IMURAN Reviews (AZATHIOPRINE)

Average Rating: 2.9 (526 Ratings)

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 IMMUNOMODULATORS ANTIMETABOLITES

 Type: Rx Drug

  

IMURAN  (AZATHIOPRINE):  Azathioprine is used to prevent organ rejection in people who have received a kidney transplant. It is usually taken along with other medications to allow your new kidney to function normally. Azathioprine is also used to treat rheumatoid arthritis. In this condition, the body's defense system (immune system) attacks healthy joints. Azathioprine belongs to a class of drugs known as immunosuppressants. It works by weakening the immune system to help your body accept the new kidney as if it were your own (in the case of an organ transplant) or to prevent further damage to your joints (in the case of rheumatoid arthritis). Talk to your doctor about the risks and benefits of azathioprine, especially when used in children and young adults.    (Sources: U.S. Centers for Medicare Services, FDA)

  

Results are sorted by Date added.

Key to Ratings: 1=LOW (I would not recommend taking this medicine.)
5=HIGH (this medicine cured me or helped me a great deal.)

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RATING  REASONSIDE EFFECTS FOR IMURANCOMMENTSSEXAGEDURATION/
DOSAGE
DATE ADDED
 
 3  Pulmonary fibrosis Mild fatigue. Weakness (harder to stand up from sitting position). No pain, no hair loss. Taking 150mg/day. I don't know if it helps Pulmonary Fibrosis. Doctor says it is helping me. Doctor is gradually reducing my prednisone from 40mg/day, now down to 25mg. I hate prednisone. M 59 4 months
10/27/2007
 4  U/C Nausea, Pain in each side of abdomen, Occasional headaches, loss of appetite, Joint Pain, fatigue Worked for U/C taking 200mg, after 2 weeks at this level nausea so bad requested a drop to 150mg. U/C still under control but Nausea still quite bad. Will keep taking at this level and see if nausea gets better. Taken before for about 5 years and had little or no side effects, unsure why they are so bad this time. M 38 2 months
10/24/2007
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 4  ulcerative cholitis Alot of hairloss and nausea....tight chest pains and headaches, however not sure if fully cause my imuran.I've also notcie joint pain in my knees and major lower back pain. I'm 18 and I've been on 50mg of imuran for about 2 years after my first flare up at age 14. I've been off and on prednisone and my longest remission has been about 3 months. I've noticed that being on imuran has led to fewer flare ups. However, losing my hair is horrible. I used to have really really thick hair now it's really really thin, but I'd much rather live with thin hair then having to constantly use the bathroom. within the past year i've noticed tightening of the chest and constant headaches. I've also noticed joint pain in the knee and lower back pain which forced me to quit playing tennis and basketball which was basically my life. I feel like an old person and it sucks. F 18 2 years
10/22/2007
 5  Ulcerative Colitis Noticeable fatigue, occasional joint pain (wrist & ankle), rarely soreness of tongue Have been taking Imuran for about 15 months now in various does (50-150mg). Once I was leveled off at 150mg I really saw an improvement in my UC symptoms. This drug has been allowing me to finally break my 2-year dependence on Prednisone. Yes the fatigue is tough to deal with at times, but this drug has been a godsend for my UC. M 25 15 months
10/8/2007
 3  Ulcerative Colitis The first week, I didnt have any side effects. 3 weeks later, off the prednisone, I had nausea and headaches all day...or most of the day off an on. Now 3 weeks into it I have quite a bit of hairloss, actual vomitting within an hour or so of taking it and a wierd rash (hives?) on my chin and below my nose. Emailed my Dr. because the vomitting is getting worse, last night I threw up for about an hour, about 1 hour after I took the pill. The rash on my face is tollerable, hopefully it doesn't get worse. The hairloss just started so not sure how bad that will get. Hoping he can give me something for the vomiting but we'll see on Wednesday at my f/u appt. The UC symptoms are pretty much gone and that is what makes me want to stick this out and see if the side effects with lessen with time. F 29 3 weeks
10/8/2007
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 1  UC Nothing while on it, but 2 months after I lost a lot of hair, and suffered muscle aches and joint pain. I'm still losing hair, not as much & have joint pain. It did not work for me, however I did try something that completely worked and thought I'd mention it for those who fall into my category. I was diagnosed in my 30's with UC after I quit smoking. I started smoking again and didn't think much of the correlation with the nicotine and it went away. I sporadically quit smoking off and on over the years and now looking back noticed that's when I got symptoms. I quit smoking 4 years ago again and had symptoms 2 months after. I tried EVERYTHING, including Imuran and steroids with minimal results. Facing surgery (complete removal of my large intestine in two procedures), I started reading studies and found a relationship with the nicotine. I started to smoke again (1 day before my 4 year anniversary of quitting) and with 2 1/2 weeks, I barely had any symptoms. I have been smoking (only about 4-5 cigarettes in the evenings) now 2 months and am off all drugs and symptom-free. I've been told this only works for that small group that were F 45 4 months
10/6/2007
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 5  autoimmune hepatitis I have been on azathioprine for 3 yrs with virtually no side effects. After being diagnosed (Oct. 2004) was put on Prednisone and azahioprine. After 18 mos. went in remission and off medication for 2 months and then had relapse. Back on prednisone and doubled the azathioprine (100 mg daily). Liver numbers normal in March 2007. Off prednisone, still in remission and hopefully off azathioprine in October, 2007. F 77 3 years
9/13/2007
 2  ulcerative colitis pancreatitis After 17 days of taking Imuran, I developed severe stomach pain, which was diagnosed as pancreatitis. I was hospitalized for two days and told never to take Imuran again. It was too soon after beginning Imuran to know whether it was helping my colitis symptoms. F 30 17 days
9/10/2007
 4  Lupus w/kidney involvement In the beginning I was dizzy,lethargic etc. I had hair loss but all of these could have been from predisone, plaquenil or even Lupus. A severe bout of throwing-up once caused me to be admitted in the hospital. I have been having back pain on and off. The pain is getting worse. I am also having weakness in my legs, ankles and arms. I'm losing weight and a feeling of something isn't right. Would like to know if anyone who has taken this drug for a while has noticed these symptoms. Also, I am African American and have noticed a definite change in coloring of my skin. First, it was only in the summer. I'm only on 3mg of prednisone a day. 150Mg of Imuran and 200mg of plaquenil. I am trying to figure out what is causing the feeling of malaise I've been experiencing recently. I don't think it is the prednisone or the plaquenil. Imuran has really helped, but I wonder if it has turned toxic to my system. It is definitely a drug with advantages. email if you can give any information. F 60 6 years
9/4/2007
 5  crohns I have had crohns disease since by 20's and was on a zulfidene drug for many years. Then Went on Imuran have been on it for over 18 years.It was working very well, until now. Was out of remission in April and to go on Predisone 50mg, reduced now to 10mg. Meanwhile my doctor increase the imuran to 125, started noticing my feet was getting numb, didn't think anything of yet, until slowly it started getting worse. Told my doctor he thought it was the Imuran. Slowly getting off the predisone. Finally went to the hospital due to the numbness and tingling, etc in both feet, said I had neuroapthy. Went to my Dr. and she put me on this drug for it, made me very dizzy, stopped in one day. Finally, went to a neuro Doctor, comfirmed i had this disease combination of having Crohns and the Imuran. When your auto-immune system is so low, you get everything, have had shingles, thyroid problem now. Your white blood count has to be checked every 3 months which I do, because of this drug. I am telling m Imuran is a very good drug for crohns, but long term use can be very damaging it seems. I have problems with it now and I feel it is time to change to another drug for my crohns. Hopefully my doctor can give me something to keep my crohns in check.I have been taking this med for at least 24 years. F 62
8/31/2007
 1  Ulcerative Colitis (pan UC) Diarrhea was extremely severe, got sick, fever, flu, etc. waking up at night to go to bathroom 20 times per night approx. unable to hold down food AFTER taking Imuran. When I stopped taking Imuran, many of the symptoms vanished. (I was at that point only on Prednisone, previously had been taking the two drugs.) That is, the number of times I had to use the bathroom (diarrhea) was cut in half to 10 by the first day and down to two by the second. Be careful with this drug! I stopped after 30 days. F 45 30 days
8/28/2007
 5  Ulcerative Colitis Although I felt tired and drained and experienced hair loss, I feel some of this may have just been due to how severely ill I was by the time I finally had imuran prescribed for me. The last major attack of ulcerative colitis required 2 hospitalizations and took almost 5 years to bring under control. If the alternative to coming off imuran is to feel as sick as I did before taking it, I will stay on it as long as my doctors feel that it is safe. Being fatigued a little earlier in the day is a small price to pay compared to what a full blown attack does to your life. I put on almost 90 pounds with long term usage of prednizone (75 off after 4 years)and dealt with all the psychotic side effects of that drug. I just sleep a little earlier, keep a positive outlook, smell the roses every day and am grateful to imuran for giving me back my life. F 47 7 years
8/27/2007
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 3  Crohn's much more tired, sore/achy joints in toes, shoulder, and neck, headaches more often, and hayfever allergies seem to be worse Definitely more tired, it's tough to stay awake all day without taking a nap which I never needed before. I don't like the sore/achy joints especially considering I am used to being very active, but it's better than being in the hospital and having surgery, which I have had twice. I'm still undecided whether I want to stay on this or talk to my doctor about trying something different. M 33 4 months
8/27/2007
 2  Ulcerative Pancolitis Increased fatigue, nauseous, hair loss, loss of appetite, headaches, and I think causing acne-never had it before Imuran worked to get me off prednisone. After reaching 150mg I really started experiencing the side effects; hair loss, loss of appetite and bad headaches. My doctor said to stick with it, so I have. I am still tired a lot, I still experience hair loss, appetite is gone, BUT over time the headaches stopped almost completely and I do not feel as nauseous as I did. Acne on my face has now showed up? Not pretty and I can only assume it’s because of this drug-I have never had acne before. If you can stand the side effects hang in there, it does get a little better with time. For me it seems to be doing the job on the UC and keeping me off prednisone-which is great. This is not a miracle drug for me, it has a ton of side effects and it has not made the symptoms of UC go away completely, but it seems to be the only thing working for me. F 28 3 months
8/27/2007
 1  Ulcerative Proctitis/Colitis Hair loss, joint & muscle pain - oddly enough these came 2 weeks after going off the drug. I had no side effects on the drug. I've heard that it takes 2 months to start working and the same to get out of your system. I'm hoping the side effects stop soon, escpecially the hair loss. This drug had no effect on my UC. F 45 100 days
8/21/2007
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 4  Crohn's Abdominal pain, hand pain, joint pain in the feet and heels mostly, tired, my eyesight seems to be getting worse. I'm getting older but this is all coming on too fast I think. 2006 was a bad year for my chrohn's. VERY difficult being a mailman. Imuran has helped but still have several BM's especially in the morning and nearly always diarrhea. Livable now though. The joint pain is worse if I have been still for a few minutes. I can hardly walk but it loosens up after a bit of walking. Gut pain is almost severe and much sharper than normal Chrohn's pain. Feels like a "stitch" in the side did when I was a kid. M 47 1 years
8/17/2007
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 2  Ulcerative Collitis x 5 yrs vague tiredness until 30th day on 50mg/day. Then became extremely tired to the point of needing bed, decreased appetite, mild nausea, stools became pure liquid, achy, felt I was being poisoned and quit taking it - then notified my MD the following Monday Very disappointed that I could not take this medicine. Have f/u appt with MD end of August. F 61 1 months
8/15/2007
 2  Crohn's fatigue, insomnia I was diagnosed in February of this year, but had suffered with it for at least 3 years prior. I was hospitalized for 2 weeks and had surgery to remove two sections of my intestines. I started Imuran at 50 mg per day and they have steadily increased it to now 200 mg per day. But I'm always tired, especially in the early afternoon time, but when it's time for bed, I can't sleep. I end up staying up late doing laundry or something else. Besides that, it really hasn't helped my symptoms at all. I still have the same things, except for the excrutiating pain I had in the several months prior to surgery. That has eased off since then. The doctors are talking about starting me on steriods to see if that will help. F 37 6 months
8/10/2007
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 5  severe eczema zero side effects I broke out in unGodly itchy full body rash out of the blue when I was 54. Major prednisone courses, cyclosporine megadoses, horrendous side effects, total misery. Switched to Imuran a year later..total remission and off it as of yesterday. Wish me luck. M 57 1 years
8/9/2007
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 3  crohn's fatigue, no appetite (unlike prednisone!), depression (don't know if from this or just 'cause am a sad) I started about a month ago at a 100mg dose(2 pills), taken once a day. Since then I have been in remission, with only minor bloatedness and cramps, but apperently it takes 3 months for this to work, so I am planning to carry on taking it and see what happens. Thanks for a great website! M 25 1 months
8/2/2007
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