IMURAN Reviews (AZATHIOPRINE)

Average Rating: 2.9 (526 Ratings)

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 IMMUNOMODULATORS ANTIMETABOLITES

 Type: Rx Drug

  

IMURAN  (AZATHIOPRINE):  Azathioprine is used to prevent organ rejection in people who have received a kidney transplant. It is usually taken along with other medications to allow your new kidney to function normally. Azathioprine is also used to treat rheumatoid arthritis. In this condition, the body's defense system (immune system) attacks healthy joints. Azathioprine belongs to a class of drugs known as immunosuppressants. It works by weakening the immune system to help your body accept the new kidney as if it were your own (in the case of an organ transplant) or to prevent further damage to your joints (in the case of rheumatoid arthritis). Talk to your doctor about the risks and benefits of azathioprine, especially when used in children and young adults.    (Sources: U.S. Centers for Medicare Services, FDA)

  

Results are sorted by Date added.

Key to Ratings: 1=LOW (I would not recommend taking this medicine.)
5=HIGH (this medicine cured me or helped me a great deal.)

Page: 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27


RATING  REASONSIDE EFFECTS FOR IMURANCOMMENTSSEXAGEDURATION/
DOSAGE
DATE ADDED
 
 5  Crohn's Disease None in 10 years. Crohn's was diagnosed in 1975. I had many resections. In 1997, I had to have an ostomy. I now only have 4 feet of intestine left when I started taking Imuran. THANK YOU GOD FOR THE IMURAN !!! I am now going to nursing school. I might just have a chance at life after all. F 52 11 days
2/18/2008
 4  Crohns 20 lb. weight gain, joint/muscle pain in feet, legs, hips, take naps when I never use to. Don't notice depression but I am also on Paxil. I am at 100mgs. 45 and I feel the pain of an arthritic 70 year old. Have to "walk it off" when I get up from office chair. Have even fallen asleep at my desk! Have Drs. appt. in March '08. Anxious to hear if he will adjust dosage. He says benefits outway side effects....I'm not so sure. F 45 6 months
2/18/2008
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 3  Crohn's disease Horrible nausea, fatigue, sensitive skin, migraines, alcohol intolerance, drop in both white and red blood cell counts and constant sinusitis As i understand it Imuran prevents your body from creating antibodies against Remicade. The doctors put me on Imuran the same day as the put me on remicade and the nausea was pretty horrible, i've spent much of the last 5 months in bed - but i've been almost symptom free from the original illness as well. I quit Imuran two weeks ago and the nausea is gone, so are the migraines. I have, however, had a pretty upset stomach for the last few days, but i am hoping it is just a coincidence... Doctors say it's important to stay on Imuran for 6 months after you start remicade, and the wean off it so remicade can work its wonder by itself. The bad balances out the good with imuran i think. F 24 5 months
2/16/2008
 2  Henoch Schonlein Purpura Began Imuran while tapering from extremely high dosages of Medrol (like prednisone). After 1 month (Dose increased weekly from 50mg-200mg)began having neck pain causing headaches (might be related to misalignment in neck) A week later when a cold hit I had severe knee and foot pain along with fatigue. Dropping dosage back down to 100 mg has reduced the symptoms to cramping in my feet and hands and the headaches. With all I've read I am hoping my doc gets me off this soon (though I'll be stuck on the Medrol for at least another couple months). One doc told me that it takes a month or two for the Imuran to build up to effectiveness. I guess that would mean for all of us who survived the initial dosage without problems have to wait a while to see what side effects might be there. Overall, I can't tell if the Imuran has had any effect on my treatment, if the corticosteroids have been doing the trick (since getting out of the hospital), or if the disorder has run it's course. M 34 6 weeks
2/14/2008
 4  Ulcerative Colitiis Some hair loss but not severe. I seem to tollerate this medicine fairly well. White and Red blood cell levels are below normal and notice less stamina. But this is still much better than the alternative, which is UC in full active attack. Still have minor bleeding problems and not all inflamation has dissapeared. Some days better than others regarding typical symptoms. I take 200 mg/day at dose of 2 mg/kg body weight. Adding maximum dose of Asacol (4x3time/day) to make this combinination work better. Without both together neither works well. Without both of these drugs my life really sucks. I am greatful to have it. I also recommend finding a doctor with a modern approach to UC treatments. M 48 8 months
2/12/2008
 2  non-specific autoimmune disorder Belly ache I started on 50mg and tolerated it well. After 2 weeks, another 50 mg. were added. After two more weeks, the target dose of 150mg. was reached. About a week later I had bad stomach aches similar to what I used to have when eating acidic foods. Since I'm on 20 mg. of Achiphex 2X day for GERD, we didn't think this would be a problem, but it was. Staggaring the dose didn't help either. Now we're trying mercaptopurine. F 55 30 days
1/27/2008
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 2  Crohn's High fever (103+), extreme knee joint pain (can't walk without crutches and/or help) This was the first drug prescribed after being diagnoised. After 2 weeks, the symptoms appeared. The doctor refuesed to believe it to be Imuran. After trying Asacol (didn't work) I said I'll prove Imuran is bad for me. I took one pill - mistake. By that evening, I had the high fever and extreme knee pain. The fever lasted about 5 days and the knee pain lasted over two weeks. This occured 6 years ago. Ever since Imuran I have had joint pain but can't prove it to be the cause. M 40 14 days
1/25/2008
 5  Ulcerative Colitis White cell count too low about once a year. This medication gave me my life back! After 7 years on and off Prednisone (with significant side effects), I moved to Chicago and found a GREAT doctor who weaned me off Prednisone and on Imuran. It took about 3 months for the Imuran to start working, and was able to wean off of the steroid. I don't have any side effects other than occasionally my White Cell count goes a bit too low. My doctor has me go off the med for 5 days, then repeat my CBC, then go back on. I only wish I could have started this drug with my first doctor! I spent 5 years trying to get stubborn body weight off (after years of Prednisone, my matabolism is so screwed up). I'm healthy, at a good weight, active physically and socially, and I LOVE LIFE !! F 40 7 years
1/24/2008
 1  Ulcerative colitis Hair loss, fatigue, and it took longer to get over any kind of sickness. I have found natural supplements that have helped me discontiune Imuran. I am taking a digestive enzyme and probiotics. I feel so much better. I'm not saying this is the fix for everyone, but do not rule out natural supplements. F 31 2 years
1/24/2008
 2  U C pancreatitis It did not work for me. Around day eight I got savear stomach pain every time I ate. I was in the hospital for four days. M 51 8 days
1/18/2008
 2  UC massive hair loss After taking the drug for 6 months plus remicade for 5, I"ve found that my hair has decreased in volume and it's scary. It's about 1/5 of what it used to be, and it doesn't seem like the hair loss will stop anytime soon. Every time I take a shower, I pull out handfulls of hair. This should not happen to a 19-year-old. So I recently told my doctor that I do not want to take it anymore. Maybe it will work for others, but it didn't for me. Not to mention I've started having another flare on the drug. F 19 6 months
1/16/2008
 3  UC I was hospitalized in October 2007 for 10 days because I had been sick again for 3 months and not responding to oral prednasone, the dr put me on Imuran, I broke out with such bad acne, nausea, hairloss and sever joint pains, i stoped the medication mid November because I would have been bald within a few months. The dr agreed. I am still experiencing the side effects and it's Jan 08. I still have hair loss and sometimes I can't even walk up a flight of stairs. My muscles and joints get stiff and I feel 90 when im only 27. I hate the fact that we have to take meds to get better but then it makes you worse. F 27 1 months
1/9/2008
 4  IBD (unsure which kind) fatigue, dry skin, more colds/flu than very dry hair (but no loss yet) Perhaps it is just vanity- but Imuran works better than prednizone for me as well as not having to be a fat cow. I havn't lost any hair yet but after reading all this Im scared I will. I have been taking Omega 3 flax and fish oils + vitamins for about a year-so maybe that has helped with the hair thing. After being on this for 3 months and being totally better I had a slight flare again and upped my dosage. I'm currently in the process of trying to cut out wheat glutens and sugar and that seems to have helped after only a few days too. Good luck everyone keep your heads up and your strength up! F 32 3 months
1/3/2008
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 1  Crohn's Lower back discomfort, fatigue, joint pain in big toe, vision got a little worse. 3 weeks into taking imuran, had nausea and vomitting (w/ some blood) for 2 consecutive nights about 6-7 hours after dose...doc took me off immediatly, and all symptoms went away next day...and felt much better when i started prednisone. I didn't notice any improvement in my crohns symptoms on this drug. The nausea and vomitting were horrible and unexpected (no, I did not have a virus... I was fine during the day and evening)...but I am glad they happened cause it's a reason to get off it before i wasted too much more time, and I will now hopefully move on to something that will actually work for me (6 months since diagnosed and still looking)! And now I know that the other little side effects I had were related, and not due to something else like laziness or a bad night of sleep! F 34 3 weeks
1/2/2008
 5  Ulcerative Colitis extreme fatigue, joint pains, dry skin, increased appetite, tender abdomen, and slight hair loss, mood swings even though i had side efect after 2 weeks of taking Imuran i saw results, im taking prednisone(30mg) at the same time those werent working properly until i started taking Imuran (50mg) this is the best pill ive taken so far. i have stage/level 4 UC. and now from taking Imuran i have no stomach pain or going to the washroom 8-12 times a day. F 12 18 days
12/25/2007
 2  crohns severe headaches, bad pain in back,chest,stomach and hair loss, and sick stomach, dizziness, and depressed. It helped the chrohns pain and symptons but proved dangerous to my health otherwise. I really wished I could have handled it better. I was diagnosed just a few months ago. I don't know what will work. Wish this would have. F 30 21 days
12/21/2007
 1  Lambert Eaton Syndrome back pain, flulike symtoms, severe chills, and shaking, fever, headaches, mouth and tonsil sore, rash, itching, diarrhea Off Imuran for 36 hours now and still itching badly and diarrhea. F 76 3 weeks
12/14/2007
 3  Crohn's and reactive arthritis Fatigue. Some severe stomach pains as dose increased. Constipation and bloating. Not sure yet about this drug. Have been slowly increasing over last three months. Was sitting pretty until recently when dose was increased to 125mg. Now starting to experience severe stomach pain, my fingers feel like they're made of glass and I have a general feeling of unwellness (whereas when on a lower dose I was feeling the best I had for months). Dr insists dose needs to be increased and that it won't 'work' on less than 150mg. Seems to be helping with arthritis, inflammation not as severe and I'm now down to 3mg prednisolone but I'm finding it a frightening drug to be on especially now that I'm experiencing some weird things! F 35 3 months
12/11/2007
 4  Autoimmune hepatitis I have had some hair loss, change of texture in hair, extreme fatigue. I have had bouts of extreme joint pain. After being on it for approximately 4 years I am slowly becoming crippled by extreme joint pain in my hands fingers and wrists. over the last 5 months I have developed several locking fingers on the right hand, and it is now spreading to my thumbs. When not totally locked in either opened or closed position, the large joints at the base of each digit is extremely painful to touch, making it hard to accomplish many tasks. I do not know if this is another aspect of my autoimmune journey or if it is the medication. I have lost 2 dental bone grafts in the last two years after developing serious infections, about 2-3 months into each graft. I showed no serilogical indications of having these infections such as elevated WBC's. The positive part is: Prior to starting the prednisone (off that now) and the imuran, I was so ill that it was hard for me to walk across the room. I was constantly nauseated, weak, tired and had over all lethargy. My liver enzymes were in the 1040 rang for one, and 980 for the other. They have been normal for several years, except when I went off the medication and went out of remission. Over all I think the imuran did improve my life. I was so ill prior to taking it. I have had some really good years and was well enough to enjoy both my daugters weddings. F 55 4 years
11/11/2007
 4  ulcerative colitis only fatigue the only thing makes me satisfied with imuran is stop taking steroids , because of imuran i started to have a normal life ,i don't know till when , but thanks allah(god)any way.don't forget to pray for every one who helped to invent this and other medicines. M 33 5 months
11/3/2007
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