IMURAN Reviews (AZATHIOPRINE)

Average Rating: 2.9 (526 Ratings)

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 IMMUNOMODULATORS ANTIMETABOLITES

 Type: Rx Drug

  

IMURAN  (AZATHIOPRINE):  Azathioprine is used to prevent organ rejection in people who have received a kidney transplant. It is usually taken along with other medications to allow your new kidney to function normally. Azathioprine is also used to treat rheumatoid arthritis. In this condition, the body's defense system (immune system) attacks healthy joints. Azathioprine belongs to a class of drugs known as immunosuppressants. It works by weakening the immune system to help your body accept the new kidney as if it were your own (in the case of an organ transplant) or to prevent further damage to your joints (in the case of rheumatoid arthritis). Talk to your doctor about the risks and benefits of azathioprine, especially when used in children and young adults.    (Sources: U.S. Centers for Medicare Services, FDA)

  

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Key to Ratings: 1=LOW (I would not recommend taking this medicine.)
5=HIGH (this medicine cured me or helped me a great deal.)

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RATING  REASONSIDE EFFECTS FOR IMURANCOMMENTSSEXAGEDURATION/
DOSAGE
DATE ADDED
 
 1  auto immune hair loss, acne, warts, yellowing of skin, nausea Imuran didn't work for me. I don't know anyone who's been helped by it either. F
10/11/2008
 5  Ulcerative Colitis Recently noticing hair loss; not sure if it's from Imuran or from stress. Hair thinning considerably near part at hairline. Sometimes feeling of general unwellness, but nothing major. Removal or biopsy of several "dysplastic" moles on my torso. Very fair skinned, tanned in tanning bed on occasion through HS and college. So far all labs for liver function, etc are normal. This drug has put my UC in remission. Diagnosed in 2001-2002. I tried discontinuing it and relying solely on the Colazal about 8 months ago (9pills/day) but symptoms returned after a month. Resumed Imuran and symptoms stopped after 8 weeks. No flares since as long as I take it. Take 3 pills once a day and 9 Colazal pills (3/3x/day) F 29 4 years
10/9/2008
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 5  auto immune hepatitis Upset stomach every morning, like morning sickness when you are pregnant. I am having hair loss which i believe that the meds are the cause. I am greatfull to be able to function on a daily basis, before I had the disease under control it was horrible. So although there are side effects, I am alive and well. Only major issue I have is that I want another child and I cannot be pregnant and on these meds. F 30 10 months
10/3/2008
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 1  autoimmune disease A tumor, yellow skin, vomiting, massive hair loss, and I was always sick and got acne too. I wouldn't take this again; it's not safe.
9/22/2008
 4  Crohn's Disease Headache I've had Crohn's disease for about 26 years now. Have been on Asacol for most of that time but would have repeated flare ups. I started to develope pretty bad reactions to the prednisone used to control the flare ups so my doctor put me on Imuran. It kept me flare up free for about 4 years until I convinced him to try to get me off the Imuran. I had been on 100 mg. and he reduced the dosage to 50 mg. Within 3 months I developed another flare up. Went up to 75 mg. of the Imuran and have felt great ever since. F 56 5 years
9/17/2008
 3  Ulcerative Colitis For the first two weeks, I noticed no side effects at all. Now, my knee joints ache but are okay ater taking Ibuprofen. I am also tired and don't sleep real well. At this point I'm a bit concerned about the fact that my asthma (which I've had under control for years with a steroid inhaler) seems to be acting up. Now this could be related to the fact that it is fall and there are more alergens in the air. I have had significant bleeding for 3.5 years, with few other symptoms. Then began having symptoms - abdominal pain, lots of gas, etc. and flare ups. Tried over the counter and internet advertised remedies, none worked. Then found a group of Gastoenterogists, who prescribed one by one all of the prescription remedies without side effects, none worked. My doctor I would need to take the Imuran and did baseline blood work. She also gave a prescription for Entocort and Lialda. Though I had taken all the other Lialda like drugs - since it had a different formulation, thought we should give it a shot. She wasn't sure the Entocort would work at all. I began it at 3 per day for 2 weeks before starting the Lialda. Entocort was like a miracle drug and I began to think it was the answer. Then began the Lialda and right away all symptoms returned. After 10 days stopped Lialda - I was then taking 2 Entocort a day and began Imuran. Since Imuran is supposed to take 4-6 weeks to get up to speed, I F 60 21 days
9/12/2008
 1  Crohn's Disease Tumors, warts, fatigue, violent vomiting, jaundice, acne I wouldn't have taken it if I knew it could give me cancer. M 32 3 months
9/7/2008
 3  Crohn's Disease Headaches, nightmares (not sure if these are related to Imuran or not), occassional nausea, itchy skin So far I've only been on imuran for 5 weeks. I'm not sure if the side effects will get better, worse, or stay the same as my body adjusts but so far it's not too bad. I haven't noticed the Crohn's pains getting better but I haven't been on Imuran very long yet. If the side effects I listed are the only ones I get and the Crohn's pain decreases I'll be one happy camper! :) F 27 5 weeks
8/30/2008
 1  colitis massive hair loss, the most fatigue i've ever experienced, weakness, aches, acne, warts
8/24/2008
 1  Crohn's colitis Neoplasia, extreme nausea, infections of all kinds, sore throat and a cold the whole time I was on it, extreme weakness, extreme fatigue, so tired I could barely move, it was like my body was just shutting down, warts all over my body and face, acne. It doesn't work, just suppresses your entire immune system, which basically assures you're going to get infections and things like that and it also makes you sick and can possibly give you skin cancer, leukemia, or lymphoma. You have an immune system for a reason. It's pretty stupid, I think, for doctors to give you a drug that shuts down your entire immune system. This might work for some people with very mild forms of the disease. For people with serious or even severe forms, however, in my experience, it doesn't work at all. Probably the people for whom it works are only experiencing a placebo effect and could get the same effect from a sugar pill--without the serious risks, of course. F 7 months
8/22/2008
 1  Crohn's or UC hair loss, acne, weakness, bruising, tiredness, skin growths, M 32 3 months
8/5/2008
 1  Autoimmune haemolytic anaemia Fatigue, jaundice, Hair thinning (no loss yet), Interstitial pulmonary infection, Excessive sweating My mother has been on Imuran for about 2 months and so far has been hospitalised for a severe pulmonary infection. She is 69 and the doctor that was called out to see her at home seriously didn't think she'd make it. She is tired all the time and suffers with yellow jaundiced eyes. She hasn't lost any hair yet but it's thinning and only time will tell I guess. My mother is a get-up-and-go woman who cannot sit still but since she has been on Imuran she has lost her zest for life and I am very worried - I have never seen her like this before. We are at present compiling reserach on alternative treatments. F 69 2 months
8/2/2008
 5  microscopic colitis Nausea if I don't eat a hearty breakfast when I take the Imuran. I didn't respond to traditional drugs or diet for microscopic colitis, even Prednisone. Imuran has saved my life. I started on 50mg, and then 8 weeks later another 50mg, and then 8 weeks later he increased it by 25mg. I think I am good to go now. I really couldn't tell it helped until recently. I also have been taking Entocort to help me get by until the Imuran kicked in. I am weaning off the Entocort now. I get my blood tested regularly and everything so far is good. Fingers crossed! F 54 5 months
7/26/2008
 1  Auto Immune Hepatitis 2 hours after taking the pill for the first time, became violently ill, vomiting and diarrhea at the same time. At times blood both ways also. Immense pain in stomach. Became uncontrollable. This lasted for over an hour when my office called the paramedics. My stomach lining was being torn up by the pill. Two days after being off the pill, I was fine. I would not recommend this pill to anyone. I have been taking prednisone for over two years. I have gained over 50 pounds and my face in quite full. However, can live with these sides effects without hesitation compared to those of Imuran. Imuran is a nasty drug with too many bad side effects. Don't take it. F 60 1 days
7/26/2008
 1  Crohn's disease acne and consequently acne scars, tumors, vomiting, yellowing of skin, it severely suppressed my immune system and i was sick the whole time i was on it. i felt very weak. i played sports in high school. never after any workout did i feel so weak as i did on imuran. also, redspots on skin, fast heartbeat, mouth sores, and i kept getting bruises. I just found out that using drugs like Asacol with Imuran should only be done with extreme caution. I wonder if that's why Imuran didn't work for me and why I only had bad reactions. My skin is still yellow and I've been off Imuran for quite some time now. I wonder if my yellow skin could be a sign of a liver problem? I know Imuran takes a while to get out of your system, but it seems like my skin should return a normal color at some point...i don't like this drug. F 33 7 months
7/24/2008
 4  Autoimmune Hepatitis I had no side effects in the frist year. Reciently I have had my dosage dropped to 50 mg from 100mg and have noticed an increase in hip abduction pain and muscle spasms. I have also found it difficult to take the weight off I gained from the use of prednisone. The muscle spasms are what is really troubling me, because I can not tell if it is a side-effect, withdrawl, or something else completly. I am completly greatful to have my life back thanks to prednisone and imuran. I would like to find more information about any withdrawl symptoms imuran may have. M 32 1.5 years
7/13/2008
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 1  UC Skin growths on face, severe acne (was also on prednisone) that left scars, warts that won't go away, incessant nausea, significant hair loss, and a serious eye infection (Imuran decreases your ability to fight infection.) I would try safer treatments first. My disease was supposedly very severe, and yet I put my disease in remission with just a strict diet and probiotics. The drugs never did anything for my disease, just bad things for my overall health and quality of life. If you know what to expect, of course, you can mitigate and prevent some of the damage the drugs can cause. Still, I'd recommend trying the safer treatments first. For me, they weren't just safer; they were also more effective. M 4 months
6/26/2008
 1  RA Pancreatitis, Severe Gastritis, Nausea, Severe Bruising I took this medication for three weeks, after two weeks I began to feel unwell (like I was getting flu), was covered in bruises, started vomiting but did not connect it with the medication as I had been told nothing. Ended up in hospital with severe pancreatitis, hospital did'nt make the connection between the pancreatitis and the medication and told me to carry on taking it, eventually stopped taking it myself took the hospital 6 weeks to make the connection. I lost six months of my life from taking this medication, thats how long it took me to recover, even now i have stomach problems which have never stopped. The RA Consultant said to me well when you started to feel unwell you should hae stopped taking it, bit difficult when you have been given no warnings and not being told to have your blood tested. If you are ever given this drug, make sure you get your blood tested very early on, if I had i would have known to stop taking it. M 44 21 days
6/25/2008
 2  Polymyositis Hair loss and most recently, affected my liver function so the dr. took me off it altogether! F 46 7 months
6/19/2008
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 1  UC Extreme tiredness, nausea, warts--lots, all over my neck--a rash--I was probably allergic, but I had a really stupid doctor--and a tumor developed on my face--had to have it removed and it left a large, hideous scar. If you absolutely need it, make sure you have a competent, caring doctor. You really need to be monitored closely on this drug. And there are serious risks--like cancer--so keep that in mind. Don't let you doctor brush aside your concerns. If he or she does this, find a different doctor. You really need to know what you're getting into and what to expect BEFORE you use the drug. M 19 6 months
6/2/2008

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