IMURAN Reviews (AZATHIOPRINE)

Average Rating: 2.9 (526 Ratings)

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 IMMUNOMODULATORS ANTIMETABOLITES

 Type: Rx Drug

  

IMURAN  (AZATHIOPRINE):  Azathioprine is used to prevent organ rejection in people who have received a kidney transplant. It is usually taken along with other medications to allow your new kidney to function normally. Azathioprine is also used to treat rheumatoid arthritis. In this condition, the body's defense system (immune system) attacks healthy joints. Azathioprine belongs to a class of drugs known as immunosuppressants. It works by weakening the immune system to help your body accept the new kidney as if it were your own (in the case of an organ transplant) or to prevent further damage to your joints (in the case of rheumatoid arthritis). Talk to your doctor about the risks and benefits of azathioprine, especially when used in children and young adults.    (Sources: U.S. Centers for Medicare Services, FDA)

  

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Key to Ratings: 1=LOW (I would not recommend taking this medicine.)
5=HIGH (this medicine cured me or helped me a great deal.)

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RATING  REASONSIDE EFFECTS FOR IMURANCOMMENTSSEXAGEDURATION/
DOSAGE
DATE ADDED
 
 2  Crohn's Disease Tiredness, lethargy, extreme joint & muscle pains, red/swollen/sore eyes, abdominal pains, infections. Also, acne caused by Prednisolone won't heal since taking Imuran. I wasn't expecting to get side effects of this magnitude so soon (after only being on the drug three weeks) - not when they say it takes several months for the drug to start working! I've now stopped taking it because the side effects have been far, far worse than the disease. The Crohn's combined with the prednisolone side-effects are a pain in the backside (excuse the pun) but at least I still had a life! My disease isn't severe enough to warrant taking a drug this obviously toxic. F 39 4 weeks
100mg 1X day
2/23/2010
 1  Ulcerative Colitis Nausea, skin growths, weakness, tiredness Started getting side effects just after a few months, but my doctor said Imuran wasn't causing them. Stayed on it, side effects continued. Stopped after a year and never had these side effects since. Skin growths, of course, remain though. Changing my diet was more beneficial than taking Imuran. I really recommend making serious changes to your diet before starting a drug like Imuran. The reason why Imuran causes skin growths in many patients is because it has the ability to cause cancer. Your doctor might downplay this, but if it happens to you, well, that really sucks for you and what does it matter to your Dr? He/She might pretend to care, but the fact is most GIs don't; and even if you have one who truly does, it doesn't change anything. Using Imuran is basically throwing your money away, wasting your time going to see your GI (and he/she'll probably just look at you during the appt), and you might get cancer, or just even skin growths and other such things. I see no point in it, not until you've exhausted ALL other options... M 30 1 years
100 1X day
2/19/2010
 1  Colitis Warts on face. Flu-like symptoms. Nausea. Acne. Discolored skin. Someone on healingwell.com who had the same problem with Imuran. I had no positive effect from the medicine, so this is pretty annoying. I can't burn them off or anything, obviously that would leave scarring. So I just have to look sickly and diseased with all these warts. M 30 1 months
100 1X day
2/10/2010
 1  Crohns Extreme pain in abdomen radiating to back My husband was diagnosed with Crohns in August 2009. He started taking Imuran in September when he experienced extreme pain in his abdonmen which radiated through to his back. He seeked medical attention on more than 6 occasions but not one doctor could find the cause of his pain. In late October he was diagnosed with pancreatic cancer which had spread to his liver. This disease is terminal. He passed away in January of 2010 only 9 weeks after being diagnosed (aged 45). We will never know if this medication caused his cancer but I am sure it play some part. I would be extremely cautious about taking Imuran. M 45 14 days
1/31/2010
 1  UC Lost ability to heal! My body heals very, very slowly now. In some ways, I think Imuran suppressed my immune system so much my body just doesn't heal now. Also skin discoloration which sounds minor but makes me very selfconscious. Imuran's side effects can stay with you long after you're off. Some of them don't even show up UNTIL you've stopped using it. This drug is potentially very, very dangerous. Maybe it helps some, but it's also horrible for many. You really need to know that before taking it. F 33 1 years
1/30/2010
 4  autoimmune hepatitis I have hair loss, hot flashes, feel like i have a fever, but don't, just don't feel well. i take 50mg imuran with 10 mg prednisone i have been taking them for 1yr 3 months. i am worried about the side effects but am thankful my liver is good and i can function with no pain F 46 1 years
1/27/2010
 1  auto immune hepatitis & cirrhosis severe abdominal pains, tired all the time, nauesa, back & neck pains, swollen feet,discoloration & jaundice - UTI's frequently I was diagnosed with autoimmune hepatitis, & cirrhosis in 2006. My doctors put me on prednisone and imuran. My levels would go up and down alot so my dozes would get changed alot. About two months ago, i was in school, doing gym class and while i was running i felt a sudden sharp pain my my stomach, along with not being able to catch my breath. The pains inmy stomach were so severe i couldn't even stand up straight. I was then put in the hospital for a week, and my dotors took me completly off of IMURAN. They said that the pains in my abdominal might be caused from the medicine. It is now almost three months later and i'm experiencing severe pains again. I also get UTI's like every month and they are so bad that i can barley even get out of bed. yes i am fourteen, and in those four years from experience, this MEDICINE IS NOT GOOD FOR YOU! F 14 4 years
1/27/2010
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 4  Autoimmune Hepatitis Started at 50 mg for about 6 months and had very mild side effects. Mostly tiredness and hair loss (a lot) I am now on 100 mg (started 2 days ago) so I am not sure if I will have any additional side effects. My liver enzimes came down to normal ranges for the past 6 months and only now they started to climb up again... that is the reason my doctor bumped my dose to 100 mg. I noticed that while it has kept my liver enzimes from going up, it didn't help me with the disease symptoms... strange . I will post another review in 6 months after being for a little while on higher dose. F 41 6 months
1/24/2010
 1  Crohn's Hair loss, vomiting, infections, much harder to get over colds/the flu, decreased healing ability I was on a very high dose. Maybe it's not as bad if your doctor actually knows how to use it. Mine didn't. Unfortunately, gastroenterology is one of those fields most people don't want to go into (understandably, you're constantly sticking your fingers up people's rectums, etc.) so it can be very difficult to find a good GI doctor. M 26 9 months
1/21/2010
 5  Crohns Nausea I am on Salofalk for my Crohns but I developed a fisulta and was given this medication to help it close. It worked very well and I am remaining on it to help keep my Crohns under control. Initially I had sever nausea from the Imuran but I lowered my dose and also split my dose up so I am not taking it all at once and my nausea is gone. F 35 2 years
1/20/2010
 1  UC Tumors, hair loss, nausea, rashes, red bumps, acne If more people were taking Imuran, I bet it'd get pulled from the market or at least black-boxed pretty quickly. I would never want anyone I know taking it. Didn't help my symptoms AT ALL and yet did all sorts of bad things. F 31 1 years
1/18/2010
 5  crohns bells palsy, acne and chest rash at higher doses This drug really turned my life around. Took a couple of months to kick in but allowed me to get off the steroids which caused lots of unpleasant side effects. Started off on 150mg daily and was completely off steroids after 8 months. 2 years ago I dropped my does to 100mg and one year ago dropped to 50mg. Each time I would feel physically better for the first 4 months after dropping the dose then feel real bad for a couple of months and slowly recover over the next 4 months. Would like to stop completely as worried about the cancer issues but also don't want to spend my life in the bathroom again. Have a colonoscopy next month and hope to drop to 25mg daily M 50 9 years
1/15/2010
 4  Crohn's Disease - Fistulas Constant Nausea, Weak, Body Aches, Tired I began taking this drug last April as my Crohn's disease had flared pretty badly and I had fistulizing disease. The Azathioprine is being used in my case to close the fistulas and prevent them from forming. So far the drugs seem to work. I take 100 mg Azathioprine along along with Pentasa 500mg. The nausea is a bit overwhelming, and to combat that I take Ondansetron HCL. I would like to find an alternative. I find some days it's hard to get out of bed. My body gets very tired and weak - not every day, but often enough to know it's a side effect of the Azathioprine. F 28 10 months
1/15/2010
 1  UC Weird skin problems (yellow skin, skin growths, warts, skin not healing when cut), vomiting (and weight loss), chills, extreme fatigue Here's what the Mayo Clinic says: "Azathioprine is a very strong medicine. You and your doctor should talk about the need for this medicine and its risks." ... "Also, because of the way this medicine acts on the body, there is a chance that it might cause other unwanted effects that may not occur until months or years after the medicine is used. These delayed effects may include certain types of cancer, such as leukemia, lymphoma, or skin cancer." M 18 7 months
1/15/2010
 1  UC Massive hair loss, nausea, flu-like symptoms, weakness, tiredness, warts Suppressing your immune system can have really bad effects. I wouldn't recommend taking this drug. It didn't help my UC, but my whole system is out of balance now. M 26 6 months
1/12/2010
 1  Crohn's Large tumors on face, disclored skin, vomiting M 32 1 years
1/7/2010
 3  Pemphigus tired, severe joint pains especially in lower back, pain in hands and ankles, in bed by 6 every day I am not sure it has helped the Pemphigus. I had two rounds of Rituximab in which I saw improvement right away. I am on 150mg of Imuran. This week I took it down to 100mg. I will call my doctor to let him know. I am losing my ability to walk. My legs are very weak. I have very low energy and a lot of pain in my back. F 53 6 months
1/1/2010
 1  Dr said hair loss, fatigue, nausea F 26
12/24/2009
 1  Crohn's Neoplasms, skin growths, yellow skin Not a good drug at all. Even supposing Imuran worked--it didn't for me--the long term effects of the drug are not good, and even the maker of Imuran acknowledges these effects. Would not recommend to anyone. M 27 2 years
12/21/2009
 4  Ulcerative colitis None as of yet F 39 6 months
12/9/2009

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