IMURAN Reviews (AZATHIOPRINE)

Average Rating: 2.9 (526 Ratings)

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 IMMUNOMODULATORS ANTIMETABOLITES

 Type: Rx Drug

  

IMURAN  (AZATHIOPRINE):  Azathioprine is used to prevent organ rejection in people who have received a kidney transplant. It is usually taken along with other medications to allow your new kidney to function normally. Azathioprine is also used to treat rheumatoid arthritis. In this condition, the body's defense system (immune system) attacks healthy joints. Azathioprine belongs to a class of drugs known as immunosuppressants. It works by weakening the immune system to help your body accept the new kidney as if it were your own (in the case of an organ transplant) or to prevent further damage to your joints (in the case of rheumatoid arthritis). Talk to your doctor about the risks and benefits of azathioprine, especially when used in children and young adults.    (Sources: U.S. Centers for Medicare Services, FDA)

  

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Key to Ratings: 1=LOW (I would not recommend taking this medicine.)
5=HIGH (this medicine cured me or helped me a great deal.)

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RATING  REASONSIDE EFFECTS FOR IMURANCOMMENTSSEXAGEDURATION/
DOSAGE
DATE ADDED
 
 2  myasthenia Swollen, blistered sore tongue; severe headache (migrane) I was advised to take this for the next 6 months so that I could get off of Mestinon for my condition. I would love to hear from anyone who could offer advice. At this point, I have stopped taking any meds for this condition. F 57 9 days
5/31/2008
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 2  Crohn's nausea, vomiting, headaches, join pain Started off with 75mg after dinner, was okay for 2 weeks, had occasional headaches, then had nausea and vomiting 4 nights in a row. Went off of it for 5 days per doctor's orders, and then started again taking half a dose at bedtime. Was fine for another 2 weeks, but then started having nausea and vomiting, as well as join pain in my knees and hands. F 26 1 months
5/27/2008
 4  Ulcerative Colitis Severe joint pain in hands, arms and ankles, tiredness, more suseptible to infections, some hair loss at the start but this has decreased over time, sensitive teeth, mood swings, headaches. I started imuran after my worst flare up 6 months ago, which required hospilisation for over 2 weeks and took 3 months from my life. I nearly lost my whole bowel. i was dependent on prednisolone for nearly a year and had put on over 2 stone which i have now lost, so glad to be off the steroids i had terrible side effects from them, didnt sleep for about 3 months. Since starting on imuran my uc symptoms have decreased, minimal bowel pain and less bowel movements, has given me my life back without the operation, apart from the joint pain and tiredness but ill suffer it as long as i can, never want to be that sick again and want to avoid operation for as long as possible. F 23 6 months
5/26/2008
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 4  UC redness around neck and face, bloated moon face could be from the prednisone, tightness in chest if I take a deep breath and stretch, mood swings, loss of interest in things I once liked (Could be from Iraq, who knows) I feel like it is working well for me. I no longer have blood in my stools. No more severe cramping that has put me in the hospital 3 times now. I went to the GI yesterday and I am finally coming off prednisone, im nervous cuz everytime I do, everything comes back...This is the longest I have ever been on it though. Started at 50mg and came down every 2 weeks, 40, 30, 20, 10, 5...It turns out im alergic to Asacol which I know is the prefered drug for UC. All in all, I like Imuran so far.. Good luck everyone. M 23 2 months
4/29/2008
 4  CROHN'S DISEASE hair loss, chills, fatigue, nausea, but my biggest complaint is that i have severe muscle aches over my entire body that i cannot get rid of. This medication has done wonders for my crohn's and have not had any flare up's in the entire time i have been taking it. allowed me to get off of steroids after an entire year on them. F 26 12 months
4/26/2008
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 1  chrons disease major hair loss no one warned me I could lose my hair,if they had I would have declined using this drug F 32 90 days
4/26/2008
 4  Wegener's Granulomatosis Vasculitis I have the funny feeling that it is affecting my nervous system. I seem to be edgy and can not cope with stress very well. I also feel very anxious and nervous most of the time. I noticed that I started feeling this way after a feww months of taking Imuran, although there could be other factors (stressors) involved. Taking it for Wegener's Granulomatosis Vasculitis. It has helped my condition significantly. Used to be on cytoxan or metrotraxate with prednisone. Would like to hear from other people feeling the same side effects. M 47 9 months
4/9/2008
 3  UC tiredness, redness in face, sensitive teeth, hair loss, achy joints, mood changes, weight gain, bloated, moon face, night sweats, blood sugar rise...the latter of these prolly from steriod usage. Started Imuran 100mg daily, while hospitalized in dec 07; in addition to 40mg of Prednisone then tapering down 5mg every 2 weeks. I was extremely dehydrated/anemiac and had severe UC that could not get into remission w/out spending 3.5 weeks in the hospital. They kept talking about surgery until they put me on Imuran and I did a 180 turn for the better! Has helped tremedously in keeping inflammation at bay. Recently have had some inflamation in rectum area, and have been bumped back up to 15mg daily of prednisone; then will very slowly taper over next few weeks. Not sure if my side effects have been from the steriod or Imuran itself; but was curious about my hair loss and wanted to see if others have experienced it. I used to have beautiful wavy hair, now very thin and kinky and can not get it to do anything I'd like it to do! Very upset by this as well as my "bloated" appearance. Have been very irritable lately and I was a very happy and friendly person once out of the hospi F 27 4 months
4/9/2008
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 2  Ulcerative Colitis tightness in chest and difficulty breathing. I have a flare everytime I come off from prednisone. Dr wanted me to try imuran. After only taking 25 mg on the 6th day I noticed tightness in my chest. Day 7 was worse as I wasn't keeping anything down (vomiting constantly). Was hospitalized for 3 days. White blood count very high and Red blood count low. Had blood transfusion. I'm considering surgery. Hopefully being on prednisone for a few months will buy me some time to get a "real" GI doctor that knows what they are doing - like at Mayo Clinic in Minnesota - I hope. I've only got 5 weeks of high school left before graduation. I can't be sick for that! I will definately be doing something this summer. UC is an awful disease and I hope no one else gets it! F 17 7 days
4/7/2008
 5  colitis when i began taking this drug i was only taking 1 50mg pill in the morning. i did not experience any side effects. after a few weeks my dose was increased to 2 50mg tablets in the morning. i felt intense nausea after taking the 2 pills so i began taking 1 in the morning and 1 at night. other than that i have experienced no other side effects...THANKFULLY!!! F 24 3 months
4/2/2008
 5  Excema In the first couple of weeks the dose was a bit high and I got fever. Then I stayed at 150mg per day for about a year. Then I reduced to 100mg for the next 18 months. That's the story so far. I couldn't sleep because I sweated at night before I started on Imuran. So I was tired all the time and itchy with excema. Captain Imuran came to the rescue though and I have had no side effects since that initial hiccup with fever. I can't remember what dose I was on that gave me the fever - perhaps 200mg/day? M 36 2.5 years
3/31/2008
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 1  Lupus Nephritis Extreme lowering of WBC count (800), heavy hair loss, joint pains, needed blood transfusions to regenerate bone marrow not suitable for me, may be some biochemical tests are required to determined its metabolism in certain individuals. F 33 40 days
3/31/2008
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 5  Ulcerative Colitis none I believe the side effects some people assume with Imuran, are more symptoms of being ill. After having been on the drug for a while and eating healthy, I can safely say there are no side effects in my case. I am at lower does and everyone is different. I have taken for about 4 years. Had some gaps where I stopped taking (and got sick) but now on regularly every day 75 mg for about a year. I also take Lialda (2 pills per day). Not sure which or both are helping but overall healthy. 33 4 years
3/13/2008
 4  Ulcerative Colitis Fatigue, mild nasea when upping the dose from 50 to 100 mg, possible depression although it may be unrelated It took several months for it to begin working but I haven't had a flare since. I take the whole dose in the morning along with Colazal. I also depend on regular doses of fiber supplements. I take the fiber in between colazal doses. I have found that I need the fiber just as much as the drugs. I take 6 capsules twice a day. Definitely worth a try if you're not taking fiber. F 33 1 years
3/6/2008
 4  U/C nausea, weakend immune system, anemia After 2 days on the drug, I was so nauseous that riding in a car would make me throw up, I ended up almost bed bound because every time I went around someone, I would get sick, I still ended up having surgery for impacted intestine, my anemia was so bad that I was taking 5 iron a day, and the nurse was always complaining (like I had any control.) I stayed on Imuran as long as I could, and with my last hospitalization I begged for a new treatment, since I couldn't take this anymore... It wasn't the miracle I had heard it was - at least for me. F 46 9 days
3/5/2008
 5  UC Dry skin on face I was seriously bad with ulceratice colitis, from bleeding through the bowel, being in hospital, sleepless nights, being laid up on the settee for 10 months, sleeping and running to the toilet, my life was a nightmare. Then i took immuran and it stopped the bleeding almost immediatley and with a few months i was back to normal once i got off the prednisolone steroids. M 25 2 years
2/28/2008
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 1  lupus/ulcerative colitis took 50 mg for first 14 days, then experienced severe nausea, and vomiting for several hours after taking on subsequent days. Also feverish and increased joint and lower back pain. Nausea and vomiting came on after one hour of dosing. No more for me! F 48 18 days
2/27/2008
 4  autoimmune hepatitis hair thinning,texture changed to fine from course;joint pain, particularly knees; upset stomach seems to be keeping the hepatitis in remission; prednisone was very effective, but side effects were horrible F 58 1 days
2/26/2008
 3  Crohns Headaches, Fatigue, Nausea, Joint Pain in Hands, Slight Hair Loss Ive been on Imuran for 8 weeks. I went from extreme pain every day to almost none. My gi symptoms have gotten better as well. I just worrie about the long term side effects of this medication as i want to try to have a baby in about 6 months. I guess i will have to go off the drug. F 23 8 weeks
2/26/2008
 4  crohns Eyesight deterioration, visual distortion briefly, fatigue, tremble. On Imuran 200mg daily along with 20mg Pred, Imuran dosage went to 200mg from 150mg when Pred reduced from 30mg to 25 and then 20mg, hoping to drop to 15mg pred shortly an onward. Six months since diagnosis of microscopic polyangitis (vasculitis), not sure what side effects are Imuran, Pred or related to my MPA, can I have my life back now please? M 46 6 months
2/22/2008

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