ... all have improved greatly ... since starting on the imuran ... as steroids weren't controlling it. EVERY DAY ABOVE GROUND IS A GOOD DAY ... M 54 3 weeks
5/15/2007

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